Development of a Higee bioreactor (HBR) for production of polyhydroxyalkanoate: Hydrodynamics, gas-liquid mass transfer and fermentation studies

Chemical Engineering and Processing: Process Intensification

Volumn 49, Issue 7, 2010, Pages 748-758

  Boodhoo, Kamelia V K ^a   Cartwright, Craig D ^a   Vicevic, Marija ^a   Prieto, Maria A ^b   Tortajada, Marta ^c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Biopolymers; Bioprocess intensification; Bubble size; Higee bioreactor; Oxygen transfer; P. putida fermentation; PHA; Rotating packed bed

Indexed keywords

BIOPROCESS INTENSIFICATION; BUBBLE SIZE; HIGEE BIOREACTOR; OXYGEN TRANSFER; P. PUTIDA FERMENTATION; PHA; ROTATING PACKED BED;

BIOCONVERSION; BIOMOLECULES; BIOPOLYMERS; BIOREACTORS; FLUID DYNAMICS; HYDRODYNAMICS; LIQUIDS; MASS TRANSFER; OXYGEN; PACKED BEDS; ROTATION; VISUALIZATION;

FERMENTATION;

EID: 77955926561     PISSN: 02552701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cep.2010.01.005     Document Type: Article

References (39)

1. Tian P.-Y., et al. Biosynthesis of polyhydroxyalkanoates: current research and development. Afr. J. Biotechnol. 2009, 8(5):709-714.
2. Snell K.D., Peoples O.P. PHA bioplastic: a value-added coproduct for biomass biorefineries. Biofuels Bioprod. Bioref. 2009, 3:456-467.
3. Sun Z., Ramsay J.A., Guay M., Ramsay B.A. Fermentation process development for the production of medium-chain-length poly-3-hyroxyalkanoates. Appl. Microbiol. Biotechnol. 2007, 75:475-485.
4. Akay G., Erhan E., Keskinler B. Bioprocess intensification in flow-through monolithic microbioreactors with immobilized bacteria. Biotechnol. Bioeng. 2005, 90(2):180-190.
5. Guo Y., Lou F., Peng Z.-Y., Yuan Z.-Y. Kinetics of growth and alphaamylase production of immobilised Bacillus subtilis in an air-lift bioreactor. Biotechnol. Bioeng. 1990, 35:99-102.
6. Chisti Y., Moo-Young M. Bioprocess intensification through bioreactor engineering. Trans. IChemE 1996, 74(A):575-583.
7. Nagya E., Feczkóa T., Koroknaia B. Enhancement of oxygen mass transfer rate in the presence of nanosized particles. Chem. Eng. Sci. 2007, 62:7391-7398.
8. Quijano G., et al. Oxygen transfer in three-phase airlift and stirred tank reactors using silicone oil as transfer vector. Process Biochem. 2009, 44:619-624.
9. Knoll A., et al. High cell density cultivation of recombinant yeasts and bacteria under non-pressurized and pressurized conditions in stirred tank bioreactors. J. Biotechnol. 2007, 132:167-179.
10. Flores-Cotera L.B., Garci{dotless}a-Salas S. Gas holdup, foaming and oxygen transfer in a jet loop bioreactor with artificial foaming media and yeast culture. J. Biotechnol. 2005, 116:387-396.
11. Behr A., Becker M., Dostal J. Bubble-size distributions and interfacial areas in a jet loop reactor for multiphase catalysis. Chem. Eng. Sci. 2009, 64:2934-2940.
12. Fadavi A., Chisti Y. Gas-liquid mass transfer in a novel forced circulation loop reactor. Chem. Eng. J. 2005, 112:73-80.
13. Fadavi A., Chisti Y. Gas holdup and mixing characteristics of a novel forced circulation loop reactor. Chem. Eng. J. 2007, 131:105-111.
14. Chisti Y., Jauregui-Haza U.J. Oxygen transfer and mixing in mechanically agitated airlift bioreactors. Biochem. Eng. J. 2002, 10:143-153.
