Etiology and STI/HIV coinfections among patients with urethral and vaginal discharge syndromes in South Africa

Sexually Transmitted Diseases

Volumn 37, Issue 9, 2010, Pages 566-570

  Mhlongo, Sakhile ^a   Magooa, Precious ^a   Müller, Etienne E ^a   Nel, Noel ^b   Radebe, Frans ^a   Wasserman, Elizabeth ^b   Lewis, David A ^a,c,d  

^a NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

^b STELLENBOSCH UNIVERSITY   (South Africa)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM ANTIBODY; CIPROFLOXACIN; CLOTRIMAZOLE; DOXYCYCLINE; HERPES SIMPLEX VIRUS 2 ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; METRONIDAZOLE; SYPHILIS ANTIBODY; UNCLASSIFIED DRUG; VIRUS ANTIBODY;

ANTIBODY SCREENING; ARTICLE; BACTERIUM DETECTION; CANDIDIASIS; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GONORRHEA; HERPES SIMPLEX; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MALE URETHRAL DISCHARGE; MICROSCOPY; MIXED INFECTION; MULTIPLEX POLYMERASE CHAIN REACTION; MYCOPLASMA GENITALIUM; NEISSERIA GONORRHOEAE; SEROLOGY; SEROPREVALENCE; SEXUALLY TRANSMITTED DISEASE; SINGLE DRUG DOSE; SOUTH AFRICA; SYPHILIS; TRICHOMONAS VAGINALIS; TRICHOMONIASIS; URETHRA DISEASE; VAGINA DISCHARGE; VAGINAL DISCHARGE SYNDROME; VAGINITIS;

FEMALE; GENITAL DISEASES, FEMALE; GENITAL DISEASES, MALE; HIV INFECTIONS; HUMANS; MALE; PREVALENCE; SEXUALLY TRANSMITTED DISEASES; SOUTH AFRICA; SYNDROME; URETHRAL DISEASES; VAGINAL DISCHARGE;

EID: 77955924886     PISSN: 01485717     EISSN: None     Source Type: Journal    
DOI: 10.1097/OLQ.0b013e3181d877b7     Document Type: Article

References (28)

1. Pham-Kanter GB, Steinberg MH, Ballard RC. Sexually transmitted diseases in South Africa. Genitourin Med 1996; 72:160-171.
2. Johnson LF, Coetzee DJ, Dorrington RE. Sentinel surveillance of sexually transmitted infections in South Africa: A review. Sex Transm Infect 2005; 81:287-293.
3. Spence D, Melville C. Vaginal discharge. BMJ 2007; 335:1147-1151.
4. National Department of Health. First line comprehensive management and control of sexually transmitted infections (STIs): protocol for the management of a person with a sexually transmitted infection according to the Essential Drug List. Pretoria, South Africa: National Department of Health, 2008:1-18.
5. World Health Organisation, UNAIDS. Sexually transmitted diseases: policies and principles for prevention and care. Geneva, Switzerland: UNAIDS, 1999.
6. Dallabetta GA, Gerbase AC, Holmes KK. Problems, solutions, and challenges in syndromic management of sexually transmitted diseases. Sex Transm Infect 1998; 74(suppl 1):S1-S11.
7. Djajakusumah T, Sudigdoadi S, Keersmaekers K, et al. Evaluation of syndromic patient management algorithm for urethral discharge. Sex Transm Infect 1998; 74(suppl 1):S29-S33.
8. Lewis DA, Scott L, Slabbert M, et al. Escalation in the relative prevalence of ciprofloxacin-resistant gonorrhoea among men with urethral discharge in two South African cities: Association with HIV seropositivity. Sex Transm Infect 2008; 84:352-355.
9. National Department of Health. Essential Drug List and Standard Treatment Guidelines\Primary Health Care (PHC). 2nd ed. Pretoria, South Africa: National Department of Health, 2003.
10. Nugent RP, Krohn MA, Hillier SL. Reliability of diagnosing bacterial vaginosis is improved by a standardized method of Gram stain interpretation. J Clin Microbiol 1991; 29:297-301.
11. National Department of Health. Report on the national HIV and syphilis prevalence survey, South Africa, 2007. Pretoria, South Africa: National Department of Health, 2008.
12. Gould C, Fick N. Selling sex in Cape Town. Pretoria, South Africa: Institute for Security Studies, 2008.
13. Moodley P, Moodley D, Sturm AW. Ciprofloxacin resistant Neis-seria gonorrhoeae in South Africa. Int J Antimicrob Agents 2004; 24:192-193.
14. Adams E, Charlett A, Edmunds W, et al. Chlamydia trachomatis in the United Kingdom: A systematic review and analysis of prevalence studies. Sex Transm Infect 2004; 80:354-362.
15. Rietmeijer C, Hopkins E, Geisler W, et al. Chlamydia trachoma-tis positivity rates among men tested in selected venues in the United States: A review of the recent literature. Sex Transm Dis 2008; 35(suppl 1):S8-S18.
16. Walsh C, Anderson L, Irwin K. The silent epidemic of Chlamydia trachomatis: The urgent need for detection and treatment in women. J Womens Health Gend Based Med 2000; 9:339-343.
17. Kari L, Whitmire W, Crane D, et al. Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: Implication for a trachoma transmission-blocking vaccine. J Immunol 2009; 182:8063-8070.
18. Hafner L, Beagley K, Timms P. Chlamydia trachomatis infection: Host immune responses and potential vaccines. Mucosal Immunol 2008; 1:116-130.
19. Morrison R, Caldwell H. Immunity to murine chlamydial genital infection. Infect Immun 2002; 70:2741-2751.
20. Ballard RC, Fehler HG, Htun Y, et al. Coexistence of urethritis with genital ulcer disease in South Africa: Influence on provision of syndromic management. Sex Transm Infect 2002; 78:274-277.
21. Pépin J, Sobéla F, Deslandes S, et al. Etiology of urethral discharge in West Africa: The role of Mycoplasma genitalium and Trichomo-nas vaginalis. Bull World Health Organ 2001; 79:118-126.
22. Falk L, Fredlund H, Jensen JS. Symptomatic urethritis is more prevalent in men infected with Mycoplasma genitalium than with Chlamydia trachomatis. Sex Transm Infect 2004; 80:289-293.
23. Pépin J, Labbé AC, Khonde N, et al. Mycoplasma genitalium: An organism commonly associated with cervicitis among west African sex workers. Sex Transm Infect 2005; 81:67-72.
24. Schneider H, Coetzee DJ, Fehler HG, et al. Screening for sexually transmitted diseases in rural South African women. Sex Transm Infect 1998; 74(suppl 1):S147-S152.
25. Mayaud P, Ka-Gina G, Cornelissen J, et al. Validation of a WHO algorithm with risk assessment for the clinical management of vaginal discharge in Mwanza, Tanzania. Sex Transm Infect 1998; 74(suppl):S77-S84.
26. Corey L, Wald A, Celum CL, et al. The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: A review of two overlapping epidemics. J Acquir Immun Defic Syndr 2004; 35: 435-445.
27. Shisana O, Rehle T, Simbayi L, et al. South African National HIV Prevalence, HIV Incidence, Behaviour and Communication Survey, 2005. Cape Town, South Africa: HSRC Press, 2005.
28. Chandisarewa W, Stranix-Chibanda L, Chirapa E, et al. Routine offer of antenatal HIV testing ("opt-out" approach) to prevent mother-to-child transmission of HIV in urban Zimbabwe. Bull World Health Organ 2007; 85:843-850.