Antibodies to HLA-E in nonalloimmunized males: Pattern of HLA-Ia reactivity of anti-HLA-E-positive sera

Journal of Immunology

Volumn 185, Issue 3, 2010, Pages 1935-1948

  Ravindranath, Mepur H ^a   Kaneku, Hugo ^a   El Awar, Nadim ^b   Morales Buenrostro, Luis E ^c   Terasaki, Paul I ^a  

^a TERASAKI FOUNDATION LABORATORY   (United States)

^b One Lambda Inc   (United States)

^c INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIBODY; HLA E ANTIBODY; HLA E ANTIGEN; HLA IA ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; RECOMBINANT ANTIGEN; UNCLASSIFIED DRUG; ALLOANTIBODY; AUTOANTIGEN; HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA-E ANTIGEN; MONOCLONAL ANTIBODY;

ALLELE; ALLOIMMUNITY; AMINO ACID SEQUENCE; ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; HUMAN; IMMUNOREACTIVITY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; ADULT; ANIMAL; ANTIBODY AFFINITY; ANTIBODY COMBINING SITE; BIOSYNTHESIS; BLOOD; CLASSIFICATION; COMPARATIVE STUDY; CROSS REACTION; FEMALE; GENETICS; IMMUNIZATION; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MOUSE;

ADULT; ALLELES; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; AUTOANTIGENS; BINDING SITES, ANTIBODY; CROSS REACTIONS; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; ISOANTIBODIES; MALE; MICE; MIDDLE AGED; YOUNG ADULT;

EID: 77956405838     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000424     Document Type: Article

References (52)

