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Volumn 2007, Issue 10, 2007, Pages 71-93

A straighforward synthesis of 3-substituted azetidinic amino acids

Author keywords

Amino acids; Amino alcohols; Azetidines

Indexed keywords


EID: 33846220032     PISSN: 1551-7012     EISSN: 14246376     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (36)
  • 9
    • 0000218162 scopus 로고
    • Fowden, L. Nature 1955, 176, 347.
    • (1955) Nature , vol.176 , pp. 347
    • Fowden, L.1
  • 30
    • 85069131488 scopus 로고    scopus 로고
    • (2S,3R)-O-benzyl threoninol was prepared from (2S,3R) N-Boc-O-benzyl threonine13 throug a two-step sequence involving N-Boc deprotection (TFA in DCM, rt, 0.5h, 95%) followed by LAH reduction (LiAlH4, THF, reflux, 3h, 36%).
    • (2S,3R)-O-benzyl threoninol was prepared from (2S,3R) N-Boc-O-benzyl threonine13 throug a two-step sequence involving N-Boc deprotection (TFA in DCM, rt, 0.5h, 95%) followed by LAH reduction (LiAlH4, THF, reflux, 3h, 36%).
  • 36
    • 0000711725 scopus 로고    scopus 로고
    • Shiosaki, K.; Rapoport, H. J. Org. Chem. 1985, 50, 1229. The signal of the H-2 proton appears more deshielded in the trans isomer (3.4-3.5 ppm) than in the cis isomer (3.15-3.20 ppm).
    • Shiosaki, K.; Rapoport, H. J. Org. Chem. 1985, 50, 1229. The signal of the H-2 proton appears more deshielded in the trans isomer (3.4-3.5 ppm) than in the cis isomer (3.15-3.20 ppm).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.