Linking incomplete reprogramming to the improved pluripotency of murine embryonal carcinoma cell-derived pluripotent stem cells

PLoS ONE

Volumn 5, Issue 4, 2010, Pages

  Chang, Gang ^a,b,c   Miao, Yi Liang ^a,b   Zhang, Yu ^b   Liu, Sheng ^b   Kou, Zhaohui ^b   Ding, Junjun ^b   Chen, Da Yuan ^a   Sun, Qing Yuan ^a   Gao, Shaorong ^b  

^a INSTITUTE OF ZOOLOGY   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR NANOG; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CELL AGGREGATION; CELL NUCLEUS; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; EMBRYONAL CARCINOMA STEM CELL; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; GENOME IMPRINTING; H19 GENE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; OOCYTE; PLURIPOTENT STEM CELL; PROMOTER REGION; TETRAPLOIDY; ANIMAL; CYTOLOGY; METABOLISM; TRANSCRIPTION INITIATION; ULTRASTRUCTURE;

ANIMALS; CELL NUCLEUS; DNA METHYLATION; EMBRYONAL CARCINOMA STEM CELLS; FEMALE; INDUCED PLURIPOTENT STEM CELLS; MICE; NUCLEAR REPROGRAMMING; OOCYTES; PLURIPOTENT STEM CELLS; TRANSCRIPTIONAL ACTIVATION;

EID: 77956406799     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010320     Document Type: Article

References (51)

