메뉴 건너뛰기




Volumn 207, Issue 9, 2010, Pages 1825-1833

Estrogen promotes cutaneous wound healing via estrogen receptor β independent of its antiinflammatory activities

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; PROTEINASE;

EID: 77956232490     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20100500     Document Type: Article
Times cited : (126)

References (29)
  • 1
    • 1842867053 scopus 로고    scopus 로고
    • Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The Women's Health Initiative randomized controlled trial
    • Women's Health Initiative Steering Committee doi:10.1001/jama.291.14.1701
    • Anderson, G.L., M. Limacher, A.R. Assaf, T. Bassford, S.A. Beresford, H. Black, D. Bonds, R. Brunner, R. Brzyski, B. Caan, et al; Women's Health Initiative Steering Committee. 2004. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 291:1701-1712. doi:10.1001/jama.291.14.1701
    • (2004) JAMA , vol.291 , pp. 1701-1712
    • Anderson, G.L.1    Limacher, M.2    Assaf, A.R.3    Bassford, T.4    Beresford, S.A.5    Black, H.6    Bonds, D.7    Brunner, R.8    Brzyski, R.9    Caan, B.10
  • 2
    • 40649084350 scopus 로고    scopus 로고
    • Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant
    • doi:10.1073/pnas.0712029105
    • Antal, M.C., A. Krust, P. Chambon, and M. Mark. 2008. Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant. Proc. Natl. Acad. Sci. USA. 105:2433-2438. doi:10.1073/pnas.0712029105
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 2433-2438
    • Antal, M.C.1    Krust, A.2    Chambon, P.3    Mark, M.4
  • 3
    • 0030669690 scopus 로고    scopus 로고
    • Estrogen accelerates cutaneous wound healing associated with an increase in TGF-beta1 levels
    • doi:10.1038/nm1197-1209
    • Ashcroft, G.S., J. Dodsworth, E. van Boxtel, R.W. Tarnuzzer, M.A. Horan, G.S. Schultz, and M.W. Ferguson. 1997. Estrogen accelerates cutaneous wound healing associated with an increase in TGF-beta1 levels. Nat. Med. 3:1209-1215. doi:10.1038/nm1197-1209
    • (1997) Nat. Med. , vol.3 , pp. 1209-1215
    • Ashcroft, G.S.1    Dodsworth, J.2    Van Boxtel, E.3    Tarnuzzer, R.W.4    Horan, M.A.5    Schultz, G.S.6    Ferguson, M.W.7
  • 4
    • 37249030347 scopus 로고    scopus 로고
    • Polymorphisms spanning the 0N exon and promoter of the estrogen receptor-beta (ERbeta) gene ESR2 are associated with venous ulceration
    • doi:10.1111/j.1399-0004.2007.00927.x
    • Ashworth, J.J., J.V. Smyth, N. Pendleton, M. Horan, A. Payton, J. Worthington, W.E. Ollier, and G.S. Ashcroft. 2008. Polymorphisms spanning the 0N exon and promoter of the estrogen receptor-beta (ERbeta) gene ESR2 are associated with venous ulceration. Clin. Genet. 73:55-61. doi:10.1111/j.1399- 0004.2007.00927.x
    • (2008) Clin. Genet. , vol.73 , pp. 55-61
    • Ashworth, J.J.1    Smyth, J.V.2    Pendleton, N.3    Horan, M.4    Payton, A.5    Worthington, J.6    Ollier, W.E.7    Ashcroft, G.S.8
  • 5
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • doi:10.1023/A:1008942828960
    • Clausen, B.E., C. Burkhardt, W. Reith, R. Renkawitz, and I. Förster. 1999. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8:265-277. doi:10.1023/A:1008942828960
    • (1999) Transgenic Res. , vol.8 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3    Renkawitz, R.4    Förster, I.5
  • 6
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice: What have we learned and where will they lead us?
