In vitro antioxidant properties and in vivo lowering blood lipid of Forsythia suspense leaves

Medicinal Chemistry Research

Volumn 19, Issue 7, 2010, Pages 617-628

  Kang, Wenyi ^a   Wang, Jinmei ^a  

^a HENAN UNIVERSITY   (China)

Author keywords

Antioxidant activity; Forsythia suspense leaves; In vitro; In vivo

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); ANTILIPEMIC AGENT; ANTIOXIDANT; CHINESE DRUG; FORSYTHIA SUSPENSE EXTRACT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; JUEMINGJIANGZHI; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; PHILLYGENIN; PINORESINOL; PLANT EXTRACT; QUERCETIN; RUTOSIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; URSOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; FORSYTHIA SUSPENSE; HYPERLIPIDEMIA; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OLEACEAE; PLANT LEAF; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 77956468235     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-009-9217-5     Document Type: Article

References (21)

1. Benzie IFF, Strain JJ (1996) The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Anal Biochem 239:70-76. doi:10.1006/abio.1996.0292
2. Deng YH, Xu KP, Zhang W, Tan GS (2005) Chemical study on Sophora tonkinensisi. Nat Prod Res Dev 17:172-174
3. Guo XY, Wang NL, Yao XS (2006) Chemical constituents of Pholidota yunnanensis Rolfe. J Shenyang Pharm Univ 23:205-208
4. Hou GX, Yang JX (2005) Effects of extract from Forsythia suspensa leaves tea on the increasing ratio of body weight and the heart superoxidation in hyperlipidemic mice. Pharmacol Clin Chin Mater Med 21:51-52
5. Li HB, Chen F (2005) Preparative isolation and purification of phillyrin from the medicinal plant Forsythia suspesa by high-speed counter-current chromatography. J Chromatogr A 1083:102-105. doi:10.1016/j.chroma.2005.06.025
6. Li CF, Song YL, Liu YX, Kang WY (2008) Antioxidant activity of extracts from Lysimachia clethroides. Fine Chem 25:1191-1193
7. Liu JK, Hu L, Dong ZJ, Hu Q (2004) DPPH radical scavenging activity of ten natural p-terphenyl derivatives obtained from three edible mushrooms indigenous to China. Chem Biodivers 1:601-605. doi:10.1002/cbdv.200490050
8. Ming DS, Yu DQ, Yu SS, Liu J, He CH (1999) A new furofuran mono-lactone from Forsythia suspense. JANPR 1:221-226
9. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26:1231-1237. doi:10.1016/S0891-5849(98)00315-3
10. Roaf ASS, Ozaki Y, Rashid MA, Rui J (2001) Dammarane derivatives from the dried fruits of Forsythia suspense. Phytochemistry 815-818. doi:10.1016/S0031-9422(01)00028-0
11. Sang HP, Sung KK, Sung HC (2005) Euonymus alatus prevents the hyperglycemia and hyperlipidemia induced by high-fat diet in ICR mice. J Ethnopharmacol 102:326-331. doi:10.1016/j.jep. 2005.06.041
12. Vinardell MP, Ugartondo V, Mitgans M (2008) Potential applications of antioxidant lignins from different sources. Ind Crops Prod 27:220-223. doi:10.1016/j.indcrop.2007.07.011
13. Wang ZQ, Wang JX, Feng SM (1996) Study on the chemical constituents of the fruits of Forsythia suspense (Thunb.) Vahl. Northwest Pharm J 11:14-16
14. Wang JM, Xu QT, Kang WY (2007) Studies on the chemical constituent and pharmaceutical effect of Forsythia suspense. Nat Prod Res Dev 19:153-157
15. Wang H, Gao XD, Zhou GC, Cai L, Yao WB (2008) In vitro and in vivo antioxidant activity of aqueous extract from Choerospondias axillaris fruit. Food Chem 106:888-895. doi:10.1016/j.foodchem. 2007.05.068
16. Xu JJ, He DC (2006) Studies on quercetin. Prac Prev Med 13:1095-1097
17. Yang B, Yang Q, Ding ZT (2007) Chemical constituents from Hedyotis diffusa. J Yunan Univ 29:187-189 Natural Sciences Edition
18. Zhao MH, Wang BC (2008) Lipid-lowering treatment of Juemingzi tablet observed 50 cases of hyperlipidemia. J Pract Tradit Chin Med 24:458-459
19. Zhao YM, Li FR, Yang JX, An XN, Zhou MJ (2005a) Effect of phillyrin on the anti-obesity in nutritive obesity mice. Shanxi J Trad Chin Med 26:602-603
20. Zhao YM, Li FR, Yang JX, Liang J, Zhang LS (2005b) Study on the reducing blood lipid and antioxidition effects of phillyrin. Nat Prod Res Dev 17:157-159
21. Zou YH, Li J, Lu C (2006) High-fat emulsion-induced rat model of nonalcoholic steatohepatitis. Life Sci 79:1100-1107. doi:10.1016/j.lfs.2006.03. 021