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Volumn 29, Issue 9, 2010, Pages 1021-1029

Use of tumor necrosis factor α inhibitors in hepatitis B surface antigen-positive patients: A literature review and potential mechanisms of action

Author keywords

Ankylosing spondylitis; Crohn's disease; Hepatitis B virus; Psoriasis; Rheumatoid arthritis; Tumor necrosis factor

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; CERTOLIZUMAB PEGOL; ETANERCEPT; GOLIMUMAB; HEPATITIS B SURFACE ANTIGEN; INFLIXIMAB; METHOTREXATE; SALAZOSULFAPYRIDINE; TUMOR NECROSIS FACTOR ALPHA;

EID: 77956189825     PISSN: 07703198     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10067-010-1523-2     Document Type: Article
Times cited : (103)

References (86)
  • 1
    • 16644398295 scopus 로고    scopus 로고
    • Serious infections associated with anticytokine therapies in the rheumatic diseases
    • 10.1177/0885066604267854 15523118
    • JT Giles JM Bathon 2004 Serious infections associated with anticytokine therapies in the rheumatic diseases J Intensive Care Med 19 320 334 10.1177/0885066604267854 15523118
    • (2004) J Intensive Care Med , vol.19 , pp. 320-334
    • Giles, J.T.1    Bathon, J.M.2
  • 2
    • 0035846326 scopus 로고    scopus 로고
    • Tuberculosis associated with infliximab, a tumor necrosis factor α-neutralizing agent
    • 10.1056/NEJMoa011110 11596589
    • J Keane S Gershon RP Wise, et al. 2001 Tuberculosis associated with infliximab, a tumor necrosis factor α-neutralizing agent N Engl J Med 345 1098 1103 10.1056/NEJMoa011110 11596589
    • (2001) N Engl J Med , vol.345 , pp. 1098-1103
    • Keane, J.1    Gershon, S.2    Wise, R.P.3
  • 3
    • 54849146600 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • 10.1056/NEJMra0801644 18832247
    • JL Dienstag 2008 Hepatitis B virus infection N Engl J Med 359 14 1486 1500 10.1056/NEJMra0801644 18832247
    • (2008) N Engl J Med , vol.359 , Issue.14 , pp. 1486-1500
    • Dienstag, J.L.1
  • 4
    • 71449093991 scopus 로고    scopus 로고
    • Review article: Chronic viral infection in the anti-tumour necrosis factor therapy era in inflammatory bowel disease
    • 10.1111/j.1365-2036.2009.04112.x
    • MJ Shale CH Seow CS Coffin, et al. 2009 Review article: chronic viral infection in the anti-tumour necrosis factor therapy era in inflammatory bowel disease Aliment Pharmacol Ther 31 20 34 10.1111/j.1365-2036.2009.04112.x
    • (2009) Aliment Pharmacol Ther , vol.31 , pp. 20-34
    • Shale, M.J.1    Seow, C.H.2    Coffin, C.S.3
  • 5
    • 84855635249 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research Accessed8August2009
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research (2008) Drugs@FDA: Adalimumab Label Information. http://www.accessdata.fda.gov/ drugsatfda-docs/label/2008/125057s114lbl.pdf. Accessed 8 August 2009
    • (2008) Drugs@FDA: Adalimumab Label Information
  • 6
    • 84855629997 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research Accessed8August2009
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research (2008) Drugs@FDA: Certolizumab Label Information. http://www.accessdata.fda. gov/drugsatfda-docs/label/2008/125160s000lbl.pdf. Accessed 8 August 2009
    • (2008) Drugs@FDA: Certolizumab Label Information
  • 7
    • 84855626581 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research Accessed8August2009
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research (2008) Drugs@FDA: Etanercept Label Information. http://www.accessdata.fda.gov/ drugsatfda-docs/label/2008/103795s5359lbl.pdf. Accessed 8 August 2009
    • (2008) Drugs@FDA: Etanercept Label Information
  • 8
    • 84855629727 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research Accessed8August2009
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research (2009) Drugs@FDA: Golimumab Label Information. http://www.accessdata.fda.gov/ drugsatfda-docs/label/2009/125289s000lbl.pdf. Accessed 8 August 2009
    • (2009) Drugs@FDA: Golimumab Label Information
  • 9
    • 84855629727 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research Accessed8August2009
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research (2009) Drugs@FDA: Infliximab Label Information. http://www.accessdata.fda.gov/ drugsatfda-docs/label/2009/103772s5234lbl.pdf. Accessed 8 August 2009
    • (2009) Drugs@FDA: Infliximab Label Information
  • 10
    • 67349155253 scopus 로고    scopus 로고
    • Spondyloarthropathy and chronic B hepatitis. Effect of anti-TNF therapy
    • 10.1016/j.jbspin.2008.11.005
    • D Wendling V Di Martino C Prati, et al. 2009 Spondyloarthropathy and chronic B hepatitis. Effect of anti-TNF therapy Jt Bone Spine 76 308 311 10.1016/j.jbspin.2008.11.005
    • (2009) Jt Bone Spine , vol.76 , pp. 308-311
    • Wendling, D.1    Di Martino, V.2    Prati, C.3
  • 11
    • 20244379866 scopus 로고    scopus 로고
    • Reactivation of a latent precore mutant hepatitis B virus related chronic hepatitis during infliximab treatment for severe spondyloarthropathy
    • 10.1136/ard.2004.031187 15834064
    • D Wendling B Auge D Bettinger, et al. 2005 Reactivation of a latent precore mutant hepatitis B virus related chronic hepatitis during infliximab treatment for severe spondyloarthropathy Ann Rheum Dis 64 788 789 10.1136/ard.2004.031187 15834064
    • (2005) Ann Rheum Dis , vol.64 , pp. 788-789