    • doi:10.1210/er.20.3.358
    • Couse, J.F., and K.S. Korach. 1999. Estrogen receptor null mice: what have we learned and where will they lead us? Endocr. Rev. 20:358-417. doi:10.1210/er.20.3.358
    • (1999) Endocr. Rev. , vol.20 , pp. 358-417
    • Couse, J.F.1    Korach, K.S.2
  • 8
    • 0345014915 scopus 로고    scopus 로고
    • Excessive neutrophils characterize chronic pressure ulcers
    • doi:10.1046/j.1524-475X.2003.11617.x
    • Diegelmann, R.F. 2003. Excessive neutrophils characterize chronic pressure ulcers. Wound Repair Regen. 11:490-495. doi:10.1046/j.1524-475X.2003. 11617.x
    • (2003) Wound Repair Regen. , vol.11 , pp. 490-495
    • Diegelmann, R.F.1
  • 9
    • 0033767836 scopus 로고    scopus 로고
    • Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes
    • Dupont, S., A. Krust, A. Gansmuller, A. Dierich, P. Chambon, and M. Mark. 2000. Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. Development. 127:4277-4291.
    • (2000) Development , vol.127 , pp. 4277-4291
    • Dupont, S.1    Krust, A.2    Gansmuller, A.3    Dierich, A.4    Chambon, P.5    Mark, M.6
  • 10
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • doi:10.1056/NEJM198612253152606
    • Dvorak, H.F. 1986. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 315:1650-1659. doi:10.1056/NEJM198612253152606
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 11
    • 66649121430 scopus 로고    scopus 로고
    • Unique and synergistic roles for 17beta-estradiol and macrophage migration inhibitory factor during cutaneous wound closure are cell type specific
    • doi:10.1210/en.2008-1569
    • Emmerson, E., L. Campbell, G.S. Ashcroft, and M.J. Hardman. 2009. Unique and synergistic roles for 17beta-estradiol and macrophage migration inhibitory factor during cutaneous wound closure are cell type specific. Endocrinology. 150:2749-2757. doi:10.1210/en.2008-1569
    • (2009) Endocrinology , vol.150 , pp. 2749-2757
    • Emmerson, E.1    Campbell, L.2    Ashcroft, G.S.3    Hardman, M.J.4
  • 12
    • 34547931089 scopus 로고    scopus 로고
    • Androgens influence expression of matrix proteins and proteolytic factors during cutaneous wound healing
    • doi:10.1038/labinvest.3700627
    • Gilliver, S.C., J.P. Ruckshanthi, S.J. Atkinson, and G.S. Ashcroft. 2007. Androgens influence expression of matrix proteins and proteolytic factors during cutaneous wound healing. Lab. Invest. 87:871-881. doi:10.1038/labinvest. 3700627
    • (2007) Lab. Invest. , vol.87 , pp. 871-881
    • Gilliver, S.C.1    Ruckshanthi, J.P.2    Atkinson, S.J.3    Ashcroft, G.S.4
  • 14
    • 47149099393 scopus 로고    scopus 로고
    • Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly
    • doi:10.1186/gb-2008-9-5-r80
    • Hardman, M.J., and G.S. Ashcroft. 2008. Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly. Genome Biol. 9:R80. doi:10.1186/gb-2008-9-5-r80
    • (2008) Genome Biol. , vol.9
    • Hardman, M.J.1    Ashcroft, G.S.2
  • 15
    • 0035091032 scopus 로고    scopus 로고
    • RXR-alpha ablation in skin keratinocytes results in alopecia and epidermal alterations
    • Li, M., H. Chiba, X. Warot, N. Messaddeq, C. Gérard, P. Chambon, and D. Metzger. 2001. RXR-alpha ablation in skin keratinocytes results in alopecia and epidermal alterations. Development. 128:675-688.
