Age-specific incidences of chromosome abnormalities at the second trimester amniocentesis for Japanese mothers aged 35 and older: Collaborative study of 5484 cases

Journal of Human Genetics

Volumn 43, Issue 2, 1998, Pages 85-90

  Yaegashi, Nobuo ^a   Senoo, Masato ^a   Uehara, Shigeki ^a   Suzuki, Hisako ^a   Maeda, Tohru ^b   Fujimori, Keiya ^c   Hirahara, Fumiki ^d   Yajima, Akira ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Fukushima Pref College of Medicine   (Japan)

^d YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Advanced maternal age; Amniocentesis; Chromosome; Down syndrome; Prenatal diagnosis

Indexed keywords

AGE; AMNIOCENTESIS; ANEUPLOIDY; ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME DISORDER; COMPARATIVE STUDY; DOWN SYNDROME; FEMALE; FETUS DISEASE; GENETICS; HIGH RISK PREGNANCY; HUMAN; INCIDENCE; JAPAN; MATERNAL AGE; MOSAICISM; PREGNANCY; RISK; SEX CHROMOSOME ABERRATION; STATISTICAL MODEL; TRISOMY;

AGE FACTORS; AMNIOCENTESIS; ANEUPLOIDY; CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; DOWN SYNDROME; FEMALE; FETAL DISEASES; HUMANS; INCIDENCE; JAPAN; LOGISTIC MODELS; MATERNAL AGE; MOSAICISM; PREGNANCY; PREGNANCY, HIGH-RISK; RISK; SEX CHROMOSOME ABERRATIONS; TRISOMY;

EID: 0031626890     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100380050046     Document Type: Article

References (18)

1. Dailey T, Dale B, Cohen J, Munne S (1996) Association between nondisjunction and maternal age in meiosis-II human oocytes. Am J Hum Genet 59: 176-184
2. Ferguson-Smith MA, Yates JRW (1984) Maternal age specific rates for chromosome aberrations and factors influencing them: Report of a collaborative European study on 52.965 amniocenteses. Prenat Diagn 4: 5-44
3. Halliday JL, Watson LF, Lumley J, Danks DM, Sheffield LJ (1995) New estimates of Down syndrome risks at chorionic villus sampling, amniocentesis, and livebirth in women of advanced maternal age from a uniquely defined population. Prenat Diagn 15: 455-465
4. Hassold T, Abruzzo M, Adkins K, Griffin D, Merrill M, Millie E, Sakar D, Shen J, Zaragoza M (1996) Human aneuploidy incidence, origin, and etiology. Environ Mol Mutagen 28: 167-175
5. Hook EB (1983) Chromosome abnormalities and spontaneous fetal death following amniocentesis: Further data and associations with maternal age. Am J Hum Genet 35: 110-116
6. Hook EB, Cross PK, Regal RR (1984) The frequency of 47,+21, 47,+48, and 47,+43 at the uppermost extremes of maternal ages: results on 56,094 fetuses studied prenatally and comparisons with data on livebirths. Hum Genet 68, 211-220
7. Hook EB, Cross PK, Jackson L, Pergament E, Brambati B (1988) Maternal age-specific rates of 47,+21 and other cytogenetic abnormalities diagnosed in the first trimester of pregnancy in chorionic villus biopsy specimens Comparison with rates expected from observations at amniocentesis. Am J Hum Genet 42: 797-807
8. Hook EB, Topol BB, Cross PK (1989) The natural history of cytogenetically abnormal fetuses detected at midtrimester amniocentesis which are not terminated electively: New data and estimates of the excess and relative risk of late fetal death associated with 47,+21 and some other abnormal karyotypes Am J Hum Genet 45: 855-861
9. Lockwood DH, Neu RL (1993) Cytogenetic analysis of 1375 amniotic fluid specimens from pregnancies with gestational age less than 14 weeks. Prenat Diagn 13: 801-805
10. Macas E, Floersheim Y, Hotz E, Imthurn B, Keller PJ, Walt H (1990) Abnormal chromosomal arrangements in human oocytes. Hum Reprod 5: 703-707
11. Macintosh MCM, Wald NJ, Chard T, Hansen J, Mikkelsen M, Therkelsen AJ, Petersen GB, Lundsteen C (1995) Selective miscarriage of Down's syndrome fetuses in women aged 35 years and older. Br J Obstet Gynaecol 102: 798-801
12. Maeda T, Ohno M, Matsunobu A, Yoshihara K, Yabe N (1991) A cytogenetic survey of 14,835 consecutive liveborns. Jpn J Human Genet 36: 117-129
13. Mother's and Children's Health Organization (1996) Live births by age of mother. In: Mother's and Children's Health and Welfare Association (ed) Maternal and child health statistics of Japan 1996. Tokyo, pp 47-53
14. Mutton DE, Alberman E, Ide R, Bobrow M (1991) Results of first year (1989) of a national register of Down's syndrome in England and Wales. Br Med J 303: 1295-1297
15. The NICHD National Registry for Amniocentesis Study Group (1976) Midtrimester amniocentesis for prenatal diagnosis: Safety and accuracy. JAMA 236: 1471-1476
16. Plachot M, de Grouchy J, Junca AM, Mandelbaum J, Salat-Baroux J, Cohen J (1988) Chromosome analysis of human oocytes and embryos: does delayed fertilization increase chromosome imbalance? Hum Reprod 3: 125-127
17. Polani PE, Alberman E, Berry AC, Blunt S. Singer JD (1976) Chromosome abnormalities and maternal age. Lancet II: 516-517
18. Schreinemachers DM, Cross PK, Hook EB (1982) Rates of trisomies 21, 18, 13 and other chromosome abnormalities in about 20,000 prenatal studies compared with estimated rates in live births. Hum Genet 61: 318-324