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Volumn 12, Issue 4, 2010, Pages 291-298

Approach to the diagnosis and management of tuberculous meningitis

Author keywords

Corticosteroid therapy; Extrapulmonary tuberculosis; Hydrocephalus; Mycobacterium tuberculosis; Polymerase chain reaction; Tuberculous meningitis

Indexed keywords

AMIKACIN; ANTIINFECTIVE AGENT; CORTICOSTEROID; CORTICOTROPIN; CORTISONE; CYCLOSERINE; DEXAMETHASONE; ETHAMBUTOL; ETHIONAMIDE; HYDROCORTISONE; ISONIAZID; KANAMYCIN; MOXIFLOXACIN; PREDNISOLONE; PREDNISONE; PYRAZINAMIDE; PYRIDOXINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFABUTIN; RIFAMPICIN; STREPTOMYCIN;

EID: 77956267095     PISSN: 15233847     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11908-010-0106-3     Document Type: Review
Times cited : (8)

References (50)
  • 1
    • 33645777981 scopus 로고    scopus 로고
    • Tuberculosis
    • edn 3. Edited by Scheld WM, Whitley RJ, Marra CM. Philadelphia: Lippincott Williams & Wilkins
    • Zuger A: Tuberculosis. In Infections of the Central Nervous System, edn 3. Edited by Scheld WM, Whitley RJ, Marra CM. Philadelphia: Lippincott Williams & Wilkins; 2004:441-460.
    • (2004) In Infections of the Central Nervous System , pp. 441-460
    • Zuger, A.1
  • 2
    • 0011367598 scopus 로고    scopus 로고
    • Lippincott Williams & Wilkins Philadelphia
    • Tunkel AR: Bacterial Meningitis. Philadelphia: Lippincott Williams & Wilkins; 2001.
    • (2001) Bacterial Meningitis
    • Tunkel, A.R.1
  • 4
    • 0034548037 scopus 로고    scopus 로고
    • The clinical, radiological and pathological profile of tuberculous meningitis in patients with and without human immunodeficiency virus infection
    • 10.1016/S0022-510X(00)00440-8 1:STN:280:DC%2BD3M%2FpvVaqsw%3D%3D 11099721
    • SM Katrak PK Shembalkar SR Bijwe LD Bhandarkar 2000 The clinical, radiological and pathological profile of tuberculous meningitis in patients with and without human immunodeficiency virus infection J Neurol Sci 181 118 126 10.1016/S0022-510X(00)00440-8 1:STN:280:DC%2BD3M%2FpvVaqsw%3D%3D 11099721
    • (2000) J Neurol Sci , vol.181 , pp. 118-126
    • Katrak, S.M.1    Shembalkar, P.K.2    Bijwe, S.R.3    Bhandarkar, L.D.4
  • 5
    • 46349105016 scopus 로고    scopus 로고
    • Clinical and microbiological features of HIV-associated tuberculous meningitis in Vietnamese adults
    • 10.1371/journal.pone.0001772 18350135
    • ME Torok TT Chau PP Mai, et al. 2008 Clinical and microbiological features of HIV-associated tuberculous meningitis in Vietnamese adults PLoS ONE 3 e1772 10.1371/journal.pone.0001772 18350135
    • (2008) PLoS ONE , vol.3 , pp. 1772
    • Torok, M.E.1    Chau, T.T.2    Mai, P.P.3
  • 6
    • 0032832666 scopus 로고    scopus 로고
    • Culture positive tuberculous meningitis: Clinical indicators of poor prognosis
    • 10.1016/S0303-8467(99)00025-6 1:STN:280:DC%2BD3c%2FgsFaqsA%3D%3D 10536900
    • EK Tan MWL Chee LL Chan YL Lee 1999 Culture positive tuberculous meningitis: clinical indicators of poor prognosis Clin Neurol Neurosurg 101 157 160 10.1016/S0303-8467(99)00025-6 1:STN:280:DC%2BD3c%2FgsFaqsA%3D%3D 10536900
    • (1999) Clin Neurol Neurosurg , vol.101 , pp. 157-160
    • Tan, E.K.1    Chee, M.W.L.2    Chan, L.L.3    Lee, Y.L.4
  • 7
    • 0032793966 scopus 로고    scopus 로고
    • A diagnostic rule for tuberculous meningitis
    • 10.1136/adc.81.3.221 1:STN:280:DyaK1MvitFGntA%3D%3D 10451394
    • R Kumar SN Singh N Kohli 1999 A diagnostic rule for tuberculous meningitis Arch Dis Child 81 221 224 10.1136/adc.81.3.221 1:STN:280: DyaK1MvitFGntA%3D%3D 10451394
    • (1999) Arch Dis Child , vol.81 , pp. 221-224
    • Kumar, R.1    Singh, S.N.2    Kohli, N.3
  • 8
    • 54049128216 scopus 로고    scopus 로고
    • Predictors of tuberculosis in acute aseptic meningitis syndrome
    • 18767414
    • R Mihailescu A Hristea C Baicus, et al. 2007 Predictors of tuberculosis in acute aseptic meningitis syndrome Rom J Intern Med 45 379 385 18767414
