First quinquennial review of intensity-modulated radiotherapy at St Bartholomew's hospital, London

Clinical Oncology

Volumn 22, Issue 8, 2010, Pages 666-674

  Smith, D ^a   MacDougall, N ^a   Monk, J ^a   Sibtain, A ^a   Powell, M E ^a   Plowman, P N ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Commissioning; IMRT; Radiotherapy; Review

Indexed keywords

CETUXIMAB; CISPLATIN; IRON OXIDE;

ARTICLE; BRAIN METASTASIS; BREAST CANCER; CANCER RADIOTHERAPY; CLINICAL PRACTICE; ENDOMETRIUM CANCER; EXTERNAL BEAM RADIOTHERAPY; HEAD AND NECK CANCER; HODGKIN DISEASE; HUMAN; HYPOPHARYNX CANCER; INTENSITY MODULATED RADIATION THERAPY; LARYNX CANCER; LOADING DRUG DOSE; MEDICAL RESEARCH; MEDICAL TECHNOLOGY; NEUROBLASTOMA; OROPHARYNX CANCER; PARANASAL SINUS CANCER; PEDIATRIC ONCOLOGY NURSING; PELVIS CANCER; PRIORITY JOURNAL; QUALITY CONTROL; RADIATION DOSE; SALIVATION; TREATMENT PLANNING; UNITED KINGDOM; UTERINE CERVIX CANCER; XEROSTOMIA;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CEREBELLAR NEOPLASMS; FEMALE; HEAD AND NECK NEOPLASMS; HOSPITALS; HUMANS; LONDON; MALE; MEDULLOBLASTOMA; MIDDLE AGED; PELVIC NEOPLASMS; PRACTICE GUIDELINES AS TOPIC; QUALITY CONTROL; RADIOTHERAPY, INTENSITY-MODULATED; RHABDOMYOSARCOMA;

EID: 77956264208     PISSN: 09366555     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clon.2010.06.018     Document Type: Article

References (31)

