Functionalised polysiloxanes as injectable, in situ curable accommodating intraocular lenses

Biomaterials

Volumn 31, Issue 32, 2010, Pages 8153-8163

  Hao, Xiaojuan ^a,c   Jeffery, Justine L ^a   Wilkie, John S ^a   Meijs, Gordon F ^a   Clayton, Anthony B ^a   Watling, Jason D ^a,c   Ho, Arthur ^c   Fernandez, Viviana ^b   Acosta, Carolina ^b   Yamamoto, Hideo ^b   Aly, Mohamed G M ^b   Parel, Jean Marie ^b,c   Hughes, Timothy C ^a  

^a CSIRO   (Australia)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Accommodating; In situ curable; Injectable; Intraocular lens; Macromonomer; Polysiloxane

Indexed keywords

ACCOMMODATING; IN-SITU; INJECTABLE; INTRAOCULAR; MACROMONOMER; POLYSILOXANES;

BIOCOMPATIBILITY; CONTACT LENSES; CURING; GELS; HYDROSILYLATION; IRRADIATION; MECHANICAL PROPERTIES; MONOMERS; OPTICAL INSTRUMENTS; POLYMERS; SILANES; SILICONES; TOLUENE; VISCOSITY;

INTRAOCULAR LENSES;

2,4,6,8 TETRAMETHYLCYCLOTETRASILOXANE; HEXAETHYLDISILOXANE; METHACRYLIC ACID; MONOMER; OCTAMETHYLCYCLOTETRASILOXANE; POLYOLPREPOLYMER 2; POLYSILOXANE; TOLUENE; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

AGED; ARTICLE; BIOCATALYST; BIOCOMPATIBILITY; BIOSYNTHESIS; CHEMICAL STRUCTURE; CONCENTRATION PROCESS; FLOW MEASUREMENT; FLUORESCENCE IN SITU HYBRIDIZATION; HYDROSILYLATION; IRRADIATION; LENS CAPSULE; LENS IMPLANT; LIGHT SCATTERING; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; REFRACTION INDEX; RING OPENING METATHESIS POLYMERIZATION; ULTRAVIOLET SPECTROSCOPY; VISCOMETRY;

ACCOMMODATION, OCULAR; ANIMALS; BIOCOMPATIBLE MATERIALS; CORNEA; INJECTIONS; LENS, CRYSTALLINE; LENSES, INTRAOCULAR; MACACA FASCICULARIS; MATERIALS TESTING; RABBITS; SILOXANES;

ORYCTOLAGUS CUNICULUS; PRIMATES;

EID: 77956184650     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.07.065     Document Type: Article

References (66)

