Maternal age-specific rates of fetal chromosomal abnormalities at 16-20 weeks' gestation in Korean pregnant women ≥35 years of age

Fetal Diagnosis and Therapy

Volumn 27, Issue 4, 2010, Pages 214-221

  Park, In Yang ^a   Kwon, Ji Young ^a   Kim, Yun Hee ^a   Kim, Myungshin ^b   Shin, Jong Chul ^a  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Amniocentesis; Chromosomal abnormalities; Genetic counseling; Trisomy 21

Indexed keywords

ADULT; AMNIOCENTESIS; ANEUPLOIDY; ARTICLE; CHROMOSOME ABERRATION; CYTOGENETICS; FEMALE; FETUS; GEOGRAPHIC DISTRIBUTION; GESTATION PERIOD; HUMAN; JAPAN; KARYOTYPE 47,XXX; KOREA; MAJOR CLINICAL STUDY; MATERNAL AGE; MOSAICISM; NORTH AMERICA; PREGNANT WOMAN; PREVALENCE; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; TRISOMY 18; TRISOMY 21; TURNER SYNDROME; UNITED KINGDOM;

ADULT; AGE FACTORS; AMNIOCENTESIS; CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; FEMALE; GESTATIONAL AGE; HUMANS; MATERNAL AGE; MIDDLE AGED; PREGNANCY; RISK FACTORS;

EID: 77956016088     PISSN: 10153837     EISSN: None     Source Type: Journal    
DOI: 10.1159/000309136     Document Type: Article

References (20)

1. Hook EB, Cross PK, Schreinemachers DM: Chromosomal abnormality rates at amniocentesis and in live-born infants. JAMA 1983; 249: 2034-2038.
2. Schreinemachers DM, Cross PK, Hook EB: Rates of trisomies 21, 18, 13 and other chromosome abnormalities in about 20,000 prenatal studies compared with estimated rates in live births. Hum Genet 1982; 61: 318-324.
3. Hook EB, Cross PK, Jackson L, Pergament E, Brambati B: Maternal age-specific rates of 47,+21 and other cytogenetic abnormalities diagnosed in the first trimester of pregnancy in chorionic villous biopsy specimens: comparison with rates expected from observations at amniocentesis. Am J Hum Genet 1988; 42: 797-807.
4. Yaegashi N, Senoo M, Uehara S, Suzuki H, Maeda T, Fujimori K, Hirahara F, Yajima A: Age-specific incidences of chromosome abnormalities at the second trimester amniocentesis for Japanese mothers aged 35 and older: collaborative study of 5484 cases. J Hum Genet 1998; 43: 85-90.
5. Ferguson-Smith MA, Yates JR: Maternal age specific rates for chromosome aberrations and factors influencing them: report of a collaborative european study on 52,965 amniocenteses. Prenat Diagn 1984; 4: 5-44.
6. American College of Obstetricians and Gynecologists: Antenatal Diagnosis of Genesis Disorders. Washington, American College of Obstetricians and Gynecologists, 1987, tech bull 108.
7. Snijders RJ, Sundberg K, Holzgreve W, Henry G, Nicolaides KH: Maternal age- and gestation-specific risk for trisomy 21. Ultrasound Obstet Gynecol 1999; 13: 167-170.
8. Halliday JL, Watson LF, Lumley J, Danks DM, Sheffield LJ: New estimates of Down syndrome risks at chorionic villous sampling, amniocentesis, and livebirth in women of advanced maternal age from a uniquely defined population. Prenat Diagn 1995; 15: 455-465.
9. Savva GM, Morris JK, Mutton DE, Alberman E: Maternal age-specific fetal loss rates in Down syndrome pregnancies. Prenat Diagn 2006; 26: 499-504.
10. Wapner RJ: Invasive prenatal diagnostic techniques. Semin Perinatol 2005; 29: 401-404.
11. Carothers AD, Collyer S, De Mey R, Frackiewicz A: Parental age and birth order in the aetiology of some sex chromosome aneuploidies. Ann Hum Genet 1978; 41: 277-287.
12. Hassold T, Abruzzo M, Adkins K, Griffin D, Merrill M, Millie E, Saker D, Shen J, Zaragoza M: Human aneuploidy: incidence, origin, and etiology. Environ Mol Mutagen 1996; 28: 167-175.
13. Dailey T, Dale B, Cohen J, Munné S: Association between nondisjunction and maternal age in meiosis-II human oocytes. Am J Hum Genet 1996; 59: 176-184.
14. Freeman SB, Allen EG, Oxford-Wright CL, Tinker SW, Druschel C, Hobbs CA, O'Leary LA, Romitti PA, Royle MH, Torfs CP, Sherman SL: The National Down Syndrome Project: design and implementation. Public Health Rep 2007; 122: 62-72.
15. Ghosh S, Feingold E, Dey SK: Etiology of Down syndrome: evidence for consistent association among altered meiotic recombination, nondisjunction, and maternal age across populations. Am J Med Genet 2009; 149: 1415-1420.
16. Druzin ML, Chervenak F, McCullough LB, Blatman RN, Neidich JA: Should all pregnant patients be offered prenatal diagnosis regardless of age? Obstet Gynecol 1993; 81: 615-618.
17. ACOG Committee on Practice Bulletins: ACOG Practice Bulletin No 77: Screening for fetal chromosomal abnormalities. Obstet Gynecol 2007; 109: 217-227.
18. Driscoll DA, Morgan MA, Schulkin J: Screening for Down syndrome: changing practice of obstetricians. Am J Obstet Gynecol 2009; 200: 459.e1-e9.
19. Hook EB, Cross PK, Regal RR: The frequency of 47,+21,47,+18, and 47,+13 at the uppermost extremes of maternal ages: results on 56,094 fetuses studied prenatally and comparisons with data on livebirths. Hum Genet 1984; 68: 211-220.
20. Evans MI, Sobiecki MA, Krivchenia EL, Duquette DA, Drugan A, Hume RF Jr, Johnson MP: Parental decisions to terminate/continue following abnormal cytogenetic prenatal diagnosis: 'what' is still more important than 'when'. Am J Med Genet 1996; 61: 353-355.