Adrenomedullin relaxes rat uterine artery: Mechanisms and influence of pregnancy and estradiol

Endocrinology

Volumn 151, Issue 9, 2010, Pages 4485-4493

  Ross, Gracious R ^a,b   Yallampalli, Uma ^b   Gangula, Pandu R R ^b   Reed, Luckey ^b   Sathishkumar, K ^b   Gao, Haijun ^b   Chauhan, Madhu ^b   Yallampalli, Chandra ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOMEDULLIN; CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE-RELATED PEPTIDE (8-37); ESTRADIOL; GLIBENCLAMIDE; MEMBRANE PROTEIN; PEPTIDE FRAGMENT; POTASSIUM CHANNEL BLOCKING AGENT; PROGESTERONE; RECEPTOR ACTIVITY MODIFYING PROTEIN; SIGNAL PEPTIDE; VASODILATOR AGENT;

ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; FEMALE; GENE EXPRESSION; GENETICS; IN VITRO STUDY; METABOLISM; OVARIECTOMY; PHYSIOLOGY; PREGNANCY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; UTERINE ARTERY; VASCULAR ENDOTHELIUM; VASODILATATION;

ADRENOMEDULLIN; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ESTRADIOL; FEMALE; GENE EXPRESSION; GLYBURIDE; IN VITRO TECHNIQUES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; OVARIECTOMY; PEPTIDE FRAGMENTS; POTASSIUM CHANNEL BLOCKERS; PREGNANCY; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR ACTIVITY-MODIFYING PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UTERINE ARTERY; VASODILATION; VASODILATOR AGENTS;

EID: 77956029482     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-0096     Document Type: Article

References (44)

