Synthesis, characterization, antiamoebic activity and cytotoxicity of novel series of pyrazoline derivatives bearing quinoline tail

European Journal of Medicinal Chemistry

Volumn 45, Issue 10, 2010, Pages 4669-4675

  Hayat, Faisal ^a   Salahuddin, Attar ^a   Umar, Sadiq ^b   Azam, Amir ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^b HAMDARD UNIVERSITY   (India)

Author keywords

Entamoeba histolytica; MTT assay; Pyrazoline derivatives

Indexed keywords

1 (4,5 DIHYDRO 3 PHENYL 5 P TOLYLPYRAZOL 1 YL) 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 (4,5 DIHYDRO 3,5 DIPHENYLPYRAZOL 1 YL) 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 [3 (4 BROMOPHENYL) 4,5 DIHYDRO 5 (4 METHOXYPHENYL)PYRAZOL 1 YL] 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 [3 (4 BROMOPHENYL) 4,5 DIHYDRO 5 PHENYLPYRAZOL 1 YL] 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 [3 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 (4 METHOXYPHENYL)PYRAZOL 1 YL] 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 [3 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 P TOLYLPYRAZOL 1 YL] 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 [3 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 PHENYLPYRAZOL 1 YL] 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 [4, 5 DIHYDRO 5 (4 METHOXYPHENYL) 3 PHENYLPYRAZOL 1 YL] 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 [5 (2 CHLOROPHENYL) 4,5 DIHYDRO 3 PHENYLPYRAZOL 1 YL] 2 (QUINOLIN 8 YLOXY)ETHANONE; 1 [5 (3 CHLOROPHENYL) 4,5 DIHYDRO 3 PHENYLPYRAZOL 1 YL] 2 (QUINOLIN 8 YLOXY)ETHANONE; ANTIAMEBIC AGENT; METRONIDAZOLE; PYRAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; ENTAMOEBA HISTOLYTICA; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMEBICIDES; CELL LINE, TUMOR; CELL SURVIVAL; ENTAMOEBA HISTOLYTICA; ENTAMOEBIASIS; HUMANS; PYRAZOLES; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77956185782     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.07.028     Document Type: Article

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