1. Arnfield M.R., Siebers J.V., Kim J.O., Wu Q., Keall P.J., Mohan R. A method for determining multileaf collimator transmission and scatter for dynamic intensity modulated radiotherapy. Med Phys 2000, 27:2231-2241.
2. Van Esch A., Bohsung J., Sorvari P., et al. Acceptance tests and quality control (QC) procedures for the clinical implementation of intensity modulated radiotherapy (IMRT) using inverse planning and the sliding window technique: experience from five radiotherapy departments. Radiother Oncol 2002, 65:53-70.
3. Chauvet I., Petitfils A., Lehobey C., et al. The sliding slit test for dynamic IMRT: a useful tool for adjustment of MLC related parameters. Phys Med Biol 2005, 50:563-580.
4. LoSasso T., Chui C.S., Ling C.C. Physical and dosimetric aspects of an MLC system used in the dynamic mode for implementing intensity modulated radiotherapy. Med Phys 1998, 25:1919-1927.
5. IPEM Guidance for the clinical implementation of intensity-modulated radiation therapy 2008, Report 96, IPEM, London.
6. Monk J., MacDougall N. P65-Analysis of the sweeping gap test for routine QC with a Varian 120 leaf MLC. Clin Oncol 2007, 19(3):S40.
7. Venencia C.D., Besa P. Commissioning and quality assurance for intensity modulated radiotherapy with dynamic multileaf collimator: experience of the Pontificia Universidad Católica de Chile. J Appl Clin Med Phys 2004, 5:37-54.
8. Commowick O., Grégoire V., Malandain G. Atlas-based delineation of lymph node levels in head and neck computed tomography images. Radiother Oncol 2008, 87:281-289.
9. Chao K.S. Protection of salivary function by intensity-modulated radiation therapy in patients with head and neck cancer. Semin Radiat Oncol 2002, 12(1 S1):20-25.
10. Nutting C., A'Hern R., Rogers M.S., et al. First results of a phase III multicenter randomized controlled trial of intensity modulated (IMRT) versus conventional radiotherapy (RT) in head and neck cancer. J Clin Oncol 2009, 27:18S. (abstract LBA6006).
11. Maclean J.D., Michaelidou A., Sibtain A. P41 Intensity-modulated radiotherapy for head and neck cancer: a review of toxicity and outcome. Clin Oncol 2009, 21(3):273.
12. Bonin S.R., Lanciano R.M., Corn B.W., Hogan W.M., Hartz W.H., Hanks G.E. Bony landmarks are not an adequate substitute for lymphangiography in defining pelvic lymph node location for the treatment of cervical cancer with radiotherapy. Int J Radiat Oncol Biol Phys 1996, 34:167-172.
13. Weiss E., Eberlein K., Pradier O., Schmidberger H., Hess C.F. The impact of patient positioning on the adequate coverage of the uterus in the primary irradiation of cervical carcinoma: a prospective analysis using magnetic resonance imaging. Radiother Oncol 2002, 63:83-87.
14. Gerstner N., Wachter S., Knocke T.H., Fellner C., Wambersie A., Pötter R. The benefit of beam's eye view based 3D treatment planning for cervical cancer. Radiother Oncol 1999, 51:71-78.
15. Taylor A., Rockall A.G., Reznek R.H., Powell M.E. Mapping pelvic lymph nodes: guidelines for delineation in intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 2005, 63:1604-1612.
16. Vilarino-Varela M.J., Taylor A., Rockall A.G., Reznek R.H., Powell M.E. A verification study of proposed pelvic lymph node localisation guidelines using nanoparticle-enhanced magnetic resonance imaging. Radiother Oncol 2008, 89:192-196.
17. Taylor A., Rockall A.G., Powell M.E. An atlas of the pelvic lymph node regions to aid radiotherapy target volume definition. Clin Oncol 2007, 19:542-550.
18. Taylor A., Powell M.E. An assessment of interfractional uterine and cervical motion: implications for radiotherapy target volume definition in gynaecological cancer. Radiother Oncol 2008, 88:250-257.
19. Chan P., Dinniwell R., Haider M.A., et al. Inter- and intrafractional tumor and organ movement in patients with cervical cancer undergoing radiotherapy: a cinematic-MRI point-of-interest study. Int J Radiat Oncol Biol Phys 2008, 70:1507-1515.
20. Taylor A., Powell M.E.B. Conformal and intensity-modulated radiotherapy for cervical cancer. Clin Oncol 2008, 20:417-425.
21. DEPICT (Dose Escalation Pelvic IMRT in Cervical Tumours): a phase I/II dose escalation study of simultaneous integrated boost intensity-modulated radiotherapy for locally advanced cervical cancer Available at:, (accessed 15 June 2010). http://tinyurl.com/2wj8t7j.
22. Khoo V.S., Dearnaley D.P. Question of dose, fractionation and technique: ingredients for testing hypofractionation in prostate cancer - the CHHiP trial. Clin Oncol 2008, 20(1):12-14.
23. O'Donnell H., Cooke K., Walsh N., Plowman P.N. Early experience of tomotherapy-based intensity-modulated radiotherapy for breast cancer treatment. Clin Oncol 2009, 21:294-301.
24. Breen S.L., Kehagioglou P., Usher C., Plowman P.N. A comparison of conventional, conformal and intensity-modulated coplanar radiotherapy plans for posterior fossa treatment. Br J Radiol 2004, 77:768-774.
25. Plowman P.N., Cooke K., Walsh N. Indications for tomotherapy/intensity-modulated radiation therapy in paediatric radiotherapy: extracranial disease. Br J Radiol 2008, 81:872-880.
26. Andrews D.W., Scott C.B., Sperduto P.W., et al. Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial. Lancet 2004, 363:1665-1672.
27. Edwards A.A., Keggin E., Plowman P.N. The developing role of intensity modulated radiation therapy (IMRT) in the non-surgical treatment of brain metastases. Br J Radiol 2010, 83:133-136.
28. Mundt A.J., Mell L.K., Roeske J.C. Preliminary analysis of chronic gastrointestinal toxicity in gynecology patients treated with intensity-modulated whole pelvic radiation therapy. Int J Radiat Oncol Biol Phys 2003, 56:1354-1360.
29. Roeske J.C., Bonta D., Mell L.K., Lujan A.E., Mundt A.J. A dosimetric analysis of acute gastrointestinal toxicity in women receiving intensity modulated whole-pelvic radiation therapy. Radiother Oncol 2003, 69:201-207.
30. Donovan E., Bleakley N., Denholm E., et al. Randomised trial of standard 2D radiotherapy versus IMRT in patients prescribed breast radiotherapy. Radiother Oncol 2007, 82:254-264.
31. Coles C., Yarnold J. The IMPORT trials are launched. Clin Oncol 2006, 18:587-590.