The effect of permeation enhancers on the viscosity and the release profile of transdermal hydroxypropyl methylcellulose gel formulations containing diltiazem HCl

Drug Development and Industrial Pharmacy

Volumn 36, Issue 10, 2010, Pages 1195-1206

  Karakatsani, Marianthi ^a   Dedhiya, Mahendra ^a   Plakogiannis, Fotios M ^a  

^a LONG ISLAND UNIVERSITY   (United States)

Author keywords

Diltiazem HCl; Drug binding; Gel formulation; Permeation enhancers; Transdermal delivery; Viscosity

Indexed keywords

1 METHYL 2 PYRROLIDINONE; DILTIAZEM; DIMETHYL SULFOXIDE; DODECYL SULFATE SODIUM; HYDROXYPROPYLMETHYLCELLULOSE; MYRISTIC ACID; MYRISTIC ACID ISOPROPYL ESTER; OCTANOIC ACID; OLEIC ACID; POLYSORBATE 80; PROPYLENE GLYCOL;

ARTICLE; DRUG FORMULATION; GEL; PERMEABILITY; VISCOSITY;

ADMINISTRATION, CUTANEOUS; CALCIUM CHANNEL BLOCKERS; CHEMISTRY, PHARMACEUTICAL; DILTIAZEM; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EXCIPIENTS; FATTY ACIDS; GELS; HUMANS; METHYLCELLULOSE; PERMEABILITY; SKIN; SKIN ABSORPTION; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; VISCOSITY;

EID: 77956396942     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639041003695105     Document Type: Article

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