15. Pollard M.D.J., Ison A.P., Ayazi Shamlou P., Lilly M.D. Influence of a propeller on Saccharomyces cerevisiae fermentations in a pilot scale airlift bioreactor. Bioprocess Eng. 1997, 16:273-281.
16. 3 catalyst. J. Appl. Polym. Sci. 2006, 101:8-19.
17. Vicevic M., et al. Catalytic isomerisation of α-pinene oxide to campholenic aldehyde using silica-supported zinc triflate catalysts. II. Performance of immobilised catalysts in a continuous spinning disc reactor. Chem. Eng. J. 2007, 133:43-47.
18. Burns J.R., Ramshaw C. Process intensification: visual study of liquid maldistribution in rotating packed beds. Chem. Eng. Sci. 1996, 51(8):1347-1352.
19. Lin C.C., et al. Removal of carbon dioxide by absorption in a rotating packed bed. Ind. Eng. Chem. Res. 2003, 42:2381-2386.
20. Kumar M.P., Rao D.P. Studies on a high-gravity gas-liquid contactor. Ind. Eng. Chem. Res. 1990, 29:917.
21. Peel J.A.R., Howarth C., Ramshaw C. Process intensification: Higee seawater de-aeration. Trans. IChemE 1998, 76(A):585-593.
22. Munjal S., Dudukovic M.P., Ramachandran P.A. Mass-transfer in rotating packed beds. II. Experimental results and comparison with theory and gravity flow. Chem. Eng. Sci. 1989, 44(10):2257-2268.
23. Boodhoo K.V.K., et al. Intensification of gas-liquid mass transfer using a rotating bed of porous packings for application to an E. coli batch fermentation. Chem. Eng. J. 2008, 135:141-150.
24. Hoffmeister H.P.A. Rotating bed bioreactors: a novel way to natural proteins by tissue-like cultivation of mammalian cells. Cell Technology for Cell Products 2007, 799-801. Springer. R. Smith (Ed.).
25. Yang S.-T., et al. Xanthan gum fermentation by Xanthomonas campestris immobilised in a novel centrifugal fibrous-bed bioreactor. Biotechnol. Prog. 1996, 12:630-637.
26. M. Jassim, Process intensification: absorption and desorption of carbon dioxide from monoethanolamine solutions using Higee technology, Ph.D. Thesis, Newcastle University, 2002.
27. http://water.usgs.gov/owq/FieldManual/Chapter6/6.2.4.pdf.
28. Sherwood T.K., et al. Flooding velocities in packed beds. Ind. Eng. Chem. Res. 1938, 30:765-769.
29. J.A.R. Peel, Mass transfer and hydrodynamics in a gas-liquid centrifugal field de-oxygenator, Ph.D. Thesis, Newcastle University, 1995.
30. Calderbank P., Jones S. Trans. IChemE 1961, 39:363.
31. Davidson J., Schuler B. Trans. IChemE 1960, 38:335-341.
32. Kelleher T., Fair J.R. Distillation studies in a high-gravity contactor. Ind. Eng. Chem. Res. 1996, 35:4646-4655.
33. Liley P., et al. Physical and chemical data. Perry's Chemical Engineers' Handbook 1984, 3-103. 6th edition. R.H. Perry, D. Green (Eds.).
34. Tortajada M., et al. Pilot scale mcl-polyalkanoate production and purification from Pseudomonas putida KT2442. Proceedings of the 1st Annual Bioproduction Meeting 2007.
35. Young K.D. The selective value of bacterial shape. Microbiol. Mol. Biol. Rev. 2006, 70(3):660-703.
36. James G.A., Korber D.R., Caldwell D.E., Costerton J.W. Digital image analysis of growth and starvation responses of a surface colonizing Acinetobacter sp. J. Bacteriol. 1995, 177:907-915.
37. S. J. Bacteriol. 1991, 173:4474-4481.
38. Goodfellow M. Genus Rhodococcus Zopf 1891. Bergey's Manual of Systematic Bacteriology 1989, vol. 4:2362-2371. Williams and Wilkins, Baltimore, MD.
39. Madigan M.T., et al. Brock: Biology of Microorganisms 2009, Pearson Benjamin Cummings. 12th edition.