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Volumn 45, Issue 10, 2010, Pages 4615-4621

Design, synthesis and qualitative structure-activity evaluations of novel hexahydropyrano[3,2-c][1,2]diazepin-3(4H)-one and tetrahydropyrano[3,2-b]pyrrol- 2(1H)-one derivatives as anticancer agents

(1) Al Tel, Taleb H a

a UNIVERSITY OF SHARJAH (United Arab Emirates)

Author keywords

ketoesters; Achmatowicz reaction; Anticancer agents; Hexahydropyrano 3,2 c 1,2 diazepin 3(4H) one; Pyrenones; Tetrahydropyrano 3,2 b pyrrol 2(1H) one

Indexed keywords

1 (1H INDOL 3 YL) 5 METHOXY 3A PHENYL 3,3A,5,6 TETRAHYDROPYRANO[3,2 B]PYRROL 2(1H) ONE; 1 (1H INDOL 5 YL) 5 METHOXY 3A PHENYL 3,3A,5,6 TETRAHYDROPYRANO[3,2 B]PYRROL 2(1H) ONE; 1 (3,5 DICHLOROPHENYL) 5 METHOXY 3A PHENYL 3,3A,5,6 TETRAHYDROPYRANO[3,2 B]PYRROL 2(1H) ONE; 1 (3,5 DIMETHOXYPHENYL) 5 METHOXY 3A PHENYL 3,3A,5,6 TETRAHYDROPYRANO[3,2 B]PYRROL 2(1H) ONE; 2 (1H INDOL 3 YL) 7 METHOXY 5A PHENYL 1,2,5,5A,7,8 HEXAHYDROPYRANO[3,2 C][1,2]DIAZEPIN 3(4H) ONE; 2 (3,5 DICHLOROPHENYL) 7 METHOXY 5A PHENYL 1,2,5,5A,7,8 HEXAHYDROPYRANO[3,2 C][1,2]DIAZEPIN 3(4H) ONE; 2 (3,5 DIMETHOXYPHENYL) 7 METHOXY 5A PHENYL 1,2,5,5A,7,8 HEXAHYDROPYRANO[3,2 C][1,2]DIAZEPIN 3(4H) ONE; 5 METHOXY 1 (4 NITROPHENYL) 3A PHENYL 3,3A,5,6 TETRAHYDROPYRANO[3,2 B]PYRROL 2(1H) ONE; 5 METHOXY 3A PHENYL 1 (PYRIDIN 2 YL) 3,3A,5,6 TETRAHYDROPYRANO[3,2 B]PYRROL 2(1H) ONE; 5 METHOXY 3A PHENYL 1 4 TOLYL 3,3A,5,6 TETRAHYDROPYRANO[3,2 B]PYRROL 2(1H) ONE; 7 METHOXY 2 (4 METHOXYPHENYL) 5A PHENYL 1,2,5,5A,7,8 HEXAHYDROPYRANO[3,2 C][1,2]DIAZEPIN 3(4H) ONE; 7 METHOXY 2 (4 NITROPHENYL) 5A PHENYL 1,2,5,5A,7,8 HEXAHYDROPYRANO[3,2 C][1,2]DIAZEPIN 3(4H) ONE; 7 METHOXY 5A PHENYL 2 (PYRIDIN 2 YL) 1,2,5,5A,7,8 HEXAHYDROPYRANO[3,2 C][1,2]DIAZEPIN 3(4H) ONE; 7 METHOXY 5A PHENYL 2 4 TOLYL 1,2,5,5A,7,8 HEXAHYDROPYRANO[3,2 C][1,2]DIAZEPIN 3(4H) ONE; ANTINEOPLASTIC AGENT; HEXAHYDROPYRANO[3,2 C][1,2]DIAZEPIN 3(4H) ONE DERIVATIVE; TETRAHYDROPYRANO[3,2 B]PYRROL 2(1H) ONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CYCLIZATION; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HUMANS; NEOPLASMS; PYRANS; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77956187950 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2010.07.026 Document Type: Article

Times cited : (8)

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