-
1
-
-
0014007816
-
Early experiences with azathioprine in ulcerative colitis: a note of caution
-
Bowen, G.E., Irons, G.V., Rhodes, J.B. and Kirsner, J.B. ( 1966) Early experiences with azathioprine in ulcerative colitis: a note of caution. JAMA 195: 460-464.
-
(1966)
JAMA
, vol.195
, pp. 460-464
-
-
Bowen, G.E.1
Irons, G.V.2
Rhodes, J.B.3
Kirsner, J.B.4
-
2
-
-
0000284526
-
Clinical evaluation of a new antimetabolite, 6-mercaptopurine, in the treatment of leukaemia and allied diseases
-
Burchenal, J.H., Murphy, M.L., Ellison, R.R., Sykes, M.P., Tan, T.C., Leone, L.A. et al. (1953) Clinical evaluation of a new antimetabolite, 6-mercaptopurine, in the treatment of leukaemia and allied diseases. Blood 8: 965-999.
-
(1953)
Blood
, vol.8
, pp. 965-999
-
-
Burchenal, J.H.1
Murphy, M.L.2
Ellison, R.R.3
Sykes, M.P.4
Tan, T.C.5
Leone, L.A.6
-
3
-
-
0034093057
-
Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy
-
Colombel, J.F., Ferrari, N., Debuysere, H., Marteau, P., Gendre, J.P., Bonaz, B. et al. (2000) Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy. Gastroenterology 118: 1025-1030.
-
(2000)
Gastroenterology
, vol.118
, pp. 1025-1030
-
-
Colombel, J.F.1
Ferrari, N.2
Debuysere, H.3
Marteau, P.4
Gendre, J.P.5
Bonaz, B.6
-
4
-
-
2342420871
-
Thiopurine methyltransferase activity influences clinical response to azathioprine in inflammatory bowel disease
-
Cuffari, C., Dassopoulos, T., Turnbough, L., Thompson, R.E. and Bayless, T.M. ( 2004) Thiopurine methyltransferase activity influences clinical response to azathioprine in inflammatory bowel disease. Clin Gastroenterol Hepatol 2: 410-417.
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 410-417
-
-
Cuffari, C.1
Dassopoulos, T.2
Turnbough, L.3
Thompson, R.E.4
Bayless, T.M.5
-
5
-
-
0034067784
-
Pharmacogenetics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
-
Dubinsky, M.C., Lamothe, S., Yang, H.Y., Targan, S.R., Sinnett, D., Theoret, Y. et al. (2000) Pharmacogenetics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 118: 705-713.
-
(2000)
Gastroenterology
, vol.118
, pp. 705-713
-
-
Dubinsky, M.C.1
Lamothe, S.2
Yang, H.Y.3
Targan, S.R.4
Sinnett, D.5
Theoret, Y.6
-
6
-
-
27744574836
-
A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn's disease treated with azathioprine or 6-mercaptopurine
-
Dubinsky, M.C., Reyes, E., Ofman, J., Chiou, C.F., Wade, S. and Sandborn, W.J. ( 2005) A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn's disease treated with azathioprine or 6-mercaptopurine. Am J Gastroenterol 100: 2239-2247.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 2239-2247
-
-
Dubinsky, M.C.1
Reyes, E.2
Ofman, J.3
Chiou, C.F.4
Wade, S.5
Sandborn, W.J.6
-
7
-
-
0036202803
-
6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
-
Dubinsky, M.C., Yang, H., Hassard, P.V., Seidman, E.G., Kam, L.Y., Abreu, M.T. et al. (2002) 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology 122: 904-915.
-
(2002)
Gastroenterology
, vol.122
, pp. 904-915
-
-
Dubinsky, M.C.1
Yang, H.2
Hassard, P.V.3
Seidman, E.G.4
Kam, L.Y.5
Abreu, M.T.6
-
8
-
-
84993827320
-
-
Handbook of Experimental Pharmacology Springer-Verlag New York
-
Elion, G.B. and Hitchings, G.H. ( 1975) Azathioprine, In: Evenson, M.A. (ed.), Handbook of Experimental Pharmacology, Springer-Verlag: New York.
