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Volumn 135, Issue 4, 2010, Pages 302-306

The Optimult study concept - Selective neoadjuvant chemoradiation therapy based on preoperative MRI?;Das optimult-studienkonzept - Grundlage für selektiven einsatz neoadjuvanter radiochemotherapie auf MRT-basis?

Author keywords

local recurrence of tumour growth; quality of life; rectal carcinoma cancer

Indexed keywords

ADJUVANT THERAPY; ARTICLE; CANCER INVASION; CANCER STAGING; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; GERMANY; HUMAN; MULTICENTER STUDY; MULTIMODALITY CANCER THERAPY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATIENT SELECTION; POSTOPERATIVE COMPLICATION; PRACTICE GUIDELINE; PROGNOSIS; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RECTUM; RECTUM TUMOR; REOPERATION; TREATMENT OUTCOME; TUMOR RECURRENCE;

EID: 77956316530     PISSN: 0044409X     EISSN: 14389592     Source Type: Journal    
DOI: 10.1055/s-0030-1262523     Document Type: Article
Times cited : (3)

References (40)
  • 1
    • 0029805711 scopus 로고    scopus 로고
    • Designing the optimal surgery for rectal carcinoma
    • Enker W E. Designing the optimal surgery for rectal carcinoma. Cancer 1996 78 1847-1850
    • (1996) Cancer , vol.78 , pp. 1847-1850
    • Enker, W.E.1
  • 2
    • 33748789596 scopus 로고    scopus 로고
    • Rektumkarzinom: Behandeln wir zu häufig neoadjuvant? Vorschläge zu einer selektiveren, MRT-basierten Indikation
    • Junginger T, Hermanek P, Oberholzer K et al. Rektumkarzinom: Behandeln wir zu häufig neoadjuvant? Vorschläge zu einer selektiveren, MRT-basierten Indikation. Zentralbl Chir 2006 131 275-284
    • (2006) Zentralbl Chir , vol.131 , pp. 275-284
    • Junginger, T.1    Hermanek, P.2    Oberholzer, K.3
  • 3
    • 0032886355 scopus 로고    scopus 로고
    • Local recurrence after curative excision of the rectum for cancer without adjuvant therapy: Role of total anatomic dissection
    • Bokey E L., Öjerskog B, Chapuis P H. et al. Local recurrence after curative excision of the rectum for cancer without adjuvant therapy: role of total anatomic dissection. Br J Surg 1999 86 1164-1170
    • (1999) Br J Surg , vol.86 , pp. 1164-1170
    • Bokey, E.L.1    Öjerskog, B.2    Chapuis, P.H.3
  • 4
    • 0019977792 scopus 로고
    • The mesorectum in rectal cancer surgery the clue to pelvic recurrence?
    • Heald R J., Husband E M., Ryall R D. The mesorectum in rectal cancer surgery the clue to pelvic recurrence? Br J Surg 1982 69 613-616
    • (1982) Br J Surg , vol.69 , pp. 613-616
    • Heald, R.J.1    Husband, E.M.2    Ryall, R.D.3
  • 5
    • 61349188341 scopus 로고    scopus 로고
    • Preoperative radiotherapy versus slelective posopterative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): A multicentre, randomized trial
    • Sebag-Montefiore D, Stephens R J., Steele R et al. Preoperative radiotherapy versus slelective posopterative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomized trial. Lancet 2009 373 811-820
    • (2009) Lancet , vol.373 , pp. 811-820
    • Sebag-Montefiore, D.1    Stephens, R.J.2    Steele, R.3
  • 6
    • 0035975394 scopus 로고    scopus 로고
    • Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer
    • Kapiteijn E, Marijnen C A., Nagtegaal I D. et al. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 2001 345 638-646
    • (2001) N Engl J Med , vol.345 , pp. 638-646
    • Kapiteijn, E.1    Marijnen, C.A.2    Nagtegaal, I.D.3
  • 7
    • 6044226542 scopus 로고    scopus 로고
    • Preoperative versus postoperative chemoradiotherapy for rectal cancer
    • German Rectal Cancer Study Group
