Ganoderma lucidum polysaccharides attenuate endotoxin-induced intercellular cell adhesion molecule-1 expression in cultured smooth muscle cells and in the neointima in mice

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 17, 2010, Pages 9563-9571

  Lin, Ching Yuang ^a   Chen, Yung Hsiang ^a   Lin, Chia Ying ^b   Hsu, Hsien Yeh ^c   Wang, Shu Huei ^b   Liang, Chan Jung ^b   Kuan, I I ^b   Wu, Pei Jhen ^b   Pai, Pei Ying ^a   Wu, Chau Chung ^d   Chen, Yuh Lien ^b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

adhesion molecule; Ganoderma lucidum polysaccharides; MAPKs; smooth muscle cells; vascular diseases

Indexed keywords

ADHESION MOLECULES; GANODERMA LUCIDUM; MAPKS; SMOOTH MUSCLE CELLS; VASCULAR DISEASE;

ADHESION; BIOMOLECULES; BODY FLUIDS; CELL ADHESION; CELLS; MOLECULES; NUCLEIC ACIDS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; POLYSACCHARIDES;

MUSCLE;

ENDOTOXIN; INTERCELLULAR ADHESION MOLECULE 1; POLYSACCHARIDE;

ANIMAL; ARTICLE; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GANODERMA LUCIDUM; GENETICS; INTIMA; METABOLISM; MOUSE; SMOOTH MUSCLE;

ANIMALS; CELLS, CULTURED; ENDOTOXINS; INTERCELLULAR ADHESION MOLECULE-1; MICE; MUSCLE, SMOOTH; POLYSACCHARIDES; REISHI; TUNICA INTIMA;

GANODERMA LUCIDUM; MUS;

EID: 77956233299     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf100508j     Document Type: Article

References (36)