    • Wendling, D.1    Auge, B.2    Bettinger, D.3
  • 12
    • 36749011910 scopus 로고    scopus 로고
    • Lamivudine resistance and exacerbation of hepatitis B in infliximab-treated Crohn's disease patient
    • 10.1002/ibd.20202 17712837
    • M Esteve C Loras F González-Huix 2007 Lamivudine resistance and exacerbation of hepatitis B in infliximab-treated Crohn's disease patient Inflamm Bowel Dis 13 11 1450 1451 10.1002/ibd.20202 17712837
    • (2007) Inflamm Bowel Dis , vol.13 , Issue.11 , pp. 1450-1451
    • Esteve, M.1    Loras, C.2    González-Huix, F.3
  • 13
    • 4344614501 scopus 로고    scopus 로고
    • Chronic hepatitis B reactivation following infliximab therapy in Crohn's disease patients: Need for primary prophylaxis
    • 10.1136/gut.2004.040675 15306601
    • M Esteve C Saro F González-Huix, et al. 2004 Chronic hepatitis B reactivation following infliximab therapy in Crohn's disease patients: need for primary prophylaxis Gut 53 1363 1365 10.1136/gut.2004.040675 15306601
    • (2004) Gut , vol.53 , pp. 1363-1365
    • Esteve, M.1    Saro, C.2    González-Huix, F.3
  • 14
    • 67149147430 scopus 로고    scopus 로고
    • Use of tumor necrosis factor-α-blocking agents in hepatitis B virus-positive patients: Reports of 3 cases and review of the literature
    • 10.3899/jrheum.081246 19447932
    • S Zingarelli M Frassi C Bazzani, et al. 2009 Use of tumor necrosis factor-α-blocking agents in hepatitis B virus-positive patients: reports of 3 cases and review of the literature J Rheumatol 36 6 1188 1194 10.3899/jrheum.081246 19447932
    • (2009) J Rheumatol , vol.36 , Issue.6 , pp. 1188-1194
    • Zingarelli, S.1    Frassi, M.2    Bazzani, C.3
  • 15
    • 57149139723 scopus 로고    scopus 로고
    • Prophylaxis and therapy of HBV infection in 20 patients treated with disease modifying antirheumatic drugs or with biological agents for rheumatic diseases
    • 18432322
    • S Zingarelli P Airò M Frassi, et al. 2008 Prophylaxis and therapy of HBV infection in 20 patients treated with disease modifying antirheumatic drugs or with biological agents for rheumatic diseases Reumatismo 60 1 22 27 18432322
    • (2008) Reumatismo , vol.60 , Issue.1 , pp. 22-27
    • Zingarelli, S.1    Airò, P.2    Frassi, M.3
  • 16
    • 33749587637 scopus 로고    scopus 로고
    • Safety of anti-TNF-α therapy in rheumatoid arthritis and spondyloarthropathies with concurrent B or C chronic hepatitis
    • 10.1093/rheumatology/kel123 16603583
    • CH Roux O Brocq V Breuil, et al. 2006 Safety of anti-TNF-α therapy in rheumatoid arthritis and spondyloarthropathies with concurrent B or C chronic hepatitis Rheumatology 45 1294 1297 10.1093/rheumatology/kel123 16603583
    • (2006) Rheumatology , vol.45 , pp. 1294-1297
    • Roux, C.H.1    Brocq, O.2    Breuil, V.3
  • 17
    • 40649094547 scopus 로고    scopus 로고
    • Short-term course of chronic hepatitis B and C under treatment with etanercept associated with different disease modifying antirheumatic drugs without antiviral prophylaxis
    • 18203328
    • DU Cansu T Kalifoglu C Korkmaz 2008 Short-term course of chronic hepatitis B and C under treatment with etanercept associated with different disease modifying antirheumatic drugs without antiviral prophylaxis J Rheumatol 35 421 424 18203328
    • (2008) J Rheumatol , vol.35 , pp. 421-424
    • Cansu, D.U.1    Kalifoglu, T.2    Korkmaz, C.3
  • 18
    • 47249104803 scopus 로고    scopus 로고
    • Use of tumor necrosis factor-α inhibitors in patients with chronic hepatitis B infection
    • 10.1016/j.semarthrit.2007.10.011 18221983
    • MB Carroll MI Bond 2008 Use of tumor necrosis factor-α inhibitors in patients with chronic hepatitis B infection Semin Arthritis Rheum 38 3 208 217 10.1016/j.semarthrit.2007.10.011 18221983
    • (2008) Semin Arthritis Rheum , vol.38 , Issue.3 , pp. 208-217
    • Carroll, M.B.1    Bond, M.I.2
  • 19
    • 67349101230 scopus 로고    scopus 로고
    • Use of tumor necrosis factor-α (TNF-α) antagonists infliximab, etanercept, and adalimumab in patients with concurrent rheumatoid arthritis and hepatitis B or hepatitis C: A retrospective record review of 11 patients
    • 10.1007/s10067-009-1149-4 19291350
    • S Li PP Kaur V Chan 2009 Use of tumor necrosis factor-α (TNF-α) antagonists infliximab, etanercept, and adalimumab in patients with concurrent rheumatoid arthritis and hepatitis B or hepatitis C: a retrospective record review of 11 patients Clin Rheumatol 28 787 791 10.1007/s10067-009-1149-4 19291350
    • (2009) Clin Rheumatol , vol.28 , pp. 787-791
    • Li, S.1    Kaur, P.P.2    Chan, V.3
  • 20
    • 47349090572 scopus 로고    scopus 로고
    • Histological evaluation of liver in two rheumatoid arthritis patients with chronic hepatitis B and C treated with TNF-alpha blockade: Case reports
    • 10.1007/s10067-008-0896-y 18521652
    • PP Kaur VC Chan SN Berney 2008 Histological evaluation of liver in two rheumatoid arthritis patients with chronic hepatitis B and C treated with TNF-alpha blockade: case reports Clin Rheumatol 27 1069 1071 10.1007/s10067-008-0896-y 18521652
    • (2008) Clin Rheumatol , vol.27 , pp. 1069-1071
    • Kaur, P.P.1    Chan, V.C.2    Berney, S.N.3
  • 21
    • 33645094377 scopus 로고    scopus 로고
    • Subfulminant hepatitis B after infliximab in Crohn's disease: Need for HBV-screening?