    • (2001) Development , vol.128 , pp. 675-688
    • Li, M.1    Chiba, H.2    Warot, X.3    Messaddeq, N.4    Gérard, C.5    Chambon, P.6    Metzger, D.7
  • 16
    • 0037314762 scopus 로고    scopus 로고
    • Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice
    • doi:10.1210/me.2002-0206
    • Lindberg, M.K., S. Movérare, S. Skrtic, H. Gao, K. Dahlman-Wright, J.A. Gustafsson, and C. Ohlsson. 2003. Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice. Mol. Endocrinol. 17:203-208. doi:10.1210/me.2002-0206
    • (2003) Mol. Endocrinol. , vol.17 , pp. 203-208
    • Lindberg, M.K.1    Movérare, S.2    Skrtic, S.3    Gao, H.4    Dahlman-Wright, K.5    Gustafsson, J.A.6    Ohlsson, C.7
  • 17
    • 33144474647 scopus 로고    scopus 로고
    • Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland
    • doi:10.1073/pnas.0510974103
    • Mallepell, S., A. Krust, P. Chambon, and C. Brisken. 2006. Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland. Proc. Natl. Acad. Sci. USA. 103:2196-2201. doi:10.1073/pnas.0510974103
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2196-2201
    • Mallepell, S.1    Krust, A.2    Chambon, P.3    Brisken, C.4
  • 18
    • 0037160758 scopus 로고    scopus 로고
    • Hormone replacement therapy and prevention of pressure ulcers and venous leg ulcers
    • doi:10.1016/S0140-6736(02)07806-6
    • Margolis, D.J., J. Knauss, and W. Bilker. 2002. Hormone replacement therapy and prevention of pressure ulcers and venous leg ulcers. Lancet. 359:675-677. doi:10.1016/S0140-6736(02)07806-6
    • (2002) Lancet , vol.359 , pp. 675-677
    • Margolis, D.J.1    Knauss, J.2    Bilker, W.3
  • 19
    • 67449152697 scopus 로고    scopus 로고
    • Differential involvement of estrogen receptor alpha and estrogen receptor beta in the healing promoting effect of estrogen in human keratinocytes
    • doi:10.1677/JOE-08-0442
    • Merlo, S., G. Frasca, P.L. Canonico, and M.A. Sortino. 2009. Differential involvement of estrogen receptor alpha and estrogen receptor beta in the healing promoting effect of estrogen in human keratinocytes. J. Endocrinol. 200:189-197. doi:10.1677/JOE-08-0442
    • (2009) J. Endocrinol. , vol.200 , pp. 189-197
    • Merlo, S.1    Frasca, G.2    Canonico, P.L.3    Sortino, M.A.4
  • 20
    • 73549118560 scopus 로고    scopus 로고
    • Selective and specific macrophage ablation is detrimental to wound healing in mice
    • doi:10.2353/ajpath.2009.090248
    • Mirza, R., L.A. DiPietro, and T.J. Koh. 2009. Selective and specific macrophage ablation is detrimental to wound healing in mice. Am. J. Pathol. 175:2454-2462. doi:10.2353/ajpath.2009.090248
    • (2009) Am. J. Pathol. , vol.175 , pp. 2454-2462
    • Mirza, R.1    DiPietro, L.A.2    Koh, T.J.3
  • 21
    • 0036450375 scopus 로고    scopus 로고
    • Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the hair follicle cycling as well as the thickness of epidermis in male mice
    • doi:10.1046/j.1523-1747.2002.00637.x
    • Movérare, S., M.K. Lindberg, J. Faergemann, J.A. Gustafsson, and C. Ohlsson. 2002. Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the hair follicle cycling as well as the thickness of epidermis in male mice. J. Invest. Dermatol. 119:1053-1058. doi:10.1046/j.1523-1747.2002.00637.x
    • (2002) J. Invest. Dermatol. , vol.119 , pp. 1053-1058
    • Movérare, S.1    Lindberg, M.K.2    Faergemann, J.3    Gustafsson, J.A.4    Ohlsson, C.5
  • 22
    • 14344261415 scopus 로고    scopus 로고
    • Hair cycle control by estrogens: Catagen induction via estrogen receptor (ER)- Alpha is checked by ER beta signaling
    • doi:10.1210/en.2004-1219