    • Sauer R, Becker H, Hohenberger W, et al., German Rectal Cancer Study Group. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004 351 1731-1740
    • (2004) N Engl J Med , vol.351 , pp. 1731-1740
    • Sauer, R.1    Becker, H.2    Hohenberger, W.3
  • 8
    • 77951707669 scopus 로고    scopus 로고
    • Preoperative or postoperative therapy for stageII or III rectal cancer: An update practice guideline
    • Gastrointestinal Cancer Disease Site Group (2010)
    • Wong R K., Berry S, Spithoff K, et al., Gastrointestinal Cancer Disease Site Group (2010). Preoperative or postoperative therapy for stageII or III rectal cancer: an update practice guideline. Clin Oncol (R Coll Radiol) 2010 22 265-271
    • (2010) Clin Oncol (R Coll Radiol) , vol.22 , pp. 265-271
    • Wong, R.K.1    Berry, S.2    Spithoff, K.3
  • 9
    • 0036190416 scopus 로고    scopus 로고
    • Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma
    • Nagtegaal I D., Marijnen C AM, Kranenberg E K. et al. Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma. Am J Surg Pathol 2002 26 350-357
    • (2002) Am J Surg Pathol , vol.26 , pp. 350-357
    • Nagtegaal, I.D.1    Marijnen, C.A.2    Kranenberg, E.K.3
  • 10
    • 0036484683 scopus 로고    scopus 로고
    • T4 rectal carcinoma. Surgical and multimodal therapy
    • Rau B, Hohenberger P, Gellermann J et al. T4 rectal carcinoma. Surgical and multimodal therapy. Chirurg 2002 73 147-153
    • (2002) Chirurg , vol.73 , pp. 147-153
    • Rau, B.1    Hohenberger, P.2    Gellermann, J.3
  • 11
    • 3242716904 scopus 로고    scopus 로고
    • Sphincter preservation following preoperative radiotherapy for rectal cancer: Report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy
    • Bujko K, Nowacki M P., Nasierowska-Guttmejer A et al. Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy. Radiother Oncol 2004 72 15-24
    • (2004) Radiother Oncol , vol.72 , pp. 15-24
    • Bujko, K.1    Nowacki, M.P.2    Nasierowska-Guttmejer, A.3
  • 12
    • 33747270013 scopus 로고    scopus 로고
    • Does rectal cancer shrinkage induced by preoperative radio(chemo)therapy increase the likelihood of anterior resection? A systematic review of randomised trials
    • Buijko K, Kepka L, Michalski W et al. Does rectal cancer shrinkage induced by preoperative radio(chemo)therapy increase the likelihood of anterior resection? A systematic review of randomised trials. Radiother Oncol 2006 80 4-12
    • (2006) Radiother Oncol , vol.80 , pp. 4-12
    • Buijko, K.1    Kepka, L.2    Michalski, W.3
  • 13
    • 0034771788 scopus 로고    scopus 로고
    • Total mesorectal excision preserves male genital function compared with conventional rectal cancer surgery
    • Maurer C A., ZGraggen K, Renzulli P et al. Total mesorectal excision preserves male genital function compared with conventional rectal cancer surgery. Br J Surg 2001 88 1501-1505
    • (2001) Br J Surg , vol.88 , pp. 1501-1505
    • Maurer, C.A.1    Zgraggen, K.2    Renzulli, P.3
  • 14
    • 24944581750 scopus 로고    scopus 로고
    • Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: Increased bowel dysfunction in irradiated patients a Dutch colorectal cancer group study
    • Peeters K C., van de Velde C J., Leer J W. et al. Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: increased bowel dysfunction in irradiated patients a Dutch colorectal cancer group study. J Clin Oncol 2005 23 6199-6206
    • (2005) J Clin Oncol , vol.23 , pp. 6199-6206
    • Peeters, K.C.1    Van De Velde, C.J.2    Leer, J.W.3
  • 15
    • 33644985510 scopus 로고    scopus 로고
    • Long-term effect of preoperative radiation therapy on anorectal function