1. Ross, R. Atherosclerosis - An inflammatory disease N. Engl. J. Med. 1999, 340, 115-126
2. Braun, M.; Pietsch, P.; Schrör, K.; Baumann, G.; Felix, S. B. Cellular adhesion molecules on vascular smooth muscle cells Cardiovasc. Res. 1999, 41, 395-401
3. Collins, T.; Read, M. A.; Neish, A. S.; Whitley, M. Z.; Thanos, D.; Maniatis, T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers FASEB J. 1995, 9, 899-909
4. Muslin, A. J. MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets Clin. Sci. 2008, 115, 203-218
5. Haverslag, R.; Pasterkamp, G.; Hoefer, I. E. Targeting adhesion molecules in cardiovascular disorders. Cardiovasc Hematol. Disord.: Drug Targets 2008, 8, 252-260
6. Shiao, M. S. Natural products of the medicinal fungus Ganoderma lucidum: Occurrence, biological activities, and pharmacological functions Chem. Rec. 2003, 3, 172-180
7. Wang, Y. Y.; Khoo, K. H.; Chen, S. T.; Lin, C. C.; Wong, C. H.; Lin, C. H. Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: Functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities Bioorg. Med. Chem. 2002, 10, 1057-1062
8. Gao, Y.; Gao, H.; Chan, E.; Tang, W.; Xu, A.; Yang, H.; Huang, M.; Lan, J.; Duan, W.; Xu, C.; Zhou, S. Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum, in mice Immunol. Invest. 2005, 34, 171-198
9. Miyazaki, T.; Nishijima, M. Studies on fungal polysaccharides. XXVII. Structural examination of a water-soluble, antitumor polysaccharide of Ganoderma lucidum Chem. Pharm. Bull. 1981, 29, 3611-3616
10. Sun, J.; He, H.; Xie, B. J. Novel antioxidant peptides from fermented mushroom Ganoderma lucidum J. Agric. Food Chem. 2004, 52, 6646-6652
11. Wang, S. Y.; Hsu, M. L.; Hsu, H. C.; Tzeng, C. H.; Lee, S. S.; Shiao, M. S.; Ho, C. K. The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes Int. J. Cancer 1997, 70, 699-705
12. Hsu, H. Y.; Hua, K. F.; Lin, C. C.; Lin, C. H.; Hsu, J.; Wong, C. H. Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways J. Immunol. 2004, 173, 5989-5999
13. Lieu, C. W.; Lee, S. S.; Wang, S. Y. The effect of Ganoderma lucidum on induction of differentiation in leukemic U937 cells Anticancer Res. 1992, 12, 1211-1215
14. Cao, L. Z.; Lin, Z. B. Regulation on maturation and function of dendritic cells by Ganoderma lucidum polysaccharides Immunol. Lett. 2002, 83, 163-169
15. Woo, C. W. H.; Man, R. Y. K.; Siow, Y. L.; Choy, P. C.; Wan, E. W. Y.; Lau, C. S.; Karmin, O. Ganoderma lucidum inhibits inducible nitric oxide synthase expression in macrophages Mol. Cell. Biochem. 2005, 275, 165-171
16. Jiang, J.; Slivova, V.; Valachovicova, T.; Harvey, K.; Sliva, D. Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3 Int. J. Oncol. 2004, 24, 1093-1099
17. Lin, Y. L.; Liang, Y. C.; Lee, S. S.; Chiang, B. L. Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-κB and p38 mitogen-activated protein kinase pathways J. Leukocyte Biol. 2005, 78, 533-543
18. Sata, M.; Maejima, Y.; Adachi, F.; Fukino, K.; Saiura, A.; Sugiura, S.; Aoyagi, T.; Imai, Y.; Kurihara, H.; Kimura, K.; Omata, M.; Makuuchi, M.; Hirata, Y.; Nagai, R. A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia J. Mol. Cell Cardiol. 2000, 32, 2097-2104
19. Brennan, C. M.; Steitz, J. A. HuR and mRNA stability Cell. Mol. Life Sci. 2001, 58, 266-277
20. Jersmann, H. P. A.; Hii, C. S. T.; Ferrante, J. V.; Ferrante, A. Bacterial lipopolysaccharide and tumor necrosis factor α synergistically increase expression of human endothelial adhesion molecules through activation of NF-κB and p38 mitogen-activated protein kinase signaling pathways Infect. Immun. 2001, 69, 1273-1279
21. Lai, K. N.; Chan, L. Y. Y.; Tang, S. C. W.; Leung, J. C. K. Ganoderma extract prevents albumin-induced oxidative damage and chemokines synthesis in cultured human proximal tubular epithelial cells Nephrol., Dial., Transplant. 2006, 21, 1188-1197
22. Ho, Y. W.; Yeung, J. S. L.; Chiu, P. K. Y.; Tang, W. M.; Lin, Z. B.; Man, R. Y. K.; Lau, C. S. Ganoderma lucidum polysaccharide peptide reduced the production of proinflammatory cytokines in activated rheumatoid synovial fibroblast Mol. Cell. Biochem. 2007, 301, 173-179
23. Hua, K. F.; Hsu., H. Y.; Chao, L. K.; Chen, S. T.; Yang, W. B.; Hsu, J.; Wong, C. H. Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression J. Cell. Physiol. 2007, 212, 537-550
24. Wu, S. Q.; Aird, W. C. Thrombin, TNF-α, and LPS exert overlapping but nonidentical effects on gene expression in endothelial cells and vascular smooth muscle cells Am. J. Physiol. Heart Circ. Physiol. 2005, 289, 873-885
25. Champelovier, P.; Pautre, V.; ElAtifi, M.; Dupré, I.; Rostaing, B.; Michoud, A.; Berger, F.; Seigneurin, D. Resistance to phorbol ester-induced differentiation in human myeloid leukemia cells: A hypothetic role for the mRNA stabilization process Leuk. Res. 2006, 30, 1407-1416
26. McMullen, M. R.; Cocuzzi, E.; Hatzoglou, M.; Nagy, L. E. Chronic ethanol exposure increases the binding of HuR to the TNFα 3′-untranslated region in macrophages J. Biol. Chem. 2003, 278, 38333-38341
27. Heo, S. K.; Yun, H. J.; Noh, E. K.; Park, W. H.; Park, S. D. LPS induces inflammatory responses in human aortic vascular smooth muscle cells via Toll-like receptor 4 expression and nitric oxide production Immunol. Lett. 2008, 120, 57-64
28. Chen, Y. L.; Hu, C. S.; Lin, F. Y.; Chen, Y. H.; Sheu, L. M.; Ku, H. H.; Shiao, M. S.; Chen, J. W.; Lin, S. J. Salvianolic acid B attenuates cyclooxygenase-2 expression in vitro in LPS-treated human aortic smooth muscle cells and in vivo in the apolipoprotein-E-deficient mouse aorta J. Cell. Biochem. 2006, 98, 618-631
29. Thyagarajan, A.; Jiang, J.; Hopf, A.; Adamec, J.; Sliva, D. Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion Int. J. Mol. Med. 2006, 18, 657-664
30. Stanley, G.; Harvey, K.; Slivova, V.; Jiang, J.; Sliva, D. Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-β1 from prostate cancer cells Biochem. Biophys. Res. Commun. 2005, 330, 46-52
31. Hsu, H. Y.; Hua, K. F.; Wu, W. C.; Hsu, J.; Weng, S. T.; Lin, T. l.; Lin, C. Y.; Liu, C. Y.; Hseu, R. S.; Huang, C. T. Reishi immuno-modulation protein induces interleukin-2 expression via protein kinase-dependent signaling pathways within human T cells J. Cell. Physiol. 2008, 215, 15-26
32. Jiang, J.; Slivova, V.; Sliva, D. Ganoderma lucidum inhibits proliferation of human breast cancer cells by down-regulation of estrogen receptor and NF-κB signaling Int. J. Oncol. 2006, 29, 695-703
33. Ghosh, S.; Baltimore, D. Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B Nature 1990, 344, 678-682
34. Zhang, H. N.; Lin, Z. B. Hypoglycemic effect of Ganoderma lucidum polysaccharides Acta Pharmacol. Sin. 2004, 25, 191-195
35. Zhao, H. B.; Lin, S. Q.; Liu, J. H.; Lin, Z. B. Polysaccharide extract isolated from Ganoderma lucidum protects rat cerebral cortical neurons from hypoxia/reoxygenation injury J. Pharmacol. Sci. 2004, 95, 294-298
36. Danenberg, H. D.; Welt, F. G. P.; Walker, M., III; Seifert, P.; Toegel, G. S.; Edelman, E. R. Systemic inflammation induced by lipopolysaccharide increases neointimal formation after balloon and stent injury in rabbits Circulation 2002, 105, 2917-2922