The individual and combined metabolite profiles (metabolomics) of dibutylphthalate and di(2-ethylhexyl)phthalate following a 28-day dietary exposure in rats

Toxicology Letters

Volumn 198, Issue 2, 2010, Pages 159-170

  van Ravenzwaay, B ^a   Coelho Palermo Cunha, G ^a   Strauss, V ^a   Wiemer, J ^b   Leibold, E ^a   Kamp, H ^a   Walk, T ^b   Mellert, W ^a   Looser, R ^b   Prokoudine, A ^b   Fabian, E ^a   Krennrich, G ^a   Herold, M ^b  

^a BASF SE   (Germany)

^b Metanomics GmbH   (Germany)

Author keywords

Combination toxicity; Di(2 ethylhexyl)phthalate; Dibutylphthalate; Metabolite profiling; Metabolomics; Mode of action

Indexed keywords

CYANIDE; PALMITOYL COENZYME A; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PHTHALIC ACID DIBUTYL ESTER;

ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIET; ENZYME METABOLISM; FEMALE; MALE; METABOLOMICS; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; RAT; SEX RATIO;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIBUTYL PHTHALATE; DIETHYLHEXYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENVIRONMENTAL POLLUTANTS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LIVER; MALE; METABOLOME; METABOLOMICS; ORGAN SIZE; RATS; RATS, WISTAR; SEX FACTORS; TANDEM MASS SPECTROMETRY; TOXICITY TESTS, CHRONIC;

RATTUS; RATTUS NORVEGICUS;

EID: 77955927758     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.06.009     Document Type: Article

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