    • (2007) Rom J Intern Med , vol.45 , pp. 379-385
    • Mihailescu, R.1    Hristea, A.2    Baicus, C.3
  • 9
    • 63849291316 scopus 로고    scopus 로고
    • Twenty years of pediatric tuberculous meningitis: A retrospective cohort study in the western cape of South Africa
    • 10.1542/peds.2008-1353 19367678 This paper reports on the largest pediatric cohort of TBM patients (554) yet published. Ethnicity, stage of disease, headache, convulsions, motor function, brainstem dysfunction, and cerebral infarctions were independently associated with poor clinical outcome. Stage II and III disease were very common, as were poor weight gain (or frank weight loss), loss of consciousness, and hydrocephalus. At 6 months, mortality was 13%, and only 16% of children were clinically normal at follow-up
    • GT van Well BF Paes CB Terwee, et al. 2009 Twenty years of pediatric tuberculous meningitis: a retrospective cohort study in the western cape of South Africa Pediatrics 123 e1 e8 10.1542/peds.2008-1353 19367678 This paper reports on the largest pediatric cohort of TBM patients (554) yet published. Ethnicity, stage of disease, headache, convulsions, motor function, brainstem dysfunction, and cerebral infarctions were independently associated with poor clinical outcome. Stage II and III disease were very common, as were poor weight gain (or frank weight loss), loss of consciousness, and hydrocephalus. At 6 months, mortality was 13%, and only 16% of children were clinically normal at follow-up
    • (2009) Pediatrics , vol.123
    • Van Well, G.T.1    Paes, B.F.2    Terwee, C.B.3
  • 10
    • 0036196198 scopus 로고    scopus 로고
    • Predictors of outcome in patients with tuberculous meningitis
    • 1:STN:280:DC%2BD387pvVyitQ%3D%3D
    • S Hosoglu MF Geyik I Balik, et al. 2002 Predictors of outcome in patients with tuberculous meningitis Int J Tubercul Lung Dis 6 64 70 1:STN:280:DC%2BD387pvVyitQ%3D%3D
    • (2002) Int J Tubercul Lung Dis , vol.6 , pp. 64-70
    • Hosoglu, S.1    Geyik, M.F.2    Balik, I.3
  • 11
    • 0042377405 scopus 로고    scopus 로고
    • Clinical relevance of hydrocephalus as a presenting feature of tuberculous meningitis
    • 1:STN:280:DC%2BD3szovVyrug%3D%3D
    • KH Chan RT Cheung CY Fong, et al. 2003 Clinical relevance of hydrocephalus as a presenting feature of tuberculous meningitis Q J Med 96 643 648 1:STN:280:DC%2BD3szovVyrug%3D%3D
    • (2003) Q J Med , vol.96 , pp. 643-648
    • Chan, K.H.1    Cheung, R.T.2    Fong, C.Y.3
  • 12
    • 67649097128 scopus 로고    scopus 로고
    • Predictors of stroke and its significance in the outcome of tuberculous meningitis
    • 10.1016/j.jstrokecerebrovasdis.2008.11.007 19560677
    • J Kalita UK Misra PP Nair 2009 Predictors of stroke and its significance in the outcome of tuberculous meningitis J Stroke Cerebrovasc Dis 18 251 258 10.1016/j.jstrokecerebrovasdis.2008.11.007 19560677
    • (2009) J Stroke Cerebrovasc Dis , vol.18 , pp. 251-258
    • Kalita, J.1    Misra, U.K.2    Nair, P.P.3
  • 13
    • 38349008743 scopus 로고    scopus 로고
    • Chest computerized tomography scan findings in 74 children with tuberculous meningitis in southeastern Turkey
    • 18246736
    • A Yaramis Y Bukte S Katar MN Ozbek 2007 Chest computerized tomography scan findings in 74 children with tuberculous meningitis in southeastern Turkey Turk J Pediatr 49 365 369 18246736
    • (2007) Turk J Pediatr , vol.49 , pp. 365-369
    • Yaramis, A.1    Bukte, Y.2    Katar, S.3    Ozbek, M.N.4
  • 14
    • 67749095837 scopus 로고    scopus 로고
    • MRI to demonstrate diagnostic features and complications of TBM not seen with CT
    • 10.1007/s00381-008-0785-3
    • M Piepaar S Andronikou R van Toorn 2009 MRI to demonstrate diagnostic features and complications of TBM not seen with CT Childs Nerv Syst 25 941 947 10.1007/s00381-008-0785-3
    • (2009) Childs Nerv Syst , vol.25 , pp. 941-947
    • Piepaar, M.1    Andronikou, S.2    Van Toorn, R.3
  • 15
    • 67149094787 scopus 로고    scopus 로고