    • 16521231
    • G Millonig M Kern O Ludwiczek, et al. 2006 Subfulminant hepatitis B after infliximab in Crohn's disease: need for HBV-screening? World J Gastroenterol 12 974 976 16521231
    • (2006) World J Gastroenterol , vol.12 , pp. 974-976
    • Millonig, G.1    Kern, M.2    Ludwiczek, O.3
  • 22
    • 0038504830 scopus 로고    scopus 로고
    • Fulminant hepatitis after infliximab in a patient with hepatitis B virus treated for an adult onset Still's disease
    • 12858469
    • M Michel C Duvoux C Hezode, et al. 2003 Fulminant hepatitis after infliximab in a patient with hepatitis B virus treated for an adult onset Still's disease J Rheumatol 30 1624 1625 12858469
    • (2003) J Rheumatol , vol.30 , pp. 1624-1625
    • Michel, M.1    Duvoux, C.2    Hezode, C.3
  • 23
    • 0037532694 scopus 로고    scopus 로고
    • Hepatitis B reactivation in a chronic hepatitis B surface antigen carrier with rheumatoid arthritis treated with infliximab and low dose methotrexate
    • 10.1136/ard.62.7.686 12810441
    • P Ostuni C Botsios L Punzi, et al. 2003 Hepatitis B reactivation in a chronic hepatitis B surface antigen carrier with rheumatoid arthritis treated with infliximab and low dose methotrexate Ann Rheum Dis 62 686 687 10.1136/ard.62.7.686 12810441
    • (2003) Ann Rheum Dis , vol.62 , pp. 686-687
    • Ostuni, P.1    Botsios, C.2    Punzi, L.3
  • 24
    • 0346057892 scopus 로고    scopus 로고
    • Infliximab therapy for rheumatic diseases in patients with chronic hepatitis B or C
    • 14705228
    • O Oniankitan C Duvous D Challine, et al. 2004 Infliximab therapy for rheumatic diseases in patients with chronic hepatitis B or C J Rheumatol 31 107 109 14705228
    • (2004) J Rheumatol , vol.31 , pp. 107-109
    • Oniankitan, O.1    Duvous, C.2    Challine, D.3
  • 25
    • 20044386121 scopus 로고    scopus 로고
    • Infliximab Therapy for Crohn's disease in patient with chronic hepatitis B
    • 10.1007/s10620-005-1295-8 15712655
    • Y Ueno S Tanaka M Shimamoto, et al. 2005 Infliximab Therapy for Crohn's disease in patient with chronic hepatitis B Dig Dis Sci 50 163 166 10.1007/s10620-005-1295-8 15712655
    • (2005) Dig Dis Sci , vol.50 , pp. 163-166
    • Ueno, Y.1    Tanaka, S.2    Shimamoto, M.3
  • 26
    • 23644453655 scopus 로고    scopus 로고
    • Improvement of renal function and disappearance of hepatitis B virus DNA in a patient with rheumatoid arthritis and renal amyloidosis following treatment with infliximab
    • 10.1002/art.21216 16052569
    • MG Anelli DD Torres C Manno, et al. 2005 Improvement of renal function and disappearance of hepatitis B virus DNA in a patient with rheumatoid arthritis and renal amyloidosis following treatment with infliximab Arthritis Rheum 52 2519 2520 10.1002/art.21216 16052569
    • (2005) Arthritis Rheum , vol.52 , pp. 2519-2520
    • Anelli, M.G.1    Torres, D.D.2    Manno, C.3
  • 27
    • 4644254334 scopus 로고    scopus 로고
    • Infliximab therapy in a patient with Crohn's disease and chronic hepatitis B virus infection
    • 10.1097/00054725-200409000-00035
    • G-S MdV F Gomez-Camacho A Poyato-Gonzalez, et al. 2004 Infliximab therapy in a patient with Crohn's disease and chronic hepatitis B virus infection Inflamm Bowel Dis 10 5 701 702 10.1097/00054725-200409000-00035
    • (2004) Inflamm Bowel Dis , vol.10 , Issue.5 , pp. 701-702
    • Mdv, G.-S.1    Gomez-Camacho, F.2    Poyato-Gonzalez, A.3
  • 28
    • 34247592817 scopus 로고    scopus 로고
    • Occult hepatitis B and infliximab-induced HBV reactivation
    • 10.1002/ibd.20035 17206687
    • S Madonia A Orlando D Scimeca, et al. 2007 Occult hepatitis B and infliximab-induced HBV reactivation Inflamm Bowel Dis 13 4 508 10.1002/ibd.20035 17206687
    • (2007) Inflamm Bowel Dis , vol.13 , Issue.4 , pp. 508
    • Madonia, S.1    Orlando, A.2    Scimeca, D.3
  • 29
    • 63249126294 scopus 로고    scopus 로고
    • Anti-TNF-α therapy for rheumatoid arthritis among patients with chronic hepatitis B infection
    • 10.1093/rheumatology/kep003
    • H Robinson K Walker-Bone 2009 Anti-TNF-α therapy for rheumatoid arthritis among patients with chronic hepatitis B infection Rheumatology 48 450 451 10.1093/rheumatology/kep003
    • (2009) Rheumatology , vol.48 , pp. 450-451
    • Robinson, H.1    Walker-Bone, K.2
  • 30
    • 34250729244 scopus 로고    scopus 로고
    • Long-term anti-TNFα therapy for ankylosing spondylitis in two patients with chronic HBV infection
    • 10.1007/s10067-006-0392-1 16865308
    • GT Sakellariou I Chatzigiannis 2007 Long-term anti-TNFα therapy for ankylosing spondylitis in two patients with chronic HBV infection Clin Rheumatol 26 950 952 10.1007/s10067-006-0392-1 16865308
    • (2007) Clin Rheumatol , vol.26 , pp. 950-952
    • Sakellariou, G.T.1    Chatzigiannis, I.2
  • 31
    • 36749054694 scopus 로고    scopus 로고