    • Ohnemus, U., M. Uenalan, F. Conrad, B. Handjiski, L. Mecklenburg, M. Nakamura, J. Inzunza, J.A. Gustafsson, and R. Paus. 2005. Hair cycle control by estrogens: catagen induction via estrogen receptor (ER)- alpha is checked by ER beta signaling. Endocrinology. 146:1214-1225. doi:10.1210/en.2004-1219
    • (2005) Endocrinology , vol.146 , pp. 1214-1225
    • Ohnemus, U.1    Uenalan, M.2    Conrad, F.3    Handjiski, B.4    Mecklenburg, L.5    Nakamura, M.6    Inzunza, J.7    Gustafsson, J.A.8    Paus, R.9
  • 23
    • 1642535535 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest
    • doi:10.1158/0008-5472.CAN-03-2446
    • Paruthiyil, S., H. Parmar, V. Kerekatte, G.R. Cunha, G.L. Firestone, and D.C. Leitman. 2004. Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res. 64:423-428. doi:10.1158/0008-5472.CAN-03-2446
    • (2004) Cancer Res. , vol.64 , pp. 423-428
    • Paruthiyil, S.1    Parmar, H.2    Kerekatte, V.3    Cunha, G.R.4    Firestone, G.L.5    Leitman, D.C.6
  • 24
    • 0042872483 scopus 로고    scopus 로고
    • The distribution of estrogen receptor beta is distinct to that of estrogen receptor alpha and the androgen receptor in human skin and the pilosebaceous unit
    • doi:10.1046/j.1523-1747.2003.12181.x
    • Thornton, M.J., A.H. Taylor, K. Mulligan, F. Al-Azzawi, C.C. Lyon, J. O'Driscoll, and A.G. Messenger. 2003a. The distribution of estrogen receptor beta is distinct to that of estrogen receptor alpha and the androgen receptor in human skin and the pilosebaceous unit. J. Investig. Dermatol. Symp. Proc. 8:100-103. doi:10.1046/j.1523-1747.2003.12181.x
    • (2003) J. Investig. Dermatol. Symp. Proc. , vol.8 , pp. 100-103
    • Thornton, M.J.1    Taylor, A.H.2    Mulligan, K.3    Al-Azzawi, F.4    Lyon, C.C.5    O'Driscoll, J.6    Messenger, A.G.7
  • 25
    • 0041742207 scopus 로고    scopus 로고
    • Oestrogen receptor beta is the predominant oestrogen receptor in human scalp skin
    • doi:10.1034/j.1600-0625.2003.120209.x
    • Thornton, M.J., A.H. Taylor, K. Mulligan, F. Al-Azzawi, C.C. Lyon, J. O'Driscoll, and A.G. Messenger. 2003b. Oestrogen receptor beta is the predominant oestrogen receptor in human scalp skin. Exp. Dermatol. 12:181-190. doi:10.1034/j.1600-0625.2003.120209.x
    • (2003) Exp. Dermatol. , vol.12 , pp. 181-190
    • Thornton, M.J.1    Taylor, A.H.2    Mulligan, K.3    Al-Azzawi, F.4    Lyon, C.C.5    O'Driscoll, J.6    Messenger, A.G.7
  • 26
    • 35548975206 scopus 로고    scopus 로고
    • Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment
    • doi:10.1073/pnas.0703783104
    • Tiwari-Woodruff, S., L.B. Morales, R. Lee, and R.R. Voskuhl. 2007. Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment. Proc. Natl. Acad. Sci. USA. 104:14813-14818. doi:10.1073/pnas.0703783104
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 14813-14818
    • Tiwari-Woodruff, S.1    Morales, L.B.2    Lee, R.3    Voskuhl, R.R.4
  • 28
    • 9444254073 scopus 로고    scopus 로고
    • Estradiol induces proliferation of keratinocytes via a receptor mediated mechanism
    • Verdier-Sevrain, S., M. Yaar, J. Cantatore, A. Traish, and B.A. Gilchrest. 2004. Estradiol induces proliferation of keratinocytes via a receptor mediated mechanism. FASEB J. 18:1252-1254.
    • (2004) FASEB J. , vol.18 , pp. 1252-1254
    • Verdier-Sevrain, S.1    Yaar, M.2    Cantatore, J.3    Traish, A.4    Gilchrest, B.A.5
  • 29
    • 0027202705 scopus 로고
    • Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9
    • doi:10.1111/1523-1747.ep12359590
    • Wysocki, A.B., L. Staiano-Coico, and F. Grinnell. 1993. Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9. J. Invest. Dermatol. 101:64-68. doi:10.1111/1523-1747.ep12359590
    • (1993) J. Invest. Dermatol. , vol.101 , pp. 64-68
    • Wysocki, A.B.1    Staiano-Coico, L.2    Grinnell, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.