Hyperhomocysteinemia's effect on antioxidant capacity in rats

Central European Journal of Medicine

Volumn 5, Issue 5, 2010, Pages 620-626

  Filip, Christian ^a   Albu, Elena ^a   Zamosteanu, Nina ^a   Irina, M Jaba ^a   Silion, Mihaela ^b   Jerca, Luminita ^a   Gheorghita, Nastasia ^a   Costel, Mungiu O ^a  

^a GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Romania)

Author keywords

GPx; Hyperhomocysteine; Methionine; SOD; TAS

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; GLUTATHIONE PEROXIDASE; HOMOCYSTEINE; METHIONINE; SUPEROXIDE DISMUTASE;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT CAPACITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE; EXTRACELLULAR SPACE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERHOMOCYSTEINEMIA; INTRACELLULAR SPACE; MALE; METABOLIC PARAMETERS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 77956047472     PISSN: 18951058     EISSN: 16443640     Source Type: Journal    
DOI: 10.2478/s11536-010-0032-7     Document Type: Article

References (29)

1. K. McCully R. Wilson 1975 Homocysteine theory of arteriosclerosis Atherosclerosis 22 215 227 10.1016/0021-9150(75)90004-0 1:CAS:528:DyaE28XhtVyh 1191372
2. G. Starkekbaum J. Harlan 1986 Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine J Clin Invest 77 1370 1376 10.1172/JCI112442
3. J. Stamler J. Loscallzo 1992 Endothelium-derived relaxing factor modulates the atherothrombogenic effects of homocysteine J Cardiol Pharmacol 20 S202 S204 1:CAS:528:DyaK3sXhsVCrsL0%3D
4. J. Stamler J. Osborne O. Jaraki 1993 Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen J Clin Invest 91 308 318 10.1172/JCI116187 1:CAS:528:DyaK3sXhsVCrsbw%3D 8380812
5. G.J. Upchurch G. Welch J. Loscalzo 1996 Homocysteine EDRF and endothelial function J Nutr 126 1290S 1294S 1:CAS:528:DyaK28XhvFant74%3D 8642473
6. G.J. Upchurch G. Welch A. Fabian 1997 Homocyst(e) ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase J Biol Chem 272 17012 17017 10.1074/jbc.272.27.17012 1:CAS:528:DyaK2sXksVeltbs%3D 9202015
7. P.M. Kanani C.A. Sinkey R.L. Browning 1999 Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans Circulation 100 1161 1168 1:CAS:528:DyaK1MXmsVartrk%3D 10484535
8. G. Topol A. Brunet E. Millanvoye 2004 Homocysteine induces oxidative stress by uncoupling of NO synthase through reduction of tetrahydrobiopterin Free Radic Biol Med 36 1532 1541 10.1016/j.freeradbiomed.2004.03.019
9. N.M. Al-Daghri O.S. Al-Attas 2008 Homocysteinemia, hypertension, and family history of diabetes in a smoking male population in Saudi Arabia Central European Journal of Medicine 3 2 167 172 10.2478/s11536-008-0019-9 1:CAS:528:DC%2BD1cXpsVGhuro%3D
10. F. Wotherspoon D.W. Laight K.M. Shaw M.H. Cummings 2003 Review: Homocysteine, endothelial dysfunction and oxidative stress in type 1 diabetes mellitus The British Journal of Diabetes & Vascular Disease 3 5 334 340 10.1177/14746514030030050401 1:CAS:528:DC%2BD3sXpt1ehtLg%3D
11. L. Wu J. Wu S. Hunt 1994 Plasma homocyst(e) ine as a risk factor for early familial coronary artery disease Clin Chem 40 552 561 1:STN:280: DyaK2c7pvFyitg%3D%3D 8149609
12. K. Dalery S. Lussier-Cacan J. Selhub 1995 Homocysteine and coronary artery disease in French Canadian subjects: relation with vitamins B12, B6, pyridoxal phosphate, and folate Am J Cardiol 75 1107 1111 10.1016/S0002-9149(99) 80739-5 1:STN:280:DyaK2M3ot1Oitw%3D%3D 7762494
