A review of keratin-based biomaterials for biomedical applications

Materials

Volumn 3, Issue 2, 2010, Pages 999-1014

  Rouse, Jillian G ^a   Van Dyke, Mark E ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Human hair protein; Keratin; Natural biomaterial; Protein film; Scaffold

Indexed keywords

BIOMEDICAL APPLICATIONS; CELLULAR RECOGNITION; HUMAN HAIR PROTEINS; MEDICAL DEVICES; NATURAL BIOMATERIALS; PROTEIN FILMS; SELF ASSEMBLED STRUCTURES; WOUND HEALING;

BIOACTIVITY; BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; BIOMEDICAL EQUIPMENT; DRUG DELIVERY; KERATIN; MEDICAL APPLICATIONS; SCAFFOLDS;

SCAFFOLDS (BIOLOGY);

EID: 77956092359     PISSN: None     EISSN: 19961944     Source Type: Journal    
DOI: 10.3390/ma3020999     Document Type: Review

References (75)

1. Moll, R.; Franke, W.W.; Schiller, D.L.; Geiger, B.; Krepler, R. The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982, 31, 11-24.
2. Fraser, R.D.; MacRae, T.P.; Parry, D.A.; Suzuki, E. Intermediate filaments in alpha-keratins. Proc. Natl. Acad. Sci. USA 1986, 83, 1179-1183.
3. Coulombe, P.A.; Bousquet, O.; Ma, L.; Yamada, S.; Wirtz, D. The 'ins' and 'outs' of intermediate filament organization. Tr. Cell Biol. 2000, 10, 420-428.
4. Schweizer, J.; Bowden, P.E.; Coulombe, P.A.; Langbein, L.; Lane, E.B.; Magin, T.M.; Maltais, L.; Omary, M.B.; Parry, D.A.; Rogers, M.A.; Wright, M.W. New consensus nomenclature for mammalian keratins. J. Cell Biol. 2006, 174, 169-174.
5. Moll, R.; Divo, M.; Langbein, L. The human keratins: Biology and pathology. Histochem. Cell Biol. 2008, 129, 705-733.
6. Yu, J.; Yu, D.; Checkla, D.M.; Freedberg, I.M.; Bertolino, A.P. Human Hair Keratins. J. Invest. Dermatol. 1993, 101, 56S-59S.
7. Crewther, W.G.; Fraser, R.D.B.; Lennox, F.G.; Lindley, H. The Chemistry of Keratins. In Advances in Protein Chemistry; Anfinsen, C.B., Anson, M.L., Edsall, J.T., Richards, F.M., Eds.; Academic Press: New York, USA, 1965; Volume 20, pp. 191-347.
8. Rogers, M.A.; Langbein, L.; Praetzel-Wunder, S.; Winter, H.; Schweizer, J. Human hair keratinassociated proteins (KAPs). Int. Rev. Cytol. 2006, 251, 209-263.
9. Stenn, K.S.; Paus, R. What controls hair follicle cycling? Exp. Dermatol. 1999, 8, 229-233.
10. Alonso, L.; Fuchs, E. The hair cycle. J. Cell Sci. 2006, 119, 391-393.
11. Langbein, L.; Rogers, M.A.; Winter, H.; Praetzel, S.; Beckhaus, U.; Rackwitz, H.R.; Schweizer, J. The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle. J. Biol. Chem. 1999, 274, 19874-19884.
12. Langbein, L.; Rogers, M.A.; Winter, H.; Praetzel, S.; Schweizer, J. The catalog of human hair keratins. II. Expression of the six type II members in the hair follicle and the combined catalog of human type I and II keratins. J. Biol. Chem. 2001, 276, 35123-35132.
13. Langbein, L.; Schweizer, J. Keratins of the human hair follicle. Int. Rev. Cytol. 2005, 243, 1-78.
14. Schweizer, J.; Langbein, L.; Rogers, M.A.; Winter, H. Hair follicle-specific keratins and their diseases. Exp. Cell Res. 2007, 313, 2010-2020.
15. Zhen, L.S. Ben Cao Gang Mu; The Time Literature & Art Press: Changchun, Jilin, China, 2005.
16. Hofmeier, J. Horn-lime plastic masses from keratin substances. German Pat. DE184915, 18 December 1905.
