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Volumn 1, Issue 12, 2009, Pages

Pharmacogenomic insights into treatment and management of statin-induced myopathy

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; ATORVASTATIN; CARNITINE PALMITOYLTRANSFERASE; CERIVASTATIN; CHOLESTEROL; CREATINE KINASE; CYCLOSPORIN A; CYTOCHROME P450; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; FIBRIC ACID DERIVATIVE; FLUINDOSTATIN; MULTIDRUG RESISTANCE PROTEIN 1; ORGANIC ANION TRANSPORTER 2; PRAVASTATIN; PROTEINASE INHIBITOR; SIMVASTATIN; UBIDECARENONE;

EID: 77956394210     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/gm120     Document Type: Review
Times cited : (15)

References (27)
  • 1
    • 0036715223 scopus 로고    scopus 로고
    • ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins.
    • 10.1161/01.str.0000034125.94759.41, 12215610
    • Pasternak RC, Smith SC, Bairey-Merz CN, Grundy SM, Cleeman JI, Lenfant C. ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins. Stroke 2002, 33:2337-2341. 10.1161/01.str.0000034125.94759.41, 12215610.
    • (2002) Stroke , vol.33 , pp. 2337-2341
    • Pasternak, R.C.1    Smith, S.C.2    Bairey-Merz, C.N.3    Grundy, S.M.4    Cleeman, J.I.5    Lenfant, C.6
  • 2
    • 33645881669 scopus 로고    scopus 로고
    • Statin safety: a systematic review.
    • 10.1016/j.amjcard.2005.12.010, 16581329
    • Law M, Rudnicka AR. Statin safety: a systematic review. Am J Cardiol 2006, 97:52C-60C. 10.1016/j.amjcard.2005.12.010, 16581329.
    • (2006) Am J Cardiol , vol.97
    • Law, M.1    Rudnicka, A.R.2
  • 4
    • 32444444724 scopus 로고    scopus 로고
    • Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients - the PRIMO study.
    • 10.1007/s10557-005-5686-z, 16453090
    • Bruckert E, Hayem G, Dejager S, Yau C, Begaud B. Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients - the PRIMO study. Cardiovasc Drugs Ther 2005, 19:403-414. 10.1007/s10557-005-5686-z, 16453090.
    • (2005) Cardiovasc Drugs Ther , vol.19 , pp. 403-414
    • Bruckert, E.1    Hayem, G.2    Dejager, S.3    Yau, C.4    Begaud, B.5
  • 5
    • 34848906510 scopus 로고    scopus 로고
    • Does statin therapy initiation increase the risk for myopathy? An observational study of 32,225 diabetic and nondiabetic patients.
    • 10.1016/j.clinthera.2007.08.022, 17919557
    • Nichols GA, Koro CE. Does statin therapy initiation increase the risk for myopathy? An observational study of 32,225 diabetic and nondiabetic patients. Clin Ther 2007, 29:1761-1770. 10.1016/j.clinthera.2007.08.022, 17919557.
    • (2007) Clin Ther , vol.29 , pp. 1761-1770
    • Nichols, G.A.1    Koro, C.E.2
  • 6
    • 67249111853 scopus 로고    scopus 로고
    • Narrative review: statin-related myopathy.
    • Joy TR, Hegele RA. Narrative review: statin-related myopathy. Ann Intern Med 2009, 150:858-868.
    • (2009) Ann Intern Med , vol.150 , pp. 858-868
    • Joy, T.R.1    Hegele, R.A.2
  • 7
    • 0042627731 scopus 로고    scopus 로고
    • Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers.
    • 10.1016/S0009-9236(03)00121-8, 12891229
    • Kirchheiner J, Kudlicz D, Meisel C, Bauer S, Meineke I, Roots I, Brockmoller J. Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers. Clin Pharmacol Ther 2003, 74:186-194. 10.1016/S0009-9236(03)00121-8, 12891229.
    • (2003) Clin Pharmacol Ther , vol.74 , pp. 186-194
    • Kirchheiner, J.1    Kudlicz, D.2    Meisel, C.3    Bauer, S.4    Meineke, I.5    Roots, I.6    Brockmoller, J.7
  • 8
    • 8644235696 scopus 로고    scopus 로고
    • A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin.
    • 10.1007/s10038-004-0188-6, 15365880
    • Ishikawa C, Ozaki H, Nakajima T, Ishii T, Kanai S, Anjo S, Shirai K, Inoue I. A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin. J Hum Genet 2004, 49:582-585. 10.1007/s10038-004-0188-6, 15365880.
