메뉴 건너뛰기




Volumn 74, Issue 5, 1996, Pages 575-583

Bioprocess intensification through bioreactor engineering

Author keywords

Animal cell culture; Bioprocess intensification; Bioreactors; Fermentation technology

Indexed keywords

ANIMAL CELL CULTURE; BIOCATALYSTS; BIOREACTORS; FERMENTATION; HEAT TRANSFER; MASS TRANSFER; PROCESS ENGINEERING; SYNTHESIS (CHEMICAL);

EID: 0030195477     PISSN: 02638762     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (53)

References (61)
  • 1
    • 0027239129 scopus 로고
    • Fermentation of cellulosic materials to mycoprotein foods
    • Moo-Young, M., Chisti, Y. and Vlach, D., 1994, Fermentation of cellulosic materials to mycoprotein foods, Biotechnol Adv, 11: 469-479.
    • (1994) Biotechnol Adv , vol.11 , pp. 469-479
    • Moo-Young, M.1    Chisti, Y.2    Vlach, D.3
  • 2
    • 0002712346 scopus 로고
    • Fermentation technology, bioprocessing, scale-up and manufacture
    • Moses, V. and Cape, R. E., editors, (Harwood Academic Publishers, New York)
    • Chisti, Y. and Moo-Young, M., 1991, Fermentation technology, bioprocessing, scale-up and manufacture, in Biotechnology: The Science and the Business, Moses, V. and Cape, R. E., editors, (Harwood Academic Publishers, New York), pp. 167-209.
    • (1991) Biotechnology: The Science and the Business , pp. 167-209
    • Chisti, Y.1    Moo-Young, M.2
  • 4
    • 0022702156 scopus 로고
    • Disruption of microbial cells for intracellular products
    • Chisti, Y. and Moo-Young, M., 1986, Disruption of microbial cells for intracellular products, Enzyme Microb Technol, 8: 194-204.
    • (1986) Enzyme Microb Technol , vol.8 , pp. 194-204
    • Chisti, Y.1    Moo-Young, M.2
  • 5
    • 0002786653 scopus 로고
    • Build better industrial bioreactors
    • Chisti, Y., 1992, Build better industrial bioreactors, Chem Eng Progress, 88(1): 55-58.
    • (1992) Chem Eng Progress , vol.88 , Issue.1 , pp. 55-58
    • Chisti, Y.1
  • 6
    • 0026928216 scopus 로고
    • Assure bioreactor sterility
    • Chisti, Y., 1992, Assure bioreactor sterility, Chem Eng Prog, 88(9): 80-85.
    • (1992) Chem Eng Prog , vol.88 , Issue.9 , pp. 80-85
    • Chisti, Y.1
  • 7
    • 0028102163 scopus 로고
    • Clean-in-place systems for industrial bioreactors: Design, validation and operation
    • Chisti, Y. and Moo-Young, M., 1994, Clean-in-place systems for industrial bioreactors: Design, validation and operation, J Ind Microbiol, 13: 201-207.
    • (1994) J Ind Microbiol , vol.13 , pp. 201-207
    • Chisti, Y.1    Moo-Young, M.2
  • 8
    • 0027040632 scopus 로고
    • Fluid-mechanical damage of freely-suspended animal cells in agitated bioreactors: Effects of dextran, derivatized celluloses and polyvinyl alcohol
    • Michaels, J. D., Kunas, K. T. and Papoutsakis, E. T., 1992, Fluid-mechanical damage of freely-suspended animal cells in agitated bioreactors: Effects of dextran, derivatized celluloses and polyvinyl alcohol, Chem Eng Commun, 118: 341-360.
    • (1992) Chem Eng Commun , vol.118 , pp. 341-360
    • Michaels, J.D.1    Kunas, K.T.2    Papoutsakis, E.T.3
  • 9
    • 0028846541 scopus 로고
    • Effects of the hydrodynamic environment and shear protectants on survival of erythrocytes in suspension
    • Zhang, Z., Chisti, Y. and Moo-Young, M., 1995, Effects of the hydrodynamic environment and shear protectants on survival of erythrocytes in suspension, J Biotechnol, 43: 33-40.