    • Pollack J, Holm T, Cedermark B et al. Long-term effect of preoperative radiation therapy on anorectal function. Dis Colon Rectum 2006 49 345-352
    • (2006) Dis Colon Rectum , vol.49 , pp. 345-352
    • Pollack, J.1    Holm, T.2    Cedermark, B.3
  • 16
    • 17744389182 scopus 로고    scopus 로고
    • Quantitative short-term study of anal sphincter function after chemoradiation for rectal cancer
    • Gervaz P, Rotholtz N, Pisano M et al. Quantitative short-term study of anal sphincter function after chemoradiation for rectal cancer. Arch Surg 2001 136 192-196
    • (2001) Arch Surg , vol.136 , pp. 192-196
    • Gervaz, P.1    Rotholtz, N.2    Pisano, M.3
  • 17
    • 0037337403 scopus 로고    scopus 로고
    • Impact of neoadjuvant chemoradiation on anal sphincter function in patients with carcinoma of the midrectum and low rectum
    • Ammann K, Kirchmayr W, Klaus A et al. Impact of neoadjuvant chemoradiation on anal sphincter function in patients with carcinoma of the midrectum and low rectum. Arch Surg 2003 138 257-261
    • (2003) Arch Surg , vol.138 , pp. 257-261
    • Ammann, K.1    Kirchmayr, W.2    Klaus, A.3
  • 18
    • 77951884382 scopus 로고    scopus 로고
    • The short-term effect of neoadjuvant chemoradiation on anorectal function in low and midrectal cancer: Analysis using preoperative manometric data
    • Jang N Y., Han T J., Kang S B. et al. The short-term effect of neoadjuvant chemoradiation on anorectal function in low and midrectal cancer: analysis using preoperative manometric data. Dis Colon Rectum 2010 53 445-449
    • (2010) Dis Colon Rectum , vol.53 , pp. 445-449
    • Jang, N.Y.1    Han, T.J.2    Kang, S.B.3
  • 19
    • 34548384419 scopus 로고    scopus 로고
    • Quality of life, anorectal and sexual functions after preoperative radiotherapy for rectal cancer: Report of a randomised trial
    • Pietrzak L, Bujko K, Nowacki M P. et al. Quality of life, anorectal and sexual functions after preoperative radiotherapy for rectal cancer: report of a randomised trial. Radiother Oncol 2007 84 217-225
    • (2007) Radiother Oncol , vol.84 , pp. 217-225
    • Pietrzak, L.1    Bujko, K.2    Nowacki, M.P.3
  • 20
    • 34648835179 scopus 로고    scopus 로고
    • Effect of neoadjuvant chemoradiation on postoperative fecal continence and anal sphincter function in rectal cancer patients
    • Pietsch A P., Fietkau R, Klautke G et al. Effect of neoadjuvant chemoradiation on postoperative fecal continence and anal sphincter function in rectal cancer patients. Int J Colorectal Dis 2007 22 1311-1317
    • (2007) Int J Colorectal Dis , vol.22 , pp. 1311-1317
    • Pietsch, A.P.1    Fietkau, R.2    Klautke, G.3
  • 21
    • 0036204946 scopus 로고    scopus 로고
    • Rates of circumferential resection margin involvement vary between surgeons and predict outcomes in rectal cancer surgery
    • Birbeck K F., Macklin C P., Tiffin N J. et al. Rates of circumferential resection margin involvement vary between surgeons and predict outcomes in rectal cancer surgery. Ann Surg 2002 35 449-457
    • (2002) Ann Surg , vol.35 , pp. 449-457
    • Birbeck, K.F.1    MacKlin, C.P.2    Tiffin, N.J.3
  • 22
    • 34250209521 scopus 로고    scopus 로고
    • Qualitätsindikatoren bei Diagnostik und Therapie des Rektumkarzinoms
    • (Arbeitsgruppe Workflow RektumkarzinomII)
    • Bittner R, Burghardt J, Gross E et al., (Arbeitsgruppe Workflow RektumkarzinomII). Qualitätsindikatoren bei Diagnostik und Therapie des Rektumkarzinoms. Zentralbl Chir 2007 132 85-94
    • (2007) Zentralbl Chir , vol.132 , pp. 85-94
    • Bittner, R.1    Burghardt, J.2    Gross, E.3
  • 23
    • 33747874014 scopus 로고    scopus 로고
    • Alternative clinical end points in rectal cancer are we getting closer?