    • Atypical cerebrospinal fluid profile in tuberculous meningitis
    • 10.1258/td.2008.080242 19299285
    • VL Pinto Jr MA Lima VC Rolla, et al. 2009 Atypical cerebrospinal fluid profile in tuberculous meningitis Trop Doct 39 76 78 10.1258/td.2008.080242 19299285
    • (2009) Trop Doct , vol.39 , pp. 76-78
    • Pinto Jr., V.L.1    Lima, M.A.2    Rolla, V.C.3
  • 16
    • 55949102142 scopus 로고    scopus 로고
    • Temporal evolution of cerebrospinal fluid following initiation of treatment for tuberculous meningitis
    • 1:STN:280:DC%2BD1cnntFektQ%3D%3D 18928039 Prior to this publication, changes in CSF following the initiation of antituberculous treatment had not been well described. The rapid changes in neutrophil count and glucose concentration on repeat CSF samples of 99 patients with TBM seemed to assist clinicians in making decisions about patient care in the early phase of treatment, in contrast to the slow changes in lymphocyte count and protein concentration. It was believed to be very atypical for TBM for a repeat lumbar puncture (at 4-8 weeks) not to show definite improvement in neutrophil count and glucose concentration
    • VB Patel I Burger C Connolly 2008 Temporal evolution of cerebrospinal fluid following initiation of treatment for tuberculous meningitis S Afr Med J 98 610 613 1:STN:280:DC%2BD1cnntFektQ%3D%3D 18928039 Prior to this publication, changes in CSF following the initiation of antituberculous treatment had not been well described. The rapid changes in neutrophil count and glucose concentration on repeat CSF samples of 99 patients with TBM seemed to assist clinicians in making decisions about patient care in the early phase of treatment, in contrast to the slow changes in lymphocyte count and protein concentration. It was believed to be very atypical for TBM for a repeat lumbar puncture (at 4-8 weeks) not to show definite improvement in neutrophil count and glucose concentration
    • (2008) S Afr Med J , vol.98 , pp. 610-613
    • Patel, V.B.1    Burger, I.2    Connolly, C.3
  • 17
    • 34848844127 scopus 로고    scopus 로고
    • Comparative evaluation of BACTEC 460TB system and Lowenstein-Jensen medium for the isolation of M. tuberculosis from cerebrospinal fluid samples of tuberculous meningitis patients
    • 10.4103/0255-0857.34765 1:STN:280:DC%2BD2srnvV2nsw%3D%3D 17901641
    • MM Venkataswamy W Rafi S Nagarathna, et al. 2007 Comparative evaluation of BACTEC 460TB system and Lowenstein-Jensen medium for the isolation of M. tuberculosis from cerebrospinal fluid samples of tuberculous meningitis patients Indian J Med Microbiol 25 236 240 10.4103/0255-0857.34765 1:STN:280: DC%2BD2srnvV2nsw%3D%3D 17901641
    • (2007) Indian J Med Microbiol , vol.25 , pp. 236-240
    • Venkataswamy, M.M.1    Rafi, W.2    Nagarathna, S.3
  • 18
    • 43149117083 scopus 로고    scopus 로고
    • Evaluation of the MODS culture technique for the diagnosis of tuberculous meningitis
    • 10.1371/journal.pone.0001173 18000545 These investigators showed the MODS culture technique to be nearly as sensitive as mycobacterial growth indicator tube (MGIT) and Lowenstein-Jensen (LJ) cultures for the diagnosis of TBM (65% sensitivity for MODS vs 70% sensitivity for the other two methods, using clinical diagnosis as the gold standard). The great advantages to the MODS technique were a mean time to positive culture of 6 days (vs 15.5 days for MGIT and 24 days for LJ cultures), a very low cost per sample (once an inverted microscope is purchased), and the ability to have susceptibility results as soon as cultures are positive
    • M Caws TM Dang E Torok, et al. 2007 Evaluation of the MODS culture technique for the diagnosis of tuberculous meningitis PLoS ONE 2 e1173 10.1371/journal.pone.0001173 18000545 These investigators showed the MODS culture technique to be nearly as sensitive as mycobacterial growth indicator tube (MGIT) and Lowenstein-Jensen (LJ) cultures for the diagnosis of TBM (65% sensitivity for MODS vs 70% sensitivity for the other two methods, using clinical diagnosis as the gold standard). The great advantages to the MODS technique were a mean time to positive culture of 6 days (vs 15.5 days for MGIT and 24 days for LJ cultures), a very low cost per sample (once an inverted microscope is purchased), and the ability to have susceptibility results as soon as cultures are positive