    • (1995) J Biotechnol , vol.43 , pp. 33-40
    • Zhang, Z.1    Chisti, Y.2    Moo-Young, M.3
  • 10
    • 0028110779 scopus 로고
    • High density cell culture by membrane-based cell recycle
    • Chang, H. N., Yoo, I.-K. and Kim, B. S., 1994, High density cell culture by membrane-based cell recycle, Biotechnol Adv, 12: 467-487.
    • (1994) Biotechnol Adv , vol.12 , pp. 467-487
    • Chang, H.N.1    Yoo, I.-K.2    Kim, B.S.3
  • 11
    • 0001076612 scopus 로고
    • Separation techniques in industrial bioprocessing
    • Chisti, Y. and Moo-Young, M., 1994, Separation techniques in industrial bioprocessing, IChemE Symp Ser, 137: 135-146.
    • (1994) IChemE Symp Ser , vol.137 , pp. 135-146
    • Chisti, Y.1    Moo-Young, M.2
  • 12
    • 0025385745 scopus 로고
    • Mass transfer in external-loop airlift bioreactors using static mixers
    • Chisti, Y., Kasper, M. and Moo-Young, M., 1990, Mass transfer in external-loop airlift bioreactors using static mixers, Can J Chem Eng, 68: 45-50.
    • (1990) Can J Chem Eng , vol.68 , pp. 45-50
    • Chisti, Y.1    Kasper, M.2    Moo-Young, M.3
  • 13
    • 0027416179 scopus 로고
    • Cephalosporin C production by a highly productive Cephalosporium acremonium strain in an airlift tower loop reactor with static mixers
    • Zhou, W., Holzhaur-Rieger, K. and Schügerl, K., 1993, Cephalosporin C production by a highly productive Cephalosporium acremonium strain in an airlift tower loop reactor with static mixers, J Biotechnol, 28: 165-177.
    • (1993) J Biotechnol , vol.28 , pp. 165-177
    • Zhou, W.1    Holzhaur-Rieger, K.2    Schügerl, K.3
  • 15
    • 0028457004 scopus 로고
    • Bioreactor applications in waste treatment
    • Moo-Young, M. and Chisti, Y., 1994, Bioreactor applications in waste treatment, Res Cons Recycl, 11: 13-24.
    • (1994) Res Cons Recycl , vol.11 , pp. 13-24
    • Moo-Young, M.1    Chisti, Y.2
  • 16
    • 0018948797 scopus 로고
    • On the mechanism of heat transfer in bubble column reactors
    • Deckwer, W.-D., 1980, On the mechanism of heat transfer in bubble column reactors, Chem Eng Sci, 35: 1341-1346.
    • (1980) Chem Eng Sci , vol.35 , pp. 1341-1346
    • Deckwer, W.-D.1
  • 18
    • 3042966329 scopus 로고
    • The application of airlift reactors for immobilized enzyme reactions
    • Furusaki, S., Endo, I. and Matsuno, R., editors, (Springer-Verlag, Tokyo)
    • Cheng, C.-M., Lu, W. J., Own, K. S. and Hwang, S.-J., 1992, The application of airlift reactors for immobilized enzyme reactions, in Proc Asia-Pacific Biochemical Engineering Conf 1992, Furusaki, S., Endo, I. and Matsuno, R., editors, (Springer-Verlag, Tokyo), pp. 437-440.
    • (1992) Proc Asia-Pacific Biochemical Engineering Conf 1992 , pp. 437-440
    • Cheng, C.-M.1    Lu, W.J.2    Own, K.S.3    Hwang, S.-J.4
  • 19
  • 20
    • 0028987959 scopus 로고
    • Hydrodynamic behaviour of animal cell microcarrier suspensions in split-cylinder airlift bioreactors
    • Ganzeveld, K. J., Chisti, Y. and Moo-Young, M., 1995, Hydrodynamic behaviour of animal cell microcarrier suspensions in split-cylinder airlift bioreactors, Bioproc Eng, 12: 239-247.