    • Glynne-Jones R, Mawdsley S, Pearce T et al. Alternative clinical end points in rectal cancer are we getting closer? Ann Oncol 2006 17 1239-1242
    • (2006) Ann Oncol , vol.17 , pp. 1239-1242
    • Glynne-Jones, R.1    Mawdsley, S.2    Pearce, T.3
  • 24
    • 25844507873 scopus 로고    scopus 로고
    • Can histopathologic assessment of circumferential margin after preoperative pelvic clearance therapy for T3T4 rectal cancer predict for 3-year disease-free survival?
    • Mawdsley S, Glynne-Jones R, Grainger J et al. Can histopathologic assessment of circumferential margin after preoperative pelvic clearance therapy for T3T4 rectal cancer predict for 3-year disease-free survival? Int J Radiat Oncol Biol Phys 2005 63 745-750
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 745-750
    • Mawdsley, S.1    Glynne-Jones, R.2    Grainger, J.3
  • 25
    • 54049129221 scopus 로고    scopus 로고
    • Magnetic resonance imaging (MRI)-based indication for neoadjuvant treatment of rectal carcinoma and the surrogate endpoint CRM status
    • Strassburg J, Junginger T, Trinh T et al. Magnetic resonance imaging (MRI)-based indication for neoadjuvant treatment of rectal carcinoma and the surrogate endpoint CRM status. Int J Colorect Dis 2008 23 1099-1107
    • (2008) Int J Colorect Dis , vol.23 , pp. 1099-1107
    • Strassburg, J.1    Junginger, T.2    Trinh, T.3
  • 26
    • 33846869995 scopus 로고    scopus 로고
    • Prognostic groups in 1676patients with T3 rectal cancer treated without preoperative radiotherapy
    • Norwegian Rectal Cancer Group
    • Eriksen M T., Wibe A, Haffner J, et al., Norwegian Rectal Cancer Group. Prognostic groups in 1676patients with T3 rectal cancer treated without preoperative radiotherapy. Dis Colon Rectum 2007 50 156-167
    • (2007) Dis Colon Rectum , vol.50 , pp. 156-167
    • Eriksen, M.T.1    Wibe, A.2    Haffner, J.3
  • 27
    • 0036190416 scopus 로고    scopus 로고
    • Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma
    • Nagtegaal I D., Marijnen C AM, Kranenberg E K. et al. Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma. Am J Surg Pathol 2002 26 350-357
    • (2002) Am J Surg Pathol , vol.26 , pp. 350-357
    • Nagtegaal, I.D.1    Marijnen, C.A.2    Kranenberg, E.K.3
  • 28
    • 38349107307 scopus 로고    scopus 로고
    • What is the role of the circumferential margin in the modern treatment of rectal cancer
    • Nagtegaal I D., Quirke P. What is the role of the circumferential margin in the modern treatment of rectal cancer. J Clin Oncol 2008 26 303-312
    • (2008) J Clin Oncol , vol.26 , pp. 303-312
    • Nagtegaal, I.D.1    Quirke, P.2
  • 29
    • 34249055553 scopus 로고    scopus 로고
    • Combinations of tumor and treatment parameters are more discriminative for prognosis than the present TNM system in rectal cancer
    • Nagtegaal I D., Gosens M J., Marijnen C A. et al. Combinations of tumor and treatment parameters are more discriminative for prognosis than the present TNM system in rectal cancer. J Clin Oncol 2007 25 1647-1650
    • (2007) J Clin Oncol , vol.25 , pp. 1647-1650
    • Nagtegaal, I.D.1    Gosens, M.J.2    Marijnen, C.A.3
  • 30
    • 3242808840 scopus 로고    scopus 로고
    • Rectal cancer: Review with emphasis on MR imaging
    • Beets-Tan R GH, Beets G L. Rectal cancer: Review with emphasis on MR imaging. Radiol 2004 232 335-346
    • (2004) Radiol , vol.232 , pp. 335-346
    • Beets-Tan, R.G.1    Beets, G.L.2
  • 31
    • 0032960599 scopus 로고    scopus 로고
    • Rectal carcinoma: Thin-section MR imaging for staging in 28patients
    • Brown G, Richards C J., Newcombe R G. et al. Rectal carcinoma: thin-section MR imaging for staging in 28patients. Radiology 1999 211 215-222
    • (1999) Radiology , vol.211 , pp. 215-222
    • Brown, G.1    Richards, C.J.2    Newcombe, R.G.3