1. Glasser A. Restoration of accommodation. Curr Opin Ophthalmol 2006, 17(1):12-18.
2. Charman W.N. The eye in focus: accommodation and presbyopia. Clin Exp Optom 2008, 91(3):207-225.
3. Glasser A. Restoration of accommodation: surgical options for correction of presbyopia. Clin Exp Optom 2008, 91(3):279-295.
4. Weeber H.A., van der Heijde R.G.L. On the relationship between lens stiffness and accommodative amplitude. Exp Eye Res 2007, 85:602-607.
5. Charman W.N. Restoring accommodation: a dream or an approaching reality?. Ophthalmic Physiol Opt 2005, 25(1):1-6.
6. Robman L., Taylor H. External factors in the development of cataract. Eye 2005, 19(10):1074-1082.
7. de Groot J.H., van Beijma F.J., Haitjema H.J., Dillingham K.A., Hodd K.A., Koopmans S.A., et al. Injectable intraocular lens materials based upon hydrogels. Biomacromolecules 2001, 2(3):628-634.
8. Yoo M.K., Choi Y.J., Lee J.H., Wee W.R., Cho C.S. Injectable intraocular lens using hydrogels. J Drug Deliv Sci Technol 2007, 17(1):81-85.
9. Fisher R.F. Elastic constants of human lens. J Physiol 1971, 212(1):147.
10. Heys K.R., Cram S.L., Truscott R.J.W. Massive increase in the stiffness of the human lens nucleus with age: the basis for presbyopia?. Mol Vis 2004, 10(114):956-963.
11. Weeber H.A., Eckert G., Soergel F., Meyer C.H., Pechhold W., van der Heijde R.G.L. Dynamic mechanical properties of human lenses. Exp Eye Res 2005, 80(3):425-434.
12. Koeppl C., Findl O., Menapace R., Kriechbaum K., Wirtitsch M., Buehl W., et al. Pilocarpine-induced shift of an accommodating intraocular lens: AT-45 crystalens. J Cataract Refract Surg 2005, 31(7):1290-1297.
13. Ho A., Manns F., Pham T., Parel J.M. Predicting the performance of accommodating intraocular lenses using ray tracing. J Cataract Refract Surg 2006, 32(1):129-136.
14. Findl O., Kriechbaum K., Menapace R., Koeppl C., Sacu S., Wirtitsch M., et al. Laser interferometric assessment of pilocarpine-induced movement of an accommodating intraocular lens - a randomized trial. Ophthalmology 2004, 111(8):1515-1521.
15. Stachs O., Schneider H., Beck R., Guthoff R. Pharmacological-induced haptic changes and the accommodative performance in patients with the AT-45 accommodative IOL. J Refract Surg 2006, 22(2):145-150.
16. Dogru M., Honda R., Omoto M., Toda I., Fujishima H., Arai H., et al. Early visual results with the ICU accommodating intraocular lens. J Cataract Refract Surg 2005, 31(5):895-902.
17. Kuchle M., Nguyen N.X., Langenbucher A., Gusek-Schneider G.C., Seitz B. Two years experience with the new accommodative 1 CU intraocular lens. Ophthalmologe 2002, 99(11):820-824.
18. Kessler J. Experiments in refilling lens. Arch Ophthalmol 1964, 71(3):412.
19. Bennett A.G. Variable and progressive lenses. Manuf Opt Intern 1973, 25:759-762.
20. Fowler C.W., Pateras E.S. Liquid-crystal lens review. Ophthalmic Physiol Opt 1990, 10(2):186-194.
21. Charman W.N. Can diffractive liquid-crystal lenses aid presbyopes. Ophthalmic Physiol Opt 1993, 13(4):427-429.
22. Pateras E.S., Fowler C.W., Chandrinos A.B. Deformable spectacle lenses. Ophthalmic Physiol Opt 1993, 13(1):97-99.
23. Parel J.M., Gelender H., Trefers W.F., Norton E.W.D. Phaco-ersatz - cataract-surgery designed to preserve accommodation. Graefes Arch Clin Exp Ophthalmol 1986, 224(2):165-173.
24. Haefliger E., Parel J.M., Fantes F., Norton E.W.D., Anderson D.R., Forster R.K., et al. Accommodation of an endocapsular silicone lens (phaco-ersatz) in the nonhuman primate. Ophthalmology 1987, 94(5):471-477.
25. Parel J.M., Holden B.A. Accommodating intraocular lenses and lens refilling to restore accommodation. Intraocular lenses in cataract and refractive surgery 2001, 313-324. WB Saunders, Philadelphia PA, [Chapter 27]. D. T Azar, S. Yoo, W. Stark, N. F Azar, R. Pineda (Eds.).
