Levetiracetam-induced seizure aggravation associated with continuous spikes and waves during slow sleep in children with refractory epilepsies

Epileptic Disorders

Volumn 12, Issue 2, 2010, Pages 146-150

  Caraballo, Roberto H ^a   Cersósimo, Ricardo ^a   De Los Santos, Cecilia ^a  

^a HOSPITAL DE PEDIATRÍA PROF DR JUAN P GARRAHAN   (Argentina)

Author keywords

Aggravation; Continuous spikes and waves during slow sleep; Dravet syndrome; Levetiracetam; Negative myoclonus

Indexed keywords

CARBAMAZEPINE; CLOBAZAM; ETIRACETAM; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; TOPIRAMATE; VALPROIC ACID; ANTICONVULSIVE AGENT; DRUG DERIVATIVE; PIRACETAM;

CASE REPORT; CHILD; CLINICAL FEATURE; DISEASE EXACERBATION; DRUG INDUCED DISEASE; DRUG RESPONSE; DRUG WITHDRAWAL; EEG ABNORMALITY; EPILEPTIC STATE; FEMALE; FOCAL EPILEPSY; GAIT DISORDER; HUMAN; MALE; MENTAL DEFICIENCY; MYOCLONUS; NEUROLOGIC EXAMINATION; NOTE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SCHOOL CHILD; SEIZURE; SEVERE MYOCLONIC EPILEPSY IN INFANCY; SLOW WAVE SLEEP; SPIKE WAVE; THROMBOCYTOPENIA; TONIC CLONIC SEIZURE; ARTICLE; CHEMICALLY INDUCED DISORDER; DRUG COMBINATION; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; EVOKED RESPONSE; GRAND MAL EPILEPSY; MYOCLONUS EPILEPSY; SLEEP; SYNDROME;

ANTICONVULSANTS; CHILD; DRUG THERAPY, COMBINATION; ELECTROENCEPHALOGRAPHY; EPILEPSIES, MYOCLONIC; EPILEPSIES, PARTIAL; EPILEPSY, TONIC-CLONIC; EVOKED POTENTIALS; FEMALE; HUMANS; MALE; PIRACETAM; SEIZURES; SLEEP; SYNDROME;

EID: 77956193510     PISSN: 12949361     EISSN: 19506945     Source Type: Journal    
DOI: 10.1684/epd.2010.0305     Document Type: Note

References (12)

1. Aeby A, Pozanski N, Verheulpen D, Wetzburger C Van Bogaert P. Levetiracetam efficacy in epileptic syndromes with continuous spikes-and-waves during sleep: experience in 12 cases. Epilepsia 2005; 46: 1937-42. (Pubitemid 44922004)
2. Berkovic SF, Knowlton RC, Leroy RF, Schierman J, Falter U. The Levetiracetam N01057 Study Group. Placebo controlled study of levetiracetam in idiopathic generalized epilepsy. Neurology 2007; 69: 1751-60.
3. Brodie MJ, Perucca E, Ryvlin P, Ben-Menachen E, Meencke HL. The Levetiracetam Monotherapy Study Group. Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology 2007; 68: 402-8.
4. Capovilla G, Beccaria F, Cagdas S, Montagnini A, Segala R, Paganelli D. Efficacy of levetiracetam in pharmacoresistant continuous spikes and waves during slow sleep. Acta Neurologica Scandinavica 2004; 110: 144-7. (Pubitemid 39141283)
5. Caraballo R, Fontana E, Michelizza B, et al. Carbamazepine inducing atypical absences, drop-spells and continuous spike and waves during slow sleep (CSWSS). Boll Lega It Epil 1989; 66/67: 379-81. (Pubitemid 20054082)
6. Cerminara C, Montanaro ML, Curatolo P, Seri S. Lamotrigine-induced seizure aggravation and negative myoclonus in idiopathic rolandic epilepsy. Neurology 2004; 63: 373-5. (Pubitemid 38971149)
7. Glauser TA, Ayala R, Elterman RD, et al. N159 Study Group. Double-blind placebo-controlled trial of adjunctive levetiracetam in paediatric partial seizures. Neurology 2006; 66: 1654-60.
8. Grosso S, Balestri M, Bartolo RM, et al. Oxcarbazepine and atypical evolution of benign idiopathic focal epilepsy of childhood. Eur J Neurol 2003; 13: 1142-5.
9. Guerrini R, Belmonte A, Strumia S, Hirsch E. Exacerbation of epileptic negative myoclonus by carbamazepine or phenobarbital in children with atypical benign rolandic epilepsy. Epilepsia 1995; 36 (Suppl. 3): S65.
10. Montenegro MA, Guerreiro MM. Electrical status epilepticus of sleep in association with Topiramate. Epilepsia 2002; 43: 1436-40. (Pubitemid 35365005)
11. Nakken KO, Ericsson AS, Lossius R, et al. A paradoxical effect of levetiracetam may be seen in both children and adults with refractory epilepsy. Seizure 2003; 12: 42-6. (Pubitemid 36113762)
12. Prats JM, Garaizar C, Garcia Nieto ML, Madoz P. Antiepileptic drugs and atypical evolution of idiopathic partial epilepsy. Pediatr Neurol 1998; 18: 402-6. (Pubitemid 28308706)