Upregulation of human leukocyte antigen-G expression and its clinical significance in ductal breast cancer

Human Immunology

Volumn 71, Issue 9, 2010, Pages 892-898

  Chen, Hai Xiao ^a   Lin, Aifen ^a   Shen, Chao Jun ^a   Zhen, Rui ^a   Chen, Bao Guo ^a   Zhang, Xia ^a   Cao, Fei Ling ^a   Zhang, Jian Gang ^a   Yan, Wei Hua ^a  

^a TAIZHOU HOSPITAL OF ZHEJIANG PROVINCE   (China)

Author keywords

Breast cancer; HLA G; Regulatory T cell; Soluble HLA G

Indexed keywords

HLA G ANTIGEN; TRANSCRIPTION FACTOR FOXP3;

ANTIGEN EXPRESSION; ARTICLE; BREAST CANCER; CANCER STAGING; CD4+ CD25+ T LYMPHOCYTE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; UPREGULATION;

ADULT; BIOLOGICAL MARKERS; BREAST NEOPLASMS; CARCINOMA, DUCTAL; CELL COUNT; CELL MEMBRANE; CYTOPLASM; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; MIDDLE AGED; NEOPLASM STAGING; ROC CURVE; SENSITIVITY AND SPECIFICITY; T-LYMPHOCYTES, REGULATORY; UP-REGULATION;

EID: 77956011661     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2010.06.009     Document Type: Article

References (38)

