Combined cardiopulmonary assessments with implantable telemetry device in conscious freely moving cynomolgus monkeys

Journal of Pharmacological and Toxicological Methods

Volumn 62, Issue 1, 2010, Pages 6-11

  Authier, S ^a,b   Haefner, Paul ^c   Fournier, S ^a   Troncy, E ^b   Moon, L B ^c  

^a LAB Research Inc   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c Data Sciences International   (United States)

Author keywords

Cynomolgus monkeys; ICH S7A guideline; Impedance; Minute volume; Respiratory rate; Respiratory safety pharmacology; Telemetry; Tidal volume

Indexed keywords

COCAINE; MEDETOMIDINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BODY TEMPERATURE; BREATHING RATE; CARDIOPULMONARY FUNCTION; CONTROLLED STUDY; DRUG SAFETY; ELECTROCARDIOGRAM; FEMALE; HEART RATE; IMPEDANCE; LUNG MINUTE VOLUME; MACACA; NONHUMAN; PHYSICAL ACTIVITY; RESPIRATION DEPRESSION; TELEMETRY; TIDAL VOLUME;

ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ANIMALS; BLOOD PRESSURE; BODY TEMPERATURE; CARDIOGRAPHY, IMPEDANCE; COCAINE; CONSCIOUSNESS; DRUG EVALUATION, PRECLINICAL; ELECTROCARDIOGRAPHY; ELECTRODES, IMPLANTED; FEMALE; HEART RATE; MACACA FASCICULARIS; MEDETOMIDINE; RESPIRATION; RESPIRATORY INSUFFICIENCY; RESPIRATORY MECHANICS; RESPIRATORY RATE; TELEMETRY; TIDAL VOLUME; VASOCONSTRICTOR AGENTS;

ANIMALIA; MACACA FASCICULARIS;

EID: 77956173104     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2010.05.014     Document Type: Article

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