Microgravity-induced alterations in signal transduction in cells of the immune system

Acta Astronautica

Volumn 67, Issue 9-10, 2010, Pages 1116-1125

  Paulsen, Katrin ^a   Thiel, Cora ^b   Timm, Johanna ^a   Schmidt, Peter M ^c   Huber, Kathrin ^a   Tauber, Svantje ^a   Hemmersbach, Ruth ^d   Seibt, Dieter ^d   Kroll, Hartmut ^e   Grote, Karl Heinrich ^f   Zipp, Frauke ^g   Schneider Stock, Regine ^h   Cogoli, Augusto ⁱ   Hilliger, Andre ^j,k   Engelmann, Frank ^j,k   Ullrich, Oliver ^a,f  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c CSIRO   (Australia)

^d GERMAN AEROSPACE CENTER DLR   (Germany)

^e Institute for Transfusion Medicine Dessau   (Germany)

^f OTTO VON GUERICKE UNIVERSITY   (Germany)

^g UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^h Experimental Tumorpathology   (Germany)

ⁱ Zero g LifeTec GmbH   (Switzerland)

^j UNIVERSITY OF APPLIED SCIENCES JENA   (Germany)

^k KEK GmbH   (Germany)

more..

Author keywords

Adaptive immunity; Gravisensitivity; Innate immunity; Signal transduction; Spaceflight

Indexed keywords

ADAPTIVE IMMUNITY; CELL LINES; CELLULAR RESPONSE; CLINOSTAT; GRAVISENSITIVITY; IDEAL MODEL; IMMUNE CELLS; IMMUNE SYSTEMS; IN-CELL; INNATE IMMUNITY; MAMMALIAN CELL FUNCTION; MAP KINASE; MOLECULAR ASPECTS; MOLECULAR MECHANISM; NUCLEAR TRANSLOCATIONS; P53 PROTEIN; PARABOLIC FLIGHT; SENSITIVE MECHANISM; SIGNAL PATHWAYS; SIMULATED WEIGHTLESSNESS; SPACE MISSIONS; STIMULATED CELLS; T CELLS; T LYMPHOCYTES; THERAPEUTIC TARGETS; U937 CELL;

AMINO ACIDS; BACTERIOPHAGES; CELL CULTURE; IMMUNOLOGY; MAMMALS; MANNED SPACE FLIGHT; MICROGRAVITY; MICROGRAVITY PROCESSING; PHOSPHATASES; PHOSPHORYLATION;

SIGNAL TRANSDUCTION;

EID: 77956055620     PISSN: 00945765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actaastro.2010.06.053     Document Type: Article

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