    • Fulminant hepatic failure in chronic hepatitis B on withdrawal of corticosteroids, azathioprine and infliximab for Crohn's disease
    • 10.1002/ibd.20216 17600380
    • C Colbert A Chavarria C Berkelhammer 2007 Fulminant hepatic failure in chronic hepatitis B on withdrawal of corticosteroids, azathioprine and infliximab for Crohn's disease Inflamm Bowel Dis 13 1453 1454 10.1002/ibd.20216 17600380
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1453-1454
    • Colbert, C.1    Chavarria, A.2    Berkelhammer, C.3
  • 32
    • 46949085913 scopus 로고    scopus 로고
    • Reactivation of hepatitis B in a patient with Crohn's disease treated using infliximab
    • 10.1007/s00535-008-2165-x 18592158
    • K Ojiro M Naganuma H Ebinuma, et al. 2008 Reactivation of hepatitis B in a patient with Crohn's disease treated using infliximab J Gastroenterol 43 397 401 10.1007/s00535-008-2165-x 18592158
    • (2008) J Gastroenterol , vol.43 , pp. 397-401
    • Ojiro, K.1    Naganuma, M.2    Ebinuma, H.3
  • 33
    • 33746494001 scopus 로고    scopus 로고
    • Hepatitis B virus (HBV) reactivation with immunosuppressive therapy in rheumatic diseases: Assessment and preventive strategies
    • 10.1136/ard.2005.043257 16627542
    • LH Calabrese NN Zein D Vassilopoulos 2006 Hepatitis B virus (HBV) reactivation with immunosuppressive therapy in rheumatic diseases: assessment and preventive strategies Ann Rheum Dis 65 983 989 10.1136/ard.2005.043257 16627542
    • (2006) Ann Rheum Dis , vol.65 , pp. 983-989
    • Calabrese, L.H.1    Zein, N.N.2    Vassilopoulos, D.3
  • 34
    • 0034678409 scopus 로고    scopus 로고
    • Intrahepatic T cells in hepatitis B: Viral control versus liver cell injury
    • 10.1084/jem.191.8.1263 10770794
    • B Rehermann 2000 Intrahepatic T cells in hepatitis B: viral control versus liver cell injury J Exp Med 191 1263 1268 10.1084/jem.191.8.1263 10770794
    • (2000) J Exp Med , vol.191 , pp. 1263-1268
    • Rehermann, B.1
  • 35
    • 33745219475 scopus 로고    scopus 로고
    • Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-α gene promoter polymorphisms
    • 10.1111/j.1440-1746.2006.04304.x
    • JY Cheong SW Cho IL Hwang, et al. 2006 Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-α gene promoter polymorphisms J Gastro Hepatology 21 1163 1169 10.1111/j.1440-1746.2006.04304.x
    • (2006) J Gastro Hepatology , vol.21 , pp. 1163-1169
    • Cheong, J.Y.1    Cho, S.W.2    Hwang, I.L.3
  • 36
    • 0037256512 scopus 로고    scopus 로고
    • Cytokine gene polymorphisms in patients infected with hepatitis B virus
    • 10.1111/j.1572-0241.2003.07179.x 12526950
    • Z Ben-Ari E Mor O Papo, et al. 2003 Cytokine gene polymorphisms in patients infected with hepatitis B virus Am J Gastroenterol 98 144 150 10.1111/j.1572-0241.2003.07179.x 12526950
    • (2003) Am J Gastroenterol , vol.98 , pp. 144-150
    • Ben-Ari, Z.1    Mor, E.2    Papo, O.3
  • 37
    • 0031594577 scopus 로고    scopus 로고
    • A tumour necrosis factor-alpha (TNF-α) promoter polymorphism is associated with chronic hepatitis B infection
    • 10.1046/j.1365-2249.1998.00534.x 9528902
    • T Höhler A Kruger G Gerken, et al. 1998 A tumour necrosis factor-alpha (TNF-α) promoter polymorphism is associated with chronic hepatitis B infection Clin Exp Immunol 111 579 582 10.1046/j.1365-2249.1998. 00534.x 9528902
    • (1998) Clin Exp Immunol , vol.111 , pp. 579-582
    • Höhler, T.1    Kruger, A.2    Gerken, G.3
  • 38
    • 33745146860 scopus 로고    scopus 로고
    • Association of-238G/A and -857C/T polymorphisms of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection
    • 16827185
    • HQ Li Z Li Y Liu, et al. 2006 Association of-238G/A and -857C/T polymorphisms of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection Biomed Environ Sci 19 2 133 136 16827185
    • (2006) Biomed Environ Sci , vol.19 , Issue.2 , pp. 133-136
    • Li, H.Q.1    Li, Z.2    Liu, Y.3
  • 39
    • 26244433900 scopus 로고    scopus 로고
    • Association of polymorphism of tumor necrosis factor-alpha gene promoter region with outcome of hepatitis B virus infection
    • 16127755
    • HQ Li Z Li Y Liu 2005 Association of polymorphism of tumor necrosis factor-alpha gene promoter region with outcome of hepatitis B virus infection World J Gastroenterol 11 33 5213 5217 16127755
    • (2005) World J Gastroenterol , vol.11 , Issue.33 , pp. 5213-5217
    • Li, H.Q.1    Li, Z.2    Liu, Y.3
  • 40
    • 0141841617 scopus 로고    scopus 로고
    • Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection
    • 10.1093/hmg/ddg262 12915457
    • YJ Kim HS Lee JH Yoon, et al. 2003 Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection Hum Mol Genet 12 19 2541 2546 10.1093/hmg/ddg262 12915457
    • (2003) Hum Mol Genet , vol.12 , Issue.19 , pp. 2541-2546
    • Kim, Y.J.1    Lee, H.S.2    Yoon, J.H.3
  • 41
    • 33747186637 scopus 로고    scopus 로고
    • Association of TNF-alpha promoter polymorphisms with the outcomes of hepatitis B virus infection in Chinese Han population