-
(1975)
Azathioprine
-
-
Elion, G.B.1
Hitchings, G.H.2
Evenson, M.A.3
-
9
-
-
0010229670
-
Studies on analogs of purines and pyrimidines
-
Hitchings, G.H., Elion, G.B., Falco, E.A., Russell, P.B. and Vanderwerff, H. ( 1950) Studies on analogs of purines and pyrimidines. Ann N Y Acad Sci 52: 1318-1335.
-
(1950)
Ann N Y Acad Sci
, vol.52
, pp. 1318-1335
-
-
Hitchings, G.H.1
Elion, G.B.2
Falco, E.A.3
Russell, P.B.4
Vanderwerff, H.5
-
10
-
-
0026758498
-
The clinical pharmacology of 6-mercaptopurine
-
Lennard, L. ( 1992) The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 43: 329-339.
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
11
-
-
0020512528
-
Childhood leukemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia
-
Lennard, L., Rees, C.A., Lilleyman, J.S. and Maddocks, J.L. ( 1983) Childhood leukemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia. Br J Clin Pharmacol 16: 359-363.
-
(1983)
Br J Clin Pharmacol
, vol.16
, pp. 359-363
-
-
Lennard, L.1
Rees, C.A.2
Lilleyman, J.S.3
Maddocks, J.L.4
-
12
-
-
0023119219
-
Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations
-
Lennard, L., van Loon, J.A., Lilleyman, J.S. and Weinshilboum, R.M. ( 1987) Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. Clin Pharmacol Ther 41: 18-25.
-
(1987)
Clin Pharmacol Ther
, vol.41
, pp. 18-25
-
-
Lennard, L.1
van Loon, J.A.2
Lilleyman, J.S.3
Weinshilboum, R.M.4
-
13
-
-
71749114818
-
Timing of myelosuppression during thiopurine therapy for inflammatory bowel disease: implications for monitoring recommendations
-
Lewis, J.D., Abramson, O., Pascua, M., Liu, L., Asakura, L.M., Velayos, F.S. et al. (2009) Timing of myelosuppression during thiopurine therapy for inflammatory bowel disease: implications for monitoring recommendations. Clin Gastroenterol Hepatol 7: 1195-1201.
-
(2009)
Clin Gastroenterol Hepatol
, vol.7
, pp. 1195-1201
-
-
Lewis, J.D.1
Abramson, O.2
Pascua, M.3
Liu, L.4
Asakura, L.M.5
Velayos, F.S.6
-
14
-
-
33646011261
-
Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis
-
Osterman, M.T., Kundu, R., Lichtenstein, G.R. and Lewis, J.D. ( 2006) Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology 130: 1047-1053.
-
(2006)
Gastroenterology
, vol.130
, pp. 1047-1053
-
-
Osterman, M.T.1
Kundu, R.2
Lichtenstein, G.R.3
Lewis, J.D.4
-
15
-
-
0018888679
-
Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study
-
Present, D.H., Korelitz, B.I., Wisch, N., Glass, J.L., Sachar, D.B. and Pasternack, B.S. ( 1980) Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study. N Engl J Med 302: 981-987.
-
(1980)
N Engl J Med
, vol.302
, pp. 981-987
-
-
Present, D.H.1
Korelitz, B.I.2
Wisch, N.3
Glass, J.L.4
Sachar, D.B.5
Pasternack, B.S.6
-
16
-
-
35449001530
-
Hepatotoxicity of 6-mercaptopurine (6-MP) and Azathioprine (AZA) in adult IBD patients
-
Shaye, O.A., Yadegari, M., Abreu, M.T., Poordad, F., Simon, K., Simon, K. et al. (2007) Hepatotoxicity of 6-mercaptopurine (6-MP) and Azathioprine (AZA) in adult IBD patients. Am J Gastroenterol 102: 2488-2494.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 2488-2494
-
-
Shaye, O.A.1
Yadegari, M.2
Abreu, M.T.3
Poordad, F.4
Simon, K.5
Simon, K.6
-
17
-
-
33846820178
-
Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine
-
Sparrow, M.P., Hande, S.A., Friedman, S., Cao, D. and Hanauer, S.B. ( 2007) Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine. Clin Gastroenterol Hepatol 5: 209-214.