1. Geraghty, D. E., B. H. Koller, and H. T. Orr. 1987. A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment. Proc. Natl. Acad. Sci. USA 84: 9145-9149.
2. Geraghty, D. E., X. H. Wei, H. T. Orr, and B. H. Koller. 1990. Human leukocyte antigen F (HLA-F). An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetitive element. J. Exp. Med. 171: 1-18.
3. Koller, B. H., D. E. Geraghty, Y. Shimizu, R. DeMars, and H. T. Orr. 1988. HLA-E. A novel HLA class I gene expressed in resting T lymphocytes. J. Immunol. 141: 897-904.
4. Shawar, S. M., J. M. Vyas, J. R. Rodgers, and R. R. Rich. 1994. Antigen presentation by major histocompatibility complex class I-B molecules. Annu. Rev. Immunol. 12: 839-880.
5. Collins, Z. V., P. F. Arnold, F. Peetoom, G. S. Smith, and R. L. Walford. 1973. A naturally occurring monospecific anti-HL-A8 isoantibody. Tissue Antigens 3: 358-363.
6. Lepage, V., L. Degos, and J. Dausset. 1976. A "natural" anti-HLA-A2 antibody reacting with homozygous cells. Tissue Antigens 8: 139-142.
7. Tongio, M. M., A. Falkenrodt, Y. Mitsuishi, A. Urlacher, J. P. Bergerat, M. L. North, and S. Mayer. 1985. Natural HLA antibodies. Tissue Antigens 26: 271-285.
8. Ameglio, F., F. Saba, A. Bitti, A. Aceti, N. Tanigaki, R. Sorrentino, A. Dolei, and R. Tosi. 1987. Antibody reactivity to HLA classes I and II in sera from patients with hydatidosis. J. Infect. Dis. 156: 673-676.
9. Májský, A. 1989. [Natural HLA-A, B and DR antibodies in the serum of non-immunized men]. Vnitr. Lek. 35: 467-471.
10. Luscher, M. A., G. Choy, J. E. Embree, N. J. Nagelkerke, J. J Bwayo, S. Njenga, F. A. Plummer, B. H. Barber, and K. S. MacDonald. 1998. Anti-HLA alloantibody is found in children but does not correlate with a lack of HIV type 1 transmission from infected mothers. AIDS Res. Hum. Retroviruses 14: 99-107.
11. Zhou, B., S. Saito, Y. Nakazawa, N. Kobayashi, M. Matsuda, Y. Matsumoto, T. Hosoyama, and K. Koike. 2008. Existence of an immunoglobulin G component of naturally occurring HLA class I antibodies that are not directed against self-antigens in human serum. Tissue Antigens 72: 98-104. (Pubitemid 352009809)
12. Morales-Buenrostro, L. E., P. I. Terasaki, L. A. Marino-Vázquez, J. H. Lee, N. El-Awar, and J. Alberú. 2008. "Natural" human leukocyte antigen antibodies found in nonalloimmunized healthy males. Transplantation 86: 1111-1115.
13. Hirata, A. A., and P. I. Terasaki. 1970. Cross-reactions between streptococcal M proteins and human transplantation antigens. Science 168: 1095-1096.
14. Hirata, A. A., F. C. McIntire, P. I. Terasaki, and K. K. Mittal. 1973. Cross reactions between human transplantation antigens and bacterial lipopolysaccharides. Transplantation 15: 441-445.
15. Pellegrino, M. A., S. Ferrone, J. W. Safford, Jr., A. A. Hirata, P. I. Terasaki, and R. A. Reisfeld. 1972. Stimulation of lymphocyte transformation by streptococcal type M1 protein: relationship to HL-A antigens. J. Immunol. 109: 97-102.
16. Archer, J. R. 1981. Search for cross-reactivity between HLA B27 and Klebsiella pneumoniae. Ann. Rheum. Dis. 40: 400-403.
17. Georgopoulos, K., W. C. Dick, J. A. Goodacre, and R. H. Pain. 1985. A reinvestigation of the cross-reactivity between Klebsiella and HLA-B27 in the aetiology of ankylosing spondylitis. Clin. Exp. Immunol. 62: 662-671.
18. Raybourne, R. B., V. K. Bunning, and K. M. Williams. 1988. Reaction of anti-HLA-B monoclonal antibodies with envelope proteins of Shigella species. Evidence for molecular mimicry in the spondyloarthropathies. J. Immunol. 140: 3489-3495.
19. Tsuchiya, N., G. Husby, R. C. Williams, Jr., H. Stieglitz, P. E. Lipsky, and R. D. Inman. 1990. Autoantibodies to the HLA-B27 sequence cross-react with the hypothetical peptide from the arthritis-associated Shigella plasmid. J. Clin. Invest. 86: 1193-1203.
20. Tsuchiya, N., G. Husby, and R. C. Williams, Jr. 1989. Studies of humoral and cell-mediated immunity to peptides shared by HLA-27.1 and Klebsiella pneumoniae nitrogenase in ankylosing spondylitis. Clin. Exp. Immunol. 76: 354-360.
21. Gross, U., J. H. Chen, D. H. Kono, and D. T. Yu. 1990. A ribosomal protein of Yersinia pseudotuberculosis having partial epitope identity with HLA-B27. Autoimmunity 7: 267-277.
22. Esaki, Y., Y. Fukui, T. Sudo, K. Yamamoto, T. Inamitsu, Y. Nishimura, K. Hirokawa, A. Kimura, and T. Sasazuki. 1994. Role of human major histocompatibility complex DQ molecules in superantigenicity of streptococcusderived protein. Infect. Immun. 62: 1228-1235.
23. Ebringer, A., and C. Wilson. 2000. HLA molecules, bacteria and autoimmunity. J. Med. Microbiol. 49: 305-311.
24. Burnet, F. M. 1976. A modification of Jerne's theory of antibody production using the concept of clonal selection. CA Cancer J. Clin. 26: 119-121.
25. Burnet, F. M. 1991. The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1960. Immunologic recognition of self. Scand. J. Immunol. 33: 3-13.
26. Cohen, I. R. 1992. The cognitive paradigm and the immunological homunculus. Immunol. Today 13: 490-494.
27. Cohen, I. R., and D. B. Young. 1991. Autoimmunity, microbial immunity and the immunological homunculus. Immunol. Today 12: 105-110.
28. Nobrega, A., M. Haury, A. Grandien, E. Malanchère, A. Sundblad, and A. Coutinho. 1993. Global analysis of antibody repertoires. II. Evidence for specificity, self-selection and the immunological "homunculus" of antibodies in normal serum. Eur. J. Immunol. 23: 2851-2859.
