Life and death in aluminium-exposed cultures of rat lactotrophs studied by flow cytometry

Cell Biology and Toxicology

Volumn 26, Issue 4, 2010, Pages 341-353

  Calejo, Ana I ^a   Rodriguez, Eleazar ^a   Silva, Virgília S ^a   Jorgačevski, Jernej ^c   Stenovec, Matjaž ^b   Kreft, Marko ^b,c   Santos, Conceição ^a   Zorec, Robert ^b,c   Gonçalves, Paula P ^a  

^a UNIVERSITY OF AVEIRO   (Portugal)

^b Celica Biomedical Sciences Center   (Slovenia)

^c UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Aluminium toxicity; Cell viability testing; Lactotrophs in suspension cultures

Indexed keywords

ALUMINUM; CALCEIN; METHDILAZINE; PROLACTIN;

ALUMINUM OVERLOAD; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL AGGREGATION; CELL POPULATION; CELL SURVIVAL; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOFLUORESCENCE TEST; LIGHT SCATTERING; MALE; NONHUMAN; PRIORITY JOURNAL; PROLACTIN SECRETING CELL; RAT;

ALUMINUM COMPOUNDS; ANIMALS; CELL AGGREGATION; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CHLORIDES; FLOW CYTOMETRY; LACTOTROPHS; MALE; MICROSCOPY, CONFOCAL; RATS; RATS, WISTAR;

RATTUS;

EID: 77956266614     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10565-009-9147-5     Document Type: Article

References (40)