    • (2007) PLoS ONE , vol.2 , pp. 1173
    • Caws, M.1    Dang, T.M.2    Torok, E.3
  • 19
    • 3142628366 scopus 로고    scopus 로고
    • Adenosine deaminase activity in cerebrospinal fluid of HIV-infected patients: Limited value for diagnosis of tuberculous meningitis
    • 10.1007/s10096-004-1110-z 1:CAS:528:DC%2BD2cXks1Kmtbc%3D 15141333
    • I Corral C Quereda E Navas, et al. 2004 Adenosine deaminase activity in cerebrospinal fluid of HIV-infected patients: limited value for diagnosis of tuberculous meningitis Eur J Clin Microbiol Infect Dis 23 471 476 10.1007/s10096-004-1110-z 1:CAS:528:DC%2BD2cXks1Kmtbc%3D 15141333
    • (2004) Eur J Clin Microbiol Infect Dis , vol.23 , pp. 471-476
    • Corral, I.1    Quereda, C.2    Navas, E.3
  • 20
    • 33846876545 scopus 로고    scopus 로고
    • Role of IS6110 uniplex PCR in the diagnosis of tuberculous meningitis: Experience at a tertiary neurocentre
    • 1:STN:280:DC%2BD2s%2FlvFWmtw%3D%3D
    • W Rafi MM Venkataswamy S Nagarathna, et al. 2007 Role of IS6110 uniplex PCR in the diagnosis of tuberculous meningitis: experience at a tertiary neurocentre Int J Tubercul Lung Dis 11 209 214 1:STN:280: DC%2BD2s%2FlvFWmtw%3D%3D
    • (2007) Int J Tubercul Lung Dis , vol.11 , pp. 209-214
    • Rafi, W.1    Venkataswamy, M.M.2    Nagarathna, S.3
  • 21
    • 43249122697 scopus 로고    scopus 로고
    • Novel wide-range quantitative nested real-time PCR assay for Mycobacterium tuberculosis DNA: Clinical application for diagnosis of tuberculous meningitis
    • 10.1128/JCM.02214-07 1:CAS:528:DC%2BD1cXmvV2msbk%3D 18337387 The use of PCR in the diagnosis of TBM has had much promise, but not nearly as much clinical success up to this point. However, advances are constantly being made. This paper describes a new PCR technique that combines the high sensitivity of nested PCR, the accurate quantification of real-time PCR, and a wide detection range for number of copies of DNA in CSF samples. The clinical usefulness of this exciting technique remains to be determined
    • T Takahashi M Tamura Y Asami, et al. 2008 Novel wide-range quantitative nested real-time PCR assay for Mycobacterium tuberculosis DNA: clinical application for diagnosis of tuberculous meningitis J Clin Microbiol 46 1698 1707 10.1128/JCM.02214-07 1:CAS:528:DC%2BD1cXmvV2msbk%3D 18337387 The use of PCR in the diagnosis of TBM has had much promise, but not nearly as much clinical success up to this point. However, advances are constantly being made. This paper describes a new PCR technique that combines the high sensitivity of nested PCR, the accurate quantification of real-time PCR, and a wide detection range for number of copies of DNA in CSF samples. The clinical usefulness of this exciting technique remains to be determined
    • (2008) J Clin Microbiol , vol.46 , pp. 1698-1707
    • Takahashi, T.1    Tamura, M.2    Asami, Y.3
  • 22
    • 67649227424 scopus 로고    scopus 로고
    • RpoB nested PCR and sequencing for the early diagnosis of tuberculous meningitis and rifampicin resistance
    • HJ Huang DR Xiang JF Sheng, et al. 2009 rpoB nested PCR and sequencing for the early diagnosis of tuberculous meningitis and rifampicin resistance Int J Tubercul Lung Dis 13 749 754
    • (2009) Int J Tubercul Lung Dis , vol.13 , pp. 749-754
    • Huang, H.J.1    Xiang, D.R.2    Sheng, J.F.3
  • 23
    • 67650473256 scopus 로고    scopus 로고
    • Efficient diagnosis of tuberculous meningitis by detection of Mycobacterium tuberculosis DNA in cerebrospinal fluid filtrates using PCR
    • 10.1099/jmm.0.006015-0 1:CAS:528:DC%2BD1MXmt1WksL8%3D 19369523
