Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic

Biomedicine and Pharmacotherapy

Volumn 64, Issue 7, 2010, Pages 493-498

  Uys, J D ^b   Manevich, Y ^b   DeVane, L C ^b   He, L ^b   Garret, T E ^b   Pazoles, C J ^c   Tew, K D ^b   Townsend, D M ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c Novelos Therapeutics Inc   (United States)

Author keywords

Glutathione; Glutathionylation; Pharmacokinetics

Indexed keywords

GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE REDUCTASE; NOV 002; THIOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ELIMINATION; DRUG HALF LIFE; MOUSE; NONHUMAN; NONLINEAR SYSTEM; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

ANIMALS; CISPLATIN; DRUG COMBINATIONS; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE REDUCTASE; MICE; MICE, INBRED C57BL; NONLINEAR DYNAMICS; OXIDATION-REDUCTION; OXIDATIVE STRESS; SULFHYDRYL COMPOUNDS; TISSUE DISTRIBUTION;

EID: 77956446962     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2010.01.003     Document Type: Article

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