Gene expression modifications in the liver caused by binge drinking and S-adenosylmethionine feeding. The role of epigenetic changes

Genes and Nutrition

Volumn 5, Issue 2, 2010, Pages 169-179

  Li, Jun ^a   Bardag Gorce, Fawzia ^a   Oliva, Joan ^a   Dedes, Jennifer ^a   French, Barbara A ^a   French, Samuel W ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

Binge drinking; Epigenetic memory; Methyl donor; S adenosylmethionine

Indexed keywords

ADENOSYLHOMOCYSTEINASE; ALANINE AMINOTRANSFERASE; ALCOHOL; BETAINE HOMOCYSTEINE METHYLTRANSFERASE; FORKHEAD TRANSCRIPTION FACTOR; GLUCOSE; HISTONE; HISTONE ACETYLTRANSFERASE PCAF; INSULIN; METHIONINE ADENOSYLTRANSFERASE; PROTEIN C JUN; S ADENOSYLMETHIONINE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TUMOR NECROSIS FACTOR RECEPTOR;

ALCOHOL CONSUMPTION; ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DNA MODIFICATION; DOWN REGULATION; DRINKING BEHAVIOR; EPIGENETICS; GENE EXPRESSION REGULATION; GENE SILENCING; MALE; MICROARRAY ANALYSIS; NONHUMAN; PROTEIN FUNCTION; PROTEIN METHYLATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

RATTUS;

EID: 77955984804     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-009-0158-x     Document Type: Article

References (10)

1. Bardag-Gorce F, French B, Li J, Dedes J, French SW (2009) Chronic Ethanol feeding alters hepatocyte memory which is not altered by acute feeding. Alcoholism Clin Exp Res 33:684-692
2. Bardag-Gorce F, French BA, Joyce M, Baires M, Montgomery RO, Li J, French SW (2007) Histone acetyltransferase p300 modulates gene expression in an epigenetic manner at high blood alcohol levels. Exp Mol Pathol 82:197-202
3. Oliva J, French BA, Li J, Bardag-Gorce F, Fu P, French SW (2008) Sirt is involved in energy metabolism. The role of chronic ethanol feeding and resveratrol. Exp Mol Pathol 85:155-159
4. Shukla SD, Velazquez J, French SW, Lu SC, Ticku MK, Zakhari S (2008) Emerging role of epigenetic in the actions of alcohol. Alcoholism Clin Exp Res 32:525-1534
5. Bardag-Gorce F, Oliva J, Villegas J, Fraley S, Amidi F, Li J, Dedes J, French B, French SW (2008) Epigenetic mechanisms regulate Mallory Denk body formation in the livers of drugprimed mice. Exp Mol Pathol 84:113-121
6. Zakhari S, Li T-K (2007) Determinants of alcohol use and abuse: Impact of quality and frequency patterns on liver disease. Hepathology 46:2032-2039
7. Pal-Bhadra M, Bhadra U, Jackson DE, Mamatha L, Park P, Shukla SD (2007) Ethanol and chromatin remodeling histone H3 methylation at lys-4 and lys-9 correlates with up and down regulation of genes in rat hepatocytes. Alcoholism Clin Exp Res 31:13A
8. Li J, Bardag-Gorce F, Dedes J, French BA, Amidi F, Oliva J, French SW (2008) S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory. Hepatology 47:613-624
9. Ara AI, Xia M, Ramani K, Mato JM, Lu SC (2008) S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation. Hepatology 47:1655-1666
10. Gobyishvilli L, Barve S, Joshi-Barve S, Uriarte S, Song Z, McClain C (2006) Chronic ethanol-mediated decrease in cAMP primers macrophages to enhanced LPS-inducible NF-jB activity and TNF expression: relevance to alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol 291:G681-G888