    • S Haldar N Sharma VK Gupta JS Tyagi 2009 Efficient diagnosis of tuberculous meningitis by detection of Mycobacterium tuberculosis DNA in cerebrospinal fluid filtrates using PCR J Med Microbiol 58 Pt 5 616 624 10.1099/jmm.0.006015-0 1:CAS:528:DC%2BD1MXmt1WksL8%3D 19369523
    • (2009) J Med Microbiol , vol.58 , Issue.PART 5 , pp. 616-624
    • Haldar, S.1    Sharma, N.2    Gupta, V.K.3    Tyagi, J.S.4
  • 24
    • 1542618437 scopus 로고    scopus 로고
    • Comparison of conventional bacteriology with nucleic acid amplification (amplified mycobacterium direct test) for diagnosis of tuberculous meningitis before and after inception of antituberculosis chemotherapy
    • 10.1128/JCM.42.3.996-1002.2004 1:CAS:528:DC%2BD2cXivF2ksLo%3D 15004044
    • GE Thwaites M Caws TT Chau, et al. 2004 Comparison of conventional bacteriology with nucleic acid amplification (amplified mycobacterium direct test) for diagnosis of tuberculous meningitis before and after inception of antituberculosis chemotherapy J Clin Microbiol 42 996 1002 10.1128/JCM.42.3.996- 1002.2004 1:CAS:528:DC%2BD2cXivF2ksLo%3D 15004044
    • (2004) J Clin Microbiol , vol.42 , pp. 996-1002
    • Thwaites, G.E.1    Caws, M.2    Chau, T.T.3
  • 25
    • 0036721259 scopus 로고    scopus 로고
    • Detection of antibody to Mycobacterium tuberculosis protein antigens in the cerebrospinal fluid of patients with tuberculous meningitis
    • 10.1086/342293 1:CAS:528:DC%2BD38XnsVSlurw%3D 12195355
    • A Chandramuki K Lyashchenko HB Kumari, et al. 2002 Detection of antibody to Mycobacterium tuberculosis protein antigens in the cerebrospinal fluid of patients with tuberculous meningitis J Infect Dis 186 678 683 10.1086/342293 1:CAS:528:DC%2BD38XnsVSlurw%3D 12195355
    • (2002) J Infect Dis , vol.186 , pp. 678-683
    • Chandramuki, A.1    Lyashchenko, K.2    Kumari, H.B.3
  • 26
    • 0036280290 scopus 로고    scopus 로고
    • The application of the Mancini technique as a diagnostic test in the CSF of tuberculous meningitis patients
    • 12070446
    • RS Kashyap NP Agarwal NH Chandak, et al. 2002 The application of the Mancini technique as a diagnostic test in the CSF of tuberculous meningitis patients Med Sci Monit 8 MT95 MT98 12070446
    • (2002) Med Sci Monit , vol.8
    • Kashyap, R.S.1    Agarwal, N.P.2    Chandak, N.H.3
  • 27
    • 1642565246 scopus 로고    scopus 로고
    • Rapid diagnosis of tuberculous meningitis using the Simple Dot ELISA method
    • 14586287
    • RS Kashyap RP Kainthla SK Biswas, et al. 2003 Rapid diagnosis of tuberculous meningitis using the Simple Dot ELISA method Med Sci Monit 9 MT123 MT126 14586287
    • (2003) Med Sci Monit , vol.9
    • Kashyap, R.S.1    Kainthla, R.P.2    Biswas, S.K.3
  • 28
    • 0041302460 scopus 로고    scopus 로고
    • Detection of heat stable mycobacterial antigen in cerebrospinal fluid by Dot-Immunobinding assay
    • 1:STN:280:DC%2BD3szjtlClsw%3D%3D 12865516
    • A Mathai VV Radhakrishnan C Sarada SM George 2003 Detection of heat stable mycobacterial antigen in cerebrospinal fluid by Dot-Immunobinding assay Neurol India 51 52 54 1:STN:280:DC%2BD3szjtlClsw%3D%3D 12865516
    • (2003) Neurol India , vol.51 , pp. 52-54
    • Mathai, A.1    Radhakrishnan, V.V.2    Sarada, C.3    George, S.M.4
  • 29
    • 33748765834 scopus 로고    scopus 로고
    • Comparative evaluation of early diagnosis of tuberculous meningitis by different assays
    • 10.1128/JCM.00333-06 16954242
    • C Quan CZ Lu J Qiao, et al. 2006 Comparative evaluation of early diagnosis of tuberculous meningitis by different assays J Clin Microbiol 44 3160 3166 10.1128/JCM.00333-06 16954242
    • (2006) J Clin Microbiol , vol.44 , pp. 3160-3166
    • Quan, C.1    Lu, C.Z.2    Qiao, J.3
  • 30
    • 70349898589 scopus 로고    scopus 로고
    • Pharmacokinetics of moxifloxacin in cerebrospinal fluid and plasma in patients with tuberculous meningitis
