Antioxidant/prooxidant effects of bioactive polyphenolics

Electronic Journal of Environmental, Agricultural and Food Chemistry

Volumn 7, Issue 8, 2008, Pages 3348-3352

  Tourino S ^a   Lizarraga D ^b   Carreras, A ^a   Matito, C ^b   Ugartondo, V ^b   Mitjans, M ^b   Centelles, J J ^b   Vinardell, M P ^b   Julia L ^a   Cascante, M ^b   Torres, J L ^a  

^a DEPARTMENT OF ENVIRONMENTAL CHEMISTRY   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Antioxidants; Catechins; Cell proliferation; Cytotoxicity; Hemolysis; Polyphenols; Proanthocyanidins; Tannins

Indexed keywords

HAMAMELIS; HAMAMELIS VIRGINIANA; VITACEAE;

EID: 77956034700     PISSN: None     EISSN: 15794377     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Alanko, J., Riutta, A., Holm, P., Mucha, I., Vapaatalo, H. and Metsa-Ketela, T. 1999. Modulation of arachidonic acid metabolism by phenols: relation to their structure and antioxidant/prooxidant properties. Free Radical Biol. Med. 26: 1-201.
2. Boots, A. W., Li, H., Schins, R. P. F., Duffin, R., Heemskerk, J. W. M., Bast, A. and Haenen, G. 2007. The quercetin paradox. Toxicol. Appl. Pharmacol. 222: 1-96.
3. Kondo, K., Kurihara, M., Miyata, N., Suzuki, T. and Toyoda, M. 1999. Scavenging mechanisms of (-)-epigallocatechin gallate and (-)-epicatechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action. Free Radical Biol. Med. 27: 1-863.
4. Lizárraga, D., Lozano, C., Briede, J. J., van Delft, J. H., Touriño, S., Centelles, J. J., Torres, J. L. and Cascante, M. 2007. The importance of polymerization and galloylation for the antiproliferative properties of procyanidin-rich natural extracts. FEBS J. 274: 1-4811.
5. Rice-Evans, C. A., Miller, N. J. and Paganga, G. 1996. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biol. Med. 20: 1-956.
6. Tan, X. H., Hu, D. R., Li, S. R., Han, Y., Zhang, Y. L. and Zhou, D. Y. 2000. Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells. Cancer Lett. 158: 1-6.
7. Torres, J. L., Varela, B., García, M. T., Carilla, J., Matito, C., Centelles, J. J., Cascante, C., Sort, X. and Bobet, R. 2002. Valorization of grape (Vitis vinifera) byproducts. Antioxidant and biological properties of polyphenolic fractions differing in procyanidin composition and flavonol content. J. Agric. Food Chem. 50: 1-7555.
8. Touriño, S., Lizárraga, D., Carreras, A., Lorenzo, S., Ugartondo, V., Mitjans, M., Vinardell, M. P., Juliá, L., Cascante, M. and Torres, J. L. 2008. Highly Galloylated Tannin Fractions from Witch Hazel (Hamamelis virginiana) Bark: Electron Transfer Capacity, In Vitro Antioxidant Activity and Effects on Skin Related Cells. Chem. Res. Toxicol.: in press, doi: 10.1021/tx700362u.
9. Touriño, S., Selga, A., Jiménez, A., Juliá, L., Lozano, C., Lizárraga, D., Cascante, M. and Torres, J. L. 2005. Procyanidin fractions from pine (Pinus pinaster) bark: Radical scavenging power in solution, antioxidant activity in emulsion and antiproliferative effect in melanoma cells. J. Agric. Food Chem. 53: 1-4735.
10. Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T. D., Mazur, M. and Telser, J. 2007. Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 39: 1-84.