17. Breinl, F.; Baudisch, O. The oxidative breaking up of keratin through treatment with hydrogen peroxide. Z Physiol. Chem. 1907, 52, 158-169.
18. Neuberg, C. Process of producing digestable substances from keratin. US Pat. 926,999, 6 July 1909.
19. Lissizin, T. Behavior of keratin sulfur and cystin sulfur in the oxidation of these proteins by potassium permanganate I. Biochem. Bull. 1915, 4, 18-23.
20. Zdenko, S. Solubility and digestibility of the degradation products of albumoids I. Z Physiol. Chem. 1924, 136, 160-172.
21. Lissizin, T. The oxidation products of keratin by oxidation with permanganate II. Z Physiol. Chem. 1928, 173, 309-311.
22. Goddard, D.R.; Michaelis, L. Derivatives of Keratin. J. Biol. Chem. 1935, 112, 361-371.
23. Beyer, C. The keratin or horny substance of the hair. German Pat. DE22643, 14 October 1907.
24. Goldsmith, B.B. Thermoplastic composition containing keratin. US Pat. 922,692, 25 May 1909.
25. Dale, H.N. Keratin and other coatings for pills. Pharm. J. 1932, 129, 494-495.
26. Rivett, D.E.; Ward, S.W.; Belkin, L.M.; Ramshaw, J.A.M.; Wilshire, J.F.K. Keratin and Wool Research. In The Lennox Legacy; CSIRO Publishing: Collingwood, VIC, Australia, 1996.
27. van den Bergh, J.; Milo, G.J.; van Dijk, H.E.P. Keratin-resin threads, films, etc. Netherlands Pat. NL51000577, 15 December 1941.
28. Orwin, D.F.G; Baumann, H.; Asquith, R.S.; Parry, D.A.D. In Fibrous Proteins: Scientific, Industrial and Medical Aspects; Parry, D.A.D., Creamer, L.K., Eds.; Academic Press: New York, NY, USA 1979; pp. 271-427.
29. Earland, C.; Knight, C.S. Structure of keratin II: Amino acid content of fractions isolated from oxidized wool. Biochem. Biophys. Acta 1956, 22, 405-411.
30. Kikkawa, M.; Chonan, Y.; Toyoda, H. Solubilization of keratin 6: Solubilization of feather keratin by oxidation with performic acid. Hikaku Kagaku 1974, 20, 151-162.
31. Buchanan, J.H. A cystine-rich protein fraction from oxidized alpha-keratin Biochem. J. 1977, 167, 489-491.
32. Matsunga, A.; Chonan, Y.; Toyoda, H. Studies on the chemical properties of human hair keratin, Part 1: Fractionation and amino acid composition of human hair solubilized by performic acid oxidation. Hikaku Kagaku 1981, 27, 21-29.
33. Anker, C.A. Method of preparing keratin-containing films and coatings. US Pat. 3,642,498, 15 February 1972.
34. Kawano, Y.; Okamoto, S. Film and gels of keratin. Kagaku Seibutsu 1975, 13, 291-292.
35. Okamoto, S. Formation of films from some proteins. Nippon Shokuhin Kogyo Gakkaishi 1977, 24, 40-50.
36. Noishiki, Y.; Ito, H.; Miyamoto, T.; Inagaki, H. Application of Denatured Wool Keratin Derivatives to an Antithrombogenic Biomaterial-Vascular Graft Coated with a Heparinized Keratin Derivative. Kobunshi Ronbunshu 1982, 39, 221-227.
37. Ito, H.; Miyamoto, T.; Inagaki, H.; Noishiki, Y. Biocompatibility of Denatured Keratins from Wool. Kobunshi Ronbunshu 1982, 39, 249-256.
38. Jarman, T.; Light, J. Prospects for novel biomaterials development. In World Biotech Report; Pinner: Middlesex, UK, 1985; Volume 1, pp. 505-512.
39. Various Authors Biomaterial forefront: Keratin which can be extracted by simple chemical technique. Kogyo Zairyo 1993, 41, 106-109.