    • 10.1086/605576 1:CAS:528:DC%2BD1MXhtlehs7rO 19712035 It has been almost 50 years since the introduction of a new first-line antimicrobial agent for the treatment of tuberculosis. Of currently available drugs, the new fluoroquinolones have the most promise. Moxifloxacin has the greatest in vitro activity against M. tuberculosis, and though published clinical data on its use in TBM are limited, this report is encouraging with regard to thinking about moxifloxacin as a reasonable second-line agent for TBM
    • JW Alffenaar R van Altena HJ Bokkerink, et al. 2009 Pharmacokinetics of moxifloxacin in cerebrospinal fluid and plasma in patients with tuberculous meningitis Clin Infect Dis 49 1080 1082 10.1086/605576 1:CAS:528: DC%2BD1MXhtlehs7rO 19712035 It has been almost 50 years since the introduction of a new first-line antimicrobial agent for the treatment of tuberculosis. Of currently available drugs, the new fluoroquinolones have the most promise. Moxifloxacin has the greatest in vitro activity against M. tuberculosis, and though published clinical data on its use in TBM are limited, this report is encouraging with regard to thinking about moxifloxacin as a reasonable second-line agent for TBM
    • (2009) Clin Infect Dis , vol.49 , pp. 1080-1082
    • Alffenaar, J.W.1    Van Altena, R.2    Bokkerink, H.J.3
  • 31
    • 0037441632 scopus 로고    scopus 로고
    • Treatment of tuberculosis
    • American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America. 10.1164/rccm.167.4.603
    • American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America 2003 Treatment of tuberculosis Am J Respir Crit Care Med 167 603 662 10.1164/rccm.167.4.603
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 603-662
  • 32
    • 0035864524 scopus 로고    scopus 로고
    • Novel treatment of meningitis caused by multidrug-resistant Mycobacterium tuberculosis with intrathecal levofloxacin and amikacin: Case report
    • 10.1086/318698 1:STN:280:DC%2BD3MvkslWmsA%3D%3D 11181130
    • SE Berning TA Cherry MD Iseman 2001 Novel treatment of meningitis caused by multidrug-resistant Mycobacterium tuberculosis with intrathecal levofloxacin and amikacin: case report Clin Infect Dis 32 643 646 10.1086/318698 1:STN:280:DC%2BD3MvkslWmsA%3D%3D 11181130
    • (2001) Clin Infect Dis , vol.32 , pp. 643-646
    • Berning, S.E.1    Cherry, T.A.2    Iseman, M.D.3
  • 33
    • 0037980249 scopus 로고    scopus 로고
    • A case of refractory tuberculous meningitis markedly improved by intrathecal administration of isoniazid (INH) [Japanese]
    • T Takahashi K Ogawa S Sawada, et al. 2003 A case of refractory tuberculous meningitis markedly improved by intrathecal administration of isoniazid (INH) [Japanese] Rinsho Shinkeigaku Clin Neurol 43 20 25
    • (2003) Rinsho Shinkeigaku Clin Neurol , vol.43 , pp. 20-25
    • Takahashi, T.1    Ogawa, K.2    Sawada, S.3
  • 34
    • 33646895670 scopus 로고    scopus 로고
    • Paradoxical response to chemotherapy in neurotuberculosis
    • 10.1159/000092357 16714861
    • R Kumar M Prakash S Jha 2006 Paradoxical response to chemotherapy in neurotuberculosis Pediatr Neurosurg 42 214 222 10.1159/000092357 16714861
    • (2006) Pediatr Neurosurg , vol.42 , pp. 214-222
    • Kumar, R.1    Prakash, M.2    Jha, S.3
  • 35
    • 0002837370 scopus 로고
    • Tuberculous meningitis treated with cortisone
    • 10.1016/S0140-6736(55)90003-9
    • M Ashby H Grant 1955 Tuberculous meningitis treated with cortisone Lancet 1 65 66 10.1016/S0140-6736(55)90003-9
    • (1955) Lancet , vol.1 , pp. 65-66
    • Ashby, M.1    Grant, H.2
  • 36
    • 0004994514 scopus 로고
    • The influence of corticosteroid hormones in the treatment of tuberculous meningitis in Negroes
    • 1:CAS:528:DyaF3MXmtVOlug%3D%3D
    • BF Voljavec RF Corpe 1960 The influence of corticosteroid hormones in the treatment of tuberculous meningitis in Negroes Am Rev Respir Dis 81 539 545 1:CAS:528:DyaF3MXmtVOlug%3D%3D
    • (1960) Am Rev Respir Dis , vol.81 , pp. 539-545
    • Voljavec, B.F.1    Corpe, R.F.2
  • 37
    • 0001278748 scopus 로고
    • The present status of the treatment of tuberculosis of the central nervous system
