Heme oxygenase-1 is the candidate targeting for organ transplantation

Chinese Medical Journal

Volumn 123, Issue 15, 2010, Pages 2128-2134

  Li, Le Ping ^a   Zhang, Li ^a   Peng, Li Pan ^a   Cheng, Li ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

Author keywords

Heme oxyenase 1; Ischaemic reperfusion injury; Transplantation

Indexed keywords

ADENOVIRUS VECTOR; BILIVERDIN; CARBON MONOXIDE; CYCLOSPORIN A; GLUTAMINE; HEME; HEME OXYGENASE 1; MACROGOL; PROTOPORPHYRIN COBALT;

ARTERIOSCLEROSIS; BLOOD VESSEL TRANSPLANTATION; CARDIAC GRAFT REJECTION; CELL PROTECTION; CHRONIC GRAFT REJECTION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME MECHANISM; GENE OVEREXPRESSION; GENE TRANSFER; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HUMAN; INTESTINE TRANSPLANTATION; ISCHEMIA; KIDNEY INJURY; KIDNEY TRANSPLANTATION; LIVER INJURY; LIVER TRANSPLANTATION; LOW DRUG DOSE; NEPHROTOXICITY; NEUROTOXICITY; NONHUMAN; ORGAN TRANSPLANTATION; PANCREAS ISLET TRANSPLANTATION; PANCREAS TRANSPLANTATION; REPERFUSION INJURY; REVIEW; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; HEME OXYGENASE-1; HUMANS; ORGAN TRANSPLANTATION; REPERFUSION INJURY;

EID: 77956110010     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2010.15.031     Document Type: Review

References (40)