26. Haefliger E., Parel J.M. Accommodation of an endocapsular silicone lens (phaco-ersatz) in the aging rhesus-monkey. J Refract Corneal Surg 1994, 10(5):550-555.
27. Nishi O., Nishi K. Accommodation amplitude after lens refilling with injectable silicone by sealing the capsule with a plug in primates. Arch Ophthalmol 1998, 116(10):1358-1361.
28. Nishi O., Nishi K., Mano C., Ichihara M., Honda T. Lens refilling with injectable silicone in rabbit eyes. J Cataract Refract Surg 1998, 24(7):975-982.
29. Koopmans S.A., Terwee T., Haitjema H.J., Deuring H., van Aarle S., Kooijman A.C. Relation between injected volume and optical parameters in refilled isolated porcine lenses. Ophthalmic Physiol Opt 2004, 24(6):572-579.
30. Swegmark G. Studies with impedance cyclography on human ocular accommodation at different ages. Acta Ophthalmol 1969, 47(5-6):1186.
31. Fisher R.F. Force of contraction of human ciliary muscle during accommodation. J Physiol 1977, 270(1):51.
32. Fisher R.F. Human accommodation and force of contraction of ciliary muscle. Exp Eye Res 1977, 24(1):102.
33. Fisher R.F. The ciliary body in accommodation. Trans Ophthalmol Soc U K 1986, 105:208-219.
34. Strenk S.A., Semmlow J.L., Strenk L.M., Munoz P., Gronlund-Jacob J., DeMarco J.K. Age-related changes in human ciliary muscle and lens: a magnetic resonance imaging study. Invest Ophthalmol Vis Sci 1999, 40(6):1162-1169.
35. Glasser A., Campbell M.C.W. Presbyopia and the optical changes in the human crystalline lens with age. Vision Res 1998, 38(2):209-229.
36. Koopmans S.A., Terwee B., Barkhof J., Haitjema H.J., Kooijman A.C. Polymer refilling of presbyopic human lenses in vitro restores the ability to undergo accommodative changes. Invest Ophthalmol Vis Sci 2003, 44:250-257.
37. Koopmans S.A., Terwee T., Glasser A., Wendt M., Vilipuru A.S., van Kooten T.G., et al. Accommodative lens refilling in rhesus monkeys. Invest Ophthalmol Vis Sci 2006, 47(7):2976-2984.
38. Yonemura K., Villain F., Kiss K., Takesue Y., Parel J.M., Margules G.S. Cross-linked silicone polymers for lens refilling. Invest Ophthalmol Vis Sci 1993, 34(4):1453.
39. van Kooten T.G., Koopmans S., Terwee T., Norrby S., Hooymans J.M.M., Busscher H.J. Development of an accommodating intra-ocular lens - in vitro prevention of re-growth of pig and rabbit lens capsule epithelial cells. Biomaterials 2006, 27(32):5554-5560.
40. Hartman L.C., Bessette R.W., Baier R.E., Meyer A.E., Wirth J. Silicone-rubber temporomandibular-joint (TMJ) meniscal replacements - postimplant histopathologic and material evaluation. J Biomed Mater Res 1988, 22(6):475-484.
41. Nakamura K., Refojo M.F., Crabtree D.V., Pastor J., Leong F.L. Ocular toxicity of low-molecular-weight components of silicone and fluorosilicone oils. Invest Ophthalmol Vis Sci 1991, 32(12):3007-3020.
42. Aliyar H.A., Hamilton P.D., Ravi N. Refilling of ocular lens capsule with copolymeric hydrogel containing reversible disulfide. Biomacromolecules 2005, 6(1):204-211.
43. Parel J.M., Crock G.W., Pericic L.J. The optics of the ophthalmoscope and related instruments. J Phys E 1980, 13(12):1242-1253.
44. Pierscionek B.K., Chan D.Y.C. Refractive-index gradient of human lenses. Optom Vis Sci 1989, 66(12):822-829.
45. Parel J.M., Fernandez V., Billotte C., Denham D.B., Lamar P.D., Rosen A., et al. Accommodation stress-strain relation in human and non-human primate eyes ex-vivo. Invest Ophthalmol Vis Sci 2002, 43:406. Suppl.
46. Parel J.M., Lee W., Lamar P., Acosta A.C., Abri A., Nose I., et al. Manual lens stretching apparatus (MLSA) for rapid analysis of the optical properties of the natural lens, accommodating IOL and refilled lens capsule (phaco-ersatz). Invest Ophthalmol Vis Sci 2004, 45:1724. Suppl.
