A double-blind, randomized clinical trial of the effect of ω-3 fatty acids on the oxidative stress of preterm neonates fed through parenteral nutrition

European Journal of Clinical Nutrition

Volumn 64, Issue 9, 2010, Pages 940-947

  Skouroliakou, M ^a   Konstantinou, D ^b   Koutri, K ^b   Kakavelaki, C ^a   Stathopoulou, M ^a   Antoniadi, M ^b   Xemelidis, N ^c   Kona, V ^a   Markantonis, S ^c  

^a HAROKOPIO UNIVERSITY   (Greece)

^b IASO   (Greece)

^c UNIVERSITY OF ATHENS   (Greece)

Author keywords

3 fatty acids; oxidative stress; parenteral nutrition; preterm neonates; total antioxidant potential

Indexed keywords

ALPHA TOCOPHEROL; BILIRUBIN; C REACTIVE PROTEIN; CREATININE; INTRALIPID; LIPID EMULSION; OMEGA 3 FATTY ACID; RETINOL;

ABSENCE OF SIDE EFFECTS; ANTIOXIDANT ACTIVITY; ARTICLE; ARTIFICIAL VENTILATION; BILIRUBIN BLOOD LEVEL; BIOCHEMISTRY; BODY HEIGHT; BODY TEMPERATURE; BODY WEIGHT; CHILD GROWTH; CLINICAL ARTICLE; CLINICAL EXAMINATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; GREECE; HEAD CIRCUMFERENCE; HEART RATE; HEMATOCRIT; HOSPITAL DISCHARGE; HUMAN; INFANT NUTRITION; LENGTH OF STAY; LEUKOCYTE COUNT; NEWBORN; OXIDATIVE STRESS; PARENTERAL NUTRITION; PHOTOTHERAPY; PREMATURITY; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE COUNT; TREATMENT DURATION; TREATMENT OUTCOME;

ANTIOXIDANTS; DOUBLE-BLIND METHOD; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS, OMEGA-3; FEMALE; GREECE; HUMANS; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFANT, NEWBORN; INFANT, PREMATURE; LENGTH OF STAY; MALE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PARENTERAL NUTRITION; TREATMENT OUTCOME; VITAMIN A; VITAMIN E;

EID: 77956340391     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2010.98     Document Type: Article

References (28)

1. ASPEN Board of Directors (1993). Nutrition support for low birth weight infants. J Parenter Enteral Nutr 17, 33SA-38SA.
2. Antebi H, Mansoor O, Ferrier C, Tetegan M, Morvan C, Rangaraj J et al. (2004). Liver function and plasma antioxidant status in intensive care unit patients requiring total parenteral nutrition: comparison of 2 fat emulsions. J I'arenter Enteral Nutr 28, 142-148.
3. Atkinson SA (2001). Special nutritional needs of infants for prevention of and recovery from bronchopulmonary dysplasia. J Nutr 131, 942S-946S.
4. Blackburn S (2005). Free radicals in perinatal and neonatal care, Part 1: the basics. J Perinat Neonatal Nurs 19, 298-300.
5. Buonocore G, Perrone S, Longini M, Vezzosi P, Marzocchi B, Paffetti P et al. (2002). Oxidative stress in preterm neonates at birth and on the seventh day of life. Pediatr Res 52, 46-49.
6. Calder PC, Jensen GL, Koletzko BV, Singer P, Wanten GJA (2010). Lipid emulsions in parenteral nutrition of intensive care patients: current thinking and future directions. Intensive Care Med 36, 735-749.
7. Darlow BA, Graham PJ (2007). Vitamin A supplementation for preventing morbidity and mortality in very low birth weight infants. Cochrane Database Syst Rev (4). Art. No. CD000501
8. Debier C (2007). Vitamin E during pre- and postnatal periods. Vitam Horm 76, 357-373.
9. Gibson RA, Chen W, Makrides M (2001). Randomized trials with polyunsaturated fatty acid interventions in preterm and term infants: functional and clinical outcomes. Lipids 36, 873-883.
10. Gibsona RA, Chenb W, Makrides M (2001). Randomized trials with polyunsaturated fatty acid interventions in preterm and term infants: functional and clinical outcomes. Lipids 36, 873-883.
11. Gitto E, Pellegrino S, Gitto P, Barberi I, Reiter RJ (2009). Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin. J Pineal Res 46, 128-139.
12. Griffiths HR, Moller L, Bartosz G, Bast A, Bertoni-Freddari C, Collins A et al. (2002). Biomarkers. Mol Aspects Med 23, 101-208.
13. Mactier H, Weaver LT (2005). Vitamin A and preterm infants: what we know, what we don't know, and what we need to know. Arch Dis Child Fetal Neonatal Ed 90, 103-108.
14. Maltepe E, Saugstad OD (2009). Oxygen in health and disease: regulation of oxygen homeostasis-clinical implications. Pediatr Res 65, 261-268.
15. National Advisory Group on Standards and Practice Guidelines for Parenteral Nutrition (1997). Safe practices for parenteral nutrition formulations. J Parenter Enteral Nutr 22, 49-66.
16. Orzalesi M (1987). Vitamins and the premature. Biol Neonate 52 (Suppl 1), 97-112.
17. Perrone S, Salvi G, Bellieni CV, Buonocore G (2007). Oxidative stress and nutrition in the preterm newborn. J Pediatr Gastroenterol Nutr 45, S178-S182.
18. Petrich C, Voss HV, Lietke K, Gobel U (1976). Vitamin E concentrations in term and preterm newborns and their clinical course. Eur J Pediatr 122, 275-279.
19. Salsbury DC (2001). Anemia of prematurity. Neonatal Netw 20, 13-20.
20. Saugstad OD (1996). Mechanism of tissue injury by oxygen radicals: implications for neonatal disease. Acta Pediatr 85, 1-4.
21. Saugstad OD (2001). Update of oxygen radical disease in neonatology. Curr Opin Obstet Gynecol 13, 147-153.
22. Sharda B (2006). Free radicals: emerging challenge in environmental health research in childhood and neonatal disorders. Int J Environ Res Public Health 3, 286-291.
23. Skouroliakou M, Konstantinou D, Papasarantopoulos P, Matthaiou C (2005). Computer assisted total parenteral nutrition for pre-term and sick term neonates. Pharm World Sci 27, 305-310.
24. Thibeault DW (2000). The precarious antioxidant defenses of the preterm infant. Am J Perinat 17, 167-181.
25. Tyson JE, Wright LL, Oh W, Kennedy KA, Mele L, Ehrenkranz RA et al. (1999). Vitamin A supplementation for extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network. N Engl J Med 340, 1962-1968.
26. Uauy R, Hoffman DR (2000). Essential fat requirements of preterm infants. Am J Clin Nutr 71, 245S-250S.
27. Valentine CJ, Puthoff TD (2007). Enhancing parenteral nutrition therapy for neonates. Nutr Clin Pract 22, 183-193.
28. Yeung MY (2006). Influence of early postnatal nutritional management on oxidative stress and antioxidant defense in extreme prematurity. Acta Pediatr 95, 153-163.