    • (2004) J Hum Genet , vol.49 , pp. 582-585
    • Ishikawa, C.1    Ozaki, H.2    Nakajima, T.3    Ishii, T.4    Kanai, S.5    Anjo, S.6    Shirai, K.7    Inoue, I.8
  • 9
    • 27744472263 scopus 로고    scopus 로고
    • Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis.
    • 10.1111/j.1365-2710.2005.00633_1.x, 15811174
    • Ozaki H, Ishikawa CT, Ishii T, Toyoda A, Murano T, Miyashita Y, Shirai K. Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis. J Clin Pharm Ther 2005, 30:189-192. 10.1111/j.1365-2710.2005.00633_1.x, 15811174.
    • (2005) J Clin Pharm Ther , vol.30 , pp. 189-192
    • Ozaki, H.1    Ishikawa, C.T.2    Ishii, T.3    Toyoda, A.4    Murano, T.5    Miyashita, Y.6    Shirai, K.7
  • 10
    • 20644448824 scopus 로고    scopus 로고
    • Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage.
    • 10.1097/01213011-200506000-00007, 15900215
    • Wilke RA, Moore JH, Burmester JK. Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage. Pharmacogenet Genomics 2005, 15:415-421. 10.1097/01213011-200506000-00007, 15900215.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 415-421
    • Wilke, R.A.1    Moore, J.H.2    Burmester, J.K.3
  • 12
    • 56449116103 scopus 로고    scopus 로고
    • ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin.
    • 10.1038/clpt.2008.25, 19238649
    • Keskitalo JE, Kurkinen KJ, Neuvoneni PJ, Niemi M. ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin. Clin Pharmacol Ther 2008, 84:457-461. 10.1038/clpt.2008.25, 19238649.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 457-461
    • Keskitalo, J.E.1    Kurkinen, K.J.2    Neuvoneni, P.J.3    Niemi, M.4
  • 13
    • 34548103493 scopus 로고    scopus 로고
    • Role of OATP transporters in the disposition of drugs.
    • 10.2217/14622416.8.7.787, 18240907
    • Niemi M. Role of OATP transporters in the disposition of drugs. Pharmacogenomics 2007, 8:787-802. 10.2217/14622416.8.7.787, 18240907.
    • (2007) Pharmacogenomics , vol.8 , pp. 787-802
    • Niemi, M.1
  • 14
    • 33751096467 scopus 로고    scopus 로고
    • SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid.
    • 10.1097/01.fpc.0000230416.82349.90, 17108811
    • Pasanen MK, Neuvonen M, Neuvonen PJ, Niemi M. SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid. Pharmacogenet Genomics 2006, 16:873-879. 10.1097/01.fpc.0000230416.82349.90, 17108811.
    • (2006) Pharmacogenet Genomics , vol.16 , pp. 873-879
    • Pasanen, M.K.1    Neuvonen, M.2    Neuvonen, P.J.3    Niemi, M.4
  • 16
    • 70349739250 scopus 로고    scopus 로고
    • The SLCO1B1 *5 genetic variant is associated with statin-induced side effects.
    • 10.1016/j.jacc.2009.04.053, 19833260
    • Voora D, Shah SH, Spasojevic I, Ali S, Reed CR, Salisbury BA, Ginsburg GS. The SLCO1B1 *5 genetic variant is associated with statin-induced side effects. J Am Coll Cardiol 2009, 54:1609-1616. 10.1016/j.jacc.2009.04.053, 19833260.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1609-1616
    • Voora, D.1    Shah, S.H.2    Spasojevic, I.3    Ali, S.4    Reed, C.R.5    Salisbury, B.A.6    Ginsburg, G.S.7
  • 17
    • 18244401389 scopus 로고    scopus 로고
    • A novel variant allele of OATP-C (SLCO1B1) found in a Japanese patient with pravastatin-induced myopathy.
    • 10.2133/dmpk.19.453, 15681900
    • Morimoto K, Oishi T, Ueda S, Ueda M, Hosokawa M, Chiba K. A novel variant allele of OATP-C (SLCO1B1) found in a Japanese patient with pravastatin-induced myopathy. Drug Metab Pharmacokinet 2004, 19:453-455. 10.2133/dmpk.19.453, 15681900.
