Synthesis of the azetidinyl-thiazoline fragment of vioprolides A and C

Letters in Organic Chemistry

Volumn 7, Issue 5, 2010, Pages 353-359

  Chopin, Nathalie ^a   Couty, François ^a   Evano, Gwilherm ^a  

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

Author keywords

Antifungal metabolites; Azetidines; Natural products

Indexed keywords

EID: 77955970832     PISSN: 15701786     EISSN: None     Source Type: Journal    
DOI: 10.2174/157017810791514814     Document Type: Article

References (10)

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2. For similar condensations, see a) Iyengar, B. S.; Dorr, R. T.; Remers, W.; A. Chemical basis for the biological activity of Imexon and related cyanoaziridines. J. Med. Chem. 2004, 47, 218.
3. b) Zhou, W.; Shultz, J. W.; Murphy, N.; Hawkins, E. M.; Bernad, L.; Good, T.; Moothart, L.; Frackman, S.; Klaubert, D. H.; Bulleit, R. F.; Wood, K. V. Electrophilic aromatic substituted luciferins as bioluminescent probes for glutathione S-transferase assays. Chem. Commun., 2006, 4620.
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5. For a recent review on the chemistry of azetidines based on this methodology, see: Couty, F.; Evano, G. Azetidines: new tools for the synthesis of nitrogen heterocycles. Synlett, 2009, 19, 3053.
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7. For similar examples, see: a) Sivaprakasam, M.; Couty, F.; David, O.; Marrot, J.; Sridhar, R.; Srinivas, B.; Rama Rao, K. A Straightforward synthesis of enantiopure bicyclic azetidines. Eur. J. Org. Chem. 2007, 5734.
8. b) Sivaprakasam, M.; Couty, F.; Evano, G.; Sridhar, R.; Srinivas, B.; Rama Rao, K. A straighforward synthesis of 3-substituted azetidinic amino acids. Arkivoc 2007, X, 71.
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