  • 32
    • 33750071992 scopus 로고    scopus 로고
    • Diagnostic accuracy of preoperative magnetic resonance imaging in predictiong curative resection of rectal cancer: Prospective observational study
    • MERCURY Study Group
    • MERCURY Study Group. Diagnostic accuracy of preoperative magnetic resonance imaging in predictiong curative resection of rectal cancer: prospective observational study. Br Med J 2006 333 779-784
    • (2006) Br Med J , vol.333 , pp. 779-784
  • 33
    • 33847304368 scopus 로고    scopus 로고
    • High-resolution magnetic resonance imaging (MRI) in patients with rectal carcinoma: Effectiveness in selection for neoadjuvant treatment
    • Hermanek P, Junginger T, Merkel S et al. High-resolution magnetic resonance imaging (MRI) in patients with rectal carcinoma: Effectiveness in selection for neoadjuvant treatment. Recent Res Devel Cancer 2006 8 39-56
    • (2006) Recent Res Devel Cancer , vol.8 , pp. 39-56
    • Hermanek, P.1    Junginger, T.2    Merkel, S.3
  • 34
    • 0038639917 scopus 로고    scopus 로고
    • Perioperative radiotherapy for rectal cancer: The case for a selective pre-operative approach the third way
    • Crawshaw A, Hennigan R, Smedley F H. et al. Perioperative radiotherapy for rectal cancer: the case for a selective pre-operative approach the third way. Colorectal Dis 2003 5 367-372
    • (2003) Colorectal Dis , vol.5 , pp. 367-372
    • Crawshaw, A.1    Hennigan, R.2    Smedley, F.H.3
  • 35
    • 32544450679 scopus 로고    scopus 로고
    • MRI directed multidisciplinary team preoperative treatment strategy: The way to eliminate positive circumferential margins?
    • on behalf of the Royal Marsden Hospital, Colorectal Cancer Network
    • Burton S, Brown G, Daniels I R., et al. on behalf of the Royal Marsden Hospital, Colorectal Cancer Network. MRI directed multidisciplinary team preoperative treatment strategy: the way to eliminate positive circumferential margins? Br J Cancer 2006 94 351-357
    • (2006) Br J Cancer , vol.94 , pp. 351-357
    • Burton, S.1    Brown, G.2    Daniels, I.R.3
  • 36
    • 33644846344 scopus 로고    scopus 로고
    • Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer
    • Chau I, Brown G, Cunningham D et al. Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer. J Clin Oncol 2006 24 668-674
    • (2006) J Clin Oncol , vol.24 , pp. 668-674
    • Chau, I.1    Brown, G.2    Cunningham, D.3
  • 37
    • 77649235151 scopus 로고    scopus 로고
    • Tailored treatment of primary rectal cancer based on MRI: Does it reduce the number of incomplete resections? Abstract
    • Engelen S, Lahaye M J., Beets-Tan R G. et al. Tailored treatment of primary rectal cancer based on MRI: does it reduce the number of incomplete resections? Abstract. Ann Oncol 2008 19 Suppl1 1-17
    • (2008) Ann Oncol , vol.19 , Issue.SUPPL. 1 , pp. 1-17
    • Engelen, S.1    Lahaye, M.J.2    Beets-Tan, R.G.3
  • 38
    • 18444388842 scopus 로고    scopus 로고
    • Preoperative staging of rectal cancer: The MERCURY research project
    • Brown G, Daniels I R. Preoperative staging of rectal cancer: the MERCURY research project. Recent Results Cancer Research 2005 165 58-74
    • (2005) Recent Results Cancer Research , vol.165 , pp. 58-74
    • Brown, G.1    Daniels, I.R.2
  • 40
    • 77955198063 scopus 로고    scopus 로고
    • Individualized MRI-based neoadjuvant chemoradiation for middle and lower rectal carcinoma
    • Epub ahead of print
    • Hermanek P, Hohenberger W, Fietkau R et al. Individualized MRI-based neoadjuvant chemoradiation for middle and lower rectal carcinoma. Colorectal Dis 2009 [Epub ahead of print]
    • (2009) Colorectal Dis
    • Hermanek, P.1    Hohenberger, W.2    Fietkau, R.3


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