29. Poletaev, A. B. 2002. The immunological homunculus (immunculus) in normal state and pathology. Biochemistry (Mosc.) 67: 600-608. (Pubitemid 34719967)
30. Merbl, Y., M. Zucker-Toledano, F. J. Quintana, and I. R. Cohen. 2007. Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics. J. Clin. Invest. 117: 712-718.
31. Ravindranath, M. H., M. Taniguchi, C. W. Chen, M. Ozawa, H. Kaneku, N. El-Awar, J. Cai, and P. I. Terasaki. 2010. HLA-E monoclonal antibodies recognize shared peptide sequences on classical HLA class Ia: relevance to human natural HLA antibodies. Mol. Immunol. 47: 1121-1131.
32. Coupel, S., A. Moreau, M. Hamidou, V. Horejsi, J. P. Soulillou, and B. Charreau. 2007. Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation. Blood 109: 2806-2814. (Pubitemid 46482075)
33. Sullivan, L. C., C. S. Clements, J. Rossjohn, and A. G. Brooks. 2008. The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity. Tissue Antigens 72: 415-424.
34. Derré, L., M. Corvaisier, B. Charreau, A. Moreau, E. Godefroy, A. Moreau-Aubry, F. Jotereau, and N. Gervois. 2006. Expression and release of HLA-E by melanoma cells and melanocytes: potential impact on the response of cytotoxic effector cells. J. Immunol. 177: 3100-3107. (Pubitemid 44277827)
35. Lin, Y. J., L. Wan, J. Y. Wu, J. J. Sheu, C. W. Lin, Y. C. Lan, C. H. Lai, C. H. Hung, Y. Tsai, C. H. Tsai, et al. 2009. HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms. Arthritis Rheum. 60: 604-610.
36. El-Awar, N., J. H. Lee, C. Tarsitani, and P. I. Terasaki. 2007. HLA class I epitopes: recognition of binding sites by mAbs or eluted alloantibody confirmed with single recombinant antigens. Hum. Immunol. 68: 170-180.
37. Stastny, P., S. Ring, C. Lu, J. Arenas, M. Han, and B. Lavingia. 2009. Role of immunoglobulin (Ig)-G and IgM antibodies against donor human leukocyte antigens in organ transplant recipients. Hum. Immunol. 70: 600-604.
38. Idica, A., N. Sasaki, S. Hardy, and P. I. Terasaki. 2007. Unexpected frequencies of HLA antibody specificities in the sera of pre-transplant kidney patients. In Clinical Transplants 2006. P. Terasaki, ed. Terasaki Foundation Laboratory, Los Angeles, CA, p. 161.
39. Kinukawa, T., M. Kato. P. I. Terasaki, and M. Ozawa. 2007. Retrospective antibody analysis of thirty patients with kidney graft failure. In Clinical Transplants 2006. P. Terasaki, ed. Terasaki Foundation Laboratory, Los Angeles, CA, p. 291.
40. Mizutani, K., L. Shibata, M. Ozawa, et al. 2007. Detection of HLA and MICA antibodies before kidney graft failure. In Clinical Transplants 2006. P. Terasaki, ed. Terasaki Foundation Laboratory, Los Angeles, CA, p. 255.
41. Ozawa, M. L. M, Rebellato, and P. I. Terasaki. 2007. Longitudinal testing of 266 renal allograft patients for HLA and MICA antibodies: Greenville experience. In Clinical Transplants 2006. P. Terasaki, ed. Terasaki Foundation Laboratory, Los Angeles, CA, p. 265.
42. Rebellato, L. M., M. Ozawa, K. M. Verbanac, P. Catrou, C. E. Haisch, and P. I. Terasaki. 2007. Clinical and anti-HLA antibody profile of nine renal transplant recipients with failed grafts: donor-specific and non-donor-specific antibody development. In Clinical Transplants 2006. P. Terasaki, ed. Terasaki Foundation Laboratory, Los Angeles, CA, p. 241.
43. Ivanyi, P., P. van Mourik, M. Breuning, A. M. Kruisbeek, and C. J. M. Kröse. 1982. Natural H-2-specific antibodies in sera of aged mice. Immunogenetics 15: 95-102.
44. Mirilas, P., C. Fesel, B. Guilbert, N. G. Beratis, and S. Avrameas. 1999. Natural antibodies in childhood: development, individual stability, and injury effect indicate a contribution to immune memory. J. Clin. Immunol. 19: 109-115.
45. Avrameas, S., G. Dighiero, P. Lymberi, and B. Gilbert. 1983. Studies on natural antibodies and autoantibodies. Ann. Immunol. (Paris) 134D: 103-113.
46. Dighiero, G., P. Lymberi, B. Guilbert, T. Ternynck, and S. Avrameas. 1986. Natural autoantibodies constitute a substantial part of normal circulating immunoglobulins. Ann. N. Y. Acad. Sci. 475: 135-145.
47. Berneman, A., B. Guilbert, S. Eschrich, and S. Avrameas. 1993. IgG auto- and polyreactivities of normal human sera. Mol. Immunol. 30: 1499-1510.
48. Ravindranath, M. H., H. Kaneku, and N. El-Awar. 2010. HLA-E monoclonal antibody MEM-E/02 binds to discontinuous but shared peptide sequences on HLA B & C heavy chains not treated by acid. Mol. Immunol. 1663-1664.
49. Ponomarenko, J., H.-H. Bui, W. Li, N. Fusseder, P. E. Bourne, A. Sette, and B. Peters. 2008. ElliPro: a new structure-based tool for the prediction of antibody epitopes. BMC Bioinformatics 9: 514-521.
50. Wu, H. H., Y. C. Tien, C. I. Huang, Y. J. Chiang, S. H. Chu, and P. C. Lai. 2008. HLA class I antibodies in patients awaiting kidney transplantation and the association with renal graft survival. Transplant. Proc. 40: 2191-2194.
51. Briggs, D., D. Zehnder, and R. M. Higgins. 2009. Development of non-donor-specific HLA antibodies after kidney transplantation: frequency and clinical implications. Contrib. Nephrol. 162: 107-116.
52. Seveso, M., E. Bosio, E. Ancona, and E. Cozzi. 2009. De novo anti-HLA antibody responses after renal transplantation: detection and clinical impact. Contrib. Nephrol. 162: 87-98.