    • 10.1111/j.1365-2893.2006.00731.x 16907849
    • T Du XH Guo XL Zhu, et al. 2006 Association of TNF-alpha promoter polymorphisms with the outcomes of hepatitis B virus infection in Chinese Han population J Viral Hepat 13 9 618 624 10.1111/j.1365-2893.2006.00731.x 16907849
    • (2006) J Viral Hepat , vol.13 , Issue.9 , pp. 618-624
    • Du, T.1    Guo, X.H.2    Zhu, X.L.3
  • 42
    • 0029997619 scopus 로고    scopus 로고
    • Activations of the tumor necrosis factor-α system in the liver in chronic hepatitis B virus infection
    • 8677942
    • JWS Fang WW Shen A Meager, et al. 1996 Activations of the tumor necrosis factor-α system in the liver in chronic hepatitis B virus infection Am J Gastroenterol 91 748 753 8677942
    • (1996) Am J Gastroenterol , vol.91 , pp. 748-753
    • Fang, J.W.S.1    Shen, W.W.2    Meager, A.3
  • 43
    • 0034678409 scopus 로고    scopus 로고
    • Intrahepatic T cells in hepatitis B: Viral control versus liver cell injury
    • 10.1084/jem.191.8.1263 10770794
    • B Rehermann 2000 Intrahepatic T cells in hepatitis B: viral control versus liver cell injury J Exp Med 191 1263 1268 10.1084/jem.191.8.1263 10770794
    • (2000) J Exp Med , vol.191 , pp. 1263-1268
    • Rehermann, B.1
  • 44
    • 0030787584 scopus 로고    scopus 로고
    • Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor α
    • 10.1073/pnas.94.16.8744 9238048
    • F Su RJ Schneider 1997 Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor α Proc Natl Acad Sci USA 94 8744 8749 10.1073/pnas.94.16.8744 9238048
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8744-8749
    • Su, F.1    Schneider, R.J.2
  • 45
    • 0037213545 scopus 로고    scopus 로고
    • CD8+ T cells mediate viral clearance and disease pathogenesis during aucte hepatitis B virus infection
    • 10.1128/JVI.77.1.68-76.2003 12477811
    • R Thimme S Wieland C Steiger, et al. 2003 CD8+ T cells mediate viral clearance and disease pathogenesis during aucte hepatitis B virus infection J Virol 77 68 76 10.1128/JVI.77.1.68-76.2003 12477811
    • (2003) J Virol , vol.77 , pp. 68-76
    • Thimme, R.1    Wieland, S.2    Steiger, C.3
  • 46
    • 35548983363 scopus 로고    scopus 로고
    • Molecular virology of hepatitis B virus for clinicians
    • 10.1016/j.cld.2007.08.002 17981225
    • TM Block H Guo JT Guo 2007 Molecular virology of hepatitis B virus for clinicians Clin Liver Dis 11 685 706 10.1016/j.cld.2007.08.002 17981225
    • (2007) Clin Liver Dis , vol.11 , pp. 685-706
    • Block, T.M.1    Guo, H.2    Guo, J.T.3
  • 47
    • 77956191960 scopus 로고    scopus 로고
    • What is the role of cccDNA in chronic HBV infection? Impact on HBV therapy
    • J Petersen M Lutgehetmann T Volz, et al. 2007 What is the role of cccDNA in chronic HBV infection? Impact on HBV therapy Hepatol Rev 4 9 13
    • (2007) Hepatol Rev , vol.4 , pp. 9-13
    • Petersen, J.1    Lutgehetmann, M.2    Volz, T.3
  • 48
    • 34249945560 scopus 로고    scopus 로고
    • Formation of hepatitis B virus covalently closed circular DNA: Removal of genome-linked protein
    • 10.1128/JVI.02721-06 17409153
    • W Gao J Hu 2007 Formation of hepatitis B virus covalently closed circular DNA: removal of genome-linked protein J Virol 81 6164 6174 10.1128/JVI.02721-06 17409153
    • (2007) J Virol , vol.81 , pp. 6164-6174
    • Gao, W.1    Hu, J.2
  • 49
    • 20444505037 scopus 로고    scopus 로고
    • Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy
    • 10.1053/j.gastro.2005.03.009
    • JJ Sung ML Wong S Bowden 2005 Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy Gastroenterol 128 1890 1897 10.1053/j.gastro.2005.03.009
    • (2005) Gastroenterol , vol.128 , pp. 1890-1897
    • Sung, J.J.1    Wong, M.L.2    Bowden, S.3
  • 50
    • 13844250599 scopus 로고    scopus 로고
    • New insight on HBV persistence from the study of intrahepatic viral cccDNA
    • 10.1016/j.jhep.2004.12.015 15710212
    • F Zoulim 2005 New insight on HBV persistence from the study of intrahepatic viral cccDNA J Hepatol 42 302 308 10.1016/j.jhep.2004.12.015 15710212
    • (2005) J Hepatol , vol.42 , pp. 302-308
    • Zoulim, F.1
  • 51
    • 0034678435 scopus 로고    scopus 로고
    • The role of virus-specific CD8+ cells in liver damage and viral control during persistent hepatitis B virus infection
    • 10.1084/jem.191.8.1269 10770795
    • MK Maini C Boni CK Lee, et al. 2000 The role of virus-specific CD8+ cells in liver damage and viral control during persistent hepatitis B virus infection J Exp Med 191 1269 1281 10.1084/jem.191.8.1269 10770795
    • (2000) J Exp Med , vol.191 , pp. 1269-1281
    • Maini, M.K.1    Boni, C.2    Lee, C.K.3
  • 52
    • 0028609979 scopus 로고
    • Hepatic expression of tumour necrosis factor-alpha in chronic hepatitis B virus infection
    • 10.1136/jcp.47.12.1112 7876386
