Determination of esmolol and metabolite enantiomers within human plasma using chiral column chromatography

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 26, 2010, Pages 2449-2452

  Fang, Lei ^a   Bykowski Jurkiewicz, Crystal ^a   Sarver, Jeffrey G ^a   Erhardt, Paul W ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Chiral column chromatography; Enantiomers; Esmolol; Esmolol metabolite; HPLC; LC MS MS

Indexed keywords

CHIRAL COLUMN CHROMATOGRAPHY; ESMOLOL; ESMOLOL METABOLITE; HPLC; LC-MS/MS;

BIOMOLECULES; CHIRALITY; ENANTIOMERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; METABOLISM; METABOLITES; PLASMA (HUMAN); STEREOCHEMISTRY;

COLUMN CHROMATOGRAPHY;

DRUG METABOLITE; ESMOLOL;

ARTICLE; CHIRAL CHROMATOGRAPHY; DRUG DETERMINATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; PLASMA; PRIORITY JOURNAL; RACEMIC MIXTURE; TANDEM MASS SPECTROMETRY;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LINEAR MODELS; PROPANOLAMINES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM;

EID: 77956262517     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.07.006     Document Type: Article

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