    • 10.1111/j.1749-6632.1963.tb16629.x 1:STN:280:DyaF387itFCmtg%3D%3D 13929802
    • MH Lepper HW Spies 1963 The present status of the treatment of tuberculosis of the central nervous system Ann NY Acad Sci 106 106 123 10.1111/j.1749-6632.1963.tb16629.x 1:STN:280:DyaF387itFCmtg%3D%3D 13929802
    • (1963) Ann NY Acad Sci , vol.106 , pp. 106-123
    • Lepper, M.H.1    Spies, H.W.2
  • 38
    • 0014442978 scopus 로고
    • Dexamethasone in tuberculous meningitis: Relationship of cerebrospinal fluid effects to therapeutic efficacy
    • 5304225
    • RD O'Toole GF Thornton MK Mukherjee RL Nath 1969 Dexamethasone in tuberculous meningitis: relationship of cerebrospinal fluid effects to therapeutic efficacy Ann Intern Med 70 39 48 5304225
    • (1969) Ann Intern Med , vol.70 , pp. 39-48
    • O'Toole, R.D.1    Thornton, G.F.2    Mukherjee, M.K.3    Nath, R.L.4
  • 39
    • 0016588395 scopus 로고
    • Mortality from tuberculous meningitis reduced by steroid therapy
    • 1:STN:280:DyaE28%2Fns12mtA%3D%3D 1105378
    • JA Escobar MA Belsey A Duenes P Medina 1975 Mortality from tuberculous meningitis reduced by steroid therapy Pediatrics 56 1050 1055 1:STN:280:DyaE28%2Fns12mtA%3D%3D 1105378
    • (1975) Pediatrics , vol.56 , pp. 1050-1055
    • Escobar, J.A.1    Belsey, M.A.2    Duenes, A.3    Medina, P.4
  • 40
    • 0020995360 scopus 로고
    • The use of dexamethasone in preventing ocular complications in tuberculous meningitis
    • 10.1016/0035-9203(83)90195-5 1:STN:280:DyaL2c%2FpvV2nsw%3D%3D 6659045
    • NI Girgis Z Farid LS Hanna, et al. 1983 The use of dexamethasone in preventing ocular complications in tuberculous meningitis Trans R Soc Trop Med Hyg 77 658 659 10.1016/0035-9203(83)90195-5 1:STN:280:DyaL2c%2FpvV2nsw%3D%3D 6659045
    • (1983) Trans R Soc Trop Med Hyg , vol.77 , pp. 658-659
    • Girgis, N.I.1    Farid, Z.2    Hanna, L.S.3
  • 41
    • 0025882368 scopus 로고
    • Dexamethasone adjunctive treatment for tuberculous meningitis
    • 10.1097/00006454-199103000-00002 1:STN:280:DyaK3M3lt1Wjsg%3D%3D 2041662
    • NI Girgis Z Farid ME Kilpatrick, et al. 1991 Dexamethasone adjunctive treatment for tuberculous meningitis Pediatr Infect Dis J 10 179 183 10.1097/00006454-199103000-00002 1:STN:280:DyaK3M3lt1Wjsg%3D%3D 2041662
    • (1991) Pediatr Infect Dis J , vol.10 , pp. 179-183
    • Girgis, N.I.1    Farid, Z.2    Kilpatrick, M.E.3
  • 42
    • 0028341162 scopus 로고
    • Randomized controlled trial of dexamethasone in tuberculous meningitis
    • 10.1016/0962-8479(94)90009-4
    • S Kumarvelu K Prasad A Khosla, et al. 1994 Randomized controlled trial of dexamethasone in tuberculous meningitis Tubercle Lung Dis 75 302 307 10.1016/0962-8479(94)90009-4
    • (1994) Tubercle Lung Dis , vol.75 , pp. 302-307
    • Kumarvelu, S.1    Prasad, K.2    Khosla, A.3
  • 43
    • 0029983055 scopus 로고    scopus 로고
    • Corticosteroid in tuberculous meningitis
    • 1:STN:280:DyaK2s%2FitFKmug%3D%3D 8868018
    • V Chotmongkol S Jitpimolmard Y Thavornpitak 1996 Corticosteroid in tuberculous meningitis J Med Assoc Thai 79 83 90 1:STN:280: DyaK2s%2FitFKmug%3D%3D 8868018
    • (1996) J Med Assoc Thai , vol.79 , pp. 83-90
    • Chotmongkol, V.1    Jitpimolmard, S.2    Thavornpitak, Y.3
  • 44
    • 0030964452 scopus 로고    scopus 로고
    • Effect of corticosteroids on intracranial pressure, computed tomographic findings, and clinical outcomes in young children with tuberculous meningitis
    • 10.1542/peds.99.2.226 1:STN:280:DyaK2s7ns12isA%3D%3D 9024451
    • JF Schoeman LE Van Zyl JA Laubscher PR Donald 1997 Effect of corticosteroids on intracranial pressure, computed tomographic findings, and clinical outcomes in young children with tuberculous meningitis Pediatrics 99 226 231 10.1542/peds.99.2.226 1:STN:280:DyaK2s7ns12isA%3D%3D 9024451
    • (1997) Pediatrics , vol.99 , pp. 226-231
    • Schoeman, J.F.1    Van Zyl, L.E.2    Laubscher, J.A.3    Donald, P.R.4
  • 45
    • 43049134642 scopus 로고    scopus 로고