    • (1995) Bioproc Eng , vol.12 , pp. 239-247
    • Ganzeveld, K.J.1    Chisti, Y.2    Moo-Young, M.3
  • 21
    • 0025580001 scopus 로고
    • Microcarrier culture systems
    • Lubiniecki, A.S., editor, (Marcel Dekker, New York)
    • Reuveny, S., 1990, Microcarrier culture systems, in Large-Scale Mammalian Cell Culture Technology, Lubiniecki, A.S., editor, (Marcel Dekker, New York), pp. 271-341.
    • (1990) Large-Scale Mammalian Cell Culture Technology , pp. 271-341
    • Reuveny, S.1
  • 22
    • 3042967859 scopus 로고
    • Airlift bioreactors for treatment of hydrocarbon contaminated wastes
    • Teo, W. K., Yap, M. G. S. and Oh, S. K. W., editors, (University of Singapore, Singapore)
    • Chisti, Y. and Moo-Young, M., 1994, Airlift bioreactors for treatment of hydrocarbon contaminated wastes, in Better Living Through Biochemical Engineering, Teo, W. K., Yap, M. G. S. and Oh, S. K. W., editors, (University of Singapore, Singapore), pp. 771-776.
    • (1994) Better Living Through Biochemical Engineering , pp. 771-776
    • Chisti, Y.1    Moo-Young, M.2
  • 23
    • 0026024814 scopus 로고
    • Sand and activated carbon as biofilm carriers for microbial degradation of phenols and nitrogen-containing aromatic compounds
    • Koch, B., Ostermann, M., Höke, H. and Hempel, D.-C., 1991, Sand and activated carbon as biofilm carriers for microbial degradation of phenols and nitrogen-containing aromatic compounds, Wat Res, 25: 1-8.
    • (1991) Wat Res , vol.25 , pp. 1-8
    • Koch, B.1    Ostermann, M.2    Höke, H.3    Hempel, D.-C.4
  • 24
    • 85007994925 scopus 로고
    • Mass transfer coefficients for suspended particles in agitated vessels and bubble columns
    • Sano, Y., Yamaguchi, N. and Adachi, T., 1974, Mass transfer coefficients for suspended particles in agitated vessels and bubble columns, J Chem Eng Jpn, 7: 255-261.
    • (1974) J Chem Eng Jpn , vol.7 , pp. 255-261
    • Sano, Y.1    Yamaguchi, N.2    Adachi, T.3
  • 25
    • 0002786412 scopus 로고
    • Multiphase hydrodynamics and solid-liquid mass transport in an external-loop airlift reactor - A comparative study
    • Mao, H. H., Chisti, Y. and Moo-Young, M., 1992, Multiphase hydrodynamics and solid-liquid mass transport in an external-loop airlift reactor - A comparative study, Chem Eng Commun, 113: 1-13.
    • (1992) Chem Eng Commun , vol.113 , pp. 1-13
    • Mao, H.H.1    Chisti, Y.2    Moo-Young, M.3
  • 26
    • 0026918491 scopus 로고
    • The effect of static mixer on mass transfer in draft tube bubble column and in external loop column
    • Goto, S. and Gaspillo, P. D., 1992, The effect of static mixer on mass transfer in draft tube bubble column and in external loop column, Chem Eng Sci, 47: 3533-3539.
    • (1992) Chem Eng Sci , vol.47 , pp. 3533-3539
    • Goto, S.1    Gaspillo, P.D.2
  • 27
    • 0026923030 scopus 로고
    • Prediction of minimum gas velocity in suspended bubble columns and airlift reactors
    • Immich, M. and Onken, U., 1992, Prediction of minimum gas velocity in suspended bubble columns and airlift reactors, Chem Eng Sci, 47: 3379-3386.
