Identification of QTL for dorso-caudal chronic pleuritis in 12 crossbred porcine families

Animal Genetics

Volumn 41, Issue 5, 2010, Pages 509-514

  Gregersen, V R ^a   Sorensen K K ^a   Christensen, O F ^a   Busch, M E ^b   Vingborg, R K K ^a   Velander, I H ^b   Lund, M S ^a   Bendixen, C ^a  

^a DANISH INSTITUTE OF AGRICULTURAL SCIENCES   (Denmark)

^b Pig Research Centre   (Denmark)

Author keywords

Actinobacillus pleuropneumoniae; lung lesions; pig breeding; pleuropneumonia; single nucleotide polymorphism; Sus scrofa; swine respiratory disease

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; CROSS BREEDING; FEMALE; GENETICS; IMMUNOLOGY; LUNG; MALE; MICROBIOLOGY; PATHOLOGY; PLEURISY; PNEUMONIA; QUANTITATIVE TRAIT LOCUS; SWINE; SWINE DISEASE; VIROLOGY;

ANIMALS; CROSSES, GENETIC; FEMALE; LUNG; MALE; PLEURISY; PLEUROPNEUMONIA; QUANTITATIVE TRAIT LOCI; SUS SCROFA; SWINE DISEASES;

ACTINOBACILLUS PLEUROPNEUMONIAE; MYCOPLASMA; PIERIS BRASSICAE; SUIDAE; SUS; SUS SCROFA;

EID: 77956000204     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2010.02028.x     Document Type: Article

References (36)

