Age- and gender-specific association between ADA (22G>A) and TNF-α (-308G>A) genetic polymorphisms

Tissue Antigens

Volumn 76, Issue 4, 2010, Pages 311-314

  Napolioni, V ^a   Predazzi, I M ^b  

^a UNIVERSITY OF CAMERINO   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

adenosine deaminase; gene gene interaction; genetic polymorphism; tumor necrosis factor; tumor necrosis factor alpha

Indexed keywords

ADENOSINE DEAMINASE; ALANINE; GLYCINE; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; AGE DISTRIBUTION; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HEART DISEASE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SCHOOL CHILD; SEX DIFFERENCE;

ADENOSINE DEAMINASE; ADULT; AGE FACTORS; AGED; FEMALE; HUMANS; ITALY; LINEAR MODELS; MALE; POLYMORPHISM, GENETIC; SEX FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77956298345     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2010.01510.x     Document Type: Article

References (21)

1. Vassalli P. The pathophysiology of tumor necrosis factor. Annu Rev Immunol 1992 : 10 : 411 452.
2. Bayley JP, Ottenhoff TH, Verweij CL. Is there a future for TNF promoter polymorphisms? Genes Immun 2004 : 5 : 315 329.
3. Elahi MM, Asotra K, Matata BM, Mastana SS. Tumor necrosis factor alpha -308 gene locus promoter polymorphism: an analysis of association with health and disease. Biochim Biophys Acta 2009 : 1792 : 163 172.
4. Da Silva GJ, Moreira ED, Pereira AC et al. Ace gene dosage modulates pressure-induced cardiac hypertrophy in mice and men. Physiol Genomics 2006 : 27 : 237 244.
5. Battistuzzi G, Iudicone P, Santolamazza P, Petrucci R. Activity of adenosine deaminase allelic forms in intact erythrocytes and in lymphocytes. Ann Hum Genet 1981 : 45 : 15 9.
6. Eigler A, Greten TF, Sinha B, Haslberger C, Sullivan GW, Endres S. Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis. Scand J Immunol 1997 : 45 : 132 139.
7. Cronstein BN, Naime D, Firestein G. The anti-inflammatory effects of an adenosine kinase inhibitor are mediated by adenosine. Arthritis Rheum 1995 : 38 : 1040 1045.
8. Levy O, Coughlin M, Cronstein BN, Roy RM, Desai A, Wessels MR. The adenosine system selectively inhibits TLR-mediated TNF-a production in the human newborn. J Immunol 2006 : 177 : 1956 1966.
9. Safranow K, Rzeuski R, Binczak-Kuleta A et al. ADA*2 allele of the adenosine deaminase gene may protect against coronary artery disease. Cardiology 2007 : 108 : 275 281.
10. Fargion S, Valenti L, Dongiovanni P et al. Tumor necrosis factor alpha promoter polymorphisms influence the phenotypic expression of hereditary hemochromatosis. Blood 2001 : 97 : 3707 3712.
11. Scozzari R, Santolamazza C, Carapella E. Studies on the red cell adenosine deaminase polymorphism in Rome. Humangenetik 1970 : 8 : 364 365.
12. Mamolini E, Beretta M, Barale R, Rodriguez-Larralde A, Scapoli C, Barrai I. Detection of genetic structures at short distances in the Pisa area. Hum Hered 1998 : 48 : 12 23.
13. Uboldi de Capei MU, Dametto E, Fasano ME, Rendine S, Curtoni ES. Genotyping for cytokine polymorphisms: allele frequencies in the Italian population. Eur J Immunogenet 2003 : 30 : 5 10.
14. Friedrichs F, Brescianini S, Annese V et al. Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men. Hum Genet 2006 : 119 : 305 311.
15. Bottini E, Carapella E, Cataldi L et al. Adenosine deaminase polymorphism. Associations at clinical level suggest a role in cell functions and immune reactions. J Med Genet 1981 : 18 : 331 334.
16. Angele MK, Schwacha MG, Ayala A, Chaudry IH. Effect of gender and sex hormones on immune responses following shock. Shock 2000 : 14 : 81 90.
17. Banci M, Saccucci P, D'Annibale F et al. Adenosine deaminase genetic polymorphism and coronary artery disease. Cardiology 2009 : 112 : 74 5.
18. Huxley VH, Wang JJ, Whitt SP. Sexual dimorphism in the permeability response of coronary microvessels to adenosine. Am J Physiol Heart Circ Physiol 2005 : 288 : 2006 2013.
19. Temple SE, Pham K, Glendenning P, Phillips M, Waterer GW. Endotoxin induced TNF and IL-10 mRNA production is higher in male than female donors: correlation with elevated expression of TLR4. Cell Immunol 2008 : 251 : 69 71.
20. Knoferl MW, Angele MK, Diodato MD et al. Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis. Ann Surg 2002 : 235 : 105 112.
21. Wang M, Tsai BM, Kher A, Baker LB, Wairiuko GM, Meldrum DR. Role of endogenous testosterone in myocardial proinflammatory and proapoptotic signaling after acute ischemia-reperfusion. Am J Physiol Heart Circ Physiol 2005 : 288 : 221 226.