    • (1992) Chem Eng Sci , vol.47 , pp. 3379-3386
    • Immich, M.1    Onken, U.2
  • 28
    • 0010265709 scopus 로고
    • Mass transfer and reaction in bubble column slurry reactor with draft tube
    • Goto, S., Matsumoto, Y. and Gaspillo, P., 1989, Mass transfer and reaction in bubble column slurry reactor with draft tube, Chem Eng Commun, 85: 181-191.
    • (1989) Chem Eng Commun , vol.85 , pp. 181-191
    • Goto, S.1    Matsumoto, Y.2    Gaspillo, P.3
  • 29
    • 0026241324 scopus 로고
    • Mass transfer in bubble slurry column with static mixer in draft tube
    • Gaspillo, P. D. and Goto, S., 1991, Mass transfer in bubble slurry column with static mixer in draft tube, J Chem Eng Jpn, 24: 680-682.
    • (1991) J Chem Eng Jpn , vol.24 , pp. 680-682
    • Gaspillo, P.D.1    Goto, S.2
  • 30
    • 0027610585 scopus 로고
    • Improve the performance of airlift reactors
    • Chisti, Y. and Moo-Young, M., 1993, Improve the performance of airlift reactors, Chem Eng Prog, 89(6): 38-45.
    • (1993) Chem Eng Prog , vol.89 , Issue.6 , pp. 38-45
    • Chisti, Y.1    Moo-Young, M.2
  • 31
    • 0025700058 scopus 로고
    • Kinetics of growth and α-amylase production of immobilized Bacillus subtilisin an airlift bioreactor
    • Guo, Y., Lou, F., Peng, Z.-Y., Yuan, Z.-Y. and Korus, R. A., 1990, Kinetics of growth and α-amylase production of immobilized Bacillus subtilisin an airlift bioreactor, Biotechnol Bioeng, 35:99-102.
    • (1990) Biotechnol Bioeng , vol.35 , pp. 99-102
    • Guo, Y.1    Lou, F.2    Peng, Z.-Y.3    Yuan, Z.-Y.4    Korus, R.A.5
  • 32
    • 0027660348 scopus 로고
    • Airlift bioreactors with packed beds of immobilized biocatalysts: Theoretical evaluation of liquid circulation performance
    • Chisti, Y. and Moo-Young, M., 1993, Airlift bioreactors with packed beds of immobilized biocatalysts: Theoretical evaluation of liquid circulation performance, Trans IChemE, 71C: 209-214.
    • (1993) Trans IChemE , vol.71 C , pp. 209-214
    • Chisti, Y.1    Moo-Young, M.2
  • 33
    • 0028446786 scopus 로고
    • Anchorage dependent animal cell culture in packed beds with airlift driven liquid circulation: A theoretical analysis of oxygen transfer and comparison with stirred tank microcarrier culture system
    • Chisti, Y. and Moo-Young, M., 1994, Anchorage dependent animal cell culture in packed beds with airlift driven liquid circulation: A theoretical analysis of oxygen transfer and comparison with stirred tank microcarrier culture system, Trans IChemE, 72C: 91-94.
    • (1994) Trans IChemE , vol.72 C , pp. 91-94
    • Chisti, Y.1    Moo-Young, M.2
  • 34
    • 0017120530 scopus 로고
    • The production of foot-and-mouth disease virus from BHK 21 C 13 cells grown on the surface of glass spheres
    • Spier, R. E. and Whiteside, J. P., 1976, The production of foot-and-mouth disease virus from BHK 21 C 13 cells grown on the surface of glass spheres, Biotechnol Bioeng, 18: 649-657.
    • (1976) Biotechnol Bioeng , vol.18 , pp. 649-657
    • Spier, R.E.1    Whiteside, J.P.2
  • 35
    • 0026416662 scopus 로고
    • A fiber-bed bioreactor for anchorage-dependent animal cell cultures: Part I. Bioreactor design and operation
    • Chiou, T.-W., Murakami, S., Wang, D. I. C. and Wu, W.-T., 1991, A fiber-bed bioreactor for anchorage-dependent animal cell cultures: Part I. Bioreactor design and operation, Biotechnol Bioeng, 37: 755-761.