1. Shoskes DA, Halloran PF. Delayed graft function in renal transplantation: etiology, management and long-term significance. J Urol 1996; 155: 1831-1840.
2. Tsuchihashi S, Fondevila C, Kupiec-Weglinski JW. Heme oxygenase system in ischemia and reperfusion injury. Ann Transplant 2004; 9: 84-87.
3. Soares MP, Bach FH. Heme oxygenase-1: from biology to therapeutic potential. Trends Mol Med 2009; 15: 50-58.
4. Katori M, Busuttil RW, Kw JW. Heme oxygenase-1 system in organ transplantation. Transplantation 2002; 74: 905-912.
5. Fu WP, Zhao ZH, Fang LZ, Sun C, Liu L, Zhang JQ, et al. Heme oxygenase-1 polymorphism associated with severity of chronic obstructive pulmonary disease. Chin Med J 2007; 120: 12-16.
6. Li P, Elrayess MA, Gomma AH, Palmen J, Hawe E, Fox KM, et al. The microsatellite polymorphism of heme oxygenase-1is associated with baseline plasma IL-6 level but not with restenosis after coronary in-stenting. Chin Med J 2005; 118: 1525-1532.
7. Vachharajani TJ, Work J, Issekutz AC, Granger DN. Heme oxygenase modulates selectin expression in different regional vascular beds. Am J Physiol Heart Circ Physiol 2000; 278: H1613-H1617.
8. Neto JS, Nakao A, Kimizuka K, Romanosky AJ, Stolz DB, Uchiyama T, et al. Protection of transplant-induced renal ischaemic reperfusion injury with carbon monoxide. Am J Physiol Renal Physiol 2004; 287: 979-989.
9. Nakao A, Choi AM, Murase N. Protective effect of carbon monoxide in transplantation. J Cell Mol Med 2006; 10: 650-671.
10. Berberal PO, Katori M, Kaczmarek E, Anselmo D, Lassman C, Ke B, et al. Heavy chain ferritin acts as an anti-apoptotic gene that protects livers from ischaemic reperfusion injury. FASEB J 2003; 17: 1724-1726.
11. Jaeschke H, Hasegawa T. Role of neutrophils in acute inflammatory liver injury. Liver Int 2006; 268: 912-919.
12. Dorman RB, Bajt ML, Farhood A, Mayes J, Jaeschke H. Heme oxygenase-1 induction in hepatocytes and non-parenchymal cells protects against liver injury during endotoxemia. Comp Hepatol 2004; 3 Suppl 1: S42.
13. Yang ZF, Tsui TY, Ho DW. Heme oxygenase-1 potentiates the survival of small-for-size liver graft. Liver Transpl 2004; 10: 784-793.
14. Kobayashi T, Sato Y, Yamamoto S, Takeishi T, Hirano K, Watanabe T, et al. Augmentation of heme oxygenase-1 expression in the graft immediately after implantation in adult living-donor liver transplantation. Transplantation 2005; 79: 977-980.
15. Amersi F, Buelow R, Kato H, Ke B, Coito AJ, Shen XD, et al. Upregulation of heme oxygenase-1 protects genetically fat zuker rat liver from ischaemia/reperfusion injury. J Clin Invest 1999; 104: 1631-1639.
16. Coito AJ, Buelow R, Shen XD, Amersi F, Moore C, Volk HD, et al. Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat zucker rat livers from ischaemic reperfusion injury. Transplantation 2002; 74: 96-102.
17. Ke B, Buelow R, Shen XD, Melinek J, Amersi F, Gao F, et al. Heme oxygenase-1 gene transfer prevens CD95/Fas ligand-mediaed apoptosis and improves liver survival via carbon monoxide signaling pathway. Hum Gene Ther 2002; 13: 1189-1199.
18. Katori M, Buelow R, Ke B, Ma J, Coito AJ, Iyer S, et al. Heme oxygenase-1 overexpression protects rat hearts from cold ischaemia/reperfusion injury via an anti-apoptotic pathway. Transplantation 2002; 73: 287-292.
19. Araujo JA, Meng L, Tward AD, Hancock WW, Zhai Y, Lee A, el al. Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse. J Immunol 2003; 171: 1572-1580.
20. Orozco LD, Kapturczak MH, Barajas B, Wang X, Weinstein MM, Wong J, et al. Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis. Circ Res 2007; 100: 1703-1711.
21. Tsui TY, Wu X, Lau CK, Ho DW, Xu T, Siu YT, et al. Prevention of chronic deterioration of heart allograft by recombinant adeno-associated virus-mediated heme oxygenase-1 gene transfer. Circulation 2003; 107: 2623-2629.
22. Braudeau C, Bouchet D, Tesson L, Iyer S, Rémy S, Buelow R, et al. Induction of long term cardiac allograft survival by heme oxygenase-1 gene transfer. Gene Ther 2004; 11: 701-710.
23. Bouche D, Chauveau C, Roussel JC, Mathieu P, Braudeau C, Tesson L, et al. Inhibition of graft arteriosclerosis development in rat aortas following heme oxygenase-1 gene transfer. Transpl Immunol 2002; 9: 235-238.
24. Wagener FA, Eggert A, Boerman OC, Oyen WJ, Verhofstad A, Abraham NG, et al. Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase. Blood 2001; 98: 1802-1811.
25. Nath KA, Vercellotti GM, Grande JP, Miyoshi H, Paya CV, Manivel JC, et al. Heme protein-induced chronic renal inflammation: suppressive effect of induced heme oxygenase-1. Kidney Int 2001; 59: 106-117.
26. Salahudeen AA, Jenkins JK, Huang H, Ndebele K, Salahudeen AK. Overexpression of heme oxygenase protects renal tubular cells against cold storage injury: studies using hemin induction and heme oxygenase-1 gene transfer. Transplantation 2001; 72: 1498-1504.
27. Blydt-Hansen TD, Katori M, Lassman C, Ke B, Coito AJ, Iyer S, et al. Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/ reperfusion injury. J Am Soc Nephrol 2003; 14: 745-754.
28. Biarnes M, Montolio M, Nacher V, Raurell M, Soler J, Montanya E. Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes 2002; 51: 66-72.
29. Chen XB, Li YX, Jiao Y, Dong WP, Li G, Chen J, et al. Influence of heme oxygenase-1 gene transfer on the viability and function of rat islets in in vitro culture. World J Gastroenterol 2007; 13: 1053-1059.
30. Li YX, Li G, Dong WP, Lu DR, Tan JM. Protection of human islets from induction of apoptosis and improved islet function with heme oxygenase-1 gene transduction. Chin Med J 2006; 119: 1639-1645.
31. Li YX, Li G, Dong WP, Chen J, Wang YF, Chen XB, et al. Transductions of heme oxygenase-1 gene to human islet cells via adenovirus vector enhances anti-apoptosis function and insulin release. Chin Med J 2006; 86: 915-918.
32. Nakao A, Kimizuka K, Stolz DB, Neto JS, Kaizu T, Choi AM, et al. Carbon monoxide inhalation protects rat intestinal grafts from ischaemia/reperfusion injury. Am J Pathol 2003; 163: 1587-1598.
33. Nakao A, Otterbein LE, Overhaus M, Sarady JK, Tsung A, Kimizuka K, et al. Biliverdin protects the functional integrity of a transplanted syngeneic small bowel. Gastroenterology 2004; 127: 595-606.
34. Yasuhara M. L-glutamine-induced heme oxygenase-1 protects small intestine from warm ischaemia and reperfusion injury in the rat. Hokkaido Igaku Zasshi (Jpn) 2001; 76: 21-34.
35. Lee DY, Lee S, Nam JH, Byun Y. Minimization of immunosuppressive therapy after islet transplantation: combined action of heme oxygenase-1 and PEGylation to islet. Am J Transplant 2006; 6: 1820-1828.
36. Rezzani R, Rodella L, Bianchi R, Goodman AI, Lianos EA. Protective effects of heme-oxygenase expression in cyclosporine-induced injury. Curr Neurovasc Res 2005; 2: 157-161.
37. Lu F, Zander DS, Visner GA. Increased expression of heme oxygenase-1 in human lung transplantation. J Heart Lung Transplant 2002; 21: 1120-1126.
38. Pang QF, Zhou QM, Zeng S, Dou LD, Ji Y, Zeng YM. Protective effect of heme oxygenase-1 on lung injury induced by erythrocyte instillation in rats. Chin Med J 2008; 121: 1688-1692.
39. Chen YS, Zhu XX, Zhao XY, Xing HY, Li YG. Hemin, a hemeoxygenase-1 inducer, improves aortic endothelial dysfunction in insulin resistant rats. Chin Med J 2008; 121: 241-247.
40. Giriş M, Erbil Y, Oztezcan S, Olgaç V, Barbaros U, Deveci U, et al. The effect of heme oxygenase-1 induction by glutamine on radiation-induced intestinal damage: the effect of heme oxygenase-1 on radiation enteritis. Am J Surg 2006; 191: 503-509.