13. P. Verhoef M. Stampfer J. Buring 1996 Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12 and folate Am J Epidemiol 14 845 859
14. P. Verhoef F. Kok D. Kruyssen 1997 Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis Arterioscler Thromb Vasc Biol 17 989 995 1:STN:280:DyaK2szgtFGltg%3D%3D 9157965
15. K. Robinson K. Arheart H. Refsum 1998 Low circulating folate and vitamin B6 concentrations. Risk factors for stroke, peripheral vascular disease, and coronary artery disease Circulation 97 437 443 1:STN:280:DyaK1c7ktVKkuw%3D%3D 9490237
16. K. McCully B. Ragsdale 1970 Production of arteriosclerosis by homocysteinemia Am J Pathol 61 1 8 1:CAS:528:DyaE3cXkvFKls78%3D 5488869
17. L. Harker J. Harian R. Ross 1983 Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons Circ Res 53 731 739 1:CAS:528:DyaL2cXmtFGrtw%3D%3D 6640860
18. N. Weiss 2005 Mechanisms of increased vascular oxidant stress in hyperhomocysteinemia and its impact on endothelial function Curr Drug Metab 6 27 36 10.2174/1389200052997357 1:CAS:528:DC%2BD2MXhsVCqtLw%3D 15720205
19. F.Q. Schafer G.R. Buettner 2001 Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple Free Radic. Biol. Med. 30 11 1191 212 10.1016/S0891-5849(01)00480-4 1:CAS:528:DC%2BD3MXjsFegt78%3D 11368918
20. S.V. Lennon S.J. Martin T.G. Cotter 1991 Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli Cell Prolif 24 2 203 14 10.1111/j.1365-2184.1991.tb01150.x 1:STN:280:DyaK3M7otlSktg%3D%3D 2009322
21. N. Boyce 1997 Oxidative Stress Testing: A New Addition to Lab Menus? Clin. Lab News 23 1 2
22. E. Bald E. Kaniowska G. Chwatko R. Glowacki 2000 Liquid chromatographic assessment of total and protein-bound homocysteine in human plasma Talanta 50 1233 1243 10.1016/S0039-9140(99)00235-0 1:CAS:528:DC%2BD3cXhvVCh 18967819
23. G. Chwatko G. Bald 2002 Determination of different species of homocysteine in human plasma by highperformance liquid chromatography with ultraviolet detection Journal of Chromatography A 949 1-2 141 151 10.1016/S0021-9673(01)01343-7 1:CAS:528:DC%2BD38XhsFCmtrg%3D 11999730
24. N. Khandanpour Y.K. Loke F.J. Meyer B. Jennings M.P. Armon 2009 Homocysteine and peripheral arterial disease: systematic review and meta-analysis Eur J Vasc Endovasc Surg. 38 3 316 22 10.1016/j.ejvs.2009.05.007 1:STN:280:DC%2BD1Mrlt1ylug%3D%3D 19560951
25. F. Hirche A. Schröder B. Knoth G.I. Stangl K. Eder 2006 Methionine-induced elevation of plasma homocysteine concentration is associated with an increase of plasma cholesterol in adult rats Ann Nutr Metab 50 139 146 10.1159/000090635 1:CAS:528:DC%2BD28XhvV2jsr8%3D 16391469
26. V. Herbert R. Zalusky 1962 lnterrelation of vitamin B12 and folic metabolism: folic acid clearance studies J Clin Invest 41 1263 1276 10.1172/JCI104589 1:CAS:528:DyaF38XksFWlt7c%3D 13906634
27. J. Selhub 1999 Homocysteine metabolism Annu Rev Nutr 19 217 246 10.1146/annurev.nutr.19.1.217 1:CAS:528:DyaK1MXlt1ejsLw%3D 10448523
28. P.M. Ueland H. Refsum R. Male J.R. Lillehaug 1986 Disposition of endogenous homocysteine by mouse fibroblast C3H/10T1/2 CI 8 and the chemically transformed C3H/10T1/2 MCA CI 16 cells following methotrexate exposure J Natl Cancer Inst 77 283 289 1:CAS:528:DyaL28XkvFSqs7o%3D 3459921
29. B. Christensen H. Refsum O. Vintermyr P.M. Ueland 1999 Homocysteine export from cells cultured in the presence of physiological or superfluous levels of methionine: methionine loading of nontransformed, transformed, proliferating, and quiescent cells in culture J Cell Biol 146 52 62