    • (1991) Biotechnol Bioeng , vol.37 , pp. 755-761
    • Chiou, T.-W.1    Murakami, S.2    Wang, D.I.C.3    Wu, W.-T.4
  • 36
    • 0026707311 scopus 로고
    • Fermentative conversion of cellulosic substrates to microbial protein by Neurospora sitophila
    • Moo-Young, M., Chisti, Y. and Vlach, D., 1992, Fermentative conversion of cellulosic substrates to microbial protein by Neurospora sitophila, Biotechnol Lett, 14: 863-868.
    • (1992) Biotechnol Lett , vol.14 , pp. 863-868
    • Moo-Young, M.1    Chisti, Y.2    Vlach, D.3
  • 38
    • 0006797621 scopus 로고
    • Studies on the performance of bioreactors used for the fermentation process with highly viscous broth
    • Furusaki, S., Endo, I. and Matsuno, R., editors, (Springer-Verlag, Tokyo)
    • Cai, Z., Yang, S., Kang, R., Sun, X., Liu, W., Li, G. and Wang, Y., 1992, Studies on the performance of bioreactors used for the fermentation process with highly viscous broth, in Proc Asia-Pacific Biochemical Engineering Conf 7992, Furusaki, S., Endo, I. and Matsuno, R., editors, (Springer-Verlag, Tokyo), pp. 429-432.
    • (1992) Proc Asia-Pacific Biochemical Engineering Conf 7992 , pp. 429-432
    • Cai, Z.1    Yang, S.2    Kang, R.3    Sun, X.4    Liu, W.5    Li, G.6    Wang, Y.7
  • 39
    • 0027111928 scopus 로고
    • Xanthan production in bubble column and air-lift reactors
    • Suh, I.-S., Schumpe, A. and Deckwer, W.-D., 1992, Xanthan production in bubble column and air-lift reactors, Biotechnol Bioeng, 39: 85-94.
    • (1992) Biotechnol Bioeng , vol.39 , pp. 85-94
    • Suh, I.-S.1    Schumpe, A.2    Deckwer, W.-D.3
  • 40
    • 0026571674 scopus 로고
    • Exopolysaccharide production by Acremonium persicinum in stirred-tank and air-lift fermentors
    • Stasinopoulos, S. J. and Seviour, R. J., 1992, Exopolysaccharide production by Acremonium persicinum in stirred-tank and air-lift fermentors, Appl Microbiol Biotechnol, 36: 465-468.
    • (1992) Appl Microbiol Biotechnol , vol.36 , pp. 465-468
    • Stasinopoulos, S.J.1    Seviour, R.J.2
  • 41
    • 0000893741 scopus 로고
    • Considerations for designing bioreactors for shear-sensitive culture
    • Moo-Young, M. and Chisti, Y., 1988, Considerations for designing bioreactors for shear-sensitive culture, Biotechnology, 6(11): 1291-1296.
    • (1988) Biotechnology , vol.6 , Issue.11 , pp. 1291-1296
    • Moo-Young, M.1    Chisti, Y.2
  • 42
    • 0022730202 scopus 로고
    • Large-scale cell culture in biotechnology
    • Arathoon, W. R. and Birch, J. R., 1986, Large-scale cell culture in biotechnology, Science, 232: 1390-1395.
    • (1986) Science , vol.232 , pp. 1390-1395
    • Arathoon, W.R.1    Birch, J.R.2
  • 44
    • 0023887786 scopus 로고
    • Large-scale production of proteins from mammalian cells
    • Rhodes, M. and Birch, J., 1988, Large-scale production of proteins from mammalian cells, Biotechnology, 6: 518-523.
    • (1988) Biotechnology , vol.6 , pp. 518-523
    • Rhodes, M.1    Birch, J.2
  • 45
    • 0024242299 scopus 로고
    • Large-scale insect cell-culture for recombinant protein production
    • Maiorella, B., Inlow, D., Shauger, A. and Harano, D., 1988, Large-scale insect cell-culture for recombinant protein production, Biotechnology, 6: 1406-1410.
