Deep sequencing of target linkage assay-identified regions in familial breast cancer: Methods, analysis pipeline and troubleshooting

PLoS ONE

Volumn 5, Issue 4, 2010, Pages

  Rosa Rosa, Juan Manuel ^a   Gracia Aznárez, Francisco Javier ^a   Hodges, Emily ^b   Pita, Guillermo ^a   Rooks, Michelle ^b   Xuan, Zhenyu ^c   Bhattacharjee, Arindam ^d   Brizuela, Leonardo ^d   Silva, José M ^e   Hannon, Gregory J ^b   Benitez, Javier ^a  

^a Structural Biology and Biocomputing Programme   (Spain)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

^d AGILENT TECHNOLOGIES   (United States)

^e Department of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; CHROMOSOME 3; CHROMOSOME 6; CLINICAL ARTICLE; CONTROLLED STUDY; DEEP SEQUENCING OF TARGET LINKAGE ASSAY; FAMILIAL CANCER; GENE LOCATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HIGH THROUGHPUT SCREENING; HUMAN; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; ONCOGENE; PENETRANCE; BREAST TUMOR; DNA SEQUENCE; FAMILY HEALTH; FEMALE; GENETIC PREDISPOSITION; GENETICS; METHODOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 6; FAMILY HEALTH; FEMALE; GENETIC LINKAGE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; PENETRANCE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 77956323966     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009976     Document Type: Article

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