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Volumn 20, Issue 4, 2009, Pages 227-237

Progression in atherosclerosis: Histological features and pathophysiology of atherosclerotic lesions

Author keywords

atherosclerosis; classification; histology; lipid core; neovascularization

Indexed keywords

ARTERIAL WALL THICKENING; ARTERY INTIMA PROLIFERATION; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CALCIFICATION; DISEASE CLASSIFICATION; DISEASE COURSE; HISTOLOGY; HUMAN; INFLAMMATION; INFLAMMATORY INFILTRATE; MACROPHAGE; NEOVASCULARIZATION (PATHOLOGY); PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; THROMBOGENESIS; VASCULAR LESION; XANTHOMA;

EID: 77956410145     PISSN: 08993459     EISSN: None     Source Type: Journal    
DOI: 10.1097/RMR.0b013e3181ea2869     Document Type: Review
Times cited : (12)

References (37)
  • 1
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. Atherosclerosis. Nature. 2000;407:233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 2
    • 0023685291 scopus 로고
    • Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries
    • Glagov S, Zarins C, Giddens DP, et al. Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries. Arch Pathol Lab Med. 1988;112:1018-1031.
    • (1988) Arch Pathol Lab Med , vol.112 , pp. 1018-1031
    • Glagov, S.1    Zarins, C.2    Giddens, D.P.3
  • 3
    • 0027257233 scopus 로고
    • Lipoprotein lipase and sphingomyelinase synergistically enhance the association of atherogenic lipoproteins with smooth muscle cells and extracellular matrix. A possible mechanism for low density lipoprotein and lipoprotein(a) retention and macrophage foam cell formation
    • Tabas I, Li Y, Brocia RW, et al. Lipoprotein lipase and sphingomyelinase synergistically enhance the association of atherogenic lipoproteins with smooth muscle cells and extracellular matrix. A possible mechanism for low density lipoprotein and lipoprotein(a) retention and macrophage foam cell formation. J Biol Chem. 1993;268:20419-21432.
    • (1993) J Biol Chem , vol.268 , pp. 20419-21432
    • Tabas, I.1    Li, Y.2    Brocia, R.W.3
  • 4
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis and coronary disease
    • Hansson GK. Inflammation, atherosclerosis and coronary disease. N Engl J Med. 2005;352:1685-1695.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 5
    • 0034019601 scopus 로고    scopus 로고
    • Lessons from sudden coronary death, a comprehensive morphological classification scheme for atherosclerotic lesions
    • Virmani R, Kolodgie FD, Burke AP, et al. Lessons from sudden coronary death, a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 2000;20:1262.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1262
    • Virmani, R.1    Kolodgie, F.D.2    Burke, A.P.3
  • 6
    • 24944513945 scopus 로고    scopus 로고
    • Atherothrombosis and high-risk plaque: Part I: Evolving concepts
    • Fuster V, Moreno PR, Fayad ZA, et al. Atherothrombosis and high-risk plaque: part I: evolving concepts. JAm Coll Cardiol. 2005;46:937-954.
    • (2005) JAm Coll Cardiol , vol.46 , pp. 937-954
    • Fuster, V.1    Moreno, P.R.2    Fayad, Z.A.3
  • 7
    • 0034691108 scopus 로고    scopus 로고
    • Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice
    • Schonbeck U, Sukhova GK, Shimizu K, et al. Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice. Proc Natl Acad Sci USA. 2000;97:7458-7463.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7458-7463
    • Schonbeck, U.1    Sukhova, G.K.2    Shimizu, K.3
  • 9
    • 26244463577 scopus 로고    scopus 로고
    • Atherosclerotic plaque progression and vulnerability to rupture: Angiogenesis as a source of intraplaque hemorrhage