    • (1988) Biotechnology , vol.6 , pp. 1406-1410
    • Maiorella, B.1    Inlow, D.2    Shauger, A.3    Harano, D.4
  • 46
    • 0004651995 scopus 로고
    • Preliminary investigation on anchorage-dependent cell culture by air-lift suspending micro-carriers
    • Teo, W. K., Yap, M. G. S. and Oh, S. K. W., editors, (University of Singapore, Singapore)
    • Dai, X., Ouyang, F. and Qi, Y., 1994, Preliminary investigation on anchorage-dependent cell culture by air-lift suspending micro-carriers, in Better Living Through Biochemical Engineering, Teo, W. K., Yap, M. G. S. and Oh, S. K. W., editors, (University of Singapore, Singapore), pp. 408-410.
    • (1994) Better Living Through Biochemical Engineering , pp. 408-410
    • Dai, X.1    Ouyang, F.2    Qi, Y.3
  • 47
    • 0026478845 scopus 로고
    • Flow-dependent cytosolic acidification of vascular endothelial cells
    • Ziegelstein, R. C., Cheng, L., Capogrossi, M. C., 1992, Flow-dependent cytosolic acidification of vascular endothelial cells, Science, 258: 656-659.
    • (1992) Science , vol.258 , pp. 656-659
    • Ziegelstein, R.C.1    Cheng, L.2    Capogrossi, M.C.3
  • 48
    • 0026954898 scopus 로고
    • Estimation of disruption of animal cells by laminar shear stress
    • Born, C., Zhang, Z., Al-Rubeai, M. and Thomas, C. R., 1992, Estimation of disruption of animal cells by laminar shear stress, Biotechnol Bioeng, 40: 1004-1010.
    • (1992) Biotechnol Bioeng , vol.40 , pp. 1004-1010
    • Born, C.1    Zhang, Z.2    Al-Rubeai, M.3    Thomas, C.R.4
  • 49
    • 0025513915 scopus 로고
    • The role of the plasm membrane fluidity on the shear sensitivity of hybridomas grown under hydrodynamic stress
    • Ramirez, O. T. and Mutharasan, R., 1990, The role of the plasm membrane fluidity on the shear sensitivity of hybridomas grown under hydrodynamic stress, Biotechnol Bioeng, 36: 911-920.
    • (1990) Biotechnol Bioeng , vol.36 , pp. 911-920
    • Ramirez, O.T.1    Mutharasan, R.2
  • 50
    • 0027651498 scopus 로고
    • A numerical analysis of forces exerted by laminar flow on spreading cells in a parallel plate flow chamber assay
    • Olivier, L. A. and Truskey, G. A., 1993, A numerical analysis of forces exerted by laminar flow on spreading cells in a parallel plate flow chamber assay, Biotechnol Bioeng, 42: 963-973.
    • (1993) Biotechnol Bioeng , vol.42 , pp. 963-973
    • Olivier, L.A.1    Truskey, G.A.2
  • 51
    • 0024821348 scopus 로고
    • On the calculation of shear rate and apparent viscosity in airlift and bubble column bioreactors
    • Chisti, Y. and Moo-Young, M., 1989, On the calculation of shear rate and apparent viscosity in airlift and bubble column bioreactors, Biotechnol Bioeng, 34: 1391-1392.
    • (1989) Biotechnol Bioeng , vol.34 , pp. 1391-1392
    • Chisti, Y.1    Moo-Young, M.2
  • 53
    • 44949280176 scopus 로고
    • Fluid-mechanical damage of animal cells in bioreactors
    • Papoutsakis, E. T., 1992, Fluid-mechanical damage of animal cells in bioreactors, Trends Biotechnol, 9: 427-437.
    • (1992) Trends Biotechnol , vol.9 , pp. 427-437
    • Papoutsakis, E.T.1
  • 54
    • 0023062018 scopus 로고
    • On the evaluation of gas-liquid interfacial effects on hybridoma viability in bubble column bioreactors
    • Handa, A., Emery, A. N. and Spier, R. E., 1987, On the evaluation of gas-liquid interfacial effects on hybridoma viability in bubble column bioreactors, Devel Biol Stand, 66: 241-253.