1. Campbell KH, McWhir J, Ritchie WA, Wilmut I (1996) Sheep cloned by nuclear transfer from a cultured cell line. Nature 380: 64-66.
2. Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R (1998) Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 394: 369-374.
3. Hochedlinger K, Jaenisch R (2002) Monoclonal mice generated by nuclear transfer from mature B and T donor cells. Nature 415: 1035-1038.
4. Eggan K, Baldwin K, Tackett M, Osborne J, Gogos J, et al. (2004) Mice cloned from olfactory sensory neurons. Nature 428: 44-49.
5. Li J, Ishii T, Feinstein P, Mombaerts P (2004) Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons. Nature 428: 393-399.
6. Inoue K, Wakao H, Ogonuki N, Miki H, Seino K, et al. (2005) Generation of cloned mice by direct nuclear transfer from natural killer T cells. Curr Biol 15: 1114-1118.
7. Rideout WM, 3rd, Eggan K, Jaenisch R (2001) Nuclear cloning and epigenetic reprogramming of the genome. Science 293: 1093-1098.
8. Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
9. Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415-428.
10. Herman JG, Baylin SB (2003) Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349: 2042-2054.
11. Kleinsmith LJ, Pierce GB, Jr. (1964) Multipotentiality of Single Embryonal Carcinoma Cells. Cancer Res 24: 1544-1551.
12. Martin GR (1980) Teratocarcinomas and mammalian embryogenesis. Science 209: 768-776.
13. Brinster RL (1974) The effect of cells transferred into the mouse blastocyst on subsequent development. J Exp Med 140: 1049-1056.
14. Li L, Connelly MC, Wetmore C, Curran T, Morgan JI (2003) Mouse embryos cloned from brain tumors. Cancer Res 63: 2733-2736.
15. Hochedlinger K, Blelloch R, Brennan C, Yamada Y, Kim M, et al. (2004) Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev 18: 1875-1885.
16. Blelloch RH, Hochedlinger K, Yamada Y, Brennan C, Kim M, et al. (2004) Nuclear cloning of embryonal carcinoma cells. Proc Natl Acad Sci U S A 101: 13985-13990.
17. Takahashi K, Mitsui K, Yamanaka S (2003) Role of ERas in promoting tumourlike properties in mouse embryonic stem cells. Nature 423: 541-545.
18. Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, et al. (2009) Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460: 1132-1135.
19. Raychaudhuri S, Stuart JM, Altman RB (2000) Principal components analysis to summarize microarray experiments: application to sporulation time series. Pac Symp Biocomput. pp 455-466.
20. Guillou L, Estreicher A, Chaubert P, Hurlimann J, Kurt AM, et al. (1996) Germ cell tumors of the testis overexpress wild-type p53. Am J Pathol 149: 1221-1228.
21. Moore BE, Banner BF, Gokden M, Woda B, Liu Y, et al. (2001) p53: a good diagnostic marker for intratubular germ cell neoplasia, unclassified. Appl Immunohistochem Mol Morphol 9: 203-206.
22. Brannan CI, Dees EC, Ingram RS, Tilghman SM (1990) The product of the H19 gene may function as an RNA. Mol Cell Biol 10: 28-36.
23. Wakayama T, Rodriguez I, Perry AC, Yanagimachi R, Mombaerts P (1999) Mice cloned from embryonic stem cells. Proc Natl Acad Sci U S A 96: 14984-14989.
24. Kim JB, Sebastiano V, Wu G, Arauzo-Bravo MJ, Sasse P, et al. (2009) Oct4-induced pluripotency in adult neural stem cells. Cell 136: 411-419.
25. Okita K, Ichisaka T, Yamanaka S (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317.
26. Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, et al. (2007) In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448: 318-324.
27. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
28. Li W, Wei W, Zhu S, Zhu J, Shi Y, et al. (2009) Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell 4: 16-19.
29. Liao J, Cui C, Chen S, Ren J, Chen J, et al. (2009) Generation of induced pluripotent stem cell lines from adult rat cells. Cell Stem Cell 4: 11-15.
30. Ko K, Tapia N, Wu G, Kim JB, Bravo MJ, et al. (2009) Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell 5: 87-96.
31. Yamanaka S (2007) Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell 1: 39-49.
32. Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, et al. (2009) Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature 460: 1145-1148.
33. Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, et al. (2009) Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 460: 1140-1144.
34. Li H, Collado M, Villasante A, Strati K, Ortega S, et al. (2009) The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 460: 1136-1139.
35. Marion RM, Strati K, Li H, Murga M, Blanco R, et al. (2009) A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature 460: 1149-1153.
36. Oren M, Reich NC, Levine AJ (1982) Regulation of the cellular p53 tumor antigen in teratocarcinoma cells and their differentiated progeny. Mol Cell Biol 2: 443-449.
37. Curtin JC, Spinella MJ (2005) p53 in human embryonal carcinoma: identification of a transferable, transcriptional repression domain in the N-terminal region of p53. Oncogene 24: 1481-1490.
38. Rowland BD, Bernards R, Peeper DS (2005) The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat Cell Biol 7: 1074-1082.
39. Chen X, Xu H, Yuan P, Fang F, Huss M, et al. (2008) Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133: 1106-1117.
40. Chambers I, Colby D, Robertson M, Nichols J, Lee S, et al. (2003) Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113: 643-655.
41. Niwa H, Burdon T, Chambers I, Smith A (1998) Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 12: 2048-2060.
42. Ying QL, Nichols J, Chambers I, Smith A (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115: 281-292.
43. Silva J, Nichols J, Theunissen TW, Guo G, van Oosten AL, et al. (2009) Nanog is the gateway to the pluripotent ground state. Cell 138: 722-737.
44. Bartolomei MS, Zemel S, Tilghman SM (1991) Parental imprinting of the mouse H19 gene. Nature 351: 153-155.
45. Reik W, Brown KW, Slatter RE, Sartori P, Elliott M, et al. (1994) Allelic methylation of H19 and IGF2 in the Beckwith-Wiedemann syndrome. Hum Mol Genet 3: 1297-1301.
46. Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, et al. (1994) A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367: 645-648.
47. Visvader JE, Lindeman GJ (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8: 755-768.
48. Rosen JM, Jordan CT (2009) The increasing complexity of the cancer stem cell paradigm. Science 324: 1670-1673.
49. Chang G, Liu S, Wang F, Zhang Y, Kou Z, et al. (2009) Differential methylation status of imprinted genes in nuclear transfer derived ES (NT-ES) cells. Genomics 93: 112-119.
50. Nagy A, Gocza E, Diaz EM, Prideaux VR, Ivanyi E, et al. (1990) Embryonic stem cells alone are able to support fetal development in the mouse. Development 110: 815-821.
51. Hosack DA, Dennis G, Jr., Sherman BT, Lane HC, Lempicki RA (2003) Identifying biological themes within lists of genes with EASE. Genome Biol 4: R70.