1. Abreo K, Jangula J, Jain SK, Sella M, Glass J. Aluminum uptake and toxicity in cultured mouse hepatocytes. J Am Soc Nephrol. 1991;1:1299-304.
2. Alessio L, Apostoli P, Ferioli A, Di Sipio I, Mussi I, Rigosa C. Behaviour of biological indicators of internal dose and some neuro-endocrine tests in aluminium workers. Med Lav. 1989;80:290-300.
3. Alfrey AC, LeGendre GR, Keahny WD. The dialysis encephalopathy syndrome-possible aluminum intoxication. N Engl J Med. 1976;294:184-8.
4. Allen VG, Fontenot JP, Rahnema SH. Influence of aluminumcitrate and citric acid on tissue mineral composition in wether sheep. J Anim Sci. 1991;69:792-800.
5. Aremu DA, Meshitsuka S. Accumulation of aluminum by primary cultured astrocytes from aluminum amino acid complex and its apoptotic effect. Brain Res. 2005;1031:284-96.
6. Authier FJ, Cherin P, Creange A, Bonnotte B, Ferrer X, Abdelmoumni A, et al. Central nervous system disease in patients with macrophagic myofasciitis. Brain. 2001;124:974-83.
7. Banasik A, Lankoff A, Piskulak A, Adamowska K, Lisowska H, Wojcik A. Aluminum-induced micronuclei and apoptosis in human peripheral-blood lymphocytes treated during different phases of the cell cycle. Environ Toxicol. 2005;20:402-6.
8. Ben-Jonathan N, Liby K, McFarland M, Zinger M. Prolactin as an autocrine/paracrine growth factor in human cancer. Trends Endocrinol Metab. 2002;13:245-50.
9. Ben-Tabou S, Keller E, Nussinovitch I. Mechanosensitivity of voltage-gated calcium currents in rat anterior pituitary cells. J Physiol. 1994;476:29-39.
10. Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA. Prolactin (PRL) and its receptors: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev. 1998;19:225-68.
11. Burrows HL, Douglas KR, Seasholtz AF, Camper SA. Genealogy of the anterior pituitary gland: tracing a family tree. Trends Endocrinol Metab. 1999;10:343-52.
12. Exley C. Aluminium and Alzheimer's disease: the science that describes the link. Amstersdam: Elsevier Science; 2001.
13. Exley C, Esiri MM. Severe cerebral congophilic angiopathy coincident with increased brain aluminium in a resident of Camelford, Cornwall, UK. J Neurol Neurosurg Psychiatr. 2006;77:877-9.
14. Fu H, Hu Q, Lin Z, Ren T, Song H, Cai C, et al. Aluminuminduced apoptosis in cultured cortical neurons and its effect on SAPK/JNK signal transduction pathway. Brain Res. 2003;980:11-23.
15. Galoyan AA, Shakhlamov VA, Aghajanov MI, Vahradyan HG. Hypothalamic proline-rich polypeptide protects brain neurons in aluminum neurotoxicosis. Neurochem Res. 2004;29:1349-57.
16. Hoorens A, Van de Casteele M, Klöppel G, Pipeleers D. Glucose promotes survival of rat pancreatic β cells by activating synthesis of proteins which suppress a constitutive apoptotic program. J Clin Invest. 1996;98:1568-74.
17. Johnson VJ, Kim SH, Sharma RP. Aluminum-maltolate induces apoptosis and necrosis in neuro-2a cells: potential role for p53 signaling. Toxicol Sci. 2005;83:329-39.
18. Lévesque A, Paquet A, Pagé M. Measurement of tumor necrosis factor activity by flow cytometry. Cytometry. 1995;20:181-4.
19. Lévesque L, Mizzen CA, McLachlan DR, Fraser PE. Ligand specific effects on aluminum incorporation and toxicity in neurons and astrocytes. Brain Res. 2000;877:191-202.
20. Lukiw WJ, Percy ME, Kruck TP. Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture. J Inorg Biochem. 2005;99:1895-8.
21. Mizoroki T, Meshitsuka S, Maeda S, Murayama M, Sahara N, Takashima A. Aluminum induces tau aggregation in vitro but not in vivo. J Alzheimers Dis. 2007;11:419-27.
22. Müller JP, Bruinink A. Neurotoxic effects of aluminium on embryonic chick brain cultures. Acta Neuropathol. 1994;88:359-66.
23. Nayak P. Aluminum: impacts and disease. Environ Res. 2002;89:101-15.
24. Niemoeller OM, Kiedaisch V, Dreischer P, Wieder T, Lang F. Stimulation of eryptosis by aluminium ions. Toxicol Appl Pharmacol. 2006;217:168-75.
25. Petrik MS, Wong MC, Tabata RC, Garry RF, Shaw CA. Aluminum adjuvant linked to Gulf War illness induces motor neuron death in mice. Neuromolecular Med. 2007;9:83-100.
26. Platt B, Drysdale AJ, Nday C, Roloff EL, Drever BD, Salifoglou A. Differential toxicity of novel aluminium compounds in hippocampal culture. Neurotoxicology. 2007;28:576-86.
27. Proesmans M, Van Bael A, Andries M, Denef C. Mitogenic effects of nerve growth factor on different cell types in reaggregate cell cultures of immature rat pituitary. Mol Cell Endocrinol. 1997;134:119-27.
28. Reusche E, Lindner B, Arnholdt H. Widespread aluminium deposition in extracerebral organ systems of patients with dialysis-associated encephalopathy. Virchows Arch. 1994;424:105-12.
29. Sánchez-Iglesias S, Soto-Otero R, Iglesias-González J, Barciela-Alonso MC, Bermejo-Barrera P, Méndez-Alvarez E. Analysis of brain regional distribution of aluminium in rats via oral and intraperitoneal administration. J Trace Elem Med Biol. 2007;21:31-4.
30. Sargazi M, Roberts NB, Shenkin A. In vitro studies of aluminium-induced toxicity on kidney proximal tubular cells. J Inorg Biochem. 2001;87:37-43.
31. Savory J, Ghribi O. Can studies of aluminum toxicity in vivo and in vitro provide relevant information on the pathogenesis and etiology of Alzheimer's disease? J Alzheimers Dis. 2007;11:429-30.
32. Savory J, Herman MM, Ghribi O. Mechanisms of aluminuminduced neurodegeneration in animals: implications for Alzheimer's disease. J Alzheimers Dis. 2006;10:135-44.
33. Suárez-Fernández MB, Soldado AB, Sanz-Medel A, Vega JA, Novelli A, Férnandez-Sánchez MT. Aluminum-induced degeneration of astrocytes occurs via apoptosis and results in neuronal death. Brain Res. 1999;835:125-36.
34. Toimela T, Tähti H. Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin. Arch Toxicol. 2004;78:565-74.
35. 26aluminum in rats measured by accelerator mass spectrometry. Clin Invest Med. 1994;17:420-5.
36. Walton JR. A bright field/fluorescent stain for aluminum: its specificity, validation, and staining characteristics. Biotech Histochem. 2004;79:169-76.
37. Yokel RA. Brain uptake, retention, and efflux of aluminum and manganese. Environ Health Perspect. 2002;110:699-704.
38. 26Al exposure. Toxicol Sci. 2001;64:77-82.
39. Zatta P, Favarato M, Nicolini M. Deposition of aluminium in brain tissues of rats exposed to inhalation of aluminium acetylacetonate. NeuroReport. 1993;4:1119-22.
40. Zhang QL, Boscolo P, Niu PY, Wang F, Shi YT, Zhang L, et al. How do rat cortical cells cultured with aluminum die: necrosis or apoptosis? Int J Immunopathol Pharmacol. 2008;21:107-15.