    • Dexamethasone as adjunctive therapy in adult patients with probable TB meningitis stage II and stage III: An open randomised controlled trial
    • DV Lardizabal AA Roxas 1998 Dexamethasone as adjunctive therapy in adult patients with probable TB meningitis stage II and stage III: an open randomised controlled trial Philipp J Neurol 4 4 10
    • (1998) Philipp J Neurol , vol.4 , pp. 4-10
    • Lardizabal, D.V.1    Roxas, A.A.2
  • 46
    • 6044222465 scopus 로고    scopus 로고
    • Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults
    • 10.1056/NEJMoa040573 1:CAS:528:DC%2BD2cXovFSktrY%3D 15496623
    • GE Thwaites DB Nguyen HD Nguyen, et al. 2004 Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults New Engl J Med 351 1741 1751 10.1056/NEJMoa040573 1:CAS:528:DC%2BD2cXovFSktrY%3D 15496623
    • (2004) New Engl J Med , vol.351 , pp. 1741-1751
    • Thwaites, G.E.1    Nguyen, D.B.2    Nguyen, H.D.3
  • 47
    • 44949255452 scopus 로고    scopus 로고
    • Corticosteroids for managing tuberculous meningitis
    • 18254003 This systematic review examined seven randomized controlled trials (1140 patients) of adjunctive corticosteroids in TBM, and noted a significant improvement in mortality rate with steroid therapy. In the three trials that studied the composite endpoint of death or disabling residual neurologic deficit, a significant improvement was noted. The authors recommended dexamethasone or prednisolone for HIV-negative children (3-6 weeks of therapy) and adults (6 weeks of therapy) to reduce death and disabling residual neurologic deficit among survivors
    • K Prasad MB Singh 2008 Corticosteroids for managing tuberculous meningitis Cochrane Database Syst Rev 1 CD002244 18254003 This systematic review examined seven randomized controlled trials (1140 patients) of adjunctive corticosteroids in TBM, and noted a significant improvement in mortality rate with steroid therapy. In the three trials that studied the composite endpoint of death or disabling residual neurologic deficit, a significant improvement was noted. The authors recommended dexamethasone or prednisolone for HIV-negative children (3-6 weeks of therapy) and adults (6 weeks of therapy) to reduce death and disabling residual neurologic deficit among survivors
    • (2008) Cochrane Database Syst Rev , vol.1 , pp. 002244
    • Prasad, K.1    Singh, M.B.2
  • 48
    • 15944399098 scopus 로고    scopus 로고
    • Endoscopic third ventriculostomy in post-tubercular meningitic hydrocephalus: A preliminary report
    • 10.1055/s-2004-830183 1:STN:280:DC%2BD2M7hs1SqsA%3D%3D 15747217
    • D Singh V Sachdev AK Singh S Sinha 2005 Endoscopic third ventriculostomy in post-tubercular meningitic hydrocephalus: a preliminary report Minim Invasive Neurosurg 48 47 52 10.1055/s-2004-830183 1:STN:280:DC%2BD2M7hs1SqsA%3D%3D 15747217
    • (2005) Minim Invasive Neurosurg , vol.48 , pp. 47-52
    • Singh, D.1    Sachdev, V.2    Singh, A.K.3    Sinha, S.4
  • 49
    • 34347225591 scopus 로고    scopus 로고
    • Dural biopsy-an important prognostic indicator in tuberculous meningitis with hydrocephalus following shunt surgery
    • 17802970
    • SK Das D Ghosh A Singhi, et al. 2007 Dural biopsy-an important prognostic indicator in tuberculous meningitis with hydrocephalus following shunt surgery J Indian Med Assoc 105 12 15 17802970
    • (2007) J Indian Med Assoc , vol.105 , pp. 12-15
    • Das, S.K.1    Ghosh, D.2    Singhi, A.3
  • 50
    • 0032832222 scopus 로고    scopus 로고
    • Diagnosis and treatment of complicated tubercular meningitis
    • 10.1592/phco.19.15.1167.30575 1:STN:280:DyaK1MvktVKitQ%3D%3D 10512066
    • JJ Kelly EA Horowitz CJ Destache, et al. 1999 Diagnosis and treatment of complicated tubercular meningitis Pharmacotherapy 19 1167 1172 10.1592/phco.19.15.1167.30575 1:STN:280:DyaK1MvktVKitQ%3D%3D 10512066
    • (1999) Pharmacotherapy , vol.19 , pp. 1167-1172
    • Kelly, J.J.1    Horowitz, E.A.2    Destache, C.J.3


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