1. Andreasen M., Mousing J. Thomsen L.K. (2001) No simple association between time elapsed from seroconversion until slaughter and the extent of lung lesions in Danish Swine. Preventive Veterinary Medicine 52, 147 161.
2. Bates D., Maechler M. Dai B. (2008) lme4: linear mixed-effects models using S4 classes. R package version 0.999375-28. http://lme4.r-forge.r-project. org/.
3. Bruch J., Rettenberger G., Leeb T., Meier-Ewert S., Klett C., Brenig B. Hameister H. (1996) Mapping of type I loci from human chromosome 7 reveals segments of conserved synteny on pig chromosomes 3, 9, and 18. Cytogenetics and Cell Genetics 73, 164 167. (Pubitemid 26257834)
4. Cho W.-S., Jung K., Kim J., Ha Y. Chae C. (2005) Expression of mRNA encoding interleukin (IL)-10, IL-12p35 and IL-12p40 in lungs from pigs experimentally infected with Actinobacillus pleuropneumoniae. Veterinary Research Communication 29, 111 122.
5. Christensen G. (1981) Pleuropneumonia in swine due to Haemophilus pleuropneumonia s. parahaemolyticus. II. Studies on the epidemiology and the relation to chronic pleuritis (pleural scars) in baconers. Nordisk Veterinaermedicin 33, 236 249.
6. Christensen G. Enø C. (1999) Forekomst af forandringer i pluckset af danske slagtesvin. (The prevalence of pneumonia, pleuritis, pericarditis and liver spots in Danish slaughter pigs in 1998, including comparation with 1994). Dansk Veterinærtidsskrift 82, 1006 1015.
7. Christensen O.F., Busch M.E., Gregersen V.R., Lund M.S., Nielsen B., Vingborg R.K.K. Bendixen C. (2010) Quantitative trait loci analysis of osteochondrosis traits in the elbow joint of pigs. Animal 4, 417 424
8. Cleveland-Nielsen A., Nielsen E.O. Ersbøll A.K. (2002) Chronic pleuritis in Danish slaughter pig herds. Preventive Veterinary Medicine 55, 121 135.
9. Danilowicz E., Akouchekian M., Drögemüller C., Haase B., Kuiper H., Distl O., Leeb T. FUGATO-consortium IRAS (2008) Molecular characterization and SNP development for the porcine IL6 and IL10 genes. Animal Biotechnology 19, 159 165.
10. Enøe C., Mousing J., Schirmer A.L. Willeberg P. (2002) Infectious and rearing-system related risk factors for chronic pleuritis in slaughter pigs. Preventive Veterinary Medicine 54, 337 349.
11. Frydendahl K., Jensen T.K., Andersen J.S., Fredholm M. Evans G. (2003) Association between the porcine Escherichia coli F18 receptor genotype and susceptibility to colonisation and postweaning diarrhoea caused by E. coli O138:F18. Veterinary Microbiology 93, 39 51.
12. Green P., Falls K. Crooks S. (1990) Documentation for crimap v. 2.4. Washington University School of Medicine, St. Louis, MO.
13. Guldbrandtsen B. Labouriau R. (2006) Confirming QTL. 8th World Congress on Genetics Applied to Livestock Production. August 13-18, Belo Horizonte, MG, Brasil, 22 6.
14. Halbur P.G. (1998) Porcine respiratory disease. Proceedings of the International Pig Veterinary Society Congress 15, 1 10.
15. Hedegaard J., Skovgaard K., Mortensen S., Sørensen P., Jensen T.K., Hornshøj H., Bendixen C. Heegaard P.M.H. (2007) Molecular characterisation of the early response in pigs to experimental infection with Actinobacillus pleuropneumoniae using cDNA microarrays. Acta Veterinaria Scandinavica 49, 11.
16. Henryon M., Berg P., Jensen J. Andersen S. (2001) Genetic variation for resistance to clinical and subclinical diseases exists in growing pigs. Animal Science 73, 375 387. (Pubitemid 33390153)
17. Jackson P.G.G. Cockcroft P.D. (2007) Diseases of the respiratory system. In : Handbook of Pig Medicine (Eds by P.G.G. Jackson P.D. Cockcroft pp. 70 82. Saunders, Elsevier, Philadelphia, PA.
18. Jensen G.M., Frydendahl K., Svendsen O., Jørgensen D.B., Cirera S., Fredholm M., Nielsen J.-P. Møller K. (2006) Experimental infection with Escherichia coli O149:F4ac in weaned piglets. Veterinary Microbiology 115, 243 249.
19. Jirawattanapong P., Stockhofe-Zurwieden N., van Leengoed L., Binnendijk G., Wisselink H.J., Raymakers R., Cruijsen T., van der Peet-Schwering C., van Nes A. Nielen M. (2008) Efficacy of a subunit vaccine against Actinobacillus pleuropneumoniae in an endemically infected swine herd. Journal of Swine Health and Production 16, 193 199.
20. Joller D., Jørgensen C.B., Bertschinger H.U. et al. (2009) Refined localization of the Escherichia coli F4ab/F4ac receptor locus on pig chromosome 13. Animal Genetics 40, 749 752.
21. Jørgensen B. Nielsen B. (2005) Genetic parameters for osteochondrosis traits in elbow joints of crossbred pigs and relationships with production traits. Animal Science 81, 319 324.
22. Jørgensen C.B., Cirera S., Archibald A.L., Andersson L., Fredholm M. Edfors-Lilja I. (2004) Porcine polymorphisms and methods for detecting them. International application published under the patent cooperation treaty (PCT). PCT/DK2003/000807 or WO2004/048606-A2.
23. Jørgensen F.G., Hobolth A., Hornshøj H., Bendixen C., Fredholm M. Schierup M.H. (2005) Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. BMC Biology 3, 2.
24. McIntyre L.M., Martin E.R., Simonsen K.L. Kaplan N.L. (2000) Circumventing multiple testing: a multilocus Monte Carlo approach to testing for association. Genetic Epidemiology 19, 18 29.
25. Meijerink E., Neuenschwander S., Fries R., Dinter A., Bertschinger H.U., Stranzinger G. Vögeli P. (2000) A DNA polymorphism influencing α(1,2)fucosyltransferase activity of the pig FUT1 enzyme determines susceptibility of small intestinal epithelium to Escherichia coli F18 adhesion. Immunogenetics 52, 129 136.
26. Mousing J., Lybye H., Barfod K., Meyling A., Rønsholt L. Willeberg P. (1990) Chronic pleuritis in pigs for slaughter: an epidemiological study of infectious and rearing system-related risk factors. Preventive Veterinary Medicine 9, 107 119.
27. Myers M.J., Farrell D.E., Snider T.G.R. III. Post L.O. (2004) Inflammatory cytokines, pleuropneumonia infection and the effect of dexamethasone. Pathobiology 71, 35 42.
28. Panitz F., Stengaard H., Hornshøj H. et al. (2007) SNP mining porcine ESTs with MAVIANT, a novel tool for SNP evaluation and annotation. Bioinformatics 23, i387 91.
29. Piepho H.-P. (2001) A quick method for computing approximate thresholds for quantitative trait loci detection. Genetics 157, 425 432.
30. Reiner G., Melchinger E., Kramarova M., Pfaff E., Büttner M., Saalmüller A. Geldermann H. (2002) Detection of quantitative trait loci for resistance/susceptibility to pseudorabies virus in swine. Journal of General Virology 83, 167 172.
31. Reiner G., Kliemt D., Willems H. et al. (2007) Mapping of quantitative trait loci affecting resistance/susceptibility to Sarcocystis miescheriana in swine. Genomics 89, 638 646.
32. Sambrook J., Fritsch E.F. Maniatis T. 1989) Analysis and cloning of eukaryotic genomic DNA. In : Molecular Cloning: A Laboratory Manual (Eds by N. Ford, C. Nolan M. Ferguson pp. 9.16 9.19. Cold Spring Harbor Laboratory Press, New York, NY.
33. Sørensen P., Lund M.S., Guldbrandtsen B., Jensen J. Sorensen D. (2003) A comparison of bivariate and univariate QTL mapping in livestock populations. Genetics Selection Evolution 35, 605 622.
34. Sørensen V., Jorsal S.E. Mousing J. (2006) Diseases of the respiratory system. In : Diseases of Swine, 9th edn (Eds by B.E. Straw, J.J. Zimmerman, S. D'Allaire D.J. Taylor pp. 149 177. Blackwell Publishing, Ames, IA.
35. Straw B.E., Tuovinen V. Bigras-Poulin M. (1989) Estimation of the cost of pneumonia in swine herds. Journal of the American Veterinary Medical Association 195, 1702 1706.
36. Vingborg R.K.K., Gregersen V.R., Zhan B. et al. (2009) A robust linkage map of the porcine autosomes based on gene-associated SNPs. BMC Genomics 10, 134.