    • MJ Hussain JY Lau R Williams, et al. 1994 Hepatic expression of tumour necrosis factor-alpha in chronic hepatitis B virus infection J Clin Pathol 47 12 1112 1115 10.1136/jcp.47.12.1112 7876386
    • (1994) J Clin Pathol , vol.47 , Issue.12 , pp. 1112-1115
    • Hussain, M.J.1    Lau, J.Y.2    Williams, R.3
  • 53
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B virus infection-natural history and clinical consequences
    • 10.1056/NEJMra031087 15014185
    • D Ganem AM Prince 2004 Hepatitis B virus infection-natural history and clinical consequences N Engl J Med 350 1118 1129 10.1056/NEJMra031087 15014185
    • (2004) N Engl J Med , vol.350 , pp. 1118-1129
    • Ganem, D.1    Prince, A.M.2
  • 54
    • 36049033413 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha 308.2 polymorphism is associated with advanced hepatic fibrosis and higher risk for hepatocellular carcinoma
    • 10.1593/neo.07781 18030367
    • JE Jeng JF Tsai LY Chuang, et al. 2007 Tumor necrosis factor-alpha 308.2 polymorphism is associated with advanced hepatic fibrosis and higher risk for hepatocellular carcinoma Neoplasia 9 11 987 992 10.1593/neo.07781 18030367
    • (2007) Neoplasia , vol.9 , Issue.11 , pp. 987-992
    • Jeng, J.E.1    Tsai, J.F.2    Chuang, L.Y.3
  • 55
    • 84855622876 scopus 로고    scopus 로고
    • Remicade website Accessed7April2010
    • Remicade website (2010) Centocor. http://www.remicade.com/remicade/ global/index.html. Accessed 7 April 2010
    • (2010) Centocor
  • 56
    • 38549176118 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
    • 10.1016/j.pharmthera.2007.10.001 18155297
    • D Tracey L Klareskog EH Sasso, et al. 2008 Tumor necrosis factor antagonist mechanisms of action: a comprehensive review Pharmacol Ther 117 244 279 10.1016/j.pharmthera.2007.10.001 18155297
    • (2008) Pharmacol Ther , vol.117 , pp. 244-279
    • Tracey, D.1    Klareskog, L.2    Sasso, E.H.3
  • 57
    • 33750608851 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonists: Different kinetics and/or mechanisms of action may explain differences in the risk for developing granulomatous infection
    • 10.1016/j.semarthrit.2006.02.001 16884970
    • DE Furst O Beenhouwer 2006 Tumor necrosis factor antagonists: different kinetics and/or mechanisms of action may explain differences in the risk for developing granulomatous infection Semin Arthritis Rheum 36 3 159 167 10.1016/j.semarthrit.2006.02.001 16884970
    • (2006) Semin Arthritis Rheum , vol.36 , Issue.3 , pp. 159-167
    • Furst, D.E.1    Beenhouwer, O.2
  • 58
    • 0037998263 scopus 로고    scopus 로고
    • Differentiating the new rheumatoid arthritis biologic therapies
    • 10.1097/01.RHU.0000062513.64012.1d 17041440
    • AL Weaver 2003 Differentiating the new rheumatoid arthritis biologic therapies J Clin Rheumatol 9 2 99 114 10.1097/01.RHU.0000062513.64012.1d 17041440
    • (2003) J Clin Rheumatol , vol.9 , Issue.2 , pp. 99-114
    • Weaver, A.L.1
  • 59
    • 2442590862 scopus 로고    scopus 로고
    • New drugs for rheumatoid arthritis
    • 10.1056/NEJMra032906 15152062
    • NJ Olsen CM Stein 2004 New drugs for rheumatoid arthritis N Engl J Med 350 21 2167 2179 10.1056/NEJMra032906 15152062
    • (2004) N Engl J Med , vol.350 , Issue.21 , pp. 2167-2179
    • Olsen, N.J.1    Stein, C.M.2
  • 60
    • 84855630969 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research Accessed8August2009
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research (2004) Drugs@FDA: Infliximab Label Information. http://www.accessdata.fda.gov/ drugsatfda-docs/label/2004/103772-5077-lbl.pdf. Accessed 8 August 2009
    • (2004) Drugs@FDA: Infliximab Label Information
  • 61
    • 51549119395 scopus 로고    scopus 로고
    • A PEGylated Fab' fragment against tumor necrosis factor for the treatment of Crohn's disease
    • 10.2165/00063030-200822050-00005 18778114
    • T Bourne G Fossati A Nesbitt 2008 A PEGylated Fab' fragment against tumor necrosis factor for the treatment of Crohn's disease Biodrugs 22 5 331 337 10.2165/00063030-200822050-00005 18778114
    • (2008) Biodrugs , vol.22 , Issue.5 , pp. 331-337
    • Bourne, T.1    Fossati, G.2    Nesbitt, A.3
  • 62
    • 43949126520 scopus 로고    scopus 로고
    • Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor α-expressing cells: Comparison among infliximab, etanercept, and adalimumab
    • 10.1002/art.23447 18438840
    • H Mitoma T Horiuchi H Tsukamoto, et al. 2008 Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor α-expressing cells: comparison among infliximab, etanercept, and adalimumab Arthritis Rheum 58 5 1248 1257 10.1002/art.23447 18438840
    • (2008) Arthritis Rheum , vol.58 , Issue.5 , pp. 1248-1257
    • Mitoma, H.1    Horiuchi, T.2    Tsukamoto, H.3
  • 63
    • 67449162094 scopus 로고    scopus 로고
    • New tumor necrosis factor inhibitors for rheumatoid arthritis: Are there benefits from extending choice?
