Assessment of physiological parameters within glioblastomas in awake patients: A prospective clinical study

British Journal of Neurosurgery

Volumn 24, Issue 4, 2010, Pages 447-453

  Whittle, Ian R ^a   Stavrinos, Neo ^a   Akil, Hazem ^a   Yau, Yh ^a   Lewis, Stephanie C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

glioblastoma; hypoxia pathophysiology; monitoring; oxygen

Indexed keywords

BICARBONATE; CARBON DIOXIDE; OXYGEN;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; GLIOBLASTOMA; HUMAN; OXYGEN TISSUE LEVEL; PH; PRIORITY JOURNAL; TEMPERATURE; WAKEFULNESS;

ANOXIA; BRAIN NEOPLASMS; CEREBRAL CORTEX; CONSCIOUS SEDATION; FEMALE; GLIOBLASTOMA; HUMANS; MALE; MONITORING, INTRAOPERATIVE; OXYGEN; PROSPECTIVE STUDIES; RECOVERY OF FUNCTION; TREATMENT OUTCOME;

EID: 77955965435     PISSN: 02688697     EISSN: 1360046X     Source Type: Journal    
DOI: 10.3109/02688691003746290     Document Type: Article

References (22)

1. Brat DJ, Castellano-Sanchez AA, et al. Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Res 2004 Feb 1;64(3):920-927.
2. Evans SM, Judy KD, Dunphy I, et al. Hypoxia is important in the biology and aggression of human glial brain tumours. Clin Cancer Res 2004;10:8177-8184.
3. Rong Y, Durden DL, Van Meir EG, Brat DJ. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. J Neuropathol Exp Neurol 2006;65(6):529-539.
4. Liang Y, Diehn M, Watson N, Bollen AW, Aldape KD, Nicholas MK, Lamborn KR, Berger MS, Botstein D, Brown PO, Israel MA. Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. Proc Natl Acad Sci 2005;102:5814-5819.
5. Collingridge DR, Piepmeier JM, Rockwell S, Knisely JPS. Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue. Radiother Oncol 1999:53:127-131.
6. Cruikshank GS, Rampling R. Peri-tumoural hypoxia in human brain: preoperative measurement of the tissue oxygen tension around malignant brain tumours. Acta Neurochir Suppl (Wien) 1994;60:375-377.
7. Helminger G, Yuan F, Dellian M, Jain RK. Interstitial pH and PO2 gradients in solid tumours in vivo: High-resolution measurements reveal a lack of correlation. Nat Med 1997; 3;177-182.
8. Evans SM, Judy KD, Dunphy I, et al. Comparative measurements of hypoxia in human brain tumours using needle electrodes and EF5 binding. Cancer Res 2004;64:1886-1892.
9. Parliament MB, Franko AJ, Allalunis A, et al. Anomalous patterns of nitroimidazole binding adjacent to necrosis in human glioma xenografts: possible role of decreased oxygen consumption. Br J Cancer 1997;75:311-318.
10. Valk PE, Mathis CA, Prados MD, Gilbert JC, Budinger TF. Hypoxia in human gliomas: demonstration by PET with Fluormisonidazole. J Nucl Med 1992;33(12):2133-2137.
11. Groshar D, McEwan AJ, Parliament MB, et al. Imaging tumor hypoxia and tumor perfusion. J Nucl Med 1993; 34(6):885-888.
12. Beppu T, Kamada K, Yoshida Y, Arai H, Ogasawara K, Ogawa A. Change of oxygen pressure in glioblastoma tissue under various conditions. J Neurooncol 2002;58(1):47-52.
13. Dings J, Meixensberger J, Jager A, Roosen K. Clinical experience with 118 brain tissue oxygen partial pressure catheter probes. Neurosurgery 1998;43(5):1082-1095.
14. Zauner A, Daugherty WP, Bullock MR, Warner DS. Brain oxygenation and energy metabolism: part 1-Biological function and pathophysiology. Neurosurgery 2002;51(2):289-302.
15. Zauner A, Doppenberg E, Woodward JJ, et al.Multiparametric continuous monitoring of brain metabolism and substrate delivery in neurosurgical patients. Neurol Res 1997;19:265-273.
16. Pennings FA, Bouma GJ, Kedaria M, et al. Intraoperative monitoring of brain tissue oxygen and carbon dioxide pressures reveals low oxygenation in peritumoral brain edema. J Neurosurg Anesthesiol 2003;15(1):1-5.
17. Imberti R, Bellinzona G, Langer M. Cerebral tissue PO2 and SjvO2 changes during moderate hyperventilation in patients with severe traumatic brain injury. J Neurosurg 2002;96(1):97-102.
18. Jaeger M, Soehle M, Meixenberger J. Brain tissue oxygen (PtiO2): a comparison of two monitoring devices. Acta Neurochir Suppl 2005;95:79-81.
19. Rampling R, Cruickshank G, Lewis AD, Fitzsimmons SA, Workman P. Direct measurement of pO2 distribution and bioreductive enzymes in human malignant brain tumors. Int J Radiat Oncol Biol Phys 1994;15(29-3):427-431.
20. Clavo B, Robaina F, Morera J, et al. Increase of brain tumor oxygenation during cervical cord stimulation. J Neurosurg Spine 1 2002;96:94-100.
21. Kayama T, Yoshimoto T, Fujimoto S, Sakurai Y. Intratumoral oxygen pressure in malignant brain tumor. J Neurosurg 1991;74:55-59.
22. Anderson E, Grant R, Lewis SC, Whittle IR. Randomized Phase III controlled trials of therapy in malignant glioma: Where are we after 40 years? Br J Neurosurg 2008;22:339-349.