47. Manns F., Parel J.M., Denham D., Billotte C., Ziebarth N., Borja D., et al. Optomechanical response of human and monkey lenses in a lens stretcher. Invest Ophthalmol Vis Sci 2007, 48(7):3260-3268.
48. Ehrmann K., Ho A., Parel J.M. Biomechanical analysis of the accommodative apparatus in primates. Clin Exp Optom 2008, 91(3):302-312.
49. Fernandez V., Fragoso M.A., Billotte C., Lamar P., Orozco M.A., Dubovy S., et al. Efficacy of various drugs in the prevention of posterior capsule opacification: experimental study of rabbit eyes. J Cataract Refract Surg 2004, 30(12):2598-2605.
50. Tahi H., Chapon P., Hamaoui M., Lee W., Holden B., Parel J.M. Restoring accommodation: surgical technique and preliminary evaluation in rabbits. Ophthalmic technologies IX 1999, 3591A:267-269. SPIE Annu Tech Symp Proc. P.O. Rol, K.M. Joos, F. Manns (Eds.).
51. Abbasi F., Mirzadeh H., Katbab A.A. Modification of polysiloxane polymers for biomedical applications: a review. Polym Int 2001, 50(12):1279-1287.
52. Teng C.J., Weber W.P., Cai G.P. Acid and base catalyzed ring-opening polymerization of 2,2,4,4,6,6-hexamethyl-8,8-diphenylcyclotetrasiloxane. Polymer 2003, 44(15):4149-4155.
53. Cai G.P., Weber W.P. Synthesis and chemical modification of poly(divinylsiloxane). Polymer 2002, 43(6):1753-1759.
54. Teng C.J., Weber W.P., Cai G.P. Anionic and cationic ring-opening polymerization of 2,2,4,4,6,6-hexamethyl-8,8-divinylcyclotetrasiloxane. Macromolecules 2003, 36(14):5126-5130.
55. Silicones. Kirk-othmer encyclopedia of chemical technology 2007, John Wiley & Sons I. 5th ed.
56. Chujo Y., Shishino T., Yamashita Y. Synthesis and application of polymerizable silicone oligomers from water glass. Polym J (Tokyo Jpn) 1984, 16(6):495-504.
57. Duplock S.K., Matisons J.G., Swincer A.G., Warren R.F.O. Synthesis of siloxanes containing reactive side chains. J Inorg Organomet Polym 1991, 1(3):361-375.
58. Marciniec B., Gulinski J., Kopylova L., Maciejewski H., GrundwaldWyspianska M., Lewandowski M. Catalysis of hydrosilylation 31. Functionalization of poly(methylhydro)siloxanes via hydrosilylation of allyl derivatives. Appl Organomet Chem 1997, 11(10-11):843-849.
59. Boutevin B., Guida-Pietrasanta F., Ratsimihety A. Synthesis of photocrosslinkable fluorinated polydimethylsiloxanes: direct introduction of acrylic pendant groups via hydrosilylation. J Polym Sci A Polym Chem 2000, 38(20):3722-3728.
60. Colomines G., Andre S., Andrieu X., Rousseau A., Boutevin B. Synthesis and characterization of ultraviolet-curable fluorinated polydimethylsiloxanes as ultraviolet-transparent coatings for optical fiber gratings. J Appl Polym Sci Symp 2003, 90(8):2021-2026.
61. Quan X. Properties of post-cured siloxane networks. Polym Eng Sci 1989, 29(20):1419-1425.
62. Khan S.A., Plitz I.M., Frantz R.A. In situ technique for monitoring the gelation of UV-curable polymers. Rheol Acta 1992, 31(2):151-160.
63. Verney V., Commereuc S. Molecular evolution of polymers through photoaging: a new UV in situ viscoelastic technique. Macromol Rapid Commun 2005, 26(11):868-873.
64. Reilly M.A., Hamilton P.D., Ravi N. Dynamic multi-arm radial lens stretcher: a robotic analog of the ciliary body. Exp Eye Res 2008, 86(1):157-164.
65. Accommodation and presbyopia 1975, vol. 1. The Professional Press, Chicago, [Chapter 6 Clinical Refraction]. 3rd ed. I.M. Borish (Ed.).
66. Parel J.M., Manns F., Ho A., Holden B. Refractive surgical procedures to restore accommodation. Refractive surgery 2006, 501-510. Mosby Elsevier, Philadelphia PA, [Chapter 40]. 2nd ed. A. Dimitri, G. Damien, H.-X. Thanh (Eds.).