Quick identification of apoptosis inducer from Isodon eriocalyx by a drug discovery platform composed of analytical high-speed counter-current chromatography and the fluorescence-based caspase-3 biosensor detection

Talanta

Volumn 82, Issue 4, 2010, Pages 1521-1527

  Han, Quan Bin ^a,b   Yu, Ting ^c   Lai, Fanny ^a   Zhou, Yan ^a   Feng, Chao ^c   Wang, Wei Na ^d   Fu, Xiao Hui ^d   Lau, Clara Bik San ^a   Luo, Kathy Q ^c   Xu, Hong Xi ^a   Sun, Han Dong ^b   Fung, Kwok Pui ^a   Leung, Ping Chung ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b KUNMING INSTITUTE OF BOTANY   (China)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^d TAUTO Biotech Co Ltd   (China)

Author keywords

Analytical high speed counter current chromatography; Apoptosis inducer; Caspase 3 biosensor; Eriocalyxin B; Isodon eriocalyx

Indexed keywords

BIOSENSORS; CELL DEATH; DRUG PRODUCTS; ENERGY TRANSFER; FORSTER RESONANCE ENERGY TRANSFER; FRACTIONATION; HEXANE; NUCLEAR MAGNETIC RESONANCE; ORGANIC SOLVENTS; PURIFICATION;

ACTIVE INGREDIENTS; CASPASE-3; DRUG CONCENTRATION; HIGH-SPEED COUNTER CURRENT CHROMATOGRAPHY; HIGH-THROUGHPUT SCREENING; ISODON ERIOCALYX; LIQUID SEPARATION; NATURAL PRODUCTS;

LIQUID CHROMATOGRAPHY;

EID: 77956162768     PISSN: 00399140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.talanta.2010.07.036     Document Type: Article

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