40. van de Locht, M. Reconstitution of microfibrils from wool and filaments from epidermis proteins. Melliand Textilberichte 1987, 10, 780-786.
41. Steinert, P.M.; Gullino, M.I. Bovine epidermal keratin filament assembly in vitor. Biochem. Biophys. Res. Commun. 1976, 70, 221-227.
42. Thomas, H.; Conrads, A.; Phan, P.H.; van de Locht, M.; Zahn, H. In vitor reconstitution of wool intermediate filaments. Int. J. Biol. Macromol. 1986, 8, 258-264.
43. Ikkai, F.; Naito, S. Dynamic light scattering and circular dichroism studies on heat-induced gelation of hard-keratin protein aqueous solutions. Biomacromolecules 2002, 3, 482-487.
44. Tachibana, A.; Furuta, Y.; Takeshima, H.; Tanabe, T.; Yamauchi, K. Fabrication of wool keratin sponge scaffolds for long-term cell cultivation. J. Biotechnol. 2002, 93, 165-170.
45. Verma, V.; Verma, P.; Ray, P.; Ray, A.R. Preparation of scaffolds from human hair proteins for tissue-engineering applications. Biomed. Mater. 2008, 3, 25007.
46. Magin, T.M.; Vijayaraj, P.; Leube, R.E. Structural and regulatory functions of keratins. Exp. Cell Res. 2007, 313, 2021-2032.
47. Izawa, I.; Inagaki, M. Regulatory mechanisms and functions of intermediate filaments: A study using site- and phosphorylation state-specific antibodies. Cancer Sci. 2006, 97, 167-174.
48. Yamauchi, K.; Yamauchi, A.; Kusunoki, T.; Kohda, A.; Konishi, Y. Preparation of stable aqueous solution of keratins, and physiochemical and biodegradational properties of films. J. Biomed. Mater. Res. 1996, 31, 439-444.
49. Yamauchi, K.; Maniwa, M.; Mori, T. Cultivation of fibroblast cells on keratin-coated substrata. J. Biomat. Sci.-Polym. E. 1998, 9, 259-270.
50. Fujii, T.; Ogiwara, D.; Arimoto, M. Convenient procedures for human hair protein films and properties of alkaline phosphatase incorporated in the film. Biol. Pharm. Bull. 2004, 27, 89-93.
51. Tanabe, T.; Okitsu, N.; Tachibana, A.; Yamauchi, K. Preparation and characterization of keratinchitosan composite film. Biomaterials 2002, 23, 817-825.
52. Yamauchi, K.; Hojo, H.; Yamamoto, Y.; Tanabe, T. Enhanced cell adhesion on RGDS-carrying keratin film. Mat. Sci. Eng. C-Bio. S. 2003, 23, 467-472.
53. Lee, K.Y.; Ha, W.S. DSC studies on bound water in silk fibroin/S-carboxymethyl kerateine blend films. Polymer 1999, 40, 4131-4134.
54. Lee, K.Y.; Kong, S.J.; Park, W.H.; Ha, W.S.; Kwon, I.C. Effect of surface properties on the antithrombogenicity of silk fibroin/S-carboxymethyl kerateine blend films. J. Biomater. Sci. Polym. Ed. 1998, 9, 905-914.
55. Lee, K.Y. Characterization of Silk/Fibroin/S-carboxymethyl Kerateine Surfaces: Evaluation of Biocompatibility by Contact Angle Measurements. Fibers Polym. 2001, 2, 71-74.
56. Vasconcelos, A.; Freddi, G.; Cavaco-Paulo, A. Biodegradable materials based on silk fibroin and keratin. Biomacromolecules 2008, 9, 1299-1305.
57. Tonin, C.; Aluigi, A.; Vineis, C.; Varesano, A.; Montarsolo, A.; Ferrero, F. Thermal and structural characterization of poly(ethylene-oxide)/keratin blend films. J. Therm. Anal. Calorim. 2007, 89, 601-608.
58. Zoccola, M.; Montarsolo, A.; Aluigi, A.; Varesano, A.; Vineis, C.; Tonin, C. Electrospinning of polyamide 6/modified-keratin blends. E-Polym. 2007, no. 105.
