Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to rel DNA-binding proteins and a novel dimerization motif

Journal of Biological Chemistry

Volumn 285, Issue 34, 2010, Pages 25875-25879

  Siponen, Marina I ^a   Wisniewska, Magdalena ^a,b,c   Lehtiö, Lari ^b   Johansson, Ida ^a   Svensson, Linda ^a   Raszewski, Grzegorz ^a   Nilsson, Lennart ^a   Sigvardsson, Mikael ^c   Berglund, Helena ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ÅBO AKADEMI UNIVERSITY   (Finland)

^c LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DNA-BINDING PROTEIN; FUNCTIONAL DOMAINS; MODULAR APPROACH; PROTEIN FAMILY; SEQUENCE SIMILARITY; STRUCTURAL DETERMINATION; STRUCTURAL FEATURE; STRUCTURAL INFORMATION; ZINC BINDING;

DIMERIZATION; TRANSCRIPTION; ZINC;

TRANSCRIPTION FACTORS;

DNA BINDING PROTEIN; EARLY B CELL FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR REL; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTO-ONCOGENE PROTEINS C-REL; STRUCTURAL HOMOLOGY, PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; ZINC;

EID: 77956223490     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C110.150482     Document Type: Article

References (37)

1. Hagman, J., Belanger, C., Travis, A., Turck, C. W., and Grosschedl, R. (1993) Genes Dev. 7, 760-773
2. Wang, M. M., and Reed, R. R. (1993) Nature 364, 121-126
3. Hagman, J., Gutch, M. J., Lin, H., and Grosschedl, R. (1995) EMBO J. 14, 2907-2916
4. Travis, A., Hagman, J., Hwang, L., and Grosschedl, R. (1993) Mol. Cell. Biol. 13, 3392-3400
5. Akerblad, P., Lind, U., Liberg, D., Bamberg, K., and Sigvardsson, M. (2002) Mol. Cell. Biol. 22, 8015-8025
6. Kieslinger, M., Folberth, S., Dobreva, G., Dorn, T., Croci, L., Erben, R., Consalez, G. G., and Grosschedl, R. (2005) Dev. Cell 9, 757-767
7. Dubois, L., and Vincent, A. (2001) Mech. Dev. 108, 3-12
8. Wang, S. S., Tsai, R. Y., and Reed, R. R. (1997) J. Neurosci. 17, 4149-4158
9. Gräslund, S., Sagemark, J., Berglund, H., Dahlgren, L. G., Flores, A., Hammarström, M., Johansson, I., Kotenyova, T., Nilsson, M., Nordlund, P., and Weigelt, J. (2008) Protein Expr. Purif. 58, 210-221
10. Kabsch, W. (2010) Acta Crystallogr. D Biol. Crystallogr. 66, 125-132
11. Leslie, A. G. W. (1992) Joint CCP4 + ESF-EAMCB Newsletter on Protein Crystallography, Volume 26, Daresbury Laboratory, Warrington, UK
12. Collaborative Computational Project Number 4 (1994) Acta Crystallogr. D Biol. Crystallogr. 50, 760-763
13. Terwilliger, T. (2004) J. Synchrotron Radiat. 11, 49-52
14. Schneider, T. R., and Sheldrick, G. M. (2002) Acta Crystallogr. D Biol. Crystallogr. 58, 1772-1779
15. McCoy, A. J., Grosse-Kunstleve, R. W., Adams, P. D., Winn, M. D., Storoni, L. C., and Read, R. J. (2007) J. Appl. Crystallogr. 40, 658-674
16. Vagin, A., and Teplyakov, A. (2010) Acta Crystallogr. D Biol. Crystallogr. 66, 22-25
17. Cowtan, K. (2006) Acta Crystallogr. D Biol. Crystallogr. 62, 1002-1011
18. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. D Biol. Crystallogr. 53, 240-255
19. Adams, P. D., Afonine, P. V., Bunkóczi, G., Chen, V. B., Davis, I. W., Echols, N., Headd, J. J., Hung, L. W., Kapral, G. J., Grosse-Kunstleve, R. W., McCoy, A. J., Moriarty, N. W., Oeffner, R., Read, R. J., Richardson, D. C., Richardson, J. S., Terwilliger, T. C., and Zwart, P. H. (2010) Acta Crystallogr. D Biol. Crystallogr. 66, 213-221
20. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
21. Holm, L., Kääriäinen, S., Rosenström, P., and Schenkel, A. (2008) Bioinformatics 24, 2780-2781
22. Potterton, L., McNicholas, S., Krissinel, E., Gruber, J., Cowtan, K., Emsley, P., Murshudov, G. N., Cohen, S., Perrakis, A., and Noble, M. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2288-2294
23. Dominguez, C., Boelens, R., and Bonvin, A. M. (2003) J. Am. Chem. Soc. 125, 1731-1737
24. Fields, S., Ternyak, K., Gao, H., Ostraat, R., Akerlund, J., and Hagman, J. (2008) Mol. Immunol. 45, 3786-3796
25. Patel, K., Kumar, A., and Durani, S. (2007) Biochim. Biophys. Acta 1774, 1247-1253
26. Kleywegt, G. J. (1999) J. Mol. Biol. 285, 1887-1897
27. Bork, P., Doerks, T., Springer, T. A., and Snel, B. (1999) Trends Biochem. Sci. 24, 261-263
28. Mott, H. R., Nietlispach, D., Hopkins, L. J., Mirey, G., Camonis, J. H., and Owen, D. (2003) J. Biol. Chem. 278, 17053-17059
29. Krissinel, E., and Henrick, K. (2007) J. Mol. Biol. 372, 774-797
30. Bouché, N., Scharlat, A., Snedden, W., Bouchez, D., and Fromm, H. (2002) J. Biol. Chem. 277, 21851-21861
31. Daburon, V., Mella, S., Plouhinec, J. L., Mazan, S., Crozatier, M., and Vincent, A. (2008) BMC Evol. Biol. 8, 131
32. Dornan, D., Shimizu, H., Burch, L., Smith, A. J., and Hupp, T. R. (2003) Mol. Cell. Biol. 23, 8846-8861
33. Zhao, F., McCarrick-Walmsley, R., Akerblad, P., Sigvardsson, M., and Kadesch, T. (2003) Mol. Cell. Biol. 23, 3837-3846
34. Stroud, J. C., Lopez-Rodriguez, C., Rao, A., and Chen, L. (2002) Nat. Struct. Biol. 9, 90-94
35. LaPorte, S. L., Juo, Z. S., Vaclavikova, J., Colf, L. A., Qi, X., Heller, N. M., Keegan, A. D., and Garcia, K. C. (2008) Cell 132, 259-272
36. Nam, Y., Sliz, P., Song, L., Aster, J. C., and Blacklow, S. C. (2006) Cell 124, 973-983
37. Smith, E. M., Akerblad, P., Kadesch, T., Axelson, H., and Sigvardsson, M. (2005) Blood 106, 1995-2001