Innate immune detection of bacterial virulence factors via the NLRC4 inflammasome

Journal of Clinical Immunology

Volumn 30, Issue 4, 2010, Pages 502-506

  Miao, Edward A ^a   Warren, Sarah E ^a,b  

^a INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Caspase 1; IL 1 ; Inflammation; NLRC4; Type III secretion

Indexed keywords

BACTERIAL PROTEIN; FLAGELLIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PROTEIN NLRC4; ROD PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR; CALCIUM BINDING PROTEIN; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; NLRC4 PROTEIN, HUMAN; PATTERN RECOGNITION RECEPTOR;

BACTERIAL CYTOSOL; BACTERIAL MEMBRANE; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIAL TRANSLOCATION; BACTERIAL VIRULENCE; CARD DOMAIN; CYTOKINE PRODUCTION; CYTOSOL; GASTROINTESTINAL TRACT; GRAM NEGATIVE BACTERIUM; HOST CELL; HOST PATHOGEN INTERACTION; INFLAMMATION; INNATE IMMUNITY; LEGIONELLA PNEUMOPHILA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT; REVIEW; SALMONELLA; SALMONELLA TYPHIMURIUM; TYPE III SECRETION SYSTEM; TYPE IV SECRETION SYSTEM; BACTERIA; HUMAN; IMMUNOLOGY; PATHOGENICITY;

BACTERIA; CALCIUM-BINDING PROTEINS; CARD SIGNALING ADAPTOR PROTEINS; HUMANS; IMMUNITY, INNATE; RECEPTORS, PATTERN RECOGNITION; VIRULENCE FACTORS;

EID: 77956263441     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-010-9386-5     Document Type: Review

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