    • 10.1136/ard.2008.105940 19435722
    • DL Scott A Cope 2009 New tumor necrosis factor inhibitors for rheumatoid arthritis: are there benefits from extending choice? Ann Rheum Dis 68 6 767 769 10.1136/ard.2008.105940 19435722
    • (2009) Ann Rheum Dis , vol.68 , Issue.6 , pp. 767-769
    • Scott, D.L.1    Cope, A.2
  • 64
    • 33645064086 scopus 로고    scopus 로고
    • In vitro complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity by the anti-TNF agents adalimumab, etanercept, infliximab, and certolizumab pegol (CDP870): 807
    • G Fossati A Nesbitt 2005 In vitro complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity by the anti-TNF agents adalimumab, etanercept, infliximab, and certolizumab pegol (CDP870): 807 Am J Gastro 100 supp 1 S299
    • (2005) Am J Gastro , vol.100 , Issue.SUPPL. 1 , pp. 299
    • Fossati, G.1    Nesbitt, A.2
  • 65
    • 33746773036 scopus 로고    scopus 로고
    • Tumor-necrosis-factor blockers: Differential effects on mycobacterial immunity
    • 10.1086/505430 16845632
    • OY Saliu C Sofer D Stein, et al. 2006 Tumor-necrosis-factor blockers: differential effects on mycobacterial immunity J Infect Dis 194 486 492 10.1086/505430 16845632
    • (2006) J Infect Dis , vol.194 , pp. 486-492
    • Saliu, O.Y.1    Sofer, C.2    Stein, D.3
  • 66
    • 67650096563 scopus 로고    scopus 로고
    • Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy
    • 10.1002/art.24632 19565495
    • F Tubach D Salmon P Ravaud, et al. 2009 Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy Arthritis Rheum 60 7 1884 1894 10.1002/art.24632 19565495
    • (2009) Arthritis Rheum , vol.60 , Issue.7 , pp. 1884-1894
    • Tubach, F.1    Salmon, D.2    Ravaud, P.3
  • 67
    • 67749102110 scopus 로고    scopus 로고
    • The infectious profiles of anti-tumor necrosis factor agents in a Thai population: A retrospective study a the university-based hospital
    • 10.1111/j.1756-185X.2009.01393.x 20374328
    • P Suwannalai P Auethavekiat U Udomsubpayakul, et al. 2009 The infectious profiles of anti-tumor necrosis factor agents in a Thai population: a retrospective study a the university-based hospital Int J Rheum Dis 12 2 118 124 10.1111/j.1756-185X.2009.01393.x 20374328
    • (2009) Int J Rheum Dis , vol.12 , Issue.2 , pp. 118-124
    • Suwannalai, P.1    Auethavekiat, P.2    Udomsubpayakul, U.3
  • 68
    • 38749119069 scopus 로고    scopus 로고
    • Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis
    • 10.1136/ard.2007.072967 17644554
    • T Takeuchi Y Tatsuki Y Nogami, et al. 2008 Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis Ann Rheum Dis 67 2 189 194 10.1136/ard.2007.072967 17644554
    • (2008) Ann Rheum Dis , vol.67 , Issue.2 , pp. 189-194
    • Takeuchi, T.1    Tatsuki, Y.2    Nogami, Y.3
  • 69
    • 67449102437 scopus 로고    scopus 로고
    • Postmarketing surveillance of the safety and effectiveness of etanercept in Japan
    • 10.3899/jrheum.080791 19332630
    • T Koike M Harigai S Inokuma, et al. 2009 Postmarketing surveillance of the safety and effectiveness of etanercept in Japan J Rheum 36 5 898 906 10.3899/jrheum.080791 19332630
    • (2009) J Rheum , vol.36 , Issue.5 , pp. 898-906
    • Koike, T.1    Harigai, M.2    Inokuma, S.3
  • 70
    • 84855632802 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research Accessed17March2010
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research (1999) Drugs@FDA: Infliximab Product Approval Information. < http://www.accessdata.fda.gov/drugsatfda-docs/appletter/1999/inflcen111099L.htm. Accessed 17 March 2010
    • (1999) Drugs@FDA: Infliximab Product Approval Information
  • 71
    • 84855619466 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research Accessed17March2010
    • U.S. Food and Drug Administration Center for Drug Evaluation and Research (2002) Drugs@FDA: Etanercept Product Approval Information-Licensing Action. http://www.accessdata.fda.gov/drugsatfda-docs/appletter/2002/etanimm011502L.htm. Accessed 17 March 2010
    • (2002) Drugs@FDA: Etanercept Product Approval Information-Licensing Action
  • 72
    • 33746652902 scopus 로고    scopus 로고
    • Hepatitis B and C virus infections and anti-tumor necrosis factor-α therapy: Guidelines for clinical approach
    • 10.1111/j.1440-1746.2006.04559.x 16911678
    • DM Nathan PW Angus PR Gibson 2006 Hepatitis B and C virus infections and anti-tumor necrosis factor-α therapy: guidelines for clinical approach J Gastroenterol Hepatol 21 1366 1371 10.1111/j.1440-1746.2006.04559.x 16911678
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 1366-1371
    • Nathan, D.M.1    Angus, P.W.2    Gibson, P.R.3
  • 73
    • 66149166191 scopus 로고    scopus 로고
    • Hepatitis B: The virus and disease
    • 10.1002/hep.22881 19399811
    • TJ Liang 2009 Hepatitis B: the virus and disease Hepatology 49 5 Suppl S13 S21 10.1002/hep.22881 19399811
    • (2009) Hepatology , vol.49 , Issue.5 SUPPL.
