Development and validation of a nylon6 nanofibers mat-based SPE coupled with HPLC method for the determination of docetaxel in rabbit plasma and its application to the relative bioavailability study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 26, 2010, Pages 2403-2408

  Xu, Qian ^a,b   Zhang, Niping ^a,b   Yin, Xueyan ^a,b   Wang, Min ^a,b   Shen, Yanyan ^a,b   Xu, Shi ^a   Zhang, Ling ^a   Gu, Zhongze ^a,b  

^a SOUTHEAST UNIVERSITY   (China)

^b Suzhou Key Laboratory of Environment and Biosafety   (China)

Author keywords

Docetaxel; DTX SBE CD inclusion compound freeze dried powder; Electrospun nylon6 nanofibers mat; Relative bioavailability; Solid phase extraction

Indexed keywords

DOCETAXEL; ELECTROSPUNS; INCLUSION COMPOUNDS; RELATIVE BIOAVAILABILITY; SOLID-PHASE EXTRACTION;

BIOCHEMISTRY; DATA STORAGE EQUIPMENT; ETHERS; NANOFIBERS; PLASMAS; QUALITY CONTROL; STANDARDS;

EXTRACTION;

DOCETAXEL; NANOFIBER;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PLASMA; PRIORITY JOURNAL; RABBIT; SOLID PHASE EXTRACTION; VALIDATION STUDY;

ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CAPROLACTAM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FEMALE; LEAST-SQUARES ANALYSIS; MALE; NANOFIBERS; PACLITAXEL; POLYMERS; RABBITS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TAXOIDS;

ORYCTOLAGUS CUNICULUS;

EID: 77956264943     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.07.011     Document Type: Article

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