    • Virmani R, Kolodgie FD, Burke AP, et al. Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arterioscler Thromb Vasc Biol. 2005;25:2054-2061.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2054-2061
    • Virmani, R.1    Kolodgie, F.D.2    Burke, A.P.3
  • 10
    • 0344235454 scopus 로고    scopus 로고
    • Intraplaque hemorrhage and progression of coronary atheroma
    • Kolodgie FD, Gold HK, Burke AP, et al. Intraplaque hemorrhage and progression of coronary atheroma. N Engl J Med. 2003;349:2316-2325.
    • (2003) N Engl J Med , vol.349 , pp. 2316-2325
    • Kolodgie, F.D.1    Gold, H.K.2    Burke, A.P.3
  • 11
    • 20344382053 scopus 로고    scopus 로고
    • Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques. A high-resolution magnetic resonance imaging study
    • Takaya N, Yuan C, Chu B, et al. Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques. A high-resolution magnetic resonance imaging study. Circulation. 2005;111:2768-2775.
    • (2005) Circulation , vol.111 , pp. 2768-2775
    • Takaya, N.1    Yuan, C.2    Chu, B.3
  • 12
    • 66749187756 scopus 로고    scopus 로고
    • Novel concepts in atherogenesis: Angiogenesis and hypoxia in atherosclerosis
    • Sluimer JC, Daemen MJ. Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis. J Pathol. 2009;218:7-29.
    • (2009) J Pathol , vol.218 , pp. 7-29
    • Sluimer, J.C.1    Daemen, M.J.2
  • 13
    • 0026597265 scopus 로고
    • A definition of the intima of human arteries and of its atherosclerosis-prone regions
    • Stary HC, Blankendorn DH, Chandler AB, et al. A definition of the intima of human arteries and of its atherosclerosis-prone regions. Arterioscler Thromb. 1992;12:120-134.
    • (1992) Arterioscler Thromb , vol.12 , pp. 120-134
    • Stary, H.C.1    Blankendorn, D.H.2    Chandler, A.B.3
  • 14
    • 0028208606 scopus 로고
    • A definition of initial, fatty streak, and intermediate lesions of atherosclerosis
    • Stary HC, Chandler AB, Glagov S, et al. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. Arterioscler Thromb. 1994;14:840-856.
    • (1994) Arterioscler Thromb , vol.14 , pp. 840-856
    • Stary, H.C.1    Chandler, A.B.2    Glagov, S.3
  • 15
    • 0029097154 scopus 로고
    • A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis
    • Stary HC, Chandler AB, Dinsmore RE, et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. Circulation. 1995;92:1355-1374.
    • (1995) Circulation , vol.92 , pp. 1355-1374
    • Stary, H.C.1    Chandler, A.B.2    Dinsmore, R.E.3
  • 16
    • 33744992900 scopus 로고    scopus 로고
    • Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms: The Oxford Plaque Study
    • Redgrave JNE, Lovett JK, Gallagher PJ, et al. Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms: the Oxford Plaque Study. Circulation. 2006;113:2320-2328.
    • (2006) Circulation , vol.113 , pp. 2320-2328
    • Jne, R.1    Lovett, J.K.2    Gallagher, P.J.3
  • 17
    • 34848826028 scopus 로고    scopus 로고
    • Artery-related differences in atherosclerosis expression. Implications for atherogenesis and dynamics in intima-media thickness
    • Dalager S, Paaske WP, Kristensen IB, et al. Artery-related differences in atherosclerosis expression. Implications for atherogenesis and dynamics in intima-media thickness. Stroke. 2007;38:2698-2705.
    • (2007) Stroke , vol.38 , pp. 2698-2705
    • Dalager, S.1    Paaske, W.P.2    Kristensen, I.B.3
  • 18
    • 0028085059 scopus 로고
    • Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology
    • van der Wal AC, Becker AE, van der Loos CM, et al. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation. 1994;89:36-44.
    • (1994) Circulation , vol.89 , pp. 36-44
    • Van Der Wal, A.C.1    Becker, A.E.2    Van Der Loos, C.M.3
  • 19
    • 0029876139 scopus 로고    scopus 로고
