Significant impairment of left atrial function in patients with cardioembolic stroke caused by paroxysmal atrial fibrillation

Internal Medicine

Volumn 49, Issue 16, 2010, Pages 1727-1732

  Taguchi, Yoshiharu ^a   Takashima, Shutaro ^a   Hirai, Tadakazu ^b   Fukuda, Nobuyuki ^b   Ohara, Kazumasa ^b   Nakagawa, Keiko ^b   Inoue, Hiroshi ^b   Tanaka, Kortaro ^b  

^a TOYAMA UNIVERSITY HOSPITAL   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Cardioembolic stroke; Left atrial function; Paroxysmal atrial fibrillation; Transesophageal echocardiography

Indexed keywords

AGED; ARTICLE; BLOOD FLOW VELOCITY; BRAIN ISCHEMIA; CARDIOEMBOLIC STROKE; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; FEMALE; HEART ATRIUM FIBRILLATION; HEART ATRIUM FUNCTION; HEART LEFT ATRIUM; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HUMAN; HYPERTENSION; INTRACARDIAC THROMBOSIS; MALE; SINUS RHYTHM; STROKE; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TRANSTHORACIC ECHOCARDIOGRAPHY;

AGED; AGED, 80 AND OVER; ATRIAL FIBRILLATION; ATRIAL FUNCTION, LEFT; ECHOCARDIOGRAPHY, TRANSESOPHAGEAL; FEMALE; HEART FUNCTION TESTS; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; STROKE; THROMBOEMBOLISM;

EID: 77956193136     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.49.3580     Document Type: Article

References (21)

1. Kimura K, Minematsu K, Yamaguchi T. Atrial fibrillation as a predictive factor for severe stroke and early death in 15,831 patients with acute ischaemic stroke. J Neurol Neurosurg Psychiatry 76: 679-683, 2005.
2. Marini C, De Ssntis F, Sacco S, et al. Contribution of atrial fibrillation to incidence and outcome of ischemic stroke: results from a population-based study. Stroke 36: 1115-1119, 2005.
3. Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med 146: 857-867, 2007.
4. Singer DE, Albers GW, Dalen JE, Go AS, Halperin JL, Manning WJ. Antithrombotic therapy in atrial fibrillation: the seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126: 429S-456S, 2004.
5. Abdon NJ, Zettervall O, Carlson J, et al. Is occult atrial disorder a frequent cause of non-hemorrhagic stroke? Long-term ECG in 86 patients. Stroke 13: 832-837, 1982.
6. Koudstaal PJ, van Gijn J, Klootwijk AP, van der Meche FG, Kappelle LJ. Holter monitoring in patients with transient and focal ischemic attacks of the brain. Stroke 17: 192-195, 1986.
7. Rem JA, Hachinski VC, Boughner DR, Barnett HJ. Value of cardiac monitoring and echocardiography in TIA and stroke patients. Stroke 16: 950-956, 1985.
8. Schaer B, Zellweger M, Corn T, Kaiser CA, Osswald S. Value of routine Holter monitoring for the detection of paroxysmal atrial fibrillation in patients with cerebral ischemic events. Stroke 35: e68-e70, 2004.
9. Todo K, Moriwaki H, Saito K, Naritomi H. Frequent premature atrial contractions in stroke of undetermined etiology. Eur Neurol 61: 285-288, 2009.
10. Fatkin D, Kelly RP, Fenely MP. Relations between left atrial appendage blood flow velocity, spontaneous echocardiographic contrast and thromboembolic risk in vivo. J Am Coll Cardiol 23: 961-969, 1994.
11. Kwon HM, Park JH, Kim JM, Yoon BW. Mild left ventricular dysfunction is associated with thrombogenicity in cardioembolic stroke. Eur Neurol 56: 217-221, 2006.
12. Kamp O, Verhorst PMJ, Welling RC, Visser CA. Importance of left atrial appendage flow as a predictor of thromboembolic events in patients with atrial fibrillation. Eur Heart J 20: 979-985, 1999.
13. Pollick C, Taylor D. Assessment of left atrial appendage function by transesophageal echocardiography: implications for the development of thrombus. Circulation 84: 223-231, 1991.
14. Shinokawa N, Hirai T, Takashima S, et al. A transesophageal echocardiographic study on risk factors for stroke in elderly patients with atrial fibrillation: A comparison with younger patients. Chest 120: 840-846, 2001.
15. Liao J, Khalid Z, Scallan C, Morillo C, O'Donnell M. Noninvasive cardiac monitoring for detecting paroxysmal atrial fibrillation or flutter after acute ischemic stroke: a systematic review. Stroke 38: 2935-2940, 2007.
16. Wallmann D, Tüller D, Wustmann K, et al. Frequent atrial premature beats predict paroxysmal atrial fibrillation in stroke patients: an opportunity for a new diagnostic strategy. Stroke 38: 2292-2294, 2007.
17. Naya T, Yukiiri K, Hosomi N, et al. Brain natriuretic peptide as a surrogate marker for cardioembolic stroke with paroxysmal atrial fibrillation. Cerebrovasc Dis 26: 434-440, 2008.
18. Ohara K, Hirai T, Fukuda N, et al. Relation of left atrial blood stasis to clinical risk factors in atrial fibrillation. Int J Cardio 132: 210-215, 2009.
19. Kaneko K, Hirono O, Fatema K, et al. Direct evidence that sustained dysfunction of left atrial appendage contributes to the occurrence of cardiogenic brain embolism in patients with paroxysmal atrial fibrillation. Intern Med 42: 1077-1083, 2003.
20. Ohara K, Inoue H, Nozawa T, et al. Accumulation of risk factors enhances the prothrombotic state in atrial fibrillation. Int J Cardiol 126: 316-321, 2008.
21. Staszewski J, Brodacki B, Tomczykiewicz K, Kotowicz J, Stepien A. Strokes in paroxysmal atrial fibrillation have more favorable outcome than in permanent atrial fibrillation. Acta Neurol Scand 119: 325-331, 2009.