First synthesis and full characterization of mexiletine N-carbonyloxy β-d-glucuronide

Tetrahedron Letters

Volumn 51, Issue 40, 2010, Pages 5265-5268

  Cavalluzzi, Maria Maddalena ^a   Lentini, Giovanni ^a   Lovece, Angelo ^a   Bruno, Claudio ^a   Catalano, Alessia ^a   Carocci, Alessia ^a   Franchini, Carlo ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Curtius rearrangement; Glycosidic linkage; Ring opening reaction; Stereochemistry

Indexed keywords

MEXILETINE; MEXILETINE N CARBONYLOXY BETA DEXTRO GLUCURONIDE; SODIUM; UNCLASSIFIED DRUG;

ANALYTICAL RESEARCH; ARTICLE; DRUG ACTIVITY; DRUG METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 77956338816     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.07.150     Document Type: Article

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43. Compound 4 may be also referred to as methyl 5-[2-(2,6-dimethylphenoxy) -1- methylethylaminocarbonyloxy]-2,3,4-tri-O-acetyl-β-d-glucopyranuronate.
44. Compound 1·Na may be also referred to as sodium 5-[2-(2,6-dimethylphenoxy)-1-methylethylaminocarbonyloxy]-β-d- glucopyranuronate.