    • Liang, T.J.1
  • 74
    • 45349090538 scopus 로고    scopus 로고
    • American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis
    • 10.1002/art.23721 18512708
    • KG Saag GG Teng NM Patkar, et al. 2008 American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis Arthritis Rheum 59 6 762 784 10.1002/art.23721 18512708
    • (2008) Arthritis Rheum , vol.59 , Issue.6 , pp. 762-784
    • Saag, K.G.1    Teng, G.G.2    Patkar, N.M.3
  • 75
    • 14044260093 scopus 로고    scopus 로고
    • Update on the British Society for Rheumatology guidelines for prescribing TNFalpha blockers in adults with rheumatoid arthritis (update of previous guidelines of April 2001)
    • 10.1093/rheumatology/keh464 15637039
    • J Ledingham C Deighton 2005 Update on the British Society for Rheumatology guidelines for prescribing TNFalpha blockers in adults with rheumatoid arthritis (update of previous guidelines of April 2001) Rheumatology 44 2 157 163 10.1093/rheumatology/keh464 15637039
    • (2005) Rheumatology , vol.44 , Issue.2 , pp. 157-163
    • Ledingham, J.1    Deighton, C.2
  • 76
    • 84855627934 scopus 로고    scopus 로고
    • British Society of Rheumatology Accessed15August2009
    • British Society of Rheumatology. "BSR Guidelines." http://www.rheumatology.org.uk/guidelines/. Accessed 15 August 2009
    • BSR Guidelines
  • 77
    • 33644855102 scopus 로고    scopus 로고
    • American Gastroenterologic Association Institute medical position statement on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease
    • 10.1053/j.gastro.2006.01.047 16530531
    • GR Lichtenstein MT Abreu R Cohen, et al. 2006 American Gastroenterologic Association Institute medical position statement on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease Gastroenterology 130 935 939 10.1053/j.gastro.2006.01.047 16530531
    • (2006) Gastroenterology , vol.130 , pp. 935-939
    • Lichtenstein, G.R.1    Abreu, M.T.2    Cohen, R.3
  • 78
    • 4344602852 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults
    • 10.1136/gut.2004.043372 15306569
    • MJ Carter AJ Lobo SPL Travis 2004 Guidelines for the management of inflammatory bowel disease in adults Gut 53 Supp V v1 v16 10.1136/gut.2004. 043372 15306569
    • (2004) Gut , vol.53 , Issue.SUPPL. V
    • Carter, M.J.1    Lobo, A.J.2    Travis, S.P.L.3
  • 79
    • 33748444790 scopus 로고    scopus 로고
    • Problems encountered during anti-tumor necrosis factor therapy
    • 10.1016/j.berh.2006.06.002
    • SB Desai DE Furst 2006 Problems encountered during anti-tumor necrosis factor therapy Best Prac & Res Clin Rheum 20 4 757 790 10.1016/j.berh.2006. 06.002
    • (2006) Best Prac & Res Clin Rheum , vol.20 , Issue.4 , pp. 757-790
    • Desai, S.B.1    Furst, D.E.2
  • 80
    • 34948850781 scopus 로고    scopus 로고
    • Risks of immunosuppressive therapies including biologic agents in patients with rheumatic diseases and co-existing chronic viral infections
    • 10.1097/BOR.0b013e3282f05b63 17917544
    • D Vassilopoulos LH Calabrese 2007 Risks of immunosuppressive therapies including biologic agents in patients with rheumatic diseases and co-existing chronic viral infections Curr Opin Rheumatol 19 619 625 10.1097/BOR. 0b013e3282f05b63 17917544
    • (2007) Curr Opin Rheumatol , vol.19 , pp. 619-625
    • Vassilopoulos, D.1    Calabrese, L.H.2
  • 81
  • 82
    • 33749627330 scopus 로고    scopus 로고
    • How to modulate inflammatory cytokines in liver disease
    • 10.1111/j.1478-3231.2006.01339.x 17032402
    • H Tilg A Kaser AR Moschen 2006 How to modulate inflammatory cytokines in liver disease Liver Int 26 1029 1039 10.1111/j.1478-3231.2006.01339.x 17032402
    • (2006) Liver Int , vol.26 , pp. 1029-1039
    • Tilg, H.1    Kaser, A.2    Moschen, A.R.3
  • 83
    • 33746494001 scopus 로고    scopus 로고
    • Hepatitis B virus (HBV) reactivation with immunosuppressive therapy in rheumatic diseases: Assessment and preventive strategies
    • 10.1136/ard.2005.043257 16627542
    • LH Calabrese NN Zein D Vassilopoulos 2006 Hepatitis B virus (HBV) reactivation with immunosuppressive therapy in rheumatic diseases: assessment and preventive strategies Ann Rheum Dis 65 983 989 10.1136/ard.2005.043257 16627542
    • (2006) Ann Rheum Dis , vol.65 , pp. 983-989
    • Calabrese, L.H.1    Zein, N.N.2    Vassilopoulos, D.3
  • 84
    • 33745219475 scopus 로고    scopus 로고
    • Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-α gene promoter polymorphisms
    • 10.1111/j.1440-1746.2006.04304.x
    • JY Cheong SW Cho IL Hwang, et al. 2006 Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-α gene promoter polymorphisms J Gastro Hepatology 21 1163 1169 10.1111/j.1440-1746.2006.04304.x
    • (2006) J Gastro Hepatology , vol.21 , pp. 1163-1169
    • Cheong, J.Y.1    Cho, S.W.2    Hwang, I.L.3
  • 85
    • 0034110026 scopus 로고    scopus 로고
    • Chronic viral hepatitis and the human genome
    • 10.1053/he.2000.4316 10733534
    • CL Thio DL Thomas M Carrington 2000 Chronic viral hepatitis and the human genome Hepatology 31 819 827 10.1053/he.2000.4316 10733534
    • (2000) Hepatology , vol.31 , pp. 819-827
    • Thio, C.L.1    Thomas, D.L.2    Carrington, M.3
  • 86
    • 84984555343 scopus 로고    scopus 로고
    • Hepatitis B e antigen and the risk of hepatocellular carcinoma
    • 10.1056/NEJMoa013215 12124405
    • HI Yang SN Lu YF Liaw, et al. 2002 Hepatitis B e antigen and the risk of hepatocellular carcinoma N Engl J Med 347 3 168 174 10.1056/NEJMoa013215 12124405
    • (2002) N Engl J Med , vol.347 , Issue.3 , pp. 168-174
    • Yang, H.I.1    Lu, S.N.2    Liaw, Y.F.3


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