-
(2007)
Clin Gastroenterol Hepatol
, vol.5
, pp. 209-214
-
-
Sparrow, M.P.1
Hande, S.A.2
Friedman, S.3
Cao, D.4
Hanauer, S.B.5
-
18
-
-
24344480999
-
Allopurinol safely and effectively optimizes thioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine
-
Sparrow, M.P., Hande, S.A., Friedman, S., Lim, W.C., Reddy, S.I., Cao, D. et al. (2005) Allopurinol safely and effectively optimizes thioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine. Aliment Pharmacol Ther 22: 441-446.
-
(2005)
Aliment Pharmacol Ther
, vol.22
, pp. 441-446
-
-
Sparrow, M.P.1
Hande, S.A.2
Friedman, S.3
Lim, W.C.4
Reddy, S.I.5
Cao, D.6
-
19
-
-
0242464926
-
CD28-dependent Rac 1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes
-
Tiede, I., Fritz, G., Strand, S., Poppe, D., Dvorsky, R., Strand, D. et al. (2003) CD28-dependent Rac 1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. J Clin Invest 111: 1133-1145.
-
(2003)
J Clin Invest
, vol.111
, pp. 1133-1145
-
-
Tiede, I.1
Fritz, G.2
Strand, S.3
Poppe, D.4
Dvorsky, R.5
Strand, D.6
-
20
-
-
65449156896
-
Leukopenia due to parvovirus B 19 in a Crohn's disease patient using azathioprine
-
van Asseldonk, D.P., Kanis, B.M., de Boer, N.K. and van Bodegraven, A.A. (2009) Leukopenia due to parvovirus B 19 in a Crohn's disease patient using azathioprine. Digestion 79: 211-214.
-
(2009)
Digestion
, vol.79
, pp. 211-214
-
-
van Asseldonk, D.P.1
Kanis, B.M.2
de Boer, N.K.3
van Bodegraven, A.A.4
-
21
-
-
0018822866
-
Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methytransferase activity
-
Weinshilboum, R.M. and Sladek, S.L. ( 1980) Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methytransferase activity. Am J Hum Genet 32: 651-662.
-
(1980)
Am J Hum Genet
, vol.32
, pp. 651-662
-
-
Weinshilboum, R.M.1
Sladek, S.L.2
-
22
-
-
0015246251
-
Controlled trial of azathioprine in Crohn's disease
-
Willoughby, J.T., Beckett, J., Kumar, P.J. and Dawson, A.M. ( 1971) Controlled trial of azathioprine in Crohn's disease. Lancet 298: 944-947.
-
(1971)
Lancet
, vol.298
, pp. 944-947
-
-
Willoughby, J.T.1
Beckett, J.2
Kumar, P.J.3
Dawson, A.M.4
-
23
-
-
4644241129
-
Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease
-
Winter, J., Walker, A., Shapiro, D., Gaffney, D., Spooner, R.J. and Mills, P.R. ( 2004) Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease. Aliment Pharmacol Ther 20: 593-599.
-
(2004)
Aliment Pharmacol Ther
, vol.20
, pp. 593-599
-
-
Winter, J.1
Walker, A.2
Shapiro, D.3
Gaffney, D.4
Spooner, R.J.5
Mills, P.R.6
-
24
-
-
34247159530
-
Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease
-
Winter, J.W., Gaffney, D., Shapiro, D., Spooner, R.J., Marinaki, A.M., Sanderson, A.M. et al. (2007) Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease. Aliment Pharmacol Ther 25: 1069-1077.
-
(2007)
Aliment Pharmacol Ther
, vol.25
, pp. 1069-1077
-
-
Winter, J.W.1
Gaffney, D.2
Shapiro, D.3
Spooner, R.J.4
Marinaki, A.M.5
Sanderson, A.M.6
|