    • (1987) Devel Biol Stand , vol.66 , pp. 241-253
    • Handa, A.1    Emery, A.N.2    Spier, R.E.3
  • 55
    • 0028329435 scopus 로고
    • Unified modelling framework of cell death due to bubbles in agitated and sparged bioreactors
    • Wang, N. S., Yang, J.-D., Calabrese, R. V. and Chang, K.-C., 1994, Unified modelling framework of cell death due to bubbles in agitated and sparged bioreactors, J Biotechnol, 33: 107-122.
    • (1994) J Biotechnol , vol.33 , pp. 107-122
    • Wang, N.S.1    Yang, J.-D.2    Calabrese, R.V.3    Chang, K.-C.4
  • 56
    • 0026848844 scopus 로고
    • Effect of serum concentration on hybridoma viable cell density and production of monoclonal antibodies in CSTRs and on shear sensitivity in air-lift loop reactors
    • Martens, D. E., de Gooijer, C. D., Beuvery, E. C. and Tramper, J., 1992, Effect of serum concentration on hybridoma viable cell density and production of monoclonal antibodies in CSTRs and on shear sensitivity in air-lift loop reactors, Biotechnol Bioeng, 39: 891-897.
    • (1992) Biotechnol Bioeng , vol.39 , pp. 891-897
    • Martens, D.E.1    De Gooijer, C.D.2    Beuvery, E.C.3    Tramper, J.4
  • 57
    • 0026617103 scopus 로고
    • Effect of low serum concentrations (0%-2.5%) on growth, production, and shear sensitivity of hybridoma cells
    • van der Pol, L., Bakker, W. A. M. and Tramper, J., 1992, Effect of low serum concentrations (0%-2.5%) on growth, production, and shear sensitivity of hybridoma cells, Biotechnol Bioeng, 40: 179-182.
    • (1992) Biotechnol Bioeng , vol.40 , pp. 179-182
    • Pol, L.1    Bakker, W.A.M.2    Tramper, J.3
  • 58
    • 0024654299 scopus 로고
    • Effect of gas-liquid interfaces on the growth of suspended mammalian cells: Mechanisms of cell damage by bubbles
    • Handa-Corrigan, A., Emery, A. N. and Spier, R. E., 1989, Effect of gas-liquid interfaces on the growth of suspended mammalian cells: mechanisms of cell damage by bubbles, Enzyme Microb Technol, 11: 230-235.
    • (1989) Enzyme Microb Technol , vol.11 , pp. 230-235
    • Handa-Corrigan, A.1    Emery, A.N.2    Spier, R.E.3
  • 59
    • 0027527774 scopus 로고
    • Animal cell culture in stirred bioreactors: Observations on scale-up
    • Chisti, Y., 1993, Animal cell culture in stirred bioreactors: Observations on scale-up, Bioproc Eng, 9: 191-196.
    • (1993) Bioproc Eng , vol.9 , pp. 191-196
    • Chisti, Y.1
  • 60
    • 0000376019 scopus 로고
    • Design of reactors for plant cells and organs
    • Doran, P. M., 1993, Design of reactors for plant cells and organs, Adv Biochem Eng Biotechnol, 48: 115-168.
    • (1993) Adv Biochem Eng Biotechnol , vol.48 , pp. 115-168
    • Doran, P.M.1
  • 61
    • 0025633999 scopus 로고
    • Ambruticin S production in air-lift and stirred tank bioreactors
    • Hopf, N. W., Yonsel, S. and Deckwer, W.-D., 1990, Ambruticin S production in air-lift and stirred tank bioreactors, Appl Microbiol Biotechnol, 34: 350-353.
    • (1990) Appl Microbiol Biotechnol , vol.34 , pp. 350-353
    • Hopf, N.W.1    Yonsel, S.2    Deckwer, W.-D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.