The antiapoptotic effects of blood constituents in patients with chronic lymphocytic leukemia

European Journal of Haematology

Volumn 70, Issue 5, 2003, Pages 290-295

  Bomstein, Yonit ^a   Yuklea, Mona ^a   Radnay, Judith ^a   Shapiro, Hava ^a   Afanasyev, Faina ^a   Yarkoni, Shai ^a   Lishner, Michael ^a  

^a MEIR MEDICAL CENTER   (Israel)

Author keywords

Apoptosis; Chronic lymphocytic leukemia; In vitro

Indexed keywords

ADULT; AGED; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BLOOD COMPONENT; CANCER CELL; CELL DEATH; CELL ISOLATION; CELL SURVIVAL; CELLULAR IMMUNITY; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; DISEASE COURSE; FETAL CALF SERUM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; INCUBATION TIME; LYMPHOCYTE SUBPOPULATION; MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE;

AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, CD19; APOPTOSIS; B-LYMPHOCYTES; CASE-CONTROL STUDIES; CATTLE; CELL SURVIVAL; CULTURE MEDIA; HUMANS; LEUKEMIA, B-CELL, CHRONIC; MIDDLE AGED; NEOPLASM STAGING; T-LYMPHOCYTES;

EID: 0037542686     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0609.2003.00063.x     Document Type: Article

References (34)