1. Magness RR 1998 Maternal cardiovascular and other physiologic responses to the endocrinology of pregnancy. In: Fuller B, ed. Endocrinology of pregnancy. Totowa, NJ: Humana Press, Inc.; 507-539
2. Rosenfeld CR 1977 Distribution of cardiac output in ovine pregnancy. Am J Physiol 232:H231-H235
3. Greenwald P 1963 Chronic fetal distrus and placental insufficiency. Neonate 5:215-219
4. Leiberman JR, Wiznitzer A, Glezerman M, Feldman B, Levy J, Sharoni Y 1993 Estrogen and progesterone receptors in the uterine artery of rats during and after pregnancy. Eur J Obstet Gynecol Reprod Biol 51:35-40
5. Peeters LL, Grutters G, Martin Jr CB 1980 Distribution of cardiac output in the unstressed pregnant guinea pig. Am J Obstet Gynecol 138:1177-1184
6. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, Eto T 1993 Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 192:553-560 (Pubitemid 23227359)
7. Di Iorio R, Marinoni E, Letizia C, Alò P, Villaccio B, Cosmi EV 1998 Adrenomedullin, a new vasoactive peptide, is increased in preeclampsia. Hypertension 32:758-763
8. Jerat S, Kaufman S 1998 Effect of pregnancy and steroid hormones on plasma adrenomedullin levels in the rat. Can J Physiol Pharmacol 76:463-466 (Pubitemid 28475403)
9. Penchalaneni J, Wimalawansa SJ, Yallampalli C 2004 Adrenomedullin antagonist treatment during early gestation in rats causes fetoplacental growth restriction through apoptosis. Biol Reprod 71:1475-1483
10. van der Heijden O, Essers YP, van Eyndhoven HW, Spaanderman ME, Aardenburg R, van Eys GJ, Peeters LL 2005 Vascular expression of adrenomedullin is increased in Wistar rats during early pregnancy. Eur J Obstet Gynecol Reprod Biol 123:35-40
11. Weiner CP, Lizasoain I, Baylis SA, Knowles RG, Charles IG, Moncada S 1994 Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc Natl Acad Sci USA 91:5212-5216 (Pubitemid 24177823)
12. Buhimschi I, Yallampalli C, Chwalisz K, Garfield RE 1995 Preeclampsia-like conditions produced by nitric oxide inhibition: effects of L-arginine, D-arginine and steroid hormones. Hum Reprod 10:2723-2730
13. Grbović L, Jovanović A 1996 Effect of the vascular endothelium on contractions induced by prostaglandin F2 α in isolated pregnant guinea pig uterine artery. Hum Reprod 11:2041-2047
14. Grbović L, Jovanović A 1997 Indomethacin depresses prostaglandin F2 α-induced contraction in guinea-pig uterine artery with both intact and denuded endoth. Prostaglandins 53:371-379
15. Nelson SH, Steinsland OS, Suresh MS, Lee NM 1998 Pregnancy augments nitric oxide-dependent dilator response to acetylcholine in the human uterine artery. Hum Reprod 13:1361-1367
16. Matsumoto T, Kanamaru K, Sugiyama Y, Murata Y 1992 Endothelium-derived relaxation of the pregnant and nonpregnant canine uterine artery. J Reprod Med 37:529-533
17. Jovanović A, Grbović L, Jovanović S 1995 Effect of the vascular endothelium on noradrenaline-induced contractions in non-pregnant and pregnant guinea-pig uterine arteries. Br J Pharmacol 114:805-815
18. Jovanović A, Jovanović S, Grbović L 1997 Endothelium-dependent relaxation in response to acetylcholine in pregnant guinea-pig uterine artery. Hum Reprod 12:1805-1809
19. Makino Y, Shibata K, Makino I, Kangawa K, Kawarabayashi T 2001 Alteration of the adrenomedullin receptor components gene expression associated with the blood pressure in pregnancy-induced hypertension. J Clin Endocrinol Metab 86:5079-5082 (Pubitemid 33020568)
20. Ross GR, Yallampalli C 2007 Vascular hyperresponsiveness to adrenomedullin during pregnancy is associated with increased generation of cyclic nucleotides in rat mesenteric artery. Biol Reprod 76:118-123
21. Ross GR, Chauhan M, Gangula PR, Reed L, Thota C, Yallampalli C 2006 Female sex steroids increase adrenomedullin-induced vasodilation by increasing the expression of adrenomedullin2 receptor components in rat mesenteric artery. Endocrinology 147:389-396
22. McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, Solari R, Lee MG, Foord SM 1998 RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393:333-339
23. Brain SD, Grant AD 2004 Vascular actions of calcitonin gene-related peptide and adrenomedullin. Physiol Rev 84:903-934 (Pubitemid 38823770)
24. Wang Y, Bukoski RD 1999 Use of acute phenolic denervation to show the neuronal dependence of Ca2+-induced relaxation of isolated arteries. Life Sci 64:887-894
25. Ichiki Y, Kitamura K, Kangawa K, Kawamoto M, Matsuo H, Eto T 1994 Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma. FEBS Lett 338:6-10
26. Nishikimi T 2005 Circulating adrenomedullin in cardiovascular disease. New York: Springer; 105-129
27. Nishimatsu H, Suzuki E, Nagata D, Moriyama N, Satonaka H, Walsh K, Sata M, Kangawa K, Matsuo H, Goto A, Kitamura T, Hirata Y 2001 Adrenomedullin induces endothelium-dependent vasorelaxation via the phosphatidylinositol 3-kinase/Akt-dependent pathway in rat aorta. Circ Res 89:63-70
28. Magness RR, Phernetton TM, Zheng J 1998 Systemic and uterine blood flow distribution during prolonged infusion of 17β-estradiol. Am J Physiol 275:H731-H743 (Pubitemid 28439760)
29. Challis JR, Harrison FA, Heap RB 1971 Uterine production of oestrogens and progesterone at parturition in the sheep. J Reprod Fertil 25:306-307
30. Magness RR, Rosenfeld CR, Carr BR 1991 Protein kinase C in uterine and systemic arteries during the ovarian cycle and pregnancy. Am J Physiol 260:E464-E470
31. Longo LD 1983 Maternal blood volume and cardiac output during pregnancy: a hypothesis of endocrinologic control. Am J Physiol 245:R720-R729
32. Magness RR, Rosenfeld CR 1989 Local and systemic estradiol-17 β: effects on uterine and systemic vasodilation. Am J Physiol 256:E536-E542
33. Magness RR, Phernetton TM, Zheng J 1998 Systemic and uterine blood flow distribution during prolonged infusion of 17β-estradiol. Am J Physiol 275:H731-H743
34. Ross GR, Yallampalli C 2006 Endothelium-independent relaxation by adrenomedullin in pregnant rat mesenteric artery: role of cAMP-dependent protein kinase A and calcium-activated potassium channels. J Pharmacol Exp Ther 317:1269-1275
35. Kawasaki H, Nuki C, Saito A, Takasaki K 1990 Adrenergic modulation of calcitonin gene-related peptide (CGRP) containing nerve-mediated vasodilation in the rat mesenteric resistance vessel. Brain Res 506:287-290 (Pubitemid 20031610)
36. Thota C, Gangula PR, Dong YL, Yallampalli C 2003 Changes in the expression of CRLR, RAMP1, RAMP2 and RAMP3 in rat uterus during pregnancy, labor and by steroid hormone treatments. Biol Reprod 69:1432-1437
37. Gangula PR, Thota CS, Wimalawansa SJ, Bukoski RD, Yallampalli C 2003 Mechanisms involved in calcitonin gene-related peptide-induced relaxation in pregnant rat uterine artery. Biol Reprod 69:1635-1641 (Pubitemid 37362848)
38. Watanabe H, Suzuki A, Mizutani T, Khono S, Lubahn DB, Handa H, Iguchi T 2002 Genome-wide analysis of changes in early gene expression induced by oestrogen. Genes Cells 7:497-507
39. Hay DL, Howitt SG, Conner AC, Schindler M, Smith DM, Poyner DR 2003 CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22-52, CGRP8-37 and BIBN4096BS. Br J Pharmacol 140:477-486
40. Hay DL, Conner AC, Howitt SG, Smith DM, Poyner DR 2004 The pharmacology of adrenomedullin receptors and their relationship to CGRP receptors. J Mol Neurosci 22:105-113
41. Weiner CP, Martinez E, Chestnut DH, Ghodsi A 1989 Effect of pregnancy on uterine and carotid artery response to norepinephrine, epinephrine, and phenylephrine in vessels with documented functional endothelium. Am J Obstet Gynecol 161:1605-1610
42. Sabates BL, Pigott JD, Choe EU, Cruz MP, Lippton HL, Hyman AL, Flint LM, Ferrara JJ 1997 Adrenomedullin mediates coronary vasodilation through adenosine receptors and KATP channels. J Surg Res 67:163-168
43. Chan W, Yao X, Ko W, Huang Y 2000 Nitric oxide mediated endothelium-dependent relaxation induced by glibenclamide in rat isolated aorta. Cardiovasc Res 46:180-187 (Pubitemid 30155958)
44. Langton PD, Nelson MT, Huang Y, Standen NB 1991 Block of calcium-activated potassium channels in mammalian arterial myocytes by tetraethylammonium ions. Am J Physiol 260:H927-H934