59. Fujii, T.; Ide, Y. Preparation of translucent and flexible human hair protein films and their properties. Biol. Pharm. Bull. 2004, 27, 1433-1436.
60. Katoh, K.; Shibayama, M.; Tanabe, T.; Yamauchi, K. Preparation and physicochemical properties of compression-molded keratin films. Biomaterials 2004, 25, 2265-2272.
61. Reichl, S. Films based on human hair keratin as substrates for cell culture and tissue engineering. Biomaterials 2009, 30, 6854-6866.
62. Kurimoto, A.; Tanabe, T.; Tachibana, A.; Yamauchi, K. Keratin sponge: Immobilization of lysozyme. J. Biosci. Bioeng. 2003, 96, 307-309.
63. Tachibana, A.; Kaneko, S.; Tanabe, T.; Yamauchi, K. Rapid fabrication of keratin-hydroxyapatite hybrid sponges toward osteoblast cultivation and differentiation. Biomaterials 2005, 26, 297-302.
64. Tachibana, A.; Nishikawa, Y.; Nishino, M.; Kaneko, S.; Tanabe, T.; Yamauchi, K. Modified keratin sponge: Binding of bone morphogenetic protein-2 and osteoblast differentiation. J. Biosci. Bioeng. 2006, 102, 425-429.
65. Katoh, K.; Tanabe, T.; Yamauchi, K. Novel approach to fabricate keratin sponge scaffolds with controlled pore size and porosity. Biomaterials 2004, 25, 4255-4262.
66. Peplow, P.V.; Dias, G.J. A study of the relationship between mass and physical strength of keratin bars in vivo. J. Mater. Sci. Mater. Med. 2004, 15, 1217-1220.
67. Aluigi, A.; Varesano, A.; Montarsolo, A.; Vineis, C.; Ferrero, F.; Mazzuchetti, G.; Tonin, C. Electrospinning of keratin/poly(ethylene oxide) blend nanofibers. J. Appl. Polym. Sci. 2007, 104, 863-870.
68. Aluigi, A.; Vineis, C.; Varesano, A.; Mazzuchetti, G.; Ferrero, F.; Tonin, C. Structure and properties of keratin/PEO blend nanofibres. Eur. Polym. J. 2008, 44, 2465-2475.
69. Varesano, A.; Aluigi, A.; Vineis, C.; Tonin, C. Study on the shear viscosity behavior of keratin/PEO blends for nanofibre electrospinning. J. Polym. Sci. Poly. Phys. 2008, 46, 1193-1201.
70. Zoccola, M.; Aluigi, A.; Vineis, C.; Tonin, C.; Ferrero, F.; Piacentino, M.G. Study on cast membranes and electrospun nanofibers made from keratin/fibroin blends. Biomacromolecules 2008, 9, 2819-2825.
71. Katoh, K.; Shibayama, M.; Tanabe, T.; Yamauchi, K. Preparation and properties of keratinpoly(vinyl alcohol) blend fiber. J. Appl. Polym. Sci. 2004, 91, 756-762.
72. Wrześniewska-Tosik, K.; Wawro, D.; Ratajska, M.; Ste{ogonek}plewski, W. Novel composites with feather keratin. Fibres Text. East. Eur. 2007, 15, 157-162.
73. Sierpinski, P.; Garrett, J.; Ma, J.; Apel, P.; Klorig, D.; Smith, T.; Koman, L.A.; Atala, A.; Van Dyke, M. The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves. Biomaterials 2008, 29, 118-128.
74. Apel, P.J.; Garrett, J.P.; Sierpinski, P.; Ma, J.; Atala, A.; Smith, T.L.; Koman, L.A.; Van Dyke, M.E. Peripheral nerve regeneration using a keratin-based scaffold: Long-term functional and histological outcomes in a mouse model. J. Hand Surg. Am. 2008, 33, 1541-1547.
75. Aboushwareb, T.; Eberli, D.; Ward, C.; Broda, C.; Holcomb, J.; Atala, A.; Van Dyke, M. A Keratin biomaterial gel hemostat derived from human hair: Evaluation in a rabbit model of lethal liver injury. J. Biomed. Mater. Res. B 2009, 90, 45-54.