1. KIPPS TJ. Chronic lymphocytic leukemia. Curr Opin Hematol 2000;7:223-234.
2. BANNERJI R, BYRD JC. Update on the biology of chronic lymphocytic leukemia. Curr Opin Oncol 2000;12:22-29.
3. CALIGARIS-CAPPIO F, HAMBLIN TJ. B-cell chronic lymphocytic leukemia: a bird of a different feather. J Clin Oncol 1999;17:399-408.
4. DORMER P, THEML H, LAU B. Chronic lymphocytic leukemia: a proliferative or accumulative disorder? Leuk Res 1983;7:1-10.
5. GAIDANO G, NEWCOMB EW, GONG JZ, TASSI V, NERI A, CORTELEZZI A, CALORI R, BALDINI L, DALLA-FAVERA R. Analysis of alterations of oncogenes and tumor suppressor genes in chronic lymphocytic leukemia. Am J Pathol 1994;144:1312-1319.
6. AGULAR-SANTELISES M, ROTTENBERG ME. Bcl-2, Bax and p53 expression in B-CLL in relation to in vitro survival and clinical progression. Int J Cancer 1996;69:114-119.
7. LISHNER M, LALKIN A, KLEIN A, YARKONI S, MANOR Y, FEJGIN M, LEYTIN V, RAVID M, AMIEL A. THE BCL-1, BCL-2, and BCL-3 oncogenes are involved in chronic lymphocytic leukemia. Detection by fluorescence in situ hybridization. Cancer Genet Cytogenet 1995;85:118-123.
8. LAGNEAUX L, DELFORGE A, DORVAL C, BRON D, STRYCKMANS P. Excessive production of transforming growth factor-beta by bone marrow stromal cells in B-cell chronic lymphocytic leukemia inhibits growth of hematopoietic precursors and interleukin-6 production. Blood 1993;82:2379-2385.
9. PANAYIOTIDIS P, JONES D, GANESHAGURU K, FORONI L, HOFFBRAND AV. Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro. Br J Haematol 1996;92:97-103.
10. LAGNEAUX L, DELFORGE A, BRON D, DE BRUYN C, STRYCKMANS P. Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells. Blood 1998;91:2387-2396.
11. BURGER JA, BURGER M, KIPPS TJ. Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate sponaneous migration beneath bone marrow stromal cells. Blood 1999;94:3658-3667.
12. LEVENS JM, GORDON J, GREGORY CD. Micro-environmental factors in the survival of human B-lymphoma cells. Cell Death Differ 2000;7:59-69.
13. BURGER JA, TSUKADA N, BURGER M, ZVAIFLER NJ, DELL'AQUILA M, KIPPS TJ. Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood 2000;96:2655-2663.
14. STROBEL ES, STROBEL HG, BROSS KJ, WINTERHALTER B, FIEBIG HH, SCHILDGE JU, LOHR G.W. Effects of human bone marrow stroma on the growth of human tumor cells. Cancer Res 1989;49:1001-1007.
15. MORENO A, VILLAR ML, CAMARA C, LUQUE R, CESPON C, GONZALEZ-PORQUE P, ROY G, LOPEZ-JIMENEZ J, BOOTELLO A. Interleukin-6 dimers produced by endothelial cells inhibit apoptosis of B-chronic lymphocytic leukemia cells. Blood 2001;97:242-249.
16. CASTEJON R, VARGAS JA, ROMERO Y, BRIZ M, MUNOZ RM, DURANTEZ A. Modulation of apoptosis by cytokines in B-cell chronic lymphocytic leukemia. Cytometry 1999;38:224-230.
17. FRANCIA DI CELLE P, MARIANI S, RIERA L, STACCHINI A, REATO G, FOA R. Interleukin-8 induces the accumulation of B-cell chronic lymphocytic leukemia cells by prolonging survival in an autocrine fashion. Blood 1996;87:4382-4389.
18. CHAOUCHI N, WALLON C, GOUJARD C, TERTIAN G, RUDENT A, CAPUT D, FERRERA P, MINTY A, VAZQUEZ A, DELFRAISSY JF. Interleukin-13 inhibits interleukin-2-induced proliferation and protects chronic lymphocytic leukemia B cells from in vitro apoptosis. Blood 1996;87:1022-1029.
19. PANAYIOTIDIS P, GANESHAGURU K, JABBAR SA, HOFFBRAND AV. Alpha-interferon (alpha-IFN) protects B-chronic lymphocytic leukaemia cells from apoptotic cell death in vitro. Br J Haematol 1994;86:169-173.
20. ROJAS R, ROMAN J, TORRES A, RAMIREZ R, CARRACEDO J, LOPEZ R, GARCIA JM, MARTIN C, PINTADO O. Inhibition of apoptotic cell death in B-CLL by interferon gamma correlates with clinical stage. Leukemia 1996;10:1782-1788.
21. COLLINS RJ, VERSCHUER LA, HARMON BV, PRENTICE RL, POPE JH, KERR JF. Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro. Br J Haematol 1989;71:343-350.
22. KULMBURG P, RADKE M, DIGEL W. Lymphotoxin-alpha is an autocrine growth factor for chronic lymphocytic leukemia B cells. Leukemia 1989;12:493-498.
23. REITTIE JE, YONG KL, PANAYIOTIDIS P, HOFFBRAND AV. Interleukin-6 inhibits apoptosis and tumour necrosis factor induced proliferation of B-chronic lymphocytic leukaemia. Leuk Lymphoma 1996;22:83-90.
24. KAY NE, HAN L, BONE N, WILLIAMS G. Interleukin 4 content in chronic lymphocytic leukaemia (CLL) B cells and blood CD8+ T cells from B-CLL patients: impact on clonal B-cell apoptosis. Br J Haematol 2001;112:760-767.
25. SINICROPE FA, RODDEY G, MCDONNELL TJ, SHEN Y, CLEARY KR, STEPHENS LC. Increased apoptosis accompanies neoplastic development in the human colorectum. Clin Cancer Res 1996;2:1999-2006.
26. DONIN N, KAY S, SINAI J, KATZENELSON D, SIEGAL A, MICHOWITZ M, SCHIBI G, LEIBOVICI J. Apoptosis and cell proliferation capacity in AKR lymphoma malignancy variants. Cancer Invest 2000;18:702-714.
27. DECKER T, FLOUR T, TRAUTMANN P, AMAN MJ, HOLTER W, MAJDIC O, HUBER C, PESCHEL C. Role of accessory cells in cytokine production by T cells in chronic B-cell lymphocytic leukemia. Blood 1995;86:1115-1123.
28. BUHMANN R, NOLTE A, WESTHAUS D, EMMERICH B, HALLEK M. CD40-activated B-cell chronic lymphocytic leukemia cells for tumor immunotherapy: stimulation of allogeneic versus autologous T cells generates different types of effector cells. Blood 1999;93:1992-2000.
29. TINHOFER I, MARSCHITZ I, KOS M, HENN T, EGLE A, VILLUNGER A, GREIL R. Differential sensitivity of CD4+ and CD8+ T lymphocytes to the killing efficacy of Fas (Apo-1/CD95) ligand+ tumor cells in B chronic lymphocytic leukemia. Blood 1998;91:4273-4281.
30. TRETTER T, SCHULER M, SCHNELLER F, BRASS U, ESSWEIN M, AMAN M, HUBER C, PESCHEL C. Direct cellular interaction with activated CD4 (+) T cells overcomes hyporesponsiveness of B-cell chronic lymphocytic leukemia in vitro. Cell Immunol 1998;189:41-50.
31. GOTTARDI D, ALFARANO A, DE LEO AM, STACCHINI A, ARAGNO M, RICO A, VENERI D, ZANOTTI R, PIZZOLO G, CALIGARIS-CAPPIO F. In leukaemic CD5+ B cells the expression of BCL-2 gene family is shifted toward protection from apoptosis. Br J Haematol 1996;94:612-618.
32. LAYTRAGOON-LEWIN N, DUHONY E, BAI XF, MELLSTEDT H. Downregulation of the CD95 receptor and defective CD40-mediated signal transduction in B-chronic lymphocytic leukemia cells. Eur J Haematol 1998;61:266-271.
33. YOUNES A, SNELL V, CONSOLI U, CLODI K, ZHAOS, PALMER JL, THOMAS EK, ARMITAGE RJ, ANDREEFF M. Elevated levels of biologically active soluble CD40 ligand in the serum of patients with chronic lymphocytic leukaemia. Br J Haematol 1998;100:135-141.
34. YOUNES A. The dynamics of life and death of malignant lymphocytes. Curr Opin Oncol 1999;11:364-369.