Mapping quantitative trait loci in a non-equilibrium population

Statistical Applications in Genetics and Molecular Biology

Volumn 9, Issue 1, 2010, Pages

  Wu, Song ^a   Yang, Jie ^b   Wu, Rongling ^a  

^a BEIJING FORESTRY UNIVERSITY   (China)

^b St Jude Children's Research Hospital   (China)

Author keywords

linkage disequilibrium; non equilibrium population; QTL; zygotic model

Indexed keywords

ARTICLE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HUMAN; POPULATION GENETICS; QUANTITATIVE TRAIT LOCUS MAPPING; SIMULATION; BIOLOGICAL MODEL; CHROMOSOME MAP; GENE LINKAGE DISEQUILIBRIUM; GENETIC DATABASE; GENETIC MARKER; GENETICS; METHODOLOGY; QUANTITATIVE TRAIT LOCUS; STATISTICAL ANALYSIS;

CHROMOSOME MAPPING; DATA INTERPRETATION, STATISTICAL; DATABASES, GENETIC; GENETIC MARKERS; GENOTYPE; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; QUANTITATIVE TRAIT LOCI;

EID: 77956413777     PISSN: None     EISSN: 15446115     Source Type: Journal    
DOI: 10.2202/1544-6115.1578     Document Type: Article

References (25)

1. Barton, N. H., and K. S. Gale (1993) Genetic Analysis of Hybrid Zones in Hybrid Zones and the Evolutionary Process. Oxford University Press, Oxford.
2. Bennett, J. H., and F. E. Binet (1956) Association between Mendelian factors with mixed selfing and random mating. Heredity 10: 51-55.
3. Charlesworth, B. (1991) The evolution of sex chromosomes. Science 251: 10301033.
4. Churchill, G. A., and R. W. Doerge (1994) Empirical Threshold values for quantitative trait mapping. Genetics 138: 963-971.
5. Farnir, F., B. Grisart, W. Coppieters, J. Riquet et al. (2002) Simultaneous mining of linkage and LD to fine map QTL in outbreed half-sib pedigrees: revisiting the location of a QTL with major effect on milk production on bovine chromosome 14. Genetics 161: 275-287.
6. Gomes, I., A. Collins, C. Lonjou, N. S. Thomas et al. (1999) Hardy-Weinberg quality control. Ann Hum Genet 63: 535-538.
7. Greenwood, P. E. (1996) A Guide to Chi-squared Testing. New York: John Wiley & Sons.
8. Haldane, J. B. S. (1949) The association of characters as a result of inbreeding and linkage. Ann Eugen 15: 15-23.
9. Hedrick, P. W. (1987) Gametic disequilibrium measures: proceed with caution. Genetics 117: 331-341.
10. Hosking, L., S. Lumsden, K. Lewis, A. Yeo et al. (2004) Detection of genotyping errors by Hardy-Weinberg equilibrium testing. Eur J Hum Genet 12: 395399.
11. Kruglyak, L. (1999) Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat Genet 22: 139-144.
12. Lewontin, R. C. (1964) The interaction of selection and linkage. I. General considerations; heterotic models. Genetics 49: 49-67.
13. Lin, D. Y., and D. Zeng (2006) Likelihood-based inference on haplotype effects in genetic association studies (with discussion). J Am Stat Assoc 101: 89-118.
14. Liu, T., R. J. Todhunter, S. Wu, W. Hou et al. (2007) A random model for mapping imprinted quantitative trait loci in a structured pedigree: An implication for mapping canine hip dysphasia. Genomics 90: 276-284.
15. Lou, X. Y., G. Casella, R. C. Littell, M. C. K. Yang et al. (2003) A haplotype-based algorithm for multilocus linkage disequilibrium mapping of quantitative trait loci with epistasis. Genetics 163 (4): 1533-1548.
16. Lynch, M., and B. Walsh (1998) Genetics and Analysis of Quantitative Traits. Sin-auer Associates, Sunderland, MA.
17. McRae, A. F., J. C. Mcewan, K. G. Dodds, T. Wilson et al. (2002) Linkage disequilibrium in domestic sheep. Genetics 160: 1113-1122.
18. Wahlund, S. (1928) Zusammensetzung von Population und Korrelationserschein-ung vom Standpunkt der Vererbungslehre aus betrachtet. Hereditas 11: 65106.
19. Weir, B. (1996) Genetic Data Analysis II. Sinauer Associates, Sunderland, MA.
20. Wittke-Thompson, J. K., A. Pluzhnikov and N. J. Cox (2005) Rational inferences about departures from Hardy-Weinberg equilibrium. Am J of Hum Genet 76: 967-968.
21. Wu, R. L., and Z. B. Zeng (2001) Joint linkage and linkage disequilibrium mapping in natural populations. Genetics 157: 899-909.
22. Wu, R. L., C. X. Ma and G. Casella (2002) Joint linkage and linkage disequilibrium mapping of quantitative trait loci in natural populations. Genetics 160: 779792.
23. Wu, R. L., C. X. Ma and G. Casella (2007) Statistical Genetics of Quantitative Traits: Linkage, Maps, and QTL. New York: Springer-Verlag.
24. Yang, R. C. (2000) Zygotic associations and multilocus statistics in a nonequilib-rium diploid population. Genetics 155: 1449-1458.
25. Yang, R. C. (2002) Analysis of multilocus zygotic associations. Genetics 161: 43545.