    • (2004) Drug Metab Pharmacokinet , vol.19 , pp. 453-455
    • Morimoto, K.1    Oishi, T.2    Ueda, S.3    Ueda, M.4    Hosokawa, M.5    Chiba, K.6
  • 18
    • 67349162117 scopus 로고    scopus 로고
    • Functional analysis of a mutation in the SLCO1B1 gene (c.1628T>G) identified in a Japanese patient with pravastatin-induced myopathy.
    • 10.1038/tpj.2009.3, 19238167
    • Furihata T, Satoh N, Ohishi T, Ugajin M, Kameyama Y, Morimoto K, Matsumoto S, Yamashita K, Kobayashi K, Chiba K. Functional analysis of a mutation in the SLCO1B1 gene (c.1628T>G) identified in a Japanese patient with pravastatin-induced myopathy. Pharmacogenomics J 2009, 9:185-193. 10.1038/tpj.2009.3, 19238167.
    • (2009) Pharmacogenomics J , vol.9 , pp. 185-193
    • Furihata, T.1    Satoh, N.2    Ohishi, T.3    Ugajin, M.4    Kameyama, Y.5    Morimoto, K.6    Matsumoto, S.7    Yamashita, K.8    Kobayashi, K.9    Chiba, K.10
  • 19
    • 28144440151 scopus 로고    scopus 로고
    • The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment.
    • 10.1016/j.clpt.2005.08.003, 16321621
    • Fiegenbaum M, da Silveira FR, Sand CR, Sand LC, Ferreira ME, Pires RC, Hutz MH. The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment. Clin Pharmacol Ther 2005, 78:551-558. 10.1016/j.clpt.2005.08.003, 16321621.
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 551-558
    • Fiegenbaum, M.1    da Silveira, F.R.2    Sand, C.R.3    Sand, L.C.4    Ferreira, M.E.5    Pires, R.C.6    Hutz, M.H.7
  • 20
    • 56249093499 scopus 로고    scopus 로고
    • Genetic predisposition to statin myopathy.
    • 10.1097/BOR.0b013e328314b7b4, 18946323
    • Vladutiu GD. Genetic predisposition to statin myopathy. Curr Opin Rheumatol 2008, 20:648-655. 10.1097/BOR.0b013e328314b7b4, 18946323.
    • (2008) Curr Opin Rheumatol , vol.20 , pp. 648-655
    • Vladutiu, G.D.1
  • 22
    • 0033922177 scopus 로고    scopus 로고
    • Treatment of McArdle disease.
    • 10.1001/archneur.57.7.923, 10891971
    • Haller RG. Treatment of McArdle disease. Arch Neurol 2000, 57:923-924. 10.1001/archneur.57.7.923, 10891971.
    • (2000) Arch Neurol , vol.57 , pp. 923-924
    • Haller, R.G.1
  • 23
    • 33746457868 scopus 로고    scopus 로고
    • Presymptomatic neuromuscular disorders disclosed following statin treatment.
    • 10.1001/archinte.166.14.1519, 16864763
    • Tsivgoulis G, Spengos K, Karandreas N, Panas M, Kladi A, Manta P. Presymptomatic neuromuscular disorders disclosed following statin treatment. Arch Intern Med 2006, 166:1519-1524. 10.1001/archinte.166.14.1519, 16864763.
    • (2006) Arch Intern Med , vol.166 , pp. 1519-1524
    • Tsivgoulis, G.1    Spengos, K.2    Karandreas, N.3    Panas, M.4    Kladi, A.5    Manta, P.6
  • 25
    • 0036517472 scopus 로고    scopus 로고
    • A comprehensive review of genetic association studies.
    • 10.1097/00125817-200203000-00002, 11882781
    • Hirschhorn JN, Lohmueller K, Byrne E, Hirschhorn K. A comprehensive review of genetic association studies. Genet Med 2002, 4:45-61. 10.1097/00125817-200203000-00002, 11882781.
    • (2002) Genet Med , vol.4 , pp. 45-61
    • Hirschhorn, J.N.1    Lohmueller, K.2    Byrne, E.3    Hirschhorn, K.4
  • 27
    • 33749049136 scopus 로고    scopus 로고
    • SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin.
    • 10.1016/j.clpt.2006.06.010, 17015053
    • Niemi M, Pasanen MK, Neuvonen PJ. SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin. Clin Pharmacol Ther 2006, 80:356-366. 10.1016/j.clpt.2006.06.010, 17015053.
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 356-366
    • Niemi, M.1    Pasanen, M.K.2    Neuvonen, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.