1. Pittet M.J. Behavior of immune players in the tumor microenvironment. Curr Opin Oncol 2009, 21:53-59.
2. Algarra I., García-Lora A., Cabrera T., Ruiz-Cabello F., Garrido F. The selection of tumor variants with altered expression of classical and nonclassical MHC class I molecules: Implications for tumor immune escape. Cancer Immunol Immunother 2004, 53:904-910.
3. Nizar S., Copier J., Meyer B., Bodman-Smith M., Galustian C., Kumar D., et al. T-regulatory cell modulation: The future of cancer immunotherapy?. Br J Cancer 2009, 100:1697-1703.
4. Urosevic M., Dummer R. Human leukocyte antigen-G and cancer immunoediting. Cancer Res 2008, 68:627-630.
5. Kovats S., Main E.K., Librach C., Stubblebine M., Fisher S.J., DeMars R. A class I antigen, HLA-G, expressed in human trophoblasts. Science 1990, 248:220-223.
6. Crisa L., McMaster M.T., Ishii J.K., Fisher S.J., Salomon D.R. Identification of a thymic epithelial cell subset sharing expression of the class Ib HLA-G molecule with fetal trophoblasts. J Exp Med 1997, 186:289-298.
7. Le Discorde M., Moreau P., Sabatier P., Legeais J.M., Carosella E.D. Expression of HLA-G in human cornea, an immune-privileged tissue. Hum Immunol 2003, 64:1039-1044.
8. Ito T., Ito N., Saathoff M., Stampachiacchiere B., Bettermann A., Bulfone-Paus S., et al. Immunology of the human nail apparatus: The nail matrix is a site of relative immune privilege. J Invest Dermatol 2005, 125:1139-1148.
9. Cirulli V., Zalatan J., McMaster M., Prinsen R., Salomon D.R., Ricordi C., et al. The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G. Diabetes 2006, 55:1214-1222.
10. Menier C., Rabreau M., Challier J.C., Le Discorde M., Carosella E.D., Rouas-Freiss N. Erythroblasts secrete the nonclassical HLA-G molecule from primitive to definitive hematopoiesis. Blood 2004, 104:3153-3160.
11. Selmani Z., Naji A., Zidi I., Favier B., Gaiffe E., Obert L., et al. Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells. Stem Cells 2008, 26:212-222.
12. Carosella E.D., Moreau P., Lemaoult J., Rouas-Freiss N. HLA-G: From biology to clinical benefits. Trends Immunol 2008, 29:125-132.
13. Paul P., Rouas-Freiss N., Khalil-Daher I., Moreau P., Riteau B., Le Gal F.A., et al. HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance. Proc Natl Acad Sci U S A 1998, 95:4510-4515.
14. Tripathi P., Agrawal S. Non-classical HLA-G antigen and its role in the cancer progression. Cancer Invest 2006, 24:178-186.
15. Shih IeM. Application of human leukocyte antigen-G expression in the diagnosis of human cancer. Hum Immunol 2007, 68:272-276.
16. Li B.L., Lin A., Zhang X.J., Zhang X., Zhang J.G., Wang Q., et al. Characterization of HLA-G expression in renal cell carcinoma. Tissue Antigens 2009, 74:213-221.
17. Ishitani A., Geraghty D.E. Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens. Proc Natl Acad Sci U S A 1992, 89:3947-3951.
18. Paul P., Cabestre F.A., Ibrahim E.C., Lefebvre S., Khalil-Daher I., Vazeux G., et al. Identification of HLA-G7 as a new splice variant of the HLA-G mRNA and expression of soluble HLA-G5, -G6, and -G7 transcripts in human transfected cells. Hum Immunol 2000, 61:1138-1149.
19. Rebmann V., Busemann A., Lindemann M., Grosse-Wilde H. Detection of HLA-G5 secreting cells. Hum Immunol 2003, 64:1017-1024.
20. Pistoia V., Morandi F., Wang X., Ferrone S. Soluble HLA-G: Are they clinically relevant?. Semin Cancer Biol 2007, 17:469-479.
21. Carosella E.D., HoWangYin K.Y., Favier B., LeMaoult J. HLA-G-dependent suppressor cells: Diverse by nature, function, and significance. Hum Immunol 2008, 69:700-707.
22. LeMaoult J., Krawice-Radanne I., Dausset J., Carosella E.D. HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4+ T cells. Proc Natl Acad Sci USA 2004, 101:7064-7069.
23. Curiel T.J. Tregs and rethinking cancer immunotherapy. J Clin Invest 2007, 117:1167-1174.
24. Sobin L.H., Wittekind C. TNM Classification of Malignant Tumors 2002, Wiley-Liss, New York, (eds). (ed 6).
25. Lin A., Zhu C.C., Chen H.X., Chen B.F., Zhang X., Zhang J.G., et al. Clinical relevance and functional implications for human leukocyte antigen-G expression in non-small-cell lung cancer. J Cell Mol Med 2009, doi:10.1111/j.1582-4934.2009.00858.x.
26. Yie S.M., Yang H., Ye S.R., Li K., Dong D.D., Lin X.M. Expression of human leucocyte antigen G (HLA-G) is associated with prognosis in non-small cell lung cancer. Lung Cancer 2007, 58:267-274.
27. Yie S.M., Yang H., Ye S.R., Li K., Dong D.D., Lin X.M. Expression of human leukocyte antigen G (HLA-G) correlates with poor prognosis in gastric carcinoma. Ann Surg Oncol 2007, 14:2721-2729.
28. Yie S.M., Yang H., Ye S.R., Li K., Dong D.D., Lin X.M. Expression of HLA-G is associated with prognosis in esophageal squamous cell carcinoma. Am J Clin Pathol 2007, 128:1002-1009.
29. Nückel H., Rebmann V., Dürig J., Dührsen U., Grosse-Wilde H. HLA-G expression is associated with an unfavorable outcome and immunodeficiency in chronic lymphocytic leukemia. Blood 2005, 105:1694-1698.
30. Palmisano G.L., Pistillo M.P., Fardin P., Capanni P., Nicolò G., Salvi S., et al. Analysis of HLA-G expression in breast cancer tissues. Hum Immunol 2002, 63:969-976.
31. Lefebvre S., Antoine M., Uzan S., McMaster M., Dausset J., Carosella E.D., et al. Specific activation of the non-classical class I histocompatibility HLA-G antigen and expression of the ILT2 inhibitory receptor in human breast cancer. J Pathol 2002, 196:266-274.
32. Kleinberg L., Flørenes V.A., Skrede M., Dong H.P., Nielsen S., McMaster M.T., et al. Expression of HLA-G in malignant mesothelioma and clinically aggressive breast carcinoma. Virchows Arch 2006, 449:31-39.
33. Singer G., Rebmann V., Chen Y.C., Liu H.T., Ali S.Z., Reinsberg J., et al. HLA-G is a potential tumor marker in malignant ascites. Clin Cancer Res 2003, 9:4460-4464.
34. He X., Dong D.D., Yie S.M., Yang H., Cao M., Ye S.R., et al. HLA-G expression in human breast cancer: Implications for diagnosis and prognosis, and effect on allocytotoxic lymphocyte response after hormone treatment in vitro. Ann Surg Oncol 2010, 17:1459-1469.
35. Cai M.Y., Xu Y.F., Qiu S.J., Ju M.J., Gao Q., Li Y.W., et al. Human leukocyte antigen-G protein expression is an unfavorable prognostic predictor of hepatocellular carcinoma following curative resection. Clin Cancer Res 2009, 15:4686-4693.
36. Giannopoulos K., Schmitt M., Kowal M., Wlasiuk P., Bojarska-Junak A., Chen J., et al. Characterization of regulatory T cells in patients with B-cell chronic lymphocytic leukemia. Oncol Rep 2008, 20:677-682.
37. Le Maux A., Noël G., Birebent B., Grosset J.M., Vu N., De Guibert S., et al. Soluble human leucocyte antigen-G molecules in peripheral blood haematopoietic stem cell transplantation: A specific role to prevent acute graft-versus-host disease and a link with regulatory T cells. Clin Exp Immunol 2008, 152:50-56.
38. Rudstein-Svetlicky N., Loewenthal R., Horejsi V., Gazit E. HLA-G levels in serum and plasma. Tissue Antigens 2006, 67:111-116.