    • Coronary plaque erosion without rupture into a lipid core: A frequent cause of coronary thrombosis in sudden coronary death
    • Farb A, Burke AP, Tang AL, et al. Coronary plaque erosion without rupture into a lipid core: a frequent cause of coronary thrombosis in sudden coronary death. Circulation. 1996;93:1354-1363.
    • (1996) Circulation , vol.93 , pp. 1354-1363
    • Farb, A.1    Burke, A.P.2    Tang, A.L.3
  • 20
    • 0030961921 scopus 로고    scopus 로고
    • Coronary risk factors and plaque morphology in men with coronary disease who died suddenly
    • Burke AP, Farb A, Malcom GT, et al. Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. N Engl J Med. 1997;336:1276-1282.
    • (1997) N Engl J Med , vol.336 , pp. 1276-1282
    • Burke, A.P.1    Farb, A.2    Malcom, G.T.3
  • 21
    • 0034020018 scopus 로고    scopus 로고
    • Natural history and histologic classification of atherosclerotic lesions: An update
    • Stary HC. Natural history and histologic classification of atherosclerotic lesions: an update. Arterioscler Thromb Vasc Biol. 2000;20:1177-1178.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1177-1178
    • Stary, H.C.1
  • 22
    • 0018826085 scopus 로고
    • Atherosclerotic involvement of the coronary arteries of adolescents and young adults
    • Velican D, Velican C. Atherosclerotic involvement of the coronary arteries of adolescents and young adults. Atherosclerosis. 1980;36:449-460.
    • (1980) Atherosclerosis , vol.36 , pp. 449-460
    • Velican, D.1    Velican, C.2
  • 23
    • 39049178521 scopus 로고    scopus 로고
    • Histopathology of carotid atherosclerotic disease
    • Virmani R, Ladich ER, Burke AP, et al. Histopathology of carotid atherosclerotic disease. Neurosurgery. 2006;56:S219-S227.
    • (2006) Neurosurgery , vol.56
    • Virmani, R.1    Ladich, E.R.2    Burke, A.P.3
  • 24
    • 46249096932 scopus 로고    scopus 로고
    • Critical cap thickness and rupture in symptomatic carotid plaques: The Oxford Plaque Study
    • Redgrave JN, Gallagher P, Lovett JK, et al. Critical cap thickness and rupture in symptomatic carotid plaques: the Oxford Plaque Study. Stroke. 2008;39:1722-1729.
    • (2008) Stroke , vol.39 , pp. 1722-1729
    • Redgrave, J.N.1    Gallagher, P.2    Lovett, J.K.3
  • 25
    • 5644234911 scopus 로고    scopus 로고
    • Histological correlates of carotid plaque surface morphology on lumen contrast imaging
    • Lovett JK, Gallagher PJ, Hands LJ, et al. Histological correlates of carotid plaque surface morphology on lumen contrast imaging. Circulation. 2004;110:2190-2197.
    • (2004) Circulation , vol.110 , pp. 2190-2197
    • Lovett, J.K.1    Gallagher, P.J.2    Hands, L.J.3
  • 26
    • 0037339854 scopus 로고    scopus 로고
    • Phagocytosis and macrophage activation associated with hemorrhagic microvessels in human atherosclerosis
    • Kockx MM, Cromheeke KM, Knaapen MW, et al. Phagocytosis and macrophage activation associated with hemorrhagic microvessels in human atherosclerosis. Arterioscler Thromb Vasc Biol. 2003;23:440-446.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 440-446
    • Kockx, M.M.1    Cromheeke, K.M.2    Knaapen, M.W.3
  • 27
    • 66349092815 scopus 로고    scopus 로고
    • Mechanisms and consequences of macrophage apoptosis in atherosclerosis
    • Seimon T, Tabas I. Mechanisms and consequences of macrophage apoptosis in atherosclerosis. J Lipid Res. 2009;50:S382-S387.
    • (2009) J Lipid Res , vol.50
    • Seimon, T.1    Tabas, I.2
  • 28
    • 44449179339 scopus 로고    scopus 로고
    • Comparison of lipid-rich necrotic core size in symptomatic and asymptomatic carotid atherosclerotic plaque: Initial results
    • Cappendijk VC, Kessels AGH, Heeneman S, et al. Comparison of lipid-rich necrotic core size in symptomatic and asymptomatic carotid atherosclerotic plaque: initial results. JMagn Reson Imaging. 2008;27:1356-1361.
    • (2008) JMagn Reson Imaging , vol.27 , pp. 1356-1361
    • Cappendijk, V.C.1    Agh, K.2    Heeneman, S.3
  • 29
    • 44449153568 scopus 로고    scopus 로고
    • Comparison of single-sequence T1w TFE MRI with multisequence MRI for the quantification of lipid-rich necrotic core in atherosclerotic plaque
    • Cappendijk VC, Heeneman S, Kessels AGH, et al. Comparison of single-sequence T1w TFE MRI with multisequence MRI for the quantification of lipid-rich necrotic core in atherosclerotic plaque. J Magn Reson Imaging. 2008;27:1347-1355.
    • (2008) J Magn Reson Imaging , vol.27 , pp. 1347-1355
    • Cappendijk, V.C.1    Heeneman, S.2    Agh, K.3
  • 30
    • 53749101001 scopus 로고    scopus 로고
    • In vivo 3D high-spatial-resolution MR imaging of intraplaque hemorrhage
    • Bitar R, Moody AR, Leung G, et al. In vivo 3D high-spatial-resolution MR imaging of intraplaque hemorrhage. Radiology. 2008;249:259-267.
    • (2008) Radiology , vol.249 , pp. 259-267
    • Bitar, R.1    Moody, A.R.2    Leung, G.3
  • 31
    • 8144220036 scopus 로고    scopus 로고
    • Arterial neovascularization and inflammation in vulnerable patients. Early and late signs of symptomatic atherosclerosis
    • Fleiner M, Kummer M, Mirlacher M, et al. Arterial neovascularization and inflammation in vulnerable patients. Early and late signs of symptomatic atherosclerosis. Circulation. 2004;110:2843-2850.
    • (2004) Circulation , vol.110 , pp. 2843-2850
    • Fleiner, M.1    Kummer, M.2    Mirlacher, M.3
  • 32
    • 4944229954 scopus 로고    scopus 로고
    • Plaque neovascularization is increased in ruptured atherosclerotic lesions of human aorta: Implications for plaque vulnerability
    • Moreno PR, Purushothaman KR, Fuster V, et al. Plaque neovascularization is increased in ruptured atherosclerotic lesions of human aorta: implications for plaque vulnerability. Circulation. 2004;110:2032-2038.
    • (2004) Circulation , vol.110 , pp. 2032-2038
    • Moreno, P.R.1    Purushothaman, K.R.2    Fuster, V.3
  • 33
    • 33646816714 scopus 로고    scopus 로고
    • Neovascularization in human atherosclerosis
    • Moreno PR, Purushothaman KR, Sirol M, et al. Neovascularization in human atherosclerosis. Circulation. 2006;113:2245-2252.
    • (2006) Circulation , vol.113 , pp. 2245-2252
    • Moreno, P.R.1    Purushothaman, K.R.2    Sirol, M.3
  • 35
    • 0035902442 scopus 로고    scopus 로고
    • Effects of lipid-lowering by simvastatin on human atherosclerotic lesions. A longitudinal study by high-resolution, non-invasive magnetic resonance imaging
    • Corti R, Fayad ZA, Juster V, et al. Effects of lipid-lowering by simvastatin on human atherosclerotic lesions. A longitudinal study by high-resolution, non-invasive magnetic resonance imaging. Circulation. 2001;104:249-252.
    • (2001) Circulation , vol.104 , pp. 249-252
    • Corti, R.1    Fayad, Z.A.2    Juster, V.3
  • 36
    • 0033528660 scopus 로고    scopus 로고
    • Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice
    • Moulton KS, Heller E, Konerding MA, et al. Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Circulation. 1999;99:1726-1732.
    • (1999) Circulation , vol.99 , pp. 1726-1732
    • Moulton, K.S.1    Heller, E.2    Konerding, M.A.3
  • 37
    • 0344921396 scopus 로고    scopus 로고
    • Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis
    • Moulton KS, Vakili K, Zurakowski D, et al. Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis. Proc Natl Acad Sci USA. 2003;100:4736-4741.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4736-4741
    